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Select item 109500371.

ANGPTL7 and Its Role in IOP and Glaucoma

Suzette Farber-Katz Brown, Hien Nguyen, Philip Mzyk, Michael L. De Ieso, Andrea M. Unser, Ian Brown, Pujhitha Ramesh, Hira Afzaal, Feryan Ahmed, Karen Y. Torrejon, Alan Nhan, Dalton Markrush, Tom Daly, Ellie Knecht, William McConaughy, Sara Halmos, Zhiquan Lucy Liu, Rachel Rennard, Andrew Peterson, W. Daniel Stamer

Invest Ophthalmol Vis Sci. 2024 Mar; 65(3): 22. Published online 2024 Mar 18. doi: 10.1167/iovs.65.3.22

PMCID:: PMC10950037

Abstract Article PDF–1.6M

Select item 106440732.

The non-cell-autonomous function of ID1 promotes AML progression via ANGPTL7 from the microenvironment

Ming-Yue Fei, Yong Wang, Bin-He Chang, Kai Xue, Fangyi Dong, Dan Huang, Xi-Ya Li, Zi-Juan Li, Cheng-Long Hu, Ping Liu, Ji-Chuan Wu, Peng-Cheng Yu, Ming-Hua Hong, Shu-Bei Chen, Chun-Hui Xu, Bing-Yi Chen, Yi-Lun Jiang, Na Liu, Chong Zhao, Jia-Cheng Jin, Dan Hou, Xin-Chi Chen, Yi-Yi Ren, Chu-Han Deng, Jia-Ying Zhang, Li-juan Zong, Rou-Jia Wang, Fei-Fei Gao, Hui Liu, Qun-Ling Zhang, Ling-Yun Wu, Jinsong Yan, Shuhong Shen, Chun-Kang Chang, Xiao-Jian Sun, Lan Wang

Blood. 2023 Sep 7; 142(10): 903–917. Published online 2023 Jun 18. doi: 10.1182/blood.2022019537

PMCID:: PMC10644073

Abstract Article

Select item 103603923.

Rare protective variants and glaucoma-relevant cell stressors modulate Angiopoietin-like 7 expression

Inas F Aboobakar, Edward Ryan A Collantes, Michael A Hauser, W Daniel Stamer, Janey L Wiggs

Hum Mol Genet. 2023 Aug 1; 32(15): 2523–2531. Published online 2023 May 23. doi: 10.1093/hmg/ddad083

PMCID:: PMC10360392

Abstract Article PDF–1006K

Select item 100137504.

Metastasis from the tumor interior and necrotic core formation are regulated by breast cancer-derived angiopoietin-like 7

Ami Yamamoto, Yin Huang, Brad A. Krajina, Margaux McBirney, Andrea E. Doak, Sixuan Qu, Carolyn L. Wang, Michael C. Haffner, Kevin J. Cheung

Proc Natl Acad Sci U S A. 2023 Mar 7; 120(10): e2214888120. Published online 2023 Feb 28. doi: 10.1073/pnas.2214888120

PMCID:: PMC10013750

Abstract Article PDF–8.0M

Select item 95299595.

ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma

Kavita Praveen, Gaurang C. Patel, Lauren Gurski, Ariane H. Ayer, Trikaladarshi Persaud, Matthew D. Still, Lawrence Miloscio, Tavé Van Zyl, Silvio Alessandro Di Gioia, Ben Brumpton, Kristi Krebs, Bjørn Olav Åsvold, Esteban Chen, Venkata R. M. Chavali, Wen Fury, Harini V. Gudiseva, Sarah Hyde, Eric Jorgenson, Stephanie Lefebvre, Dadong Li, Alexander Li, James Mclninch, Brijeshkumar Patel, Jeremy S. Rabinowitz, Rebecca Salowe, Claudia Schurmann, Anne-Sofie Seidelin, Eli Stahl, Dylan Sun, Tanya M. Teslovich, Anne Tybjærg-Hansen, Cristen Willer, Scott Waldron, Sabrina Walley, Hua Yang, Sarthak Zaveri, Regeneron Genetics Center, GHS-RGC DiscovEHR Collaboration, Estonian Biobank Research Team, Ying Hu, Kristian Hveem, Olle Melander, Lili Milani, Stefan Stender, Joan M. O’Brien, Marcus B. Jones, Gonçalo R. Abecasis, Michael N. Cantor, Jonathan Weyne, Katia Karalis, Aris Economides, Giusy Della Gatta, Manuel A. Ferreira, George D. Yancopoulos, Aris Baras, Carmelo Romano, Giovanni Coppola

Commun Biol. 2022; 5: 1051. Published online 2022 Oct 3. doi: 10.1038/s42003-022-03932-6

PMCID:: PMC9529959

Abstract Article PDF–6.1M

Select item 93966196.

Increased plasma ANGPTL7 levels with increased obstructive sleep apnea severity

M. Leentjens, Abdulmohsen Alterki, Mohamed Abu-Farha, P. F. N. Bosschieter, CAL. de Raaff, CEE. de Vries, Eman Al Shawaf, Thangavel Alphonse Thanaraj, Irina Al-Khairi, Preethi Cherian, Arshad Channanath, Sina Kavalakatt, B. A. van Wagensveld, N. de Vries, Jehad Abubaker

Front Endocrinol (Lausanne) 2022; 13: 922425. Published online 2022 Aug 9. doi: 10.3389/fendo.2022.922425

PMCID:: PMC9396619

Abstract Article PDF–1.3M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 77194868.

