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Items: 1 to 20 of 28

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins
Mickaële Hémono, Alexandre Haller, Johana Chicher, Anne-Marie Duchêne, Richard Patryk Ngondo
BMC Biol. 2022; 20: 13. Published online 2022 Jan 10. doi: 10.1186/s12915-021-01213-y
PMCID:
PMC8744257
AbstractArticlePDF–6.0M
3.
Single-cell architecture and functional requirement of alternative splicing during hematopoietic stem cell formation
Fang Wang, Puwen Tan, Pengcheng Zhang, Yue Ren, Jie Zhou, Yunqiao Li, Siyuan Hou, Shuaili Li, Linlin Zhang, Yanni Ma, Chaojie Wang, Wanbo Tang, Xiaoshuang Wang, Yue Huo, Yongfei Hu, Tianyu Cui, Chao Niu, Dong Wang, Bing Liu, Yu Lan, Jia Yu
Sci Adv. 2022 Jan; 8(1): eabg5369. Published online 2022 Jan 7. doi: 10.1126/sciadv.abg5369
PMCID:
PMC8741192
AbstractArticlePDF–4.0M
4.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
5.
STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells
Lin Jin, Yunjia Chen, David K. Crossman, Arunima Datta, Trung Vu, James A. Mobley, Malay Kumar Basu, Mariangela Scarduzio, Hengbin Wang, Chenbei Chang, Pran K. Datta
Nat Commun. 2020; 11: 5941. Published online 2020 Nov 23. doi: 10.1038/s41467-020-19698-6
PMCID:
PMC7684319
AbstractArticlePDF–3.4M
6.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
7.
N-Terminus of the Protein Kinase CLK1 Induces SR Protein Hyper-Phosphorylation
Brandon E. Aubol, Ryan M. Plocinik, Malik M. Keshwani, Maria L. McGlone, Jonathan C. Hagopian, Gourisankar Ghosh, Xiang-Dong Fu, Joseph A. Adams
Biochem J. Author manuscript; available in PMC 2016 Oct 10.
Published in final edited form as: Biochem J. 2014 Aug 15; 462(1): 143–152. doi: 10.1042/BJ20140494
PMCID:
PMC5056641
AbstractArticlePDF–1.5M
8.
A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs
Alexander Karlas, Stefano Berre, Thérèse Couderc, Margus Varjak, Peter Braun, Michael Meyer, Nicolas Gangneux, Liis Karo-Astover, Friderike Weege, Martin Raftery, Günther Schönrich, Uwe Klemm, Anne Wurzlbauer, Franz Bracher, Andres Merits, Thomas F. Meyer, Marc Lecuit
Nat Commun. 2016; 7: 11320. Published online 2016 May 12. doi: 10.1038/ncomms11320
PMCID:
PMC4865845
AbstractArticlePDF–2.4M
9.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
10.
Clk/STY (cdc2-Like Kinase 1) and Akt Regulate Alternative Splicing and Adipogenesis in 3T3-L1 Pre-Adipocytes
Pengfei Li, Gay Carter, Jacqueline Romero, Kathryn M. Gower, James Watson, Niketa A. Patel, Denise R. Cooper
PLoS One. 2013; 8(1): e53268. Published online 2013 Jan 4. doi: 10.1371/journal.pone.0053268
PMCID:
PMC3537621
AbstractArticlePDF–1.2M
11.
Stress-responsive maturation of Clk1/4 pre-mRNAs promotes phosphorylation of SR splicing factor
Kensuke Ninomiya, Naoyuki Kataoka, Masatoshi Hagiwara
J Cell Biol. 2011 Oct 3; 195(1): 27–40. doi: 10.1083/jcb.201107093
PMCID:
PMC3187705
AbstractArticlePDF–3.0M
12.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
13.
The Aging-Associated Enzyme CLK-1 is a Member of the Carboxylate-Bridged Diiron Family of Proteins
Rachel K. Behan, Stephen J. Lippard
Biochemistry. Author manuscript; available in PMC 2011 Nov 16.
