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Select item 115808351.

Generation of salivary glands derived from pluripotent stem cells via conditional blastocyst complementation

Junichi Tanaka, Akihiro Miura, Yuko Shimamura, Youngmin Hwang, Dai Shimizu, Yuri Kondo, Anri Sawada, Hemanta Sarmah, Zurab Ninish, Kenji Mishima, Munemasa Mori

Cell Rep. Author manuscript; available in PMC 2024 Nov 21.

Published in final edited form as: Cell Rep. 2024 Jun 25; 43(6): 114340. Published online 2024 Jun 11. doi: 10.1016/j.celrep.2024.114340

PMCID:: PMC11580835

Abstract Article PDF–2.8M

Select item 114239202.

A cell-autonomous role for primary cilium-mediated signaling in long-range commissural axon guidance

Alexandre Dumoulin, Nicole H. Wilson, Kerry L. Tucker, Esther T. Stoeckli

Development. 2024 Sep 1; 151(17): dev202788. Published online 2024 Sep 5. doi: 10.1242/dev.202788

PMCID:: PMC11423920

Abstract Article

Select item 113854713.

Identification of an embryonic differentiation stage marked by Sox1 and FoxA2 co-expression using combined cell tracking and high dimensional protein imaging

Geethika Arekatla, Stavroula Skylaki, David Corredor Suarez, Hartland Jackson, Denis Schapiro, Stefanie Engler, Markus Auler, German Camargo Ortega, Simon Hastreiter, Andreas Reimann, Dirk Loeffler, Bernd Bodenmiller, Timm Schroeder

Nat Commun. 2024; 15: 7860. Published online 2024 Sep 9. doi: 10.1038/s41467-024-52069-z

PMCID:: PMC11385471

Abstract Article PDF–6.4M

Select item 108952594.

Skeletal growth is enhanced by a shared role for SOX8 and SOX9 in promoting reserve chondrocyte commitment to columnar proliferation

Arnaud N. Molin, Romain Contentin, Marco Angelozzi, Anirudha Karvande, Ranjan Kc, Abdul Haseeb, Chantal Voskamp, Charles de Charleroy, Véronique Lefebvre

Proc Natl Acad Sci U S A. 2024 Feb 20; 121(8): e2316969121. Published online 2024 Feb 12. doi: 10.1073/pnas.2316969121

PMCID:: PMC10895259

Abstract Article PDF–17M

Select item 107743625.

miR-195b is required for proper cellular homeostasis in the elderly

Maria del Mar Muñoz-Gallardo, Carlos Garcia-Padilla, Cristina Vicente-Garcia, Jaime Carvajal, Amelia Arenega, Diego Franco

Sci Rep. 2024; 14: 810. Published online 2024 Jan 8. doi: 10.1038/s41598-024-51256-8

PMCID:: PMC10774362

Abstract Article PDF–3.7M

Select item 107650596.

Pioneer Factor Foxa2 Mediates Chromatin Conformation Changes for Activation of Bile Acid Targets of FXR

Yi Hao, Lu Han, Anqi Wu, Irina M. Bochkis

Cell Mol Gastroenterol Hepatol. 2024; 17(2): 237–249. Published online 2023 Oct 24. doi: 10.1016/j.jcmgh.2023.10.009

PMCID:: PMC10765059

Abstract Article PDF–4.9M

Select item 107243937.

FOXA2 Suppression by TRIM36 Exerts Anti‐Tumor Role in Colorectal Cancer Via Inducing NRF2/GPX4‐Regulated Ferroptosis

Xin Liu, Chunli Yan, Chunxiao Chang, Fansong Meng, Wenjie Shen, Song Wang, Yi Zhang

Adv Sci (Weinh) 2023 Dec; 10(35): 2304521. Published online 2023 Oct 24. doi: 10.1002/advs.202304521

PMCID:: PMC10724393

Abstract Article PDF–11M

Select item 107107738.

Foxa2 attenuates steatosis and inhibits the NF-κB/IKK signaling pathway in nonalcoholic fatty liver disease

Li Yang, Qiang Ma, Jiayu Chen, Xiangcai Kong, Xiaohui Yu, Wei Wang

PeerJ. 2023; 11: e16466. Published online 2023 Dec 7. doi: 10.7717/peerj.16466

PMCID:: PMC10710773

Abstract Article PDF–52M

Select item 106627149.

Context-dependent ciliary regulation of hedgehog pathway repression in tissue morphogenesis

Sun-Hee Hwang, Kevin Andrew White, Bandarigoda Nipunika Somatilaka, Baolin Wang, Saikat Mukhopadhyay

PLoS Genet. 2023 Nov; 19(11): e1011028. Published online 2023 Nov 9. doi: 10.1371/journal.pgen.1011028

PMCID:: PMC10662714

Abstract Article PDF–5.4M

Select item 1064296810.

