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Select item 91529931.

In a multi-institutional cohort of myeloid sarcomas, NFE2 mutation prevalence is lower than previously reported

Tauangtham Anekpuritanang, Matthew M. Klairmont, Joel Gradowski, Kohei Hagiwara, Nathanael G. Bailey, Pranil Chandra, Yiwei Liu, Heather L. Mulder, John Easton, Jinghui Zhang, Michael G. Martin, Anna B. Owczarczyk, Jennifer B. Dunlap, Guang Fan, Richard D. Press, Philipp W. Raess

Blood Adv. 2021 Dec 14; 5(23): 5057–5059. Published online 2021 Dec 3. doi: 10.1182/bloodadvances.2021004983

PMCID:: PMC9152993

Article PDF–579K

Select item 81650302.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80090483.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 67128064.

NFE2/miR-423-5p/TFF1 axis regulates high glucose-induced apoptosis in retinal pigment epithelial cells

Qing Xiao, Yinu Zhao, Jia Xu, Wen-Jie Li, Yu Chen, Hong-Jing Sun

BMC Mol Cell Biol. 2019; 20: 39. Published online 2019 Aug 27. doi: 10.1186/s12860-019-0223-2

PMCID:: PMC6712806

Abstract Article PDF–1.9M

Select item 64844615.

Altered NFE2 activity predisposes to leukemic transformation and myelosarcoma with AML-specific aberrations

Jonas Samuel Jutzi, Titiksha Basu, Maximilian Pellmann, Sandra Kaiser, Doris Steinemann, Mathijs A. Sanders, Adil S. A. Hinai, Annelieke Zeilemaker, Sarolta Bojtine Kovacs, Christoph Koellerer, Jenny Ostendorp, Konrad Aumann, Wei Wang, Emmanuel Raffoux, Bruno Cassinat, Lars Bullinger, Brigitte Schlegelberger, Peter J. M. Valk, Heike Luise Pahl

Blood. 2019 Apr 18; 133(16): 1766–1777. Prepublished online 2019 Feb 12. doi: 10.1182/blood-2018-09-875047

PMCID:: PMC6484461

Abstract Article

Select item 58247956.

The cytoprotective role of DJ-1 and p45 NFE2 against human primary alveolar type II cell injury and emphysema

Li Hui Tan, Karim Bahmed, Chih-Ru Lin, Nathaniel Marchetti, Sudhir Bolla, Gerard J. Criner, Steven Kelsen, Muniswamy Madesh, Beata Kosmider

Sci Rep. 2018; 8: 3555. Published online 2018 Feb 23. doi: 10.1038/s41598-018-21790-3

PMCID:: PMC5824795

Abstract Article PDF–4.0M

Select item 55111067.

Nuclear Factor Erythroid 2 Regulates Human HSC Self-Renewal and T Cell Differentiation by Preventing NOTCH1 Activation

Alessandro Di Tullio, Diana Passaro, Kevin Rouault-Pierre, Sukhveer Purewal, Dominique Bonnet

Stem Cell Reports. 2017 Jul 11; 9(1): 5–11. Published online 2017 Jun 22. doi: 10.1016/j.stemcr.2017.05.027

PMCID:: PMC5511106

Abstract Article PDF–1.1M

Select item 54966268.

Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals

Pedro M. Quirós, Miguel A. Prado, Nicola Zamboni, Davide D’Amico, Robert W. Williams, Daniel Finley, Steven P. Gygi, Johan Auwerx

J Cell Biol. 2017 Jul 3; 216(7): 2027–2045. doi: 10.1083/jcb.201702058

PMCID:: PMC5496626

Abstract Article PDF–3.1M

Select item 54775759.

p45 NF-E2 regulates syncytiotrophoblast differentiation by post-translational GCM1 modifications in human intrauterine growth restriction

Shrey Kohli, Juliane Hoffmann, Franziska Lochmann, Paulina Markmeyer, Hanna Huebner, Fabian B Fahlbusch, Moh'd Mohanad Al-Dabet, Ihsan Gadi, Jayakumar Manoharan, Michael Löttge, Ana C Zenclussen, Anat Aharon, Benjamin Brenner, Khurrum Shahzad, Matthias Ruebner, Berend Isermann

Cell Death Dis. 2017 Apr; 8(4): e2730. Published online 2017 Apr 6. doi: 10.1038/cddis.2017.127

PMCID:: PMC5477575

Abstract Article PDF–2.4M

Select item 506002210.

A novel role for nuclear factor-erythroid 2 in erythroid maturation by modulation of mitochondrial autophagy

Monika Gothwal, Julius Wehrle, Konrad Aumann, Vanessa Zimmermann, Albert Gründer, Heike L. Pahl

Haematologica. 2016 Sep; 101(9): 1054–1064. doi: 10.3324/haematol.2015.132589

PMCID:: PMC5060022

Abstract Article PDF–2.6M

Select item 426658811.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 411515412.

Networks of bZIP protein-protein interactions diversified over a billion years of evolution

Aaron W. Reinke, Jiyeon Baek, Orr Ashenberg, Amy E. Keating

Science. Author manuscript; available in PMC 2014 Jul 30.

