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Items: 1 to 20 of 38

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes
Pablo Montañés-Agudo, Simona Aufiero, Eva N Schepers, Ingeborg van der Made, Lucia Cócera-Ortega, Auriane C Ernault, Stéphane Richard, Diederik W D Kuster, Vincent M Christoffels, Yigal M Pinto, Esther E Creemers
Cardiovasc Res. 2023 May; 119(5): 1161–1174. Published online 2023 Jan 11. doi: 10.1093/cvr/cvad007
PMCID:
PMC10202634
AbstractArticlePDF–2.0M
3.
Deciphering postnatal limb development at single-cell resolution
Manman Gao, Xizhe Liu, Peng Guo, Jianmin Wang, Junhong Li, Wentao Wang, Martin J. Stoddart, Sibylle Grad, Zhen Li, Huachuan Wu, Baoliang Li, Zhongyuan He, Guangqian Zhou, Shaoyu Liu, Weimin Zhu, Dafu Chen, Xuenong Zou, Zhiyu Zhou
iScience. 2023 Jan 20; 26(1): 105808. Published online 2022 Dec 13. doi: 10.1016/j.isci.2022.105808
PMCID:
PMC9813795
AbstractArticlePDF–13M
4.
PRDM16 Is a Compact Myocardium-Enriched Transcription Factor Required to Maintain Compact Myocardial Cardiomyocyte Identity in Left Ventricle
Tongbin Wu, Zhengyu Liang, Zengming Zhang, Canzhao Liu, Lunfeng Zhang, Yusu Gu, Kirk L. Peterson, Sylvia M. Evans, Xiang-Dong Fu, Ju Chen
Circulation. Author manuscript; available in PMC 2023 Feb 22.
Published in final edited form as: Circulation. 2022 Feb 22; 145(8): 586–602. Published online 2021 Dec 17. doi: 10.1161/CIRCULATIONAHA.121.056666
PMCID:
PMC8860879
AbstractArticlePDF–2.5M
5.
Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network
Changming Tan, Siting Zhu, Zee Chen, Canzhao Liu, Yang E. Li, Mason Zhu, Zhiyuan Zhang, Zhiwei Zhang, Lunfeng Zhang, Yusu Gu, Zhengyu Liang, Thomas G. Boyer, Kunfu Ouyang, Sylvia M. Evans, Xi Fang
PLoS Genet. 2021 Sep; 17(9): e1009785. Published online 2021 Sep 10. doi: 10.1371/journal.pgen.1009785
PMCID:
PMC8432849
AbstractArticlePDF–3.4M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure
Beth A Firulli, Rajani M George, Jade Harkin, Kevin P Toolan, Hongyu Gao, Yunlong Liu, Wenjun Zhang, Loren J Field, Ying Liu, Weinian Shou, Ronald Mark Payne, Michael Rubart-von der Lohe, Anthony B Firulli
Cardiovasc Res. 2020 Mar 1; 116(3): 605–618. Published online 2019 Jul 9. doi: 10.1093/cvr/cvz182
PMCID:
PMC7252443
AbstractArticlePDF–1.8M
8.
O-linked β-N-acetylglucosamine transferase plays an essential role in heart development through regulating angiopoietin-1
Yongxin Mu, Houzhi Yu, Tongbin Wu, Jianlin Zhang, Sylvia M. Evans, Ju Chen
PLoS Genet. 2020 Apr; 16(4): e1008730. Published online 2020 Apr 6. doi: 10.1371/journal.pgen.1008730
PMCID:
PMC7182263
AbstractArticlePDF–4.0M
9.
CHD4 and the NuRD complex directly control cardiac sarcomere formation
Caralynn M. Wilczewski, Austin J. Hepperla, Takashi Shimbo, Lauren Wasson, Zachary L. Robbe, Ian J. Davis, Paul A. Wade, Frank L. Conlon
Proc Natl Acad Sci U S A. 2018 Jun 26; 115(26): 6727–6732. Published online 2018 Jun 11. doi: 10.1073/pnas.1722219115
PMCID:
PMC6042121
AbstractArticlePDF–2.0M
10.
Gene expression profiling in the developing secondary palate in the absence of Tbx1 function
Maria Zoupa, Guilherme Machado Xavier, Stephanie Bryan, Ioannis Theologidis, Matthew Arno, Martyn T. Cobourne
BMC Genomics. 2018; 19: 429. Published online 2018 Jun 4. doi: 10.1186/s12864-018-4782-y
PMCID:
PMC5987606
AbstractArticlePDF–2.6M
11.
HIC2 regulates isoform switching during maturation of the cardiovascular system
Iain M. Dykes, Kelly Lammerts van Bueren, Peter J. Scambler
J Mol Cell Cardiol. 2018 Jan; 114: 29–37. doi: 10.1016/j.yjmcc.2017.10.007
Correction in:
J Mol Cell Cardiol. 2023 Oct; 183: 102.
PMCID:
PMC5807030
AbstractArticlePDF–800K
12.
