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Items: 1 to 20 of 28

1.
BRSK2 in pancreatic β cells promotes hyperinsulinemia-coupled insulin resistance and its genetic variants are associated with human type 2 diabetes
Rufeng Xu, Kaiyuan Wang, Zhengjian Yao, Yan Zhang, Li Jin, Jing Pang, Yuncai Zhou, Kai Wang, Dechen Liu, Yaqin Zhang, Peng Sun, Fuqiang Wang, Xiaoai Chang, Tengli Liu, Shusen Wang, Yalin Zhang, Shuyong Lin, Cheng Hu, Yunxia Zhu, Xiao Han
J Mol Cell Biol. 2023 May; 15(5): mjad033. Published online 2023 May 15. doi: 10.1093/jmcb/mjad033
PMCID:
PMC10782904
AbstractArticlePDF–2.6M
2.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
3.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
4.
Isozyme-Specific Role of SAD-A in Neuronal Migration During Development of Cerebral Cortex
Keiko Nakanishi, Hiroyuki Niida, Hidenori Tabata, Tsuyoshi Ito, Yuki Hori, Madoka Hattori, Yoshikazu Johmura, Chisato Yamada, Takashi Ueda, Kosei Takeuchi, Kenichiro Yamada, Koh-ichi Nagata, Nobuaki Wakamatsu, Masashi Kishi, Y Albert Pan, Shinya Ugawa, Shoichi Shimada, Joshua R Sanes, Yujiro Higashi, Makoto Nakanishi
Cereb Cortex. 2019 Aug; 29(9): 3738–3751. Published online 2018 Oct 11. doi: 10.1093/cercor/bhy253
PMCID:
PMC7335017
AbstractArticlePDF–1.9M
5.
STK11 is required for the normal program of ciliated cell differentiation in airways
Qiqi Chu, Changfu Yao, Xiangbing Qi, Barry Raymond Stripp, Nan Tang
Cell Discov. 2019; 5: 36. Published online 2019 Jul 16. doi: 10.1038/s41421-019-0104-z
PMCID:
PMC6796922
AbstractArticlePDF–4.6M
6.
SAD-A Promotes Glucose-Stimulated Insulin Secretion Through Phosphorylation and Inhibition of GDIα in Male Islet β Cells
Jia Nie, Chao Sun, Zhijie Chang, Nicolas Musi, Yuguang Shi
Endocrinology. 2018 Aug; 159(8): 3036–3047. Published online 2018 Jun 4. doi: 10.1210/en.2017-03243
PMCID:
PMC6693047
AbstractArticle
7.
The loss of the kinases SadA and SadB results in early neuronal apoptosis and a reduced number of progenitors
Pratibha Dhumale, Sindhu Menon, Joanna Chiang, Andreas W. Püschel
PLoS One. 2018; 13(4): e0196698. Published online 2018 Apr 26. doi: 10.1371/journal.pone.0196698
PMCID:
PMC5919486
AbstractArticlePDF–2.6M
8.
LKB1 and AMPK regulate synaptic remodeling in old age
Melanie A Samuel, P Emanuela Voinescu, Brendan N Lilley, Rafa de Cabo, Marc Foretz, Benoit Viollet, Basil Pawlyk, Michael A Sandberg, Demetrios G Vavvas, Joshua R Sanes
Nat Neurosci. Author manuscript; available in PMC 2017 Mar 28.
Published in final edited form as: Nat Neurosci. 2014 Sep; 17(9): 1190–1197. Published online 2014 Aug 3. doi: 10.1038/nn.3772
PMCID:
PMC5369022
AbstractArticlePDF–2.0M
9.
Structural insight into the mechanism of synergistic autoinhibition of SAD kinases
Jing-Xiang Wu, Yun-Sheng Cheng, Jue Wang, Lei Chen, Mei Ding, Jia-Wei Wu
Nat Commun. 2015; 6: 8953. Published online 2015 Dec 2. doi: 10.1038/ncomms9953
PMCID:
PMC4686854
AbstractArticlePDF–2.3M
10.
SAD kinases control the maturation of nerve terminals in the mammalian peripheral and central nervous systems
Brendan N. Lilley, Arjun Krishnaswamy, Zhi Wang, Masashi Kishi, Eric Frank, Joshua R. Sanes
Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3): 1138–1143. Published online 2014 Jan 6. doi: 10.1073/pnas.1321990111
PMCID:
PMC3903204
AbstractArticlePDF–1.6M
11.