Published in final edited form as: Science. 2013 May 10; 340(6133): 730–734. doi: 10.1126/science.1233465

PMCID:: PMC4115154

Abstract Article PDF–449K

Select item 396904113.

The Up-Regulation of miR-199b-5p in Erythroid Differentiation Is Associated with GATA-1 and NF-E2

Yuxia Li, Hua Bai, Zhongzu Zhang, Weihua li, Lei Dong, Xueju Wei, Yanni Ma, Junwu Zhang, Jia Yu, Guotao Sun, Fang Wang

Mol Cells. 2014 Mar 31; 37(3): 213–219. Published online 2014 Mar 6. doi: 10.14348/molcells.2014.2288

PMCID:: PMC3969041

Abstract Article PDF–656K

Select item 395236314.

RUNX1 and NF-E2 upregulation is not specific for MPNs, but is seen in polycythemic disorders with augmented HIF signaling

Katarina Kapralova, Lucie Lanikova, Felipe Lorenzo, Jihyun Song, Monika Horvathova, Vladimir Divoky, Josef T. Prchal

Blood. 2014 Jan 16; 123(3): 391–394. Prepublished online 2013 Dec 2. doi: 10.1182/blood-2013-10-534222

PMCID:: PMC3952363

Abstract Article

Select item 388060515.

A Genome- and Phenome-Wide Association Study to Identify Genetic Variants Influencing Platelet Count and Volume and their Pleiotropic Effects

Khader Shameer, Joshua C. Denny, Keyue Ding, Hayan Jouni, David R. Crosslin, Mariza de Andrade, Christopher G. Chute, Peggy Peissig, Jennifer A. Pacheco, Rongling Li, Lisa Bastarache, Abel N. Kho, Marylyn D Ritchie, Daniel R. Masys, Rex L. Chisholm, Eric B. Larson, Catherine A. McCarty, Dan M. Roden, Gail P. Jarvik, Iftikhar J. Kullo

Hum Genet. Author manuscript; available in PMC 2015 Jan 1.

Published in final edited form as: Hum Genet. 2014 Jan; 133(1): 10.1007/s00439-013-1355-7. Published online 2013 Sep 12. doi: 10.1007/s00439-013-1355-7

PMCID:: PMC3880605

Abstract Article PDF–2.2M

Select item 370190716.

Subcellular mislocalization of the transcription factor NF-E2 in erythroid cells discriminates prefibrotic primary myelofibrosis from essential thrombocythemia

Konrad Aumann, Anna-Verena Frey, Annette M. May, Dieter Hauschke, Clemens Kreutz, Jan P. Marx, Jens Timmer, Martin Werner, Heike L. Pahl

Blood. 2013 Jul 4; 122(1): 93–99. Prepublished online 2013 May 13. doi: 10.1182/blood-2012-11-463257

PMCID:: PMC3701907

Abstract Article

Select item 369661117.

Transcription factor nuclear factor erythroid-2 mediates expression of the cytokine interleukin 8, a known predictor of inferior outcome in patients with myeloproliferative neoplasms

Julius Wehrle, Thalia S. Seeger, Sven Schwemmers, Dietmar Pfeifer, Alla Bulashevska, Heike L. Pahl

Haematologica. 2013 Jul; 98(7): 1073–1080. doi: 10.3324/haematol.2012.071183

PMCID:: PMC3696611

Abstract Article PDF–1.3M

Select item 365975818.

Elevated Nuclear Factor Erythroid-2 Levels Promote Epo-Independent Erythroid Maturation and Recapitulate the Hematopoietic Stem Cell and Common Myeloid Progenitor Expansion Observed in Polycythemia Vera Patients

Ruzhica Bogeska, Heike L. Pahl

Stem Cells Transl Med. 2013 Feb; 2(2): 112–117. Published online 2013 Jan 22. doi: 10.5966/sctm.2012-0046

PMCID:: PMC3659758

Abstract Article PDF–2.3M

Select item 364650119.

MPN patients harbor recurrent truncating mutations in transcription factor NF-E2

Jonas S. Jutzi, Ruzhica Bogeska, Gorica Nikoloski, Corina A. Schmid, Thalia S. Seeger, Frank Stegelmann, Sven Schwemmers, Albert Gründer, Jan C. Peeken, Monika Gothwal, Julius Wehrle, Konrad Aumann, Kamar Hamdi, Christine Dierks, Wei Wang, Konstanze Döhner, Joop H. Jansen, Heike L. Pahl

J Exp Med. 2013 May 6; 210(5): 1003–1019. doi: 10.1084/jem.20120521

PMCID:: PMC3646501

Abstract Article PDF–4.3M

Select item 348889120.

Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/Maf

Yukako Ono, Yuhuan Wang, Hidenori Suzuki, Shinichiro Okamoto, Yasuo Ikeda, Mitsuru Murata, Mortimer Poncz, Yumiko Matsubara

Blood. 2012 Nov 1; 120(18): 3812–3821. Prepublished online 2012 Jul 31. doi: 10.1182/blood-2012-02-413617

PMCID:: PMC3488891

Abstract Article

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