CTCF counter-regulates cardiomyocyte development and maturation programs in the embryonic heart
Melisa Gomez-Velazquez, Claudio Badia-Careaga, Ana Victoria Lechuga-Vieco, Rocio Nieto-Arellano, Juan J. Tena, Isabel Rollan, Alba Alvarez, Carlos Torroja, Eva F. Caceres, Anna R. Roy, Niels Galjart, Paul Delgado-Olguin, Fatima Sanchez-Cabo, Jose Antonio Enriquez, Jose Luis Gomez-Skarmeta, Miguel Manzanares
PLoS Genet. 2017 Aug; 13(8): e1006985. Published online 2017 Aug 28. doi: 10.1371/journal.pgen.1006985
PMCID:
PMC5591014
AbstractArticlePDF–20M
13.
Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle
Iori Sakakibara, Maud Wurmser, Matthieu Dos Santos, Marc Santolini, Serge Ducommun, Romain Davaze, Anthony Guernec, Kei Sakamoto, Pascal Maire
Skelet Muscle. 2016; 6(1): 30. Published online 2016 Sep 5. doi: 10.1186/s13395-016-0102-x
PMCID:
PMC5011358
AbstractArticlePDF–3.5M
14.
HIRA Is Required for Heart Development and Directly Regulates Tnni2 and Tnnt3
Daniel Dilg, Rasha Noureldin M. Saleh, Sarah Elizabeth Lee Phelps, Yoann Rose, Laurent Dupays, Cian Murphy, Timothy Mohun, Robert H. Anderson, Peter J. Scambler, Ariane L. A. Chapgier
PLoS One. 2016; 11(8): e0161096. Published online 2016 Aug 12. doi: 10.1371/journal.pone.0161096
PMCID:
PMC4982693
AbstractArticlePDF–18M
15.
IGF2BP2/IMP2 Deficient Mice Resist Obesity through enhanced translation of Ucp1 mRNA and other mRNAs encoding Mitochondrial Proteins
Ning Dai, Liping Zhao, Diedra Wrighting, Dana Krämer, Amit Majithia, Yanqun Wang, Valentin Cracan, Diego Borges-Rivera, Vamsi K. Mootha, Matthias Nahrendorf, David R. Thorburn, Liliana Minichiello, David Altshuler, Joseph Avruch
Cell Metab. Author manuscript; available in PMC 2016 Apr 7.
Published in final edited form as: Cell Metab. 2015 Apr 7; 21(4): 609–621. doi: 10.1016/j.cmet.2015.03.006
PMCID:
PMC4663978
AbstractArticlePDF–2.9M
16.
Sequential Binding of MEIS1 and NKX2-5 on the Popdc2 Gene: A Mechanism for Spatiotemporal Regulation of Enhancers during Cardiogenesis
Laurent Dupays, Catherine Shang, Robert Wilson, Surendra Kotecha, Sophie Wood, Norma Towers, Timothy Mohun
Cell Rep. 2015 Oct 6; 13(1): 183–195. Published online 2015 Sep 24. doi: 10.1016/j.celrep.2015.08.065
PMCID:
PMC4597108
AbstractArticle
17.
Abnormal Mammary Development in 129:STAT1-Null Mice is Stroma-Dependent
Jane Q. Chen, Hidetoshi Mori, Robert D. Cardiff, Josephine F. Trott, Russell C. Hovey, Neil E. Hubbard, Jesse A. Engelberg, Clifford G. Tepper, Brandon J. Willis, Imran H. Khan, Resmi K. Ravindran, Szeman R. Chan, Robert D. Schreiber, Alexander D. Borowsky
PLoS One. 2015; 10(6): e0129895. Published online 2015 Jun 15. doi: 10.1371/journal.pone.0129895
PMCID:
PMC4468083
AbstractArticlePDF–12M
18.
Essential Role of the Zinc Finger Transcription Factor Casz1 for Mammalian Cardiac Morphogenesis and Development
Zhihui Liu, Wenling Li, Xuefei Ma, Nancy Ding, Francesco Spallotta, Eileen Southon, Lino Tessarollo, Carlo Gaetano, Yoh-suke Mukouyama, Carol J. Thiele
J Biol Chem. 2014 Oct 24; 289(43): 29801–29816. Published online 2014 Sep 4. doi: 10.1074/jbc.M114.570416
PMCID:
PMC4207993
AbstractArticlePDF–7.5M
19.
A Gain-of-Function Mutation in Tnni2 Impeded Bone Development through Increasing Hif3a Expression in DA2B Mice
Xiaoquan Zhu, Fengchao Wang, Yanyang Zhao, Peng Yang, Jun Chen, Hanzi Sun, Lei Liu, Wenjun Li, Lin Pan, Yanru Guo, Zhaohui Kou, Yu Zhang, Cheng Zhou, Jiang He, Xue Zhang, Jianxin Li, Weitian Han, Jian Li, Guanghui Liu, Shaorong Gao, Ze Yang
PLoS Genet. 2014 Oct; 10(10): e1004589. Published online 2014 Oct 23. doi: 10.1371/journal.pgen.1004589
PMCID:
PMC4207604
AbstractArticlePDF–3.6M
20.
The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse
Phillip Grote, Lars Wittler, Sandra Währisch, David Hendrix, Arica Beisaw, Karol Macura, Gaby Bläss, Manolis Kellis, Martin Werber, Bernhard G. Herrmann
Dev Cell. Author manuscript; available in PMC 2014 Aug 29.
Published in final edited form as: Dev Cell. 2013 Jan 28; 24(2): 206–214. doi: 10.1016/j.devcel.2012.12.012
PMCID:
PMC4149175
AbstractArticlePDF–820K

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