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Items: 1 to 20 of 25

1.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
2.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
3.
A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells
Xue Chen, Haidong Yao, Muhammad Kashif, Gwladys Revêchon, Maria Eriksson, Jianjiang Hu, Ting Wang, Yiran Liu, Elin Tüksammel, Staffan Strömblad, Ian M Ahearn, Mark R Philips, Clotilde Wiel, Mohamed X Ibrahim, Martin O Bergo
eLife. 2021; 10: e63284. Published online 2021 Feb 2. doi: 10.7554/eLife.63284
PMCID:
PMC7853716
AbstractArticlePDF–783K
4.
Isoprenylcysteine Carboxyl Methyltransferase and Its Substrate Ras Are Critical Players Regulating TLR-Mediated Inflammatory Responses
Woo Seok Yang, Han Gyung Kim, Eunji Kim, Sang Yun Han, Nur Aziz, Young-Su Yi, Sunggyu Kim, Yunmi Lee, Byong Chul Yoo, Jeung-Whan Han, Narayanan Parameswaran, Ji Hye Kim, Jae Youl Cho
Cells. 2020 May; 9(5): 1216. Published online 2020 May 14. doi: 10.3390/cells9051216
PMCID:
PMC7291029
AbstractArticlePDF–6.3M
5.
Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss
Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs
Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931
PMCID:
PMC7227028
AbstractArticlePDF–5.4M
6.
Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras
Tim Wang, Haiyan Yu, Nicholas W. Hughes, Bingxu Liu, Arek Kendirli, Klara Klein, Walter W. Chen, Eric S. Lander, David M. Sabatini
Cell. Author manuscript; available in PMC 2018 Feb 23.
Published in final edited form as: Cell. 2017 Feb 23; 168(5): 890–903.e15. Published online 2017 Feb 2. doi: 10.1016/j.cell.2017.01.013
PMCID:
PMC5445660
AbstractArticlePDF–2.2M
7.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
8.
Deficiency of Isoprenylcysteine Carboxyl Methyltransferase (ICMT) Leads to Progressive Loss of Photoreceptor Function
Jeffrey R. Christiansen, Nachiket D. Pendse, Saravanan Kolandaivelu, Martin O. Bergo, Stephen G. Young, Visvanathan Ramamurthy
J Neurosci. 2016 May 4; 36(18): 5107–5114. doi: 10.1523/JNEUROSCI.0176-16.2016
PMCID:
PMC4854971
AbstractArticlePDF–2.4M
9.
Targeting Isoprenylcysteine Methylation Ameliorates Disease in a Mouse Model of Progeria
Mohamed X. Ibrahim, Volkan I. Sayin, Murali K. Akula, Meng Liu, Loren G. Fong, Stephen G. Young, Martin O. Bergo
Science. Author manuscript; available in PMC 2015 Jan 15.
Published in final edited form as: Science. 2013 Jun 14; 340(6138): 1330–1333. Published online 2013 May 16. doi: 10.1126/science.1238880
PMCID:
PMC4295631
AbstractArticlePDF–1.2M
10.
Isoprenylcysteine carboxylmethyltransferase deficiency exacerbates KRAS-driven pancreatic neoplasia via Notch suppression
Helen Court, Marc Amoyel, Michael Hackman, Kyoung Eun Lee, Ruliang Xu, George Miller, Dafna Bar-Sagi, Erika A. Bach, Martin O. Bergö, Mark R. Philips
J Clin Invest. 2013 Nov 1; 123(11): 4681–4694. Published online 2013 Oct 8. doi: 10.1172/JCI65764
PMCID:
PMC3809775
AbstractArticlePDF–6.6M
11.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
12.
Topology of Mammalian Isoprenylcysteine Carboxyl Methyltransferase Determined in Live Cells with a Fluorescent Probe
Latasha P. Wright, Helen Court, Adam Mor, Ian M. Ahearn, Patrick J. Casey, Mark R. Philips
Mol Cell Biol. 2009 Apr; 29(7): 1826–1833. Published online 2009 Jan 21. doi: 10.1128/MCB.01719-08
PMCID:
PMC2655619
AbstractArticlePDF–2.0M
13.
Inactivating Icmt ameliorates K-RAS–induced myeloproliferative disease
Annika M. Wahlstrom, Briony A. Cutts, Meng Liu, Annika Lindskog, Christin Karlsson, Anna-Karin M. Sjogren, Karin M. E. Andersson, Stephen G. Young, Martin O. Bergo
Blood. 2008 Aug 15; 112(4): 1357–1365. Prepublished online 2008 May 23. doi: 10.1182/blood-2007-06-094060
PMCID:
PMC2515151
AbstractArticle
14.
Endoproteolytic Processing of RhoA by Rce1 Is Required for the Cleavage of RhoA by Yersinia enterocolitica Outer Protein T
Florian Fueller, Martin O. Bergo, Stephen G. Young, Klaus Aktories, Gudula Schmidt
Infect Immun. 2006 Mar; 74(3): 1712–1717. doi: 10.1128/IAI.74.3.1712-1717.2006
PMCID:
PMC1418669
AbstractArticlePDF–280K
15.
Genomic Analysis of Mouse Retinal Development
Seth Blackshaw, Sanjiv Harpavat, Jeff Trimarchi, Li Cai, Haiyan Huang, Winston P Kuo, Griffin Weber, Kyungjoon Lee, Rebecca E Fraioli, Seo-Hee Cho, Rachel Yung, Elizabeth Asch, Lucila Ohno-Machado, Wing H Wong, Constance L Cepko
PLoS Biol. 2004 Sep; 2(9): e247. Published online 2004 Jun 29. doi: 10.1371/journal.pbio.0020247
PMCID:
PMC439783
AbstractArticlePDF–975K
16.
Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf
Martin O. Bergo, Bryant J. Gavino, Christine Hong, Anne P. Beigneux, Martin McMahon, Patrick J. Casey, Stephen G. Young
J Clin Invest. 2004 Feb 15; 113(4): 539–550. doi: 10.1172/JCI18829
PMCID:
PMC338259
AbstractArticlePDF–4.4M
17.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M
18.
Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes
Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki
Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100
PMCID:
PMC310980
AbstractArticlePDF–1.4M
19.
GenePaint.org: an atlas of gene expression patterns in the mouse embryo
Axel Visel, Christina Thaller, Gregor Eichele
Nucleic Acids Res. 2004 Jan 1; 32(Database issue): D552–D556. doi: 10.1093/nar/gkh029
PMCID:
PMC308763
AbstractArticlePDF–253K
20.
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands
Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100
Correction in:
Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.
PMCID:
PMC283554
AbstractArticlePDF–481K

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