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Items: 1 to 20 of 26

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Loss of Ufl1/Ufbp1 in hepatocytes promotes liver pathological damage and carcinogenesis through activating mTOR signaling
Fanghui Chen, Le Sheng, Tianci Zhou, Li Yan, Reid Loveless, Honglin Li, Yong Teng, Yafei Cai
J Exp Clin Cancer Res. 2023; 42: 110. Published online 2023 May 3. doi: 10.1186/s13046-023-02681-6
PMCID:
PMC10155312
AbstractArticlePDF–5.2M
3.
Dysregulation of PD-L1 by UFMylation imparts tumor immune evasion and identified as a potential therapeutic target
Junzhi Zhou, Xiaohe Ma, Xingrui He, Beiying Chen, Jiao Yuan, Zhemin Jin, Lijing Li, Zhiguo Wang, Qian Xiao, Yafei Cai, Yongkang Zou
Proc Natl Acad Sci U S A. 2023 Mar 14; 120(11): e2215732120. Published online 2023 Mar 9. doi: 10.1073/pnas.2215732120
Correction in:
Proc Natl Acad Sci U S A. 2023 May 23; 120(21): e2306087120.
PMCID:
PMC10089188
AbstractArticlePDF–14M
4.
UFL1 promotes antiviral immune response by maintaining STING stability independent of UFMylation
Yijie Tao, Shulei Yin, Yang Liu, Chunzhen Li, Yining Chen, Dan Han, Jingyi Huang, Sheng Xu, Zui Zou, Yizhi Yu
Cell Death Differ. 2023 Jan; 30(1): 16–26. Published online 2022 Jul 23. doi: 10.1038/s41418-022-01041-9
PMCID:
PMC9883236
AbstractArticlePDF–4.0M
5.
Ufl1 deficiency causes skin pigmentation by up-regulation of Endothelin-1
Ke Wang, Hu-Ning Xu, Yi-Wen Wang, Jian Mao, Da Liu, Xiao-Jing Zhu, Yu-Sheng Cong, Miao Wang
Front Cell Dev Biol. 2022; 10: 961675. Published online 2022 Sep 2. doi: 10.3389/fcell.2022.961675
PMCID:
PMC9478483
AbstractArticlePDF–2.3M
6.
UFM1-Specific Ligase 1 Ligating Enzyme 1 Mediates Milk Protein and Fat Synthesis-Related Gene Expression via the JNK Signaling Pathway in Mouse Mammary Epithelial Cells
Meiqian Kuang, Min Yang, Lian Li, Chengmin Li, Genlin Wang
Oxid Med Cell Longev. 2020; 2020: 4045674. Published online 2020 Jun 19. doi: 10.1155/2020/4045674
PMCID:
PMC7321527
AbstractArticlePDF–1.9M
7.
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics
Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea
Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253
PMCID:
PMC6692770
AbstractArticlePDF–7.7M
8.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
9.
Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammation
Yafei Cai, Guangxun Zhu, Siyang Liu, Zezheng Pan, Michaela Quintero, Candace J. Poole, Chunwan Lu, Huabin Zhu, Bianca Islam, Jan van Riggelen, Darren Browning, Kebin Liu, Richard Blumberg, Nagendra Singh, Honglin Li
Cell Discov. 2019; 5: 7. Published online 2019 Jan 29. doi: 10.1038/s41421-018-0070-x
PMCID:
PMC6349939
AbstractArticlePDF–6.4M
10.
Plasticity in the Glucagon Interactome Reveals Novel Proteins That Regulate Glucagon Secretion in α-TC1-6 Cells
Farzad Asadi, Savita Dhanvantari
Front Endocrinol (Lausanne) 2018; 9: 792. Published online 2019 Jan 18. doi: 10.3389/fendo.2018.00792
PMCID:
PMC6346685
AbstractArticlePDF–3.6M
11.
The Ufm1-Specific Ligase Ufl1 Regulates Endoplasmic Reticulum Homeostasis and Protects against Heart Failure
Jie Li, Guihua Yue, Wenxia Ma, Aizhen Zhang, Jianqiu Zou, Yafei Cai, Xiaoli Tang, Jun Wang, Jinbao Liu, Honglin Li, Huabo Su
Circ Heart Fail. Author manuscript; available in PMC 2019 Oct 1.
Published in final edited form as: Circ Heart Fail. 2018 Oct; 11(10): e004917. doi: 10.1161/CIRCHEARTFAILURE.118.004917
PMCID:
PMC6205741
AbstractArticlePDF–1.7M
12.
RCAD/Ufl1, a Ufm1 E3 ligase, is essential for hematopoietic stem cell function and murine hematopoiesis
M Zhang, X Zhu, Y Zhang, Y Cai, J Chen, S Sivaprakasam, A Gurav, W Pi, L Makala, J Wu, B Pace, D Tuan-Lo, V Ganapathy, N Singh, H Li
Cell Death Differ. 2015 Dec; 22(12): 1922–1934. Published online 2015 May 8. doi: 10.1038/cdd.2015.51
PMCID:
PMC4816109
AbstractArticlePDF–4.4M
13.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
14.
Transcriptional Regulation of the Ufm1 Conjugation System in Response to Disturbance of the Endoplasmic Reticulum Homeostasis and Inhibition of Vesicle Trafficking
Yinghua Zhang, Mingsheng Zhang, Jianchun Wu, Guohua Lei, Honglin Li
PLoS One. 2012; 7(11): e48587. Published online 2012 Nov 13. doi: 10.1371/journal.pone.0048587
PMCID:
PMC3496721
AbstractArticlePDF–963K
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
Ubiquitin Fold Modifier 1 (UFM1) and Its Target UFBP1 Protect Pancreatic Beta Cells from ER Stress-Induced Apoptosis
Katleen Lemaire, Rodrigo F. Moura, Mikaela Granvik, Mariana Igoillo-Esteve, Hans E. Hohmeier, Nico Hendrickx, Christopher B. Newgard, Etienne Waelkens, Miriam Cnop, Frans Schuit
PLoS One. 2011; 6(4): e18517. Published online 2011 Apr 6. doi: 10.1371/journal.pone.0018517
PMCID:
PMC3071830
AbstractArticlePDF–955K
17.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
18.
Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity
Hiroki Shiwaku, Natsue Yoshimura, Takuya Tamura, Masaki Sone, Soichi Ogishima, Kei Watase, Kazuhiko Tagawa, Hitoshi Okazawa
EMBO J. 2010 Jul 21; 29(14): 2446–2460. Published online 2010 Jun 8. doi: 10.1038/emboj.2010.116
PMCID:
PMC2910266
AbstractArticlePDF–4.6M
19.
Mitochondrial Phosphoproteome Revealed by an Improved IMAC Method and MS/MS/MS
Jaeick Lee, Yingda Xu, Yue Chen, Robert Sprung, Sung Chan Kim, Shanhai Xie, Yingming Zhao
Mol Cell Proteomics. Author manuscript; available in PMC 2010 Jul 13.
Published in final edited form as: Mol Cell Proteomics. 2007 Apr; 6(4): 669–676. Published online 2007 Jan 5. doi: 10.1074/mcp.M600218-MCP200
PMCID:
PMC2902983
AbstractArticlePDF–392K
20.
A Novel C53/LZAP-interacting Protein Regulates Stability of C53/LZAP and DDRGK Domain-containing Protein 1 (DDRGK1) and Modulates NF-κB Signaling
Jianchun Wu, Guohua Lei, Mei Mei, Yi Tang, Honglin Li
J Biol Chem. 2010 May 14; 285(20): 15126–15136. Published online 2010 Mar 12. doi: 10.1074/jbc.M110.110619
PMCID:
PMC2865345
AbstractArticlePDF–3.0M

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