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Items: 1 to 20 of 63

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Smurf1 Modulates Smad Signaling Pathway in Fibrotic Cataract Formation
Fanying Jiang, Yuanfan Yang, Yan Ni, Yingyan Qin, Fa Yuan, Rong Ju, Mingxing Wu
Invest Ophthalmol Vis Sci. 2024 Feb; 65(2): 18. Published online 2024 Feb 7. doi: 10.1167/iovs.65.2.18
PMCID:
PMC10854413
AbstractArticlePDF–4.3M
3.
Talin-1 inhibits Smurf1-mediated Stat3 degradation to modulate β-cell proliferation and mass in mice
Xiaoting Hou, Yangshan Chen, Bo Zhou, Wanze Tang, Zhen Ding, Litong Chen, Yun Wu, Hongyu Yang, Changzheng Du, Dazhi Yang, Guixing Ma, Huiling Cao
Cell Death Dis. 2023 Oct; 14(10): 709. Published online 2023 Oct 31. doi: 10.1038/s41419-023-06235-8
PMCID:
PMC10616178
AbstractArticlePDF–9.4M
4.
OTUB1 promotes osteoblastic bone formation through stabilizing FGFR2
Qiong Zhu, Yesheng Fu, Chun-Ping Cui, Yi Ding, Zhikang Deng, Chao Ning, Fan Hu, Chen Qiu, Biyue Yu, Xuemei Zhou, Guan Yang, Jiang Peng, Weiguo Zou, Cui Hua Liu, Lingqiang Zhang
Signal Transduct Target Ther. 2023; 8: 142. Published online 2023 Apr 7. doi: 10.1038/s41392-023-01354-2
PMCID:
PMC10079838
AbstractArticlePDF–5.3M
5.
Smurf1 regulates ameloblast polarization by ubiquitination‐mediated degradation of RhoA
Haoman Niu, Fei Bi, Wenjun Zhao, Yuchan Xu, Qi Han, Weihua Guo, Yu Chen
Cell Prolif. 2023 Apr; 56(4): e13387. Published online 2022 Dec 29. doi: 10.1111/cpr.13387
PMCID:
PMC10068949
AbstractArticlePDF–4.7M
6.
Transmembrane anterior posterior transformation 1 regulates BMP signaling and modulates the protein stability of SMAD1/5
Bo Wang, Qian Zhao, Xiaoxia Gong, Caixia Wang, Yan Bai, Hongying Wang, Jianfeng Zhou, Xiaozhi Rong
J Biol Chem. 2022 Dec; 298(12): 102684. Published online 2022 Nov 9. doi: 10.1016/j.jbc.2022.102684
Correction in:
J Biol Chem. 2023 Jul; 299(7): 104957.
PMCID:
PMC9763856
AbstractArticlePDF–4.2M
7.
Long noncoding RNA SNHG1 silencing accelerates hepatocyte-like cell differentiation of bone marrow-derived mesenchymal stem cells to alleviate cirrhosis via the microRNA-15a/SMURF1/UVRAG axis
Jia Sun, Xuedong Sun, Sean Hu, Maoqiang Wang, Na Ma, Junhui Chen, Feng Duan
Cell Death Discov. 2022; 8: 77. Published online 2022 Feb 22. doi: 10.1038/s41420-022-00850-8
PMCID:
PMC8863836
AbstractArticlePDF–2.3M
8.
Neddylation modification of the U3 snoRNA-binding protein RRP9 by Smurf1 promotes tumorigenesis
Meng-ge Du, Fan Liu, Yan Chang, Shuai Tong, Wei Liu, Yu-jiao Chen, Ping Xie
J Biol Chem. 2021 Nov; 297(5): 101307. Published online 2021 Oct 15. doi: 10.1016/j.jbc.2021.101307
Correction in:
J Biol Chem. 2022 Nov; 298(11): 102567.
PMCID:
PMC8569593
AbstractArticlePDF–4.2M
9.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
10.
Mir379 Regulates Klotho Deficiency-induced cardiomyocyte Apoptosis via Repression of Smurf1
Kai Chen, Bo Zhang, Zhongjie Sun
Hypertension. Author manuscript; available in PMC 2022 Aug 1.
Published in final edited form as: Hypertension. 2021 Aug; 78(2): 342–352. Published online 2021 Jun 14. doi: 10.1161/HYPERTENSIONAHA.120.16888
PMCID:
PMC8285029
AbstractArticlePDF–1.4M
11.
Ubiquitination of UVRAG by SMURF1 promotes autophagosome maturation and inhibits hepatocellular carcinoma growth
Xing Feng, Yanyan Jia, Yuyu Zhang, Fei Ma, Yuekun Zhu, Xuehui Hong, Qingxin Zhou, Ruixing He, Heng Zhang, Junfei Jin, Daxun Piao, He Huang, Qinghua Li, Xingfeng Qiu, Zhiyong Zhang
Autophagy. 2019; 15(7): 1130–1149. Published online 2019 Jan 27. doi: 10.1080/15548627.2019.1570063
PMCID:
PMC6613838
AbstractArticlePDF–10M
12.
