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Items: 1 to 20 of 29

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Dual oxidase 1 is dispensable during Mycobacterium tuberculosis infection in mice
Tuhina Gupta, Demba Sarr, Kayla Fantone, Nuha Milad Ashtiwi, Kaori Sakamoto, Frederick D. Quinn, Balázs Rada
Front Immunol. 2023; 14: 1044703. Published online 2023 Mar 3. doi: 10.3389/fimmu.2023.1044703
PMCID:
PMC10020924
AbstractArticlePDF–5.4M
3.
Diet-induced obesity worsens allergen-induced type 2/type 17 inflammation in airways by enhancing DUOX1 activation
Aida Habibovic, Milena Hristova, Carolyn R. Morris, Miao-Chong Joy Lin, Litiele C. Cruz, Jennifer L. Ather, Miklós Geiszt, Vikas Anathy, Yvonne M. W. Janssen-Heininger, Matthew E. Poynter, Anne E. Dixon, Albert van der Vliet
Am J Physiol Lung Cell Mol Physiol. 2023 Feb 1; 324(2): L228–L242. Published online 2023 Jan 10. doi: 10.1152/ajplung.00331.2022
PMCID:
PMC9942905
AbstractArticle
4.
Macrophage-intrinsic DUOX1 contributes to type 2 inflammation and mucus metaplasia during allergic airway disease
Carolyn R. Morris, Aida Habibovic, Christopher M. Dustin, Caspar Schiffers, Miao-Chong Lin, Jennifer L. Ather, Yvonne M.W. Janssen-Heininger, Matthew E. Poynter, Olaf Utermohlen, Martin Krönke, Albert van der Vliet
Mucosal Immunol. Author manuscript; available in PMC 2022 Dec 2.
Published in final edited form as: Mucosal Immunol. 2022 May; 15(5): 977–989. Published online 2022 Jun 2. doi: 10.1038/s41385-022-00530-x
PMCID:
PMC9391268
ArticlePDF–2.2M
5.
Germline saturation mutagenesis induces skeletal phenotypes in mice
Jonathan J Rios, Kristin Denton, Jamie Russell, Julia Kozlitina, Carlos R Ferreira, Amy F Lewanda, Joshua E Mayfield, Eva Moresco, Sara Ludwig, Miao Tang, Xiaohong Li, Stephen Lyon, Anas Khanshour, Nandina Paria, Aysha Khalid, Yang Li, Xudong Xie, Jian Q Feng, Qian Xu, Yongbo Lu, Robert E Hammer, Carol A Wise, Bruce Beutler
J Bone Miner Res. Author manuscript; available in PMC 2022 Aug 1.
Published in final edited form as: J Bone Miner Res. 2021 Aug; 36(8): 1548–1565. Published online 2021 May 10. doi: 10.1002/jbmr.4323
PMCID:
PMC8862308
AbstractArticlePDF–2.5M
6.
Redox-dependent activation of Src kinase mediates epithelial IL-33 production and signaling during acute airway allergen challenge
Christopher M. Dustin, Aida Habibovic, Milena Hristova, Caspar Schiffers, Carolyn R. Morris, Miao-Chong Joy Lin, Robert A. Bauer, David E. Heppner, Nirav Daphtary, Minara Aliyeva, Albert van der Vliet
J Immunol. Author manuscript; available in PMC 2022 Jun 15.
Published in final edited form as: J Immunol. 2021 Jun 15; 206(12): 2989–2999. Published online 2021 Jun 4. doi: 10.4049/jimmunol.2000995
PMCID:
PMC8642476
AbstractArticlePDF–2.0M
7.
Downregulation of DUOX1 function contributes to aging-related impairment of innate airway injury responses and accelerated senile emphysema
Caspar Schiffers, Lennart K. A. Lundblad, Milena Hristova, Aida Habibovic, Christopher M. Dustin, Nirav Daphtary, Minara Aliyeva, David J. Seward, Yvonne M. W. Janssen-Heininger, Emiel F. M. Wouters, Niki L. Reynaert, Albert van der Vliet
Am J Physiol Lung Cell Mol Physiol. 2021 Jul 1; 321(1): L144–L158. Published online 2021 May 5. doi: 10.1152/ajplung.00021.2021
PMCID:
PMC8321859
AbstractArticle
8.
Dual oxidase 1 promotes antiviral innate immunity
Demba Sarr, Aaron D. Gingerich, Nuha Milad Asthiwi, Faris Almutairi, Giuseppe A. Sautto, Jeffrey Ecker, Tamás Nagy, Matthew B. Kilgore, Joshua D. Chandler, Ted M. Ross, Ralph A. Tripp, Balázs Rada
Proc Natl Acad Sci U S A. 2021 Jun 29; 118(26): e2017130118. Published online 2021 Jun 24. doi: 10.1073/pnas.2017130118
Correction in:
Proc Natl Acad Sci U S A. 2021 Dec 7; 118(49): e2119174118.
PMCID:
PMC8256044
AbstractArticlePDF–4.3M
9.
Downregulation of epithelial DUOX1 in chronic obstructive pulmonary disease
Caspar Schiffers, Cheryl van de Wetering, Robert A. Bauer, Aida Habibovic, Milena Hristova, Christopher M. Dustin, Sara Lambrichts, Pamela M. Vacek, Emiel F.M. Wouters, Niki L. Reynaert, Albert van der Vliet
JCI Insight. 2021 Jan 25; 6(2): e142189. Published online 2021 Jan 25. doi: 10.1172/jci.insight.142189
PMCID:
PMC7934842
AbstractArticlePDF–2.9M
10.
