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Select item 103302991.

Ubiquitin ligases Siah1a/2 control alveolar macrophage functions to limit carcinogen-induced lung adenocarcinoma

Marzia Scortegagna, Yuanning Du, Linda M. Bradley, Kun Wang, Alfredo Molinolo, Eytan Ruppin, Rabi Murad, Ze’ev A. Ronai

Cancer Res. Author manuscript; available in PMC 2023 Dec 15.

Published in final edited form as: Cancer Res. 2023 Jun 15; 83(12): 2016–2033. doi: 10.1158/0008-5472.CAN-23-0258

PMCID:: PMC10330299

Abstract Article PDF–2.6M

Select item 57522722.

The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion

Marzia Scortegagna, Annabel Berthon, Nikolaos Settas, Andreas Giannakou, Guillermina Garcia, Jian-Liang Li, Brian James, Robert C. Liddington, José G. Vilches-Moure, Constantine A. Stratakis, Ze’ev A. Ronai

JCI Insight. 2017 Dec 7; 2(23): e97128. Published online 2017 Dec 7. doi: 10.1172/jci.insight.97128

PMCID:: PMC5752272

Abstract Article PDF–9.0M

Select item 54587573.

The SIAH E3 ubiquitin ligases promote Wnt/β-catenin signaling through mediating Wnt-induced Axin degradation

Lei Ji, Bo Jiang, Xiaomo Jiang, Olga Charlat, Amy Chen, Craig Mickanin, Andreas Bauer, Wenqing Xu, Xiaoxue Yan, Feng Cong

Genes Dev. 2017 May 1; 31(9): 904–915. doi: 10.1101/gad.300053.117

PMCID:: PMC5458757

Abstract Article PDF–523K

Select item 43118014.

Central role of SIAH inhibition in DCC-dependent cardioprotection provoked by netrin-1/NO

Qiang Li, Ping Wang, Keqiang Ye, Hua Cai

Proc Natl Acad Sci U S A. 2015 Jan 20; 112(3): 899–904. Published online 2015 Jan 5. doi: 10.1073/pnas.1420695112

PMCID:: PMC4311801

Abstract Article PDF–1.5M

Select item 40144255.

Fine Tuning of the UPR by the Ubiquitin Ligases Siah1/2

Marzia Scortegagna, Hyungsoo Kim, Jian-Liang Li, Hang Yao, Laurence M. Brill, Jaeseok Han, Eric Lau, David Bowtell, Gabriel Haddad, Randal J. Kaufman, Ze'ev A. Ronai

PLoS Genet. 2014 May; 10(5): e1004348. Published online 2014 May 8. doi: 10.1371/journal.pgen.1004348

PMCID:: PMC4014425

Abstract Article PDF–8.6M

Select item 36959026.

MOR Is Not Enough: Identification of Novel mu-Opioid Receptor Interacting Proteins Using Traditional and Modified Membrane Yeast Two-Hybrid Screens

Jessica Petko, Stephanie Justice-Bitner, Jay Jin, Victoria Wong, Saranya Kittanakom, Thomas N. Ferraro, Igor Stagljar, Robert Levenson

PLoS One. 2013; 8(6): e67608. Published online 2013 Jun 28. doi: 10.1371/journal.pone.0067608

PMCID:: PMC3695902

Abstract Article PDF–3.7M

Select item 34615127.

S-nitrosylation of B23/nucleophosmin by GAPDH protects cells from the SIAH1–GAPDH death cascade

Sang Bae Lee, Chung Kwon Kim, Kyung-Hoon Lee, Jee-Yin Ahn

J Cell Biol. 2012 Oct 1; 199(1): 65–76. doi: 10.1083/jcb.201205015

PMCID:: PMC3461512

Abstract Article PDF–3.1M

Select item 33609558.

Fine-Tuning of Drp1/Fis1 Availability by AKAP121/Siah2 Regulates Mitochondrial Adaptation to Hypoxia

Hyungsoo Kim, Maria C. Scimia, Deepti Wilkinson, Ramon D. Trelles, Malcolm R. Wood, David Bowtell, Andrew Dillin, Mark Mercola, Ze’ev A. Ronai

Mol Cell. Author manuscript; available in PMC 2012 Nov 18.

Published in final edited form as: Mol Cell. 2011 Nov 18; 44(4): 532–544. doi: 10.1016/j.molcel.2011.08.045

PMCID:: PMC3360955

Abstract Article PDF–5.9M

Select item 32226619.

miR-135A Regulates Preimplantation Embryo Development through Down-Regulation of E3 Ubiquitin Ligase Seven in Absentia Homolog 1A (SIAH1A) Expression

Ronald T. K. Pang, Wei-Min Liu, Carmen O. N. Leung, Tian-Min Ye, Peter C. K. Kwan, Kai-Fai Lee, William S. B. Yeung

PLoS One. 2011; 6(11): e27878. Published online 2011 Nov 22. doi: 10.1371/journal.pone.0027878

PMCID:: PMC3222661

Abstract Article PDF–774K

Select item 318019810.

Siah1/SIP regulates p27^kip1 stability and cell migration under metabolic stress

Yoshito Nagano, Toru Fukushima, Kazuo Okemoto, Keiichiro Tanaka, David DL Bowtell, Ze'ev A Ronai, John C Reed, Shu-ichi Matsuzawa

Cell Cycle. 2011 Aug 1; 10(15): 2592–2602. Published online 2011 Aug 1. doi: 10.4161/cc.10.15.16912

PMCID:: PMC3180198

Abstract Article PDF–2.9M

Select item 317805911.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 305570912.

In silico QTL mapping of basal liver iron levels in inbred mouse strains

Stela McLachlan, Seung-Min Lee, Teresa M. Steele, Paula L. Hawthorne, Matthew A. Zapala, Eleazar Eskin, Nicholas J. Schork, Gregory J. Anderson, Chris D. Vulpe

Physiol Genomics. 2011 Feb; 43(3): 136–147. Published online 2010 Nov 9. doi: 10.1152/physiolgenomics.00025.2010

PMCID:: PMC3055709

Abstract Article

Select item 302253413.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 300090314.

Inhibition of Siah ubiquitin ligase function

Andreas Möller, Colin M. House, Christina S.F. Wong, Denis B. Scanlon, Mira C.P. Liu, Ze’ev Ronai, David D.L. Bowtell

Oncogene. Author manuscript; available in PMC 2010 Dec 11.

Published in final edited form as: Oncogene. 2009 Jan 15; 28(2): 289–296. Published online 2008 Oct 13. doi: 10.1038/onc.2008.382

PMCID:: PMC3000903

Abstract Article PDF–1.3M

Select item 293810015.

Interactome Mapping of the Phosphatidylinositol 3-Kinase-Mammalian Target of Rapamycin Pathway Identifies Deformed Epidermal Autoregulatory Factor-1 as a New Glycogen Synthase Kinase-3 Interactor

Fanny Pilot-Storck, Emilie Chopin, Jean-François Rual, Anais Baudot, Pavel Dobrokhotov, Marc Robinson-Rechavi, Christine Brun, Michael E. Cusick, David E. Hill, Laurent Schaeffer, Marc Vidal, Evelyne Goillot

Mol Cell Proteomics. 2010 Jul; 9(7): 1578–1593. Published online 2010 Apr 5. doi: 10.1074/mcp.M900568-MCP200

PMCID:: PMC2938100

Abstract Article PDF–1.1M

Select item 255627016.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108