Non-proteolytic ubiquitin modification of PPARγ by Smurf1 protects the liver from steatosis
Kun Zhu, Yi Tang, Xuan Xu, Hien Dang, Liu-Ya Tang, Xiang Wang, Xin Wei Wang, Ying E. Zhang
PLoS Biol. 2018 Dec; 16(12): e3000091. Published online 2018 Dec 19. doi: 10.1371/journal.pbio.3000091
PMCID:
PMC6317813
AbstractArticlePDF–4.6M
13.
Inhibition of osteoblastic Smurf1 promotes bone formation in mouse models of distinctive age-related osteoporosis
Chao Liang, Songlin Peng, Jie Li, Jun Lu, Daogang Guan, Feng Jiang, Cheng Lu, Fangfei Li, Xiaojuan He, Hailong Zhu, D. W. T. Au, Dazhi Yang, Bao-Ting Zhang, Aiping Lu, Ge Zhang
Nat Commun. 2018; 9: 3428. Published online 2018 Aug 24. doi: 10.1038/s41467-018-05974-z
PMCID:
PMC6109183
AbstractArticlePDF–2.2M
14.
The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development
K. Koefoed, J. Skat-Rørdam, P. Andersen, C. B. Warzecha, M. Pye, T. A. Andersen, K. D. Ajbro, E. Bendsen, M. Narimatsu, F. Vilhardt, L. B. Pedersen, J. L. Wrana, R. H. Anderson, K. Møllgård, S. T. Christensen, L. A. Larsen
Sci Rep. 2018; 8: 9542. Published online 2018 Jun 22. doi: 10.1038/s41598-018-27854-8
PMCID:
PMC6015040
AbstractArticlePDF–6.3M
15.
The ubiquitin-ligase Smurf1 functions in selective autophagy of M. tuberculosis and anti-tuberculous host defense
Luis H. Franco, Vidhya R. Nair, Caitlyn R. Scharn, Ramnik J. Xavier, Jose R. Torrealba, Michael U. Shiloh, Beth Levine
Cell Host Microbe. Author manuscript; available in PMC 2018 Jan 11.
Published in final edited form as: Cell Host Microbe. 2017 Jan 11; 21(1): 59–72. Published online 2016 Dec 22. doi: 10.1016/j.chom.2016.11.002
Correction in:
Cell Host Microbe. 2017 Sep 13; 22(3): 421–423.
PMCID:
PMC5699477
AbstractArticlePDF–1.2M
16.
Smurf1 inhibits integrin activation by controlling Kindlin-2 ubiquitination and degradation
Xiaofan Wei, Xiang Wang, Jun Zhan, Yuhan Chen, Weigang Fang, Lingqiang Zhang, Hongquan Zhang
J Cell Biol. 2017 May 1; 216(5): 1455–1471. doi: 10.1083/jcb.201609073
PMCID:
PMC5412569
AbstractArticlePDF–3.1M
17.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
18.
Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2
Yoshinori Matsumoto, Jose La Rose, Oliver A. Kent, Melany J. Wagner, Masahiro Narimatsu, Aaron D. Levy, Mitchell H. Omar, Jiefei Tong, Jonathan R. Krieger, Emily Riggs, Yaryna Storozhuk, Julia Pasquale, Manuela Ventura, Behzad Yeganeh, Martin Post, Michael F. Moran, Marc D. Grynpas, Jeffrey L. Wrana, Giulio Superti-Furga, Anthony J. Koleske, Ann Marie Pendergast, Robert Rottapel
J Clin Invest. 2016 Dec 1; 126(12): 4482–4496. Published online 2016 Oct 31. doi: 10.1172/JCI87802
PMCID:
PMC5127668
AbstractArticlePDF–4.6M
19.
BMPER regulates cardiomyocyte size and vessel density in vivo
Monte S. Willis, Laura A. Dyer, Rongqin Ren, Pamela Lockyer, Isabel Moreno-Miralles, Jonathan C. Schisler, Cam Patterson
Cardiovasc Pathol. Author manuscript; available in PMC 2016 Sep 19.
Published in final edited form as: Cardiovasc Pathol. 2013 May-Jun; 22(3): 228–240. Published online 2012 Nov 28. doi: 10.1016/j.carpath.2012.10.005
PMCID:
PMC5027882
AbstractArticlePDF–1.3M
20.
MicroRNA-140-5p and SMURF1 regulate pulmonary arterial hypertension
Alexander M.K. Rothman, Nadine D. Arnold, Josephine A. Pickworth, James Iremonger, Loredana Ciuclan, Robert M.H. Allen, Sabine Guth-Gundel, Mark Southwood, Nicholas W. Morrell, Matthew Thomas, Sheila E. Francis, David J. Rowlands, Allan Lawrie
J Clin Invest. 2016 Jul 1; 126(7): 2495–2508. Published online 2016 May 23. doi: 10.1172/JCI83361
PMCID:
PMC4922709
AbstractArticlePDF–2.7M

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