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Select item 110041851.

DHX9 maintains epithelial homeostasis by restraining R-loop-mediated genomic instability in intestinal stem cells

Xingxing Ren, Qiuyuan Liu, Peirong Zhou, Tingyue Zhou, Decai Wang, Qiao Mei, Richard A. Flavell, Zhanju Liu, Mingsong Li, Wen Pan, Shu Zhu

Nat Commun. 2024; 15: 3080. Published online 2024 Apr 9. doi: 10.1038/s41467-024-47235-2

PMCID:: PMC11004185

Abstract Article PDF–11M

Select item 108145792.

PARP1, DIDO3, and DHX9 Proteins Mutually Interact in Mouse Fibroblasts, with Effects on DNA Replication Dynamics, Senescence, and Oncogenic Transformation

Agnes Fütterer, Sara Rodriguez-Acebes, Juan Méndez, Julio Gutiérrez, Carlos Martínez-A

Cells. 2024 Jan; 13(2): 159. Published online 2024 Jan 15. doi: 10.3390/cells13020159

PMCID:: PMC10814579

Abstract Article PDF–10M

Select item 106721663.

Mature mRNA processing that deletes 3′ end sequences directs translational activation and embryonic development

Yuki Takada, Ludivine Fierro, Keisuke Sato, Takahiro Sanada, Anna Ishii, Takehiro Yamamoto, Tomoya Kotani

Sci Adv. 2023 Nov 24; 9(47): eadg6532. Published online 2023 Nov 24. doi: 10.1126/sciadv.adg6532

PMCID:: PMC10672166

Abstract Article PDF–2.2M

Select item 105678264.

DHX9 Strengthens Atherosclerosis Progression By Promoting Inflammation in Macrophages

Ning Huangfu, Hongchuang Ma, Mengyun Tian, Jie Zhang, Yong Wang, Zhenwei Li, Xiaomin Chen, Hanbin Cui

Inflammation. 2023; 46(5): 1725–1738. Published online 2023 Jun 16. doi: 10.1007/s10753-023-01836-z

PMCID:: PMC10567826

Abstract Article PDF–3.5M

Select item 104321485.

Monoallelic variation in DHX9, the gene encoding the DExH-box helicase DHX9, underlies neurodevelopment disorders and Charcot-Marie-Tooth disease

Daniel G. Calame, Tianyu Guo, Chen Wang, Lillian Garrett, Angad Jolly, Moez Dawood, Alina Kurolap, Noa Zunz Henig, Jawid M. Fatih, Isabella Herman, Haowei Du, Tadahiro Mitani, Lore Becker, Birgit Rathkolb, Raffaele Gerlini, Claudia Seisenberger, Susan Marschall, Jill V. Hunter, Amanda Gerard, Alexis Heidlebaugh, Thomas Challman, Rebecca C. Spillmann, Shalini N. Jhangiani, Zeynep Coban-Akdemir, Seema Lalani, Lingxiao Liu, Anya Revah-Politi, Alejandro Iglesias, Edwin Guzman, Evan Baugh, Nathalie Boddaert, Sophie Rondeau, Clothide Ormieres, Giulia Barcia, Queenie K.G. Tan, Isabelle Thiffault, Tomi Pastinen, Kazim Sheikh, Suur Biliciler, Davide Mei, Federico Melani, Vandana Shashi, Yuval Yaron, Mary Steele, Emma Wakeling, Elsebet Østergaard, Lusine Nazaryan-Petersen, Undiagnosed Diseases Network, Francisca Millan, Teresa Santiago-Sim, Julien Thevenon, Ange-Line Bruel, Christel Thauvin-Robinet, Denny Popp, Konrad Platzer, Pawel Gawlinski, Wojciech Wiszniewski, Dana Marafi, Davut Pehlivan, Jennifer E. Posey, Richard A. Gibbs, Valerie Gailus-Durner, Renzo Guerrini, Helmut Fuchs, Martin Hrabě de Angelis, Sabine M. Hölter, Hoi-Hung Cheung, Shen Gu, James R. Lupski

Am J Hum Genet. 2023 Aug 3; 110(8): 1394–1413. Published online 2023 Jul 18. doi: 10.1016/j.ajhg.2023.06.013

PMCID:: PMC10432148

Abstract Article PDF–4.2M

Select item 98976716.

Nucleic DHX9 cooperates with STAT1 to transcribe interferon-stimulated genes

Xingxing Ren, Decai Wang, Guorong Zhang, Tingyue Zhou, Zheng Wei, Yi Yang, Yunjiang Zheng, Xuqiu Lei, Wanyin Tao, Anmin Wang, Mingsong Li, Richard A. Flavell, Shu Zhu

Sci Adv. 2023 Feb; 9(5): eadd5005. Published online 2023 Feb 3. doi: 10.1126/sciadv.add5005

PMCID:: PMC9897671

Abstract Article PDF–1.8M

Select item 96038607.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 92038518.

Cytosolic Nuclear Sensor Dhx9 Controls Medullary Thymic Epithelial Cell Differentiation by p53-Mediated Pathways

Xue Dong, Jiayu Zhang, Qian Zhang, Zhanfeng Liang, Yanan Xu, Yong Zhao, Baojun Zhang

Front Immunol. 2022; 13: 896472. Published online 2022 Jun 3. doi: 10.3389/fimmu.2022.896472

PMCID:: PMC9203851

Abstract Article PDF–7.2M

Select item 88276549.

DExD/H-box helicase 9 intrinsically controls CD8⁺ T cell–mediated antiviral response through noncanonical mechanisms

Anjun Jiao, Chenming Sun, Xin Wang, Lei Lei, Haiyan Liu, Wenhui Li, Xiaofeng Yang, Huiqiang Zheng, Renyi Ding, Kun Zhu, Yanhong Su, Cangang Zhang, Lianjun Zhang, Baojun Zhang

Sci Adv. 2022 Feb; 8(6): eabk2691. Published online 2022 Feb 9. doi: 10.1126/sciadv.abk2691

PMCID:: PMC8827654

Abstract Article PDF–6.1M

Select item 793877010.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 669277011.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 633346012.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 624418313.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 615862214.

A DNA-sensing–independent role of a nuclear RNA helicase, DHX9, in stimulation of NF-κB–mediated innate immunity against DNA virus infection

Yee Ching Ng, Woo-Chang Chung, Hye-Ri Kang, Hye-Jeong Cho, Eun-Byeol Park, Suk-Jo Kang, Moon Jung Song

Nucleic Acids Res. 2018 Sep 28; 46(17): 9011–9026. Published online 2018 Aug 20. doi: 10.1093/nar/gky742

PMCID:: PMC6158622

Abstract Article PDF–5.7M

Select item 578737515.

Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells

Shu Zhu, Siyuan Ding, Penghua Wang, Zheng Wei, Wen Pan, Noah W Palm, Yi Yang, Hua Yu, Hua-Bing Li, Geng Wang, Xuqiu Lei, Marcel R. de Zoete, Jun Zhao, Yunjiang Zheng, Haiwei Chen, Yujiao Zhao, Kellie A. Jurado, Ningguo Feng, Liang Shan, Yuval Kluger, Jun Lu, Clara Abraham, Erol Fikrig, Harry B. Greenberg, Richard A. Flavell

Nature. Author manuscript; available in PMC 2018 Jan 28.

Published in final edited form as: Nature. 2017 Jun 29; 546(7660): 667–670. Published online 2017 Jun 21. doi: 10.1038/nature22967

PMCID:: PMC5787375

Abstract Article PDF–1.5M

Select item 546738916.

Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction

Andrew C. Hiday, Michael C. Edler, Asma B. Salek, Cameron W. Morris, Morrent Thang, Tyler J. Rentz, Kristie L. Rose, Lisa M. Jones, Anthony J. Baucum, II

Neural Plast. 2017; 2017: 4153076. Published online 2017 May 28. doi: 10.1155/2017/4153076