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Items: 1 to 20 of 89

1.
Cartilage tissues regulate systemic aging via ectonucleotide pyrophosphatase/phosphodiesterase 1 in mice
Takahiro Arima, Kazuki Sugimoto, Takuya Taniwaki, Kazuya Maeda, Yuto Shibata, Makoto Tateyama, Tatsuki Karasugi, Takuya Tokunaga, Takanao Sueyoshi, Satoshi Hisanaga, Tetsuro Masuda, Yusuke Uehara, Masaki Yugami, Kozo Matsushita, Ryuji Yonemitsu, Junki Kawakami, Naoto Yoshimura, Shuntaro Tanimura, Hajime Kato, Nobuaki Ito, Kenichi Inoue, Kana Bando, Takayuki Nakamura, Takeshi Miyamoto
J Biol Chem. 2024 Jan; 300(1): 105512. Published online 2023 Nov 30. doi: 10.1016/j.jbc.2023.105512
PMCID:
PMC10777000
AbstractArticlePDF–2.1M
2.
Enpp1 deficiency caused chondrocyte apoptosis by inhibiting AMPK signaling pathway
Zhiqiang Gao, Qiang Wang, Kai Guo, Xinhua Li, Yufeng Huang
J Orthop Surg Res. 2023; 18: 462. Published online 2023 Jun 27. doi: 10.1186/s13018-023-03923-1
PMCID:
PMC10294376
AbstractArticlePDF–5.6M
3.
Npp1 prevents external tooth root resorption by regulation of cervical cementum integrity
Hwajung Choi, Liu Yang, Yudong Liu, Ju-Kyung Jeong, Eui-Sic Cho
Sci Rep. 2022; 12: 21158. Published online 2022 Dec 7. doi: 10.1038/s41598-022-25846-3
PMCID:
PMC9729310
AbstractArticlePDF–6.2M
4.
Catalysis-independent ENPP1 protein signaling regulates mammalian bone mass
Kristin Zimmerman, Xiaochen Li, Simon von Kroge, Paul Stabach, Ethan R. Lester, Emily Y. Chu, Shivani Srivastava, Martha J. Somerman, Steven M. Tommasini, Björn Busse, Thorsten Schinke, Thomas O. Carpenter, Ralf Oheim, Demetrios T. Braddock
J Bone Miner Res. Author manuscript; available in PMC 2023 Sep 1.
Published in final edited form as: J Bone Miner Res. 2022 Sep; 37(9): 1733–1749. Published online 2022 Jul 29. doi: 10.1002/jbmr.4640
PMCID:
PMC9709593
AbstractArticlePDF–3.1M
5.
Osteoblast-specific deficiency of ectonucleotide pyrophosphatase or phosphodiesterase-1 engenders insulin resistance in high-fat diet fed mice
Fiona L. Roberts, Nabil A. Rashdan, Kanchan Phadwal, Greg R. Markby, Scott Dillon, Janna Zoll, Julian Berger, Elspeth Milne, Isabel R. Orriss, Gerard Karsenty, Olivier Le Saux, Nicholas M. Morton, Colin Farquharson, Vicky E. MacRae
J Cell Physiol. Author manuscript; available in PMC 2022 Nov 15.
Published in final edited form as: J Cell Physiol. 2021 Jun; 236(6): 4614–4624. Published online 2020 Dec 10. doi: 10.1002/jcp.30194
PMCID:
PMC9665351
AbstractArticlePDF–1.6M
6.
ENPP1 deletion causes mouse osteoporosis via the MKK3/p38 MAPK/PCNA signaling pathway
Qiang Wang, Zhiqiang Gao, Kai Guo, Jiawei Lu, Feng Wang, Yufeng Huang, Desheng Wu
J Orthop Surg Res. 2022; 17: 455. Published online 2022 Oct 15. doi: 10.1186/s13018-022-03349-1
PMCID:
PMC9571425
AbstractArticlePDF–2.2M
7.
ENPP1’s regulation of extracellular cGAMP is a ubiquitous mechanism of attenuating STING signaling
Jacqueline A. Carozza, Anthony F. Cordova, Jenifer A. Brown, Yasmeen AlSaif, Volker Böhnert, Xujun Cao, Rachel E. Mardjuki, Gemini Skariah, Daniel Fernandez, Lingyin Li
Proc Natl Acad Sci U S A. 2022 May 24; 119(21): e2119189119. Published online 2022 May 19. doi: 10.1073/pnas.2119189119
PMCID:
PMC9173814
AbstractArticlePDF–1.8M
8.
Response of the ENPP1-Deficient Skeletal Phenotype to Oral Phosphate Supplementation and/or Enzyme Replacement Therapy: Comparative Studies in Humans and Mice
Carlos R Ferreira, Dillon Kavanagh, Ralf Oheim, Kristin Zimmerman, Julian Stürznickel, Xiaofeng Li, Paul Stabach, R Luke Rettig, Logan Calderone, Colin MacKichan, Aaron Wang, Hunter A Hutchinson, Tracy Nelson, Steven M Tommasini, Simon von Kroge, Imke AK Fiedler, Ethan R Lester, Gilbert W Moeckel, Björn Busse, Thorsten Schinke, Thomas O Carpenter, Michael A Levine, Mark C Horowitz, Demetrios T Braddock
J Bone Miner Res. Author manuscript; available in PMC 2022 May 1.