Published in final edited form as: Biochemistry. 2010 Nov 16; 49(45): 9679–9681. Published online 2010 Oct 21. doi: 10.1021/bi101475z
PMCID:
PMC2976817
AbstractArticlePDF–1.0M
14.
Akt2 Regulation of Cdc2-Like Kinases (Clk/Sty), Serine/Arginine-Rich (SR) Protein Phosphorylation, and Insulin-Induced Alternative Splicing of PKCβII Messenger Ribonucleic Acid
Kun Jiang, Niketa A. Patel, James E. Watson, Hercules Apostolatos, Eden Kleiman, Olivia Hanson, Masatoshi Hagiwara, Denise R. Cooper
Endocrinology. 2009 May; 150(5): 2087–2097. Published online 2008 Dec 30. doi: 10.1210/en.2008-0818
PMCID:
PMC2671910
AbstractArticle
15.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
16.
Characterization and comparison of four serine- and arginine-rich (SR) protein kinases.
O Nayler, S Stamm, A Ullrich
Biochem J. 1997 Sep 15; 326(Pt 3): 693–700. doi: 10.1042/bj3260693
PMCID:
PMC1218723
SummaryPDF–582K
17.
A mammalian protein kinase with potential for serine/threonine and tyrosine phosphorylation is related to cell cycle regulators.
Y Ben-David, K Letwin, L Tannock, A Bernstein, T Pawson
EMBO J. 1991 Feb; 10(2): 317–325. doi: 10.1002/j.1460-2075.1991.tb07952.x
PMCID:
PMC452648
SummaryPage BrowsePDF–1.9M
18.
The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution.
K Colwill, T Pawson, B Andrews, J Prasad, J L Manley, J C Bell, P I Duncan
EMBO J. 1996 Jan 15; 15(2): 265–275.
PMCID:
PMC449941
SummaryPage BrowsePDF–2.5M
19.
Genomic Analysis of Mouse Retinal Development
Seth Blackshaw, Sanjiv Harpavat, Jeff Trimarchi, Li Cai, Haiyan Huang, Winston P Kuo, Griffin Weber, Kyungjoon Lee, Rebecca E Fraioli, Seo-Hee Cho, Rachel Yung, Elizabeth Asch, Lucila Ohno-Machado, Wing H Wong, Constance L Cepko
PLoS Biol. 2004 Sep; 2(9): e247. Published online 2004 Jun 29. doi: 10.1371/journal.pbio.0020247
PMCID:
PMC439783
AbstractArticlePDF–975K
20.
Targeting a Complex Transcriptome: The Construction of the Mouse Full-Length cDNA Encyclopedia
Piero Carninci, Kazunori Waki, Toshiyuki Shiraki, Hideaki Konno, Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Takahiro Arakawa, Yoshiyuki Ishii, Daisuke Sasaki, Hidemasa Bono, Shinji Kondo, Yuichi Sugahara, Rintaro Saito, Naoki Osato, Shiro Fukuda, Kenjiro Sato, Akira Watahiki, Tomoko Hirozane-Kishikawa, Mari Nakamura, Yuko Shibata, Ayako Yasunishi, Noriko Kikuchi, Atsushi Yoshiki, Moriaki Kusakabe, Stefano Gustincich, Kirk Beisel, William Pavan, Vassilis Aidinis, Akira Nakagawara, William A. Held, Hiroo Iwata, Tomohiro Kono, Hiromitsu Nakauchi, Paul Lyons, Christine Wells, David A. Hume, Michela Fagiolini, Takao K. Hensch, Michelle Brinkmeier, Sally Camper, Junji Hirota, Peter Mombaerts, Masami Muramatsu, Yasushi Okazaki, Jun Kawai, Yoshihide Hayashizaki
Genome Res. 2003 Jun; 13(6b): 1273–1289. doi: 10.1101/gr.1119703
PMCID:
PMC403712
AbstractArticlePDF–770K

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