Structures of mouse DUOX1–DUOXA1 provide mechanistic insights into enzyme activation and regulation
Ji Sun
Nat Struct Mol Biol. Author manuscript; available in PMC 2021 Mar 14.
Published in final edited form as: Nat Struct Mol Biol. 2020 Nov; 27(11): 1086–1093. Published online 2020 Sep 14. doi: 10.1038/s41594-020-0501-x
PMCID:
PMC7644671
AbstractArticlePDF–6.7M
11.
Neurotoxic Activation of Microglia Is Promoted by a Nox1-Dependent NADPH Oxidase
Cyril Chéret, Annie Gervais, Aurélia Lelli, Catherine Colin, Lahouari Amar, Philippe Ravassard, Jacques Mallet, Ana Cumano, Karl-Heinz Krause, Michel Mallat
J Neurosci. 2008 Nov 12; 28(46): 12039–12051. doi: 10.1523/JNEUROSCI.3568-08.2008
PMCID:
PMC6671643
AbstractArticlePDF–668K
12.
Dual oxidase 1(Duox1) regulates primary B cell function under the influence of IL-4 through BCR-mediated generation of hydrogen peroxide
Ryuichi Sugamata, Agnes Donko, Yousuke Murakami, Howard Boudreau, Chen-Feng Qi, Jaeyul Kwon, Thomas L. Leto
J Immunol. Author manuscript; available in PMC 2020 Jan 15.
Published in final edited form as: J Immunol. 2019 Jan 15; 202(2): 428–440. Published online 2018 Dec 17. doi: 10.4049/jimmunol.1601395
PMCID:
PMC6324942
AbstractArticlePDF–2.0M
13.
Autophagy regulates DUOX1 localization and superoxide production in airway epithelial cells during chronic IL-13 stimulation
John D. Dickinson, Jenea M. Sweeter, Kristi J. Warren, Iman M. Ahmad, Xavier De Deken, Matthew C. Zimmerman, Steven L. Brody
Redox Biol. 2018 Apr; 14: 272–284. Published online 2017 Sep 22. doi: 10.1016/j.redox.2017.09.013
PMCID:
PMC5635347
AbstractArticlePDF–2.0M
14.
Cigarette Smoke Impairs A2A Adenosine Receptor Mediated Wound Repair through Up-regulation of Duox-1 Expression
Zhi Tian, Hui Zhang, Jendayi Dixon, Nicole Traphagen, Todd A. Wyatt, Kusum Kharbanda, Samantha Simet Chadwick, Narasaiah Kolliputi, Diane S. Allen-Gipson
Sci Rep. 2017; 7: 44405. Published online 2017 Mar 24. doi: 10.1038/srep44405
PMCID:
PMC5364501
AbstractArticlePDF–1.7M
15.
The NADPH Oxidases DUOX1 and NOX2 Play Distinct Roles in Redox Regulation of Epidermal Growth Factor Receptor Signaling
David E. Heppner, Milena Hristova, Christopher M. Dustin, Karamatullah Danyal, Aida Habibovic, Albert van der Vliet
J Biol Chem. 2016 Oct 28; 291(44): 23282–23293. Published online 2016 Sep 20. doi: 10.1074/jbc.M116.749028
PMCID:
PMC5087744
AbstractArticlePDF–2.3M
16.
Overexpression of Interleukin-4 in the Thyroid of Transgenic Mice Upregulates the Expression of Duox1 and the Anion Transporter Pendrin
Zineb Eskalli, Younes Achouri, Stephan Hahn, Marie-Christine Many, Julie Craps, Samuel Refetoff, Xiao-Hui Liao, Jacques E. Dumont, Jacqueline Van Sande, Bernard Corvilain, Françoise Miot, Xavier De Deken
Thyroid. 2016 Oct 1; 26(10): 1499–1512. Published online 2016 Oct 1. doi: 10.1089/thy.2016.0106
PMCID:
PMC5067804
AbstractArticlePDF–1.0M
17.
Airway epithelial DUOX1 mediates allergen-induced IL-33 secretion and activation of type 2 immune responses
Milena Hristova, Aida Habibovic, Carmen Veith, Yvonne M.W. Janssen-Heininger, Anne E. Dixon, Miklos Geiszt, Albert van der Vliet
J Allergy Clin Immunol. Author manuscript; available in PMC 2017 May 1.
Published in final edited form as: J Allergy Clin Immunol. 2016 May; 137(5): 1545–1556.e11. Published online 2015 Nov 17. doi: 10.1016/j.jaci.2015.10.003
PMCID:
PMC4860024
AbstractArticlePDF–2.4M
18.
DUOX-Mediated Signaling Is Not Required for LPS-Induced Neutrophilic Response in the Airways
Sandra Chang, Angela Linderholm, Richart Harper
PLoS One. 2015; 10(7): e0131810. Published online 2015 Jul 6. doi: 10.1371/journal.pone.0131810
PMCID:
PMC4493023
AbstractArticlePDF–785K
19.
Identification of DUOX1-dependent redox signaling through protein S-glutathionylation in airway epithelial cells
Milena Hristova, Carmen Veith, Aida Habibovic, Ying-Wai Lam, Bin Deng, Miklos Geiszt, Yvonne M.W. Janssen-Heininger, Albert van der Vliet
Redox Biol. 2014; 2: 436–446. Published online 2014 Jan 15. doi: 10.1016/j.redox.2013.12.030
PMCID:
PMC3949091
AbstractArticlePDF–1.4M
20.
Dual Oxidase Regulates Neutrