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Items: 1 to 20 of 62

1.
TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN
Kaini Zhang, Chen Yang, Xin Zhou, Jin Liang, Jianjin Guo, Min Li, Yi Zhang, Shulin Shao, Peng Sun, Kai Li, Jingjing Huang, Fang Chen, Xiubin Liang, Dongming Su
Cell Mol Life Sci. 2023 Jun; 80(6): 168. Published online 2023 May 30. doi: 10.1007/s00018-023-04820-w
PMCID:
PMC10229743
AbstractArticlePDF–2.9M
2.
A Non-Canonical Role for the Glycosyltransferase Enzyme UGT2B17 as a Novel Constituent of the B Cell Receptor Signalosome
Antoine Wagner, Michèle Rouleau, Lyne Villeneuve, Trang Le, Cheryl Peltier, Éric P. Allain, Caroline Beaudoin, Sophie Tremblay, Fréderic Courtier, Flora Nguyen Van Long, Isabelle Laverdière, Éric Lévesque, Versha Banerji, Katrina Vanura, Chantal Guillemette
Cells. 2023 May; 12(9): 1295. Published online 2023 May 2. doi: 10.3390/cells12091295
PMCID:
PMC10177405
AbstractArticlePDF–5.4M
3.
Extensive metabolic consequences of human glycosyltransferase gene knockouts in prostate cancer
Michèle Rouleau, Flora Nguyen Van Long, Véronique Turcotte, Patrick Caron, Louis Lacombe, Armen Aprikian, Fred Saad, Michel Carmel, Simone Chevalier, Eric Lévesque, Chantal Guillemette
Br J Cancer. 2023 Jan 19; 128(2): 285–296. Published online 2022 Nov 8. doi: 10.1038/s41416-022-02040-w
PMCID:
PMC9902621
AbstractArticlePDF–1.0M
4.
Pangenomic analysis of Chinese gastric cancer
Yingyan Yu, Zhen Zhang, Xiaorui Dong, Ruixin Yang, Zhongqu Duan, Zhen Xiang, Jun Li, Guichao Li, Fazhe Yan, Hongzhang Xue, Du Jiao, Jinyuan Lu, Huimin Lu, Wenmin Zhang, Yangzhen Wei, Shiyu Fan, Jing Li, Jingya Jia, Jun Zhang, Jun Ji, Pixu Liu, Hui Lu, Hongyu Zhao, Saijuan Chen, Chaochun Wei, Hongzhuan Chen, Zhenggang Zhu
Nat Commun. 2022; 13: 5412. Published online 2022 Sep 15. doi: 10.1038/s41467-022-33073-7
PMCID:
PMC9477819
AbstractArticlePDF–3.8M
5.
Identification of UDP-Glucuronosyltransferase 2B15 (UGT2B15) as a Target for IGF1 and Insulin Action
Rive Sarfstein, Karthik Nagaraj, Shivang Parikh, Carmit Levy, Zvi Laron, Dafna Benayahu, Haim Werner
Cells. 2022 May; 11(10): 1627. Published online 2022 May 12. doi: 10.3390/cells11101627
PMCID:
PMC9139319
AbstractArticlePDF–2.6M
6.
TRIP12 Ubiquitination of Glucocerebrosidase Contributes to Neurodegeneration in Parkinson’s Disease
Bo Am Seo, Donghoon Kim, Heehong Hwang, Min Seong Kim, Shi-Xun Ma, Seung-Hwan Kwon, Sin Ho Kweon, Hu Wang, Je Min Yoo, Seulah Choi, Sang Ho Kwon, Sung-Ung Kang, Tae-In Kam, Kwangsoo Kim, Senthilkumar S Karuppagounder, Bong Gu Kang, Saebom Lee, Hyejin Park, Sangjune Kim, Wei Yan, Yong-Shi Li, Sheng-Han Kuo, Javier Redding-Ochoa, Olga Pletnikova, Juan C. Troncoso, Gabsang Lee, Xiaobo Mao, Valina L. Dawson, Ted M. Dawson, Han Seok Ko
Neuron. Author manuscript; available in PMC 2022 Dec 1.
Published in final edited form as: Neuron. 2021 Dec 1; 109(23): 3758–3774.e11. Published online 2021 Oct 12. doi: 10.1016/j.neuron.2021.09.031
PMCID:
PMC8639668
AbstractArticlePDF–2.6M
7.
Potential Assessment of UGT2B17 Inhibition by Salicylic Acid in Human Supersomes In Vitro
Hassan Salhab, Declan P. Naughton, James Barker
Molecules. 2021 Aug; 26(15): 4410. Published online 2021 Jul 21. doi: 10.3390/molecules26154410
PMCID:
PMC8348562
AbstractArticlePDF–774K
8.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
9.
Expression of UDP Glucuronosyltransferases 2B15 and 2B17 is associated with methylation status in prostate cancer cells
Farideh Shafiee-Kermani, Skyla T. Carney, Dereje Jima, Utibe C. Utin, LaNeisha B. Farrar, Melvin O. Oputa, Marcono R. Hines, Jr. H. Karimi Kinyamu, Kevin W. Trotter, Trevor K. Archer, Cathrine Hoyo, Beverly H. Koller, Stephen J. Freedland, Delores J. Grant
Epigenetics. 2021; 16(3): 289–299. Published online 2020 Jul 27. doi: 10.1080/15592294.2020.1795601
PMCID:
PMC7901543
AbstractArticlePDF–1.0M
10.
UGT2B17 modifies drug response in chronic lymphocytic leukaemia
Eric P. Allain, Michèle Rouleau, Katrina Vanura, Sophie Tremblay, Joanie Vaillancourt, Vincent Bat, Patrick Caron, Lyne Villeneuve, Adrien Labriet, Véronique Turcotte, Trang Le, Medhat Shehata, Susanne Schnabl, Dita Demirtas, Rainer Hubmann, Charles Joly-Beauparlant, Arnaud Droit, Ulrich Jäger, Philipp B. Staber, Eric Lévesque, Chantal Guillemette
Br J Cancer. 2020 Jul 21; 123(2): 240–251. Published online 2020 May 18. doi: 10.1038/s41416-020-0887-6
PMCID:
PMC7374097
AbstractArticlePDF–1.0M
11.
The correlation between UDP-glucuronosyltransferase polymorphisms and environmental endocrine disruptors levels in polycystic ovary syndrome patients
Yunyao Luo, Ying Nie, Lu Tang, Charles C. Xu, Liangzhi Xu
Medicine (Baltimore) 2020 Mar; 99(11): e19444. Published online 2020 Mar 13. doi: 10.1097/MD.0000000000019444
PMCID:
PMC7220089
AbstractArticlePDF–318K
12.
Coordinated Regulation of UGT2B15 Expression by Long Noncoding RNA LINC00574 and hsa-miR-129-5p in HepaRG Cells
Dianke Yu, Jing Chen, Si Chen, Lin Xu, Leihong Wu, Dongying Li, Jiao Luo, Yuan Jin, Yanjie Zhao, Bridgett Knox, William H. Tolleson, Xubing Wang, Lei Guo, Weida Tong, Baitang Ning
Drug Metab Dispos. 2020 Apr; 48(4): 297–306. Published online 2020 Apr. doi: 10.1124/dmd.119.090043
Correction in:
Drug Metab Dispos. 2020 May; 48(5): 386.
PMCID:
PMC7153565
AbstractArticlePDF–1.3M
13.
Alternative promoters control UGT2B17-dependent androgen catabolism in prostate cancer and its influence on progression
Eric Lévesque, Adrien Labriet, Hélène Hovington, Éric P. Allain, Luciana Melo-Garcia, Michèle Rouleau, Hervé Brisson, Véronique Turcotte, Patrick Caron, Lyne Villeneuve, Mickaël Leclercq, Arnaud Droit, Etienne Audet-Walsh, David Simonyan, Yves Fradet, Louis Lacombe, Chantal Guillemette
Br J Cancer. 2020 Mar 31; 122(7): 1068–1076. Published online 2020 Feb 12. doi: 10.1038/s41416-020-0749-2
PMCID:
PMC7109100
AbstractArticlePDF–1.6M
14.
Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development
Pu Wang, Feng Yan, Zhijun Li, Yanbao Yu, Scott E. Parnell, Yue Xiong
J Clin Invest. 2019 Oct 1; 129(10): 4393–4407. Published online 2019 Sep 9. doi: 10.1172/JCI129107
PMCID:
PMC6763242
AbstractArticlePDF–12M
15.
UGT2B17 and miR-224 contribute to hormone dependency trends in adenocarcinoma and squamous cell carcinoma of esophagus
Xiangyao Lian, Ancha Baranova, Jimmy Ngo, Guiping Yu, Hongbao Cao
Biosci Rep. 2019 Jul 31; 39(7): BSR20190472. Prepublished online 2019 Jun 4. Published online 2019 Jul 5. doi: 10.1042/BSR20190472
PMCID:
PMC6609598
AbstractArticlePDF–703K
16.
Exemestane may be less detrimental than letrozole to bone health in women homozygous for the UGT2B17*2 gene deletion
Landry K. Kamdem, Jingyue Xi, Brandi L. Clark, Bryana J. Gregory, Kelley M. Kidwell, Ana-Maria Storniolo, Vered Stearns, Daniel F Hayes, Christina L. Gersch, James M. Rae, N. Lynn Henry, Daniel L. Hertz
Breast Cancer Res Treat. Author manuscript; available in PMC 2020 Jun 1.
Published in final edited form as: Breast Cancer Res Treat. 2019 Jun; 175(2): 297–303. Published online 2019 Feb 12. doi: 10.1007/s10549-019-05158-3
PMCID:
PMC6534458
AbstractArticlePDF–375K
17.
Identification and validation of the microRNA response elements in the 3’-untranslated region of the UDP glucuronosyltransferase (UGT) 2B7 and 2B15 genes by a functional genomics approach
Ioannis Papageorgiou, Michael H. Court
Biochem Pharmacol. Author manuscript; available in PMC 2018 Dec 15.
Published in final edited form as: Biochem Pharmacol. 2017 Dec 15; 146: 199–213. Published online 2017 Sep 28. doi: 10.1016/j.bcp.2017.09.013
PMCID:
PMC6188638
AbstractArticlePDF–1.1M
18.
Bioinformatic analysis suggests that UGT2B15 activates the Hippo-YAP signaling pathway leading to the pathogenesis of gastric cancer
Xuanmin Chen, Defeng Li, Nannan Wang, Meifeng Yang, Aijun Liao, Shuling Wang, Guangsheng Hu, Bing Zeng, Yuhong Yao, Diqun Liu, Han Liu, Weiwei Zhou, Weisheng Xiao, Peiyuan Li, Chen Ming, Song Ping, Pingfang Chen, Li Jing, Yu Bai, Jun Yao
Oncol Rep. 2018 Oct; 40(4): 1855–1862. Published online 2018 Jul 26. doi: 10.3892/or.2018.6604
PMCID:
PMC6111708
AbstractArticlePDF–759K
19.
Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex
Deepak Kumar Bhatt, Abdul Basit, Haeyoung Zhang, Andrea Gaedigk, Seung-been Lee, Katrina G. Claw, Aanchal Mehrotra, Amarjit Singh Chaudhry, Robin E. Pearce, Roger Gaedigk, Ulrich Broeckel, Timothy A. Thornton, Deborah A. Nickerson, Erin G. Schuetz, John K. Amory, J. Steven Leeder, Bhagwat Prasad
Drug Metab Dispos. 2018 Jun; 46(6): 888–896. Published online 2018 Jun. doi: 10.1124/dmd.118.080952
PMCID:
PMC5938891
AbstractArticlePDF–896K
20.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M

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