Cord Blood Levels of Angiopoietin-Like 7 (ANGPTL7) in Preterm Infants

Xin Xia, Zhuxiao Ren, Longli Yan, Xuaner Zheng, Haoming Yang, Memnmeng Kang, Huiheng Yan, Zhicheng Zhong, Fang Xu, Jiayu Miao, Jianlan Wang, Yongsheng Li, Wei Wei, Jie Yang

Biomed Res Int. 2020; 2020: 1892458. Published online 2020 Nov 27. doi: 10.1155/2020/1892458

PMCID:: PMC7719486

Abstract Article PDF–398K

Select item 71999289.

Rare protein-altering variants in ANGPTL7 lower intraocular pressure and protect against glaucoma

Yosuke Tanigawa, Michael Wainberg, Juha Karjalainen, Tuomo Kiiskinen, Guhan Venkataraman, Susanna Lemmelä, Joni A. Turunen, Robert R. Graham, Aki S. Havulinna, Markus Perola, Aarno Palotie, FinnGen, Mark J. Daly, Manuel A. Rivas

PLoS Genet. 2020 May; 16(5): e1008682. Published online 2020 May 5. doi: 10.1371/journal.pgen.1008682

PMCID:: PMC7199928

Abstract Article PDF–1.1M

Select item 553161110.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 533879411.

Plasma and adipose tissue level of angiopoietin-like 7 (ANGPTL7) are increased in obesity and reduced after physical exercise

Mohamed Abu-Farha, Preethi Cherian, Irina Al-Khairi, Dhanya Madhu, Ali Tiss, Samia Warsam, Asma Alhubail, Devarajan Sriraman, Faisal Al-Refaei, Jehad Abubaker

PLoS One. 2017; 12(3): e0173024. Published online 2017 Mar 6. doi: 10.1371/journal.pone.0173024

PMCID:: PMC5338794

Abstract Article PDF–2.1M

Select item 526093912.

Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease

Felipe Roberti Teixeira, Suzanne J. Randle, Shachi P. Patel, Tycho E.T. Mevissen, Grasilda Zenkeviciute, Tie Koide, David Komander, Heike Laman

Biochem J. 2016 Oct 15; 473(20): 3563–3580. Prepublished online 2016 Aug 8. Published online 2016 Oct 11. doi: 10.1042/BCJ20160387

PMCID:: PMC5260939

Abstract Article PDF–1.1M

Select item 444121513.

Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders

Nidhi Sahni, Song Yi, Mikko Taipale, Juan I. Fuxman Bass, Jasmin Coulombe-Huntington, Fan Yang, Jian Peng, Jochen Weile, Georgios I. Karras, Yang Wang, István A. Kovács, Atanas Kamburov, Irina Krykbaeva, Mandy H. Lam, George Tucker, Vikram Khurana, Amitabh Sharma, Yang-Yu Liu, Nozomu Yachie, Quan Zhong, Yun Shen, Alexandre Palagi, Adriana San-Miguel, Changyu Fan, Dawit Balcha, Amelie Dricot, Daniel M. Jordan, Jennifer M. Walsh, Akash A. Shah, Xinping Yang, Ani Stoyanova, Alex Leighton, Michael A. Calderwood, Yves Jacob, Michael E. Cusick, Kourosh Salehi-Ashtiani, Luke J. Whitesell, Shamil Sunyaev, Bonnie Berger, Albert-László Barabási, Benoit Charloteaux, David E. Hill, Tong Hao, Frederick P. Roth, Yu Xia, Albertha J.M. Walhout, Susan Lindquist, Marc Vidal

Cell. Author manuscript; available in PMC 2016 Apr 23.

Published in final edited form as: Cell. 2015 Apr 23; 161(3): 647–660. doi: 10.1016/j.cell.2015.04.013

PMCID:: PMC4441215

Abstract Article PDF–1.2M

Select item 430655114.

Angiopoietin-Like 7 Is an Anti-Angiogenic Protein Required to Prevent Vascularization of the Cornea

Tetsuya Toyono, Tomohiko Usui, Seiichi Yokoo, Yukako Taketani, Suguru Nakagawa, Masahiko Kuroda, Satoru Yamagami, Shiro Amano

PLoS One. 2015; 10(1): e0116838. Published online 2015 Jan 26. doi: 10.1371/journal.pone.0116838

PMCID:: PMC4306551

Abstract Article PDF–416K

Select item 412005915.

Evidence for a role of angiopoietin-like 7 (ANGPTL7) in extracellular matrix formation of the human trabecular meshwork: implications for glaucoma

Núria Comes, LaKisha K. Buie, Teresa Borrás

Genes Cells. Author manuscript; available in PMC 2014 Aug 4.

Published in final edited form as: Genes Cells. 2011 Feb; 16(2): 243–259. Published online 2010 Dec 30. doi: 10.1111/j.1365-2443.2010.01483.x

PMCID:: PMC4120059

Abstract Article PDF–957K

Select item 319082616.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907