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Select item 109315421.

Cathelicidin Antimicrobial Peptide Levels in Atherosclerosis and Myocardial Infarction in Mice and Human

Alexandra Höpfinger, Andreas Schmid, Thomas Karrasch, Sabine Pankuweit, Andreas Schäffler, Karsten Grote

Int J Mol Sci. 2024 Mar; 25(5): 2909. Published online 2024 Mar 2. doi: 10.3390/ijms25052909

PMCID:: PMC10931542

Abstract Article PDF–2.0M

Select item 109040432.

Increased LL37 in psoriasis and other inflammatory disorders promotes LDL uptake and atherosclerosis

Yoshiyuki Nakamura, Nikhil N. Kulkarni, Toshiya Takahashi, Haleh Alimohamadi, Tatsuya Dokoshi, Edward Liu, Michael Shia, Tomofumi Numata, Elizabeth W.C. Luo, Adrian F. Gombart, Xiaohong Yang, Patrick Secrest, Philip L.S.M. Gordts, Sotirios Tsimikas, Gerard C.L. Wong, Richard L. Gallo

J Clin Invest. 2024 Mar 1; 134(5): e172578. Published online 2024 Mar 1. doi: 10.1172/JCI172578

PMCID:: PMC10904043

Abstract Article PDF–1.9M

Select item 103039203.

Competition between skin antimicrobial peptides and commensal bacteria in type 2 inflammation enables survival of S. aureus

Teruaki Nakatsuji, Samantha L. Brinton, Kellen J. Cavagnero, Alan M. O’Neill, Yang Chen, Tatsuya Dokoshi, Anna M. Butcher, Olive C. Osuoji, Faiza Shafiq, Josh L. Espinoza, Christopher L. Dupont, Tissa R. Hata, Richard L. Gallo

Cell Rep. Author manuscript; available in PMC 2023 Jun 28.

Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112494. Published online 2023 May 10. doi: 10.1016/j.celrep.2023.112494

PMCID:: PMC10303920

Abstract Article PDF–2.5M

Select item 100621714.

Cathelicidins Target HSP60 To Restrict CVB3 Transmission via Disrupting the Exosome and Reducing Cardiomyocyte Apoptosis

Yang Yang, Chunjing Huang, Li Hui, Yahui Song, Yuxuan Fu, Min Li, Hailong Yang, Jing Wu, Jia Sun, Wei Xu, Lin Wei

J Virol. 2023 Mar; 97(3): e01433-22. Published online 2023 Mar 14. doi: 10.1128/jvi.01433-22

PMCID:: PMC10062171

Abstract Article PDF–5.3M

Select item 94558635.

The antimicrobial peptide cathelicidin drives development of experimental autoimmune encephalomyelitis in mice by affecting Th17 differentiation

Katie J. Smith, Danielle Minns, Brian J. McHugh, Rebecca K. Holloway, Richard O’Connor, Anna Williams, Lauren Melrose, Rhoanne McPherson, Veronique E. Miron, Donald J. Davidson, Emily Gwyer Findlay

PLoS Biol. 2022 Aug; 20(8): e3001554. Published online 2022 Aug 26. doi: 10.1371/journal.pbio.3001554

PMCID:: PMC9455863

Abstract Article PDF–2.5M

Select item 91232946.

Role of LL-37 in thrombotic complications in patients with COVID-19

Zilei Duan, Juan Zhang, Xue Chen, Ming Liu, Hongwen Zhao, Lin Jin, Zhiye Zhang, Ning Luan, Ping Meng, Jing Wang, Zhaoxia Tan, Yaxiong Li, Guohong Deng, Ren Lai

Cell Mol Life Sci. 2022 Jun; 79(6): 309. Published online 2022 May 21. doi: 10.1007/s00018-022-04309-y

PMCID:: PMC9123294

Abstract Article PDF–3.6M

Select item 86992087.

Deficiency of Cathelicidin Attenuates High-Fat Diet Plus Alcohol-Induced Liver Injury through FGF21/Adiponectin Regulation

Fengyuan Li, Jenny Chen, Yunhuan Liu, Zelin Gu, Mengwei Jiang, Lihua Zhang, Shao-Yu Chen, Zhongbin Deng, Craig J. McClain, Wenke Feng

Cells. 2021 Dec; 10(12): 3333. Published online 2021 Nov 27. doi: 10.3390/cells10123333

PMCID:: PMC8699208

Abstract Article PDF–31M

Select item 86783138.

Adoptive cell therapy with tumor-specific Th9 cells induces viral mimicry to eliminate antigen-loss-variant tumor cells

Gang Xue, Ningbo Zheng, Jing Fang, Guangxu Jin, Xiaoyin Li, Gianpietro Dotti, Qing Yi, Yong Lu

Cancer Cell. Author manuscript; available in PMC 2022 Dec 13.

Published in final edited form as: Cancer Cell. 2021 Dec 13; 39(12): 1610–1622.e9. Published online 2021 Oct 21. doi: 10.1016/j.ccell.2021.09.011

PMCID:: PMC8678313

Abstract Article PDF–2.1M

Select item 83509019.

Gut microbiota‐CRAMP axis shapes intestinal barrier function and immune responses in dietary gluten‐induced enteropathy

Zhengnan Ren, Li‐Long Pan, Yiwen Huang, Hongbing Chen, Yu Liu, He Liu, Xing Tu, Yanyan Liu, Binbin Li, Xiaoliang Dong, Xiaohua Pan, Hanfei Li, Yu V Fu, Birgitta Agerberth, Julien Diana, Jia Sun

EMBO Mol Med. 2021 Aug 9; 13(8): e14059. Published online 2021 Jun 14. doi: 10.15252/emmm.202114059

PMCID:: PMC8350901

Abstract Article PDF–6.1M

Select item 810310510.

A positive feedback loop between mTORC1 and cathelicidin promotes skin inflammation in rosacea

Zhili Deng, Mengting Chen, Yingzi Liu, San Xu, Yuyan Ouyang, Wei Shi, Dan Jian, Ben Wang, Fangfen Liu, Jinmao Li, Qian Shi, Qinqin Peng, Ke Sha, Wenqin Xiao, Tangxiele Liu, Yiya Zhang, Hongbing Zhang, Qian Wang, Lunquan Sun, Hongfu Xie, Ji Li

EMBO Mol Med. 2021 May 7; 13(5): e13560. Published online 2021 Mar 18. doi: 10.15252/emmm.202013560

PMCID:: PMC8103105

Abstract Article PDF–7.7M

Select item 800621711.

Fengyuan Li, Cuiqing Zhao, Tuo Shao, Yunhuan Liu, Zelin Gu, Mengwei Jiang, Huimin Li, Lihua Zhang, Patrick M Gillevet, Puneet Puri, Zhong-Bin Deng, Shao-Yu Chen, Shirish Barve, Leila Gobejishvili, Vatsalya Vatsalya, Craig J McClain, Wenke Feng

J Pathol. Author manuscript; available in PMC 2021 Mar 29.

Published in final edited form as: J Pathol. 2020 Dec; 252(4): 371–383. Published online 2020 Sep 26. doi: 10.1002/path.5531

PMCID:: PMC8006217

Abstract Article PDF–3.1M

Select item 789838612.

Distinct contributions of cathelin‐related antimicrobial peptide (CRAMP) derived from epithelial cells and macrophages to colon mucosal homeostasis

Keqiang Chen, Teizo Yoshimura, Xiaohong Yao, Wanghua Gong, Jiaqiang Huang, Amiran K Dzutsev, John McCulloch, Colm O'hUigin, Xiu‐wu Bian, Giorgio Trinchieri, Ji Ming Wang

J Pathol. 2021 Mar; 253(3): 339–350. Published online 2021 Jan 19. doi: 10.1002/path.5572

PMCID:: PMC7898386

Abstract Article PDF–29M

Select item 780718013.

Cathelicidin protects mice from Rhabdomyolysis-induced Acute Kidney Injury

Beatriz Helena Cermaria Soares da Silva, Suely Kubo Ariga, Hermes Vieira Barbeiro, Rildo Aparecido Volpini, Denise Frediani Barbeiro, Antonio Carlos Seguro, Fabiano Pinheiro da Silva

Int J Med Sci. 2021; 18(4): 883–890. Published online 2021 Jan 1. doi: 10.7150/ijms.52397

PMCID:: PMC7807180

Abstract Article PDF–1.0M

Select item 757356914.

The Role of T Cells Reactive to the Cathelicidin Antimicrobial Peptide LL-37 in Acute Coronary Syndrome and Plaque Calcification

Fernando Chernomordik, Bojan Cercek, Wai Man Lio, Peter M. Mihailovic, Juliana Yano, Romana Herscovici, Xiaoning Zhao, Jianchang Zhou, Kuang-Yuh Chyu, Prediman K. Shah, Paul C. Dimayuga

Front Immunol. 2020; 11: 575577. Published online 2020 Oct 6. doi: 10.3389/fimmu.2020.575577

PMCID:: PMC7573569

Abstract Article PDF–4.4M

Select item 755242715.

Efficacy of Antigonococcal CMP-Nonulosonate Therapeutics Require Cathelicidins

Sunita Gulati, Ian C Schoenhofen, Theresa Lindhout-Djukic, Lisa A Lewis, Iesha Y Moustafa, Sudeshna Saha, Bo Zheng, Nancy Nowak, Peter A Rice, Ajit Varki, Sanjay Ram

J Infect Dis. 2020 Nov 15; 222(10): 1641–1650. Published online 2020 Jul 21. doi: 10.1093/infdis/jiaa438

PMCID:: PMC7552427

Abstract Article PDF–3.9M

Select item 752437216.

Cathelicidin-mediated lipopolysaccharide signaling via intracellular TLR4 in colonic epithelial cells evokes CXCL8 production

Ravi Holani, Anshu Babbar, Graham A. D. Blyth, Fernando Lopes, Humberto Jijon, Derek M. McKay, Morley D. Hollenberg, Eduardo R. Cobo

Gut Microbes. 2020; 12(1): 1785802. Published online 2020 Jul 13. doi: 10.1080/19490976.2020.1785802

PMCID:: PMC7524372

Abstract Article PDF–6.4M

Select item 743946117.

Chlamydia trachomatis Plasmid Gene Protein 3 Is Essential for the Establishment of Persistent Infection and Associated Immunopathology

Chunfu Yang, Laszlo Kari, Lei Lei, John H. Carlson, Li Ma, Claire E. Couch, William M. Whitmire, Kevin Bock, Ian Moore, Christine Bonner, Grant McClarty, Harlan D. Caldwell

mBio. 2020 Jul-Aug; 11(4): e01902-20. Published online 2020 Aug 18. doi: 10.1128/mBio.01902-20

PMCID:: PMC7439461

Abstract Article PDF–2.7M

Select item 723607718.

Li‐Long Pan, Wenjie Liang, Zhengnan Ren, Chunqing Li, Yong Chen, Wenying Niu, Xin Fang, Yanyan Liu, Ming Zhang, Julien Diana, Birgitta Agerberth, Jia Sun

Br J Pharmacol. 2020 Jun; 177(12): 2726–2742. Published online 2020 Feb 12. doi: 10.1111/bph.14998

PMCID:: PMC7236077

Abstract Article PDF–11M

Select item 719199719.

Ling-juan Zhang, Stella Xiang Chen, Christian F. Guerrero-Juarez, Fengwu Li, Yun Tong, Yuqiong Liang, Marc Liggins, Xu Chen, Hao Chen, Min Li, Tissa Hata, Ye Zheng, Maksim V. Plikus, Richard L. Gallo

Immunity. Author manuscript; available in PMC 2020 Apr 30.

Published in final edited form as: Immunity. 2019 Jan 15; 50(1): 121–136.e5. Published online 2018 Dec 26. doi: 10.1016/j.immuni.2018.11.003

PMCID:: PMC7191997

Abstract Article PDF–4.6M

Select item 717855320.

Host Cathelicidin Exacerbates Group B Streptococcus Urinary Tract Infection

Kathryn A. Patras, Alison Coady, Priyanka Babu, Samuel R. Shing, Albert D. Ha, Emma Rooholfada, Stephanie L. Brandt, Matthew Geriak, Richard L. Gallo, Victor Nizet

mSphere. 2020 Mar-Apr; 5(2): e00932-19. Published online 2020 Apr 22. doi: 10.1128/mSphere.00932-19