Published in final edited form as: J Bone Miner Res. 2021 May; 36(5): 942–955. Published online 2021 Feb 18. doi: 10.1002/jbmr.4254
PMCID:
PMC8739051
AbstractArticlePDF–1.8M
9.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
10.
Ablation of Pyrophosphate Regulators Promotes Periodontal Regeneration
A. Nagasaki, K. Nagasaki, E.Y. Chu, B.D. Kear, W.D. Tadesse, S.E. Ferebee, L. Li, B.L. Foster, M.J. Somerman
J Dent Res. 2021 Jun; 100(6): 639–647. Published online 2020 Dec 24. doi: 10.1177/0022034520981854
PMCID:
PMC8142086
AbstractArticlePDF–1.6M
11.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
12.
Genetic pathways disrupted by ENPP1 deficiency provide insight into mechanisms of osteoporosis, osteomalacia, and paradoxical mineralization
Nathan D. Maulding, Dillon Kavanagh, Kristin Zimmerman, Gianfilippo Coppola, Thomas O. Carpenter, Nathaniel K. Jue, Demetrios T. Braddock
Bone. Author manuscript; available in PMC 2022 Jan 1.
Published in final edited form as: Bone. 2021 Jan; 142: 115656. Published online 2020 Sep 24. doi: 10.1016/j.bone.2020.115656
PMCID:
PMC7744330
AbstractArticlePDF–1.1M
13.
Genetic and pharmacologic modulation of cementogenesis via pyrophosphate regulators
E.Y. Chu, T.D. Vo, M.B. Chavez, A. Nagasaki, E. L. Mertz, F.H. Nociti, S.F. Aitken, D. Kavanagh, K. Zimmerman, X. Li, P.R. Stabach, D.T. Braddock, J.L. Millán, B.L. Foster, M.J. Somerman
Bone. Author manuscript; available in PMC 2021 Jul 1.
Published in final edited form as: Bone. 2020 Jul; 136: 115329. Published online 2020 Mar 26. doi: 10.1016/j.bone.2020.115329
PMCID:
PMC7482720
AbstractArticlePDF–3.2M
14.
Regulation of coenzyme A levels by degradation: the ‘Ins and Outs’
Philippe Naquet, Evan W. Kerr, Schuyler D. Vickers, Roberta Leonardi
Prog Lipid Res. Author manuscript; available in PMC 2021 Apr 1.
Published in final edited form as: Prog Lipid Res. 2020 Apr; 78: 101028. Published online 2020 Mar 29. doi: 10.1016/j.plipres.2020.101028
PMCID:
PMC7234920
AbstractArticlePDF–792K
15.
Human Heterozygous ENPP1 Deficiency Is Associated With Early Onset Osteoporosis, a Phenotype Recapitulated in a Mouse Model of Enpp1 Deficiency
Ralf Oheim, Kristin Zimmerman, Nathan D Maulding, Julian Stürznickel, Simon von Kroge, Dillon Kavanagh, Paul R Stabach, Uwe Kornak, Steven M Tommasini, Mark C Horowitz, Michael Amling, David Thompson, Thorsten Schinke, Björn Busse, Thomas O. Carpenter, Demetrios T Braddock
J Bone Miner Res. 2020 Mar; 35(3): 528–539. Published online 2019 Dec 5. doi: 10.1002/jbmr.3911
PMCID:
PMC7184798
AbstractArticlePDF–2.4M
16.
Plasma PPi Deficiency is the Major, But Not the Exclusive, Cause of Ectopic Mineralization in an Abcc6−/− Mouse Model of PXE
Jingyi Zhao, Joshua Kingman, John P. Sundberg, Jouni Uitto, Qiaoli Li
J Invest Dermatol. Author manuscript; available in PMC 2020 Mar 13.
Published in final edited form as: J Invest Dermatol. 2017 Nov; 137(11): 2336–2343. Published online 2017 Jun 23. doi: 10.1016/j.jid.2017.06.006
PMCID:
PMC7069658
AbstractArticlePDF–1.1M
17.
Role of macrophages and activated microglia in neuropathic pain associated with chronic progressive spinal cord compression
Naoto Takeura, Hideaki Nakajima, Shuji Watanabe, Kazuya Honjoh, Ai Takahashi, Akihiko Matsumine
Sci Rep. 2019; 9: 15656. Published online 2019 Oct 30. doi: 10.1038/s41598-019-52234-1
PMCID:
PMC6821913
AbstractArticlePDF–5.4M
18.
Reduced Orthodontic Tooth Movement in Enpp1 Mutant Mice with Hypercementosis
M. Wolf, M. Ao, M.B. Chavez, T.N. Kolli, V. Thumbigere-Math, K. Becker, E.Y. Chu, A. Jäger, M.J. Somerman, B.L. Foster
J Dent Res. 2018 Jul; 97(8): 937–945. Published online 2018 Mar 13. doi: 10.1177/0022034518759295
PMCID:
PMC6728553
AbstractArticlePDF–1.3M
19.
Mandibular dysmorphology due to abnormal embryonic osteogenesis in FGFR2-related craniosynostosis mice
Susan M. Motch Perrine, Meng Wu, Nicholas B. Stephens, Divya Kriti, Harm van Bakel, Ethylin Wang Jabs, Joan T. Richtsmeier
Dis Model Mech. 2019 May 1; 12(5): dmm038513. Published online 2019 May 30. doi: 10.1242/dmm.038513
PMCID:
PMC6550049
AbstractArticle
20.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M

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