Conditional blastocyst complementation of a defective Foxa2 lineage efficiently promotes the generation of the whole lung

Akihiro Miura, Hemanta Sarmah, Junichi Tanaka, Youngmin Hwang, Anri Sawada, Yuko Shimamura, Takehiro Otoshi, Yuri Kondo, Yinshan Fang, Dai Shimizu, Zurab Ninish, Jake Le Suer, Nicole C Dubois, Jennifer Davis, Shinichi Toyooka, Jun Wu, Jianwen Que, Finn J Hawkins, Chyuan-Sheng Lin, Munemasa Mori

eLife. 2023; 12: e86105. Published online 2023 Oct 20. doi: 10.7554/eLife.86105

PMCID:: PMC10642968

Abstract Article PDF–22M

Select item 1061762511.

Caudal Fgfr1 disruption produces localised spinal mis-patterning and a terminal myelocystocele-like phenotype in mice

Eirini Maniou, Faduma Farah, Abigail R. Marshall, Zoe Crane-Smith, Andrea Krstevski, Athanasia Stathopoulou, Nicholas D. E. Greene, Andrew J. Copp, Gabriel L. Galea

Development. 2023 Oct 1; 150(19): dev202139. Published online 2023 Oct 10. doi: 10.1242/dev.202139

PMCID:: PMC10617625

Abstract Article

Select item 1055382812.

Key transcriptional effectors of the pancreatic acinar phenotype and oncogenic transformation

Ana Azevedo-Pouly, Michael A. Hale, Galvin H. Swift, Chinh Q. Hoang, Tye G. Deering, Jumin Xue, Thomas M. Wilkie, L. Charles Murtaugh, Raymond J. MacDonald

PLoS One. 2023; 18(10): e0291512. Published online 2023 Oct 5. doi: 10.1371/journal.pone.0291512

PMCID:: PMC10553828

Abstract Article PDF–6.4M

Select item 1052156613.

Hepatocyte-specific HDAC3 ablation promotes hepatocellular carcinoma in females by suppressing Foxa1/2

Yahong Xu, Yongjie Zhu, Zhenru Wu, Shengfu Li, Mingyang Shao, Qing Tao, Qing Xu, Yuwei Chen, Yuke Shu, Menglin Chen, Yongjie Zhou, Yujun Shi

BMC Cancer. 2023; 23: 906. Published online 2023 Sep 26. doi: 10.1186/s12885-023-11393-1

PMCID:: PMC10521566

Abstract Article PDF–11M

Select item 1049745714.

A niche for axial stem cells - A cellular perspective in amniotes

Tatiana Solovieva, Valerie Wilson, Claudio D. Stern

Dev Biol. 2022 Oct; 490: 13–21. doi: 10.1016/j.ydbio.2022.06.015

PMCID:: PMC10497457

Abstract Article PDF–1.0M

Select item 1046508715.

Single-Cell RNA Sequencing of Sox17-Expressing Lineages Reveals Distinct Gene Regulatory Networks and Dynamic Developmental Trajectories

Linh T Trinh, Anna B Osipovich, Bryan Liu, Shristi Shrestha, Jean-Philippe Cartailler, Christopher V E Wright, Mark A Magnuson

Stem Cells. 2023 Jun; 41(6): 643–657. Published online 2023 Apr 21. doi: 10.1093/stmcls/sxad030

PMCID:: PMC10465087

Abstract Article PDF–41M

Select item 1039399616.

TRIM28 modulates nuclear receptor signaling to regulate uterine function

Rong Li, Tianyuan Wang, Ryan M. Marquardt, John P. Lydon, San-Pin Wu, Francesco J. DeMayo

Nat Commun. 2023; 14: 4605. Published online 2023 Aug 1. doi: 10.1038/s41467-023-40395-7

PMCID:: PMC10393996

Abstract Article PDF–11M

Select item 1035703617.

TMEM132A regulates mouse hindgut morphogenesis and caudal development

Huiqing Zeng, Aimin Liu

Development. 2023 Jul 15; 150(14): dev201630. Published online 2023 Jul 13. doi: 10.1242/dev.201630

PMCID:: PMC10357036

Abstract Article

Select item 1033593718.

Spatiotemporal transcriptomic maps of whole mouse embryos at the onset of organogenesis

Abhishek Sampath Kumar, Luyi Tian, Adriano Bolondi, Amèlia Aragonés Hernández, Robert Stickels, Helene Kretzmer, Evan Murray, Lars Wittler, Maria Walther, Gabriel Barakat, Leah Haut, Yechiel Elkabetz, Evan Z. Macosko, Léo Guignard, Fei Chen, Alexander Meissner

Nat Genet. 2023; 55(7): 1176–1185. Published online 2023 Jul 6. doi: 10.1038/s41588-023-01435-6