SAD-A and AMPK kinases: The “yin and yang” regulators of mTORC1 signaling in pancreatic β cells
Jia Nie, Xiao Han, Yuguang Shi
Cell Cycle. 2013 Nov 1; 12(21): 3366–3369. Published online 2013 Sep 18. doi: 10.4161/cc.26496
PMCID:
PMC3895425
AbstractArticlePDF–253K
12.
SAD-A kinase controls islet β-cell size and function as a mediator of mTORC1 signaling
Jia Nie, Xiaolei Liu, Brendan N. Lilley, Hai Zhang, Y. Albert Pan, Scot R. Kimball, Jun Zhang, Weiping Zhang, Li Wang, Leonard S. Jefferson, Joshua R. Sanes, Xiao Han, Yuguang Shi
Proc Natl Acad Sci U S A. 2013 Aug 20; 110(34): 13857–13862. Published online 2013 Aug 6. doi: 10.1073/pnas.1307698110
PMCID:
PMC3752253
AbstractArticlePDF–1.3M
13.
SAD kinases sculpt axonal arbors of sensory neurons through long and short-term responses to neurotrophin signals
Brendan N. Lilley, Y. Albert Pan, Joshua R. Sanes
Neuron. Author manuscript; available in PMC 2014 Jul 10.
Published in final edited form as: Neuron. 2013 Jul 10; 79(1): 39–53. Published online 2013 Jun 20. doi: 10.1016/j.neuron.2013.05.017
PMCID:
PMC3725037
AbstractArticlePDF–7.2M
14.
SAD-A Potentiates Glucose-Stimulated Insulin Secretion as a Mediator of Glucagon-Like Peptide 1 Response in Pancreatic β Cells
Jia Nie, Brendan N. Lilley, Y. Albert Pan, Omar Faruque, Xiaolei Liu, Weiping Zhang, Joshua R. Sanes, Xiao Han, Yuguang Shi
Mol Cell Biol. 2013 Jul; 33(13): 2527–2534. doi: 10.1128/MCB.00285-13
PMCID:
PMC3700116
AbstractArticlePDF–1.1M
15.
Interaction of PDK1 with Phosphoinositides Is Essential for Neuronal Differentiation but Dispensable for Neuronal Survival
Tinatin Zurashvili, Lluís Cordón-Barris, Gerard Ruiz-Babot, Xiangyu Zhou, Jose M. Lizcano, Nestor Gómez, Lydia Giménez-Llort, Jose R. Bayascas
Mol Cell Biol. 2013 Mar; 33(5): 1027–1040. doi: 10.1128/MCB.01052-12
Correction in:
Mol Cell Biol. 2016 Jun 15; 36(12): 1818.
PMCID:
PMC3623085
AbstractArticlePDF–3.4M
16.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
17.
Brain-selective Kinase 2 (BRSK2) Phosphorylation on PCTAIRE1 Negatively Regulates Glucose-stimulated Insulin Secretion in Pancreatic β-Cells
Xin-Ya Chen, Xiu-Ting Gu, Hexige Saiyin, Bo Wan, Yu-Jing Zhang, Jing Li, Ying-Li Wang, Rui Gao, Yu-Fan Wang, Wei-Ping Dong, Sonia M. Najjar, Chen-Yu Zhang, Han-Fei Ding, Jun O. Liu, Long Yu
J Biol Chem. 2012 Aug 31; 287(36): 30368–30375. Published online 2012 Jul 13. doi: 10.1074/jbc.M112.375618
PMCID:
PMC3436288
AbstractArticlePDF–1.3M
18.
Synapses of Amphids Defective (SAD-A) Kinase Promotes Glucose-stimulated Insulin Secretion through Activation of p21-activated Kinase (PAK1) in Pancreatic β-Cells
Jia Nie, Chao Sun, Omar Faruque, Guangming Ye, Jia Li, Qiangrong Liang, Zhijie Chang, Wannian Yang, Xiao Han, Yuguang Shi
J Biol Chem. 2012 Jul 27; 287(31): 26435–26444. Published online 2012 Jun 5. doi: 10.1074/jbc.M112.378372
PMCID:
PMC3406726
AbstractArticlePDF–3.2M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M

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