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Select item 113624591.

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation

Lisa Kofler, Lorenz Grundmann, Magdalena Gerhalter, Michael Prattes, Juliane Merl-Pham, Gertrude Zisser, Irina Grishkovskaya, Victor-Valentin Hodirnau, Martin Vareka, Rolf Breinbauer, Stefanie M. Hauck, David Haselbach, Helmut Bergler

Nat Commun. 2024; 15: 7511. Published online 2024 Aug 29. doi: 10.1038/s41467-024-51754-3

PMCID:: PMC11362459

Abstract Article PDF–3.5M

Select item 110241852.

The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis

Victor E. Cruz, Christine S. Weirich, Nagesh Peddada, Jan P. Erzberger

Nat Commun. 2024; 15: 3296. Published online 2024 Apr 17. doi: 10.1038/s41467-024-47616-7

PMCID:: PMC11024185

Abstract Article PDF–7.4M

Select item 108724773.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 108687274.

Adaptive preservation of orphan ribosomal proteins in chaperone-dispersed condensates

Asif Ali, Rania Garde, Olivia C. Schaffer, Jared A. M. Bard, Kabir Husain, Samantha Keyport Kik, Kathleen A. Davis, Sofia Luengo-Woods, Maya G. Igarashi, D. Allan Drummond, Allison H. Squires, David Pincus

Nat Cell Biol. Author manuscript; available in PMC 2024 Feb 15.

Published in final edited form as: Nat Cell Biol. 2023 Nov; 25(11): 1691–1703. Published online 2023 Oct 16. doi: 10.1038/s41556-023-01253-2

PMCID:: PMC10868727

Abstract Article PDF–7.0M

Select item 107988585.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107116656.

The ribosome‐associated chaperone Zuo1 controls translation upon TORC1 inhibition

Ailsa Black, Thomas D Williams, Flavie Soubigou, Ifeoluwapo M Joshua, Houjiang Zhou, Frederic Lamoliatte, Adrien Rousseau

EMBO J. 2023 Dec; 42(24): e113240. Published online 2023 Nov 20. doi: 10.15252/embj.2022113240

PMCID:: PMC10711665

Abstract Article PDF–4.0M

Select item 107001387.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105211378.

Checkpoint kinase interaction with DNA polymerase alpha regulates replication progression during stress

Andreas Hadjicharalambous, Alex J. Whale, Geylani Can, J. Mark Skehel, Jonathan M. Houseley, Philip Zegerman

Version 1. Wellcome Open Res. 2023; 8: 327. Published online 2023 Jul 26. doi: 10.12688/wellcomeopenres.19617.1

PMCID:: PMC10521137

Abstract Article PDF–4.0M

Select item 102478119.

The GET pathway is a major bottleneck for maintaining proteostasis in Saccharomyces cerevisiae

Rebecca Josefson, Navinder Kumar, Xinxin Hao, Beidong Liu, Thomas Nyström

Sci Rep. 2023; 13: 9285. Published online 2023 Jun 7. doi: 10.1038/s41598-023-35666-8

PMCID:: PMC10247811

Abstract Article PDF–8.1M

Select item 1023508610.

Rio1 downregulates centromeric RNA levels to promote the timely assembly of structurally fit kinetochores

Ksenia Smurova, Michela Damizia, Carmela Irene, Stefania Stancari, Giovanna Berto, Giulia Perticari, Maria Giuseppina Iacovella, Ilaria D’Ambrosio, Maria Giubettini, Réginald Philippe, Chiara Baggio, Elisabetta Callegaro, Andrea Casagranda, Alessandro Corsini, Vincenzo Gentile Polese, Anna Ricci, Erik Dassi, Peter De Wulf

Nat Commun. 2023; 14: 3172. Published online 2023 Jun 1. doi: 10.1038/s41467-023-38920-9

PMCID:: PMC10235086

Abstract Article PDF–2.6M

Select item 963802811.

Yeast Smy2 and its human homologs GIGYF1 and -2 regulate Cdc48/VCP function during transcription stress

Michelle Harreman Lehner, Jane Walker, Kotryna Temcinaite, Anna Herlihy, Michael Taschner, Adam C. Berger, Anita H. Corbett, A. Barbara Dirac Svejstrup, Jesper Q. Svejstrup

Cell Rep. 2022 Oct 25; 41(4): 111536. Published online 2022 Oct 25. doi: 10.1016/j.celrep.2022.111536

PMCID:: PMC9638028

Abstract Article

Select item 920981112.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 880492913.

Oxidative stress protein Oxr1 promotes V‐ATPase holoenzyme disassembly in catalytic activity‐independent manner

Md. Murad Khan, Seowon Lee, Sergio Couoh‐Cardel, Rebecca A Oot, Hyunmin Kim, Stephan Wilkens, Soung‐Hun Roh

EMBO J. 2022 Feb 1; 41(3): e109360. Published online 2021 Dec 17. doi: 10.15252/embj.2021109360

PMCID:: PMC8804929

Abstract Article PDF–5.5M

Select item 857106314.

Systems-level effects of allosteric perturbations to a model molecular switch

Tina Perica, Christopher J. P. Mathy, Jiewei Xu, Gwendolyn M. Jang, Yang Zhang, Robyn Kaake, Noah Ollikainen, Hannes Braberg, Danielle L. Swaney, David G. Lambright, Mark J. S. Kelly, Nevan J. Krogan, Tanja Kortemme

Nature. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Nature. 2021 Nov; 599(7883): 152–157. Published online 2021 Oct 13. doi: 10.1038/s41586-021-03982-6

PMCID:: PMC8571063

Abstract Article PDF–2.7M

Select item 802272515.

ASNS disruption shortens CTPS cytoophidia in Saccharomyces cerevisiae

Shanshan Zhang, Han-Chao Feng, Ji-Long Liu

G3 (Bethesda) 2021 Jan; 11(1): jkaa060. Published online 2021 Jan 11. doi: 10.1093/g3journal/jkaa060

PMCID:: PMC8022725

Abstract Article PDF–955K

Select item 794844816.

14-3-3 Protein Bmh1 triggers short-range compaction of mitotic chromosomes by recruiting sirtuin deacetylase Hst2

Neha Jain, Petra Janning, Heinz Neumann

J Biol Chem. 2021 Jan-Jun; 296: 100078. Published online 2020 Nov 23. doi: 10.1074/jbc.AC120.014758

PMCID:: PMC7948448

Abstract Article PDF–1.3M

Select item 775888017.

Purified Smc5/6 Complex Exhibits DNA Substrate Recognition and Compaction

Pilar Gutierrez-Escribano, Silvia Hormeño, Julene Madariaga-Marcos, Roger Solé-Soler, Francis J. O’Reilly, Kyle Morris, Clara Aicart-Ramos, Ricardo Aramayo, Alex Montoya, Holger Kramer, Juri Rappsilber, Jordi Torres-Rosell, Fernando Moreno-Herrero, Luis Aragon

Mol Cell. 2020 Dec 17; 80(6): 1039–1054.e6. doi: 10.1016/j.molcel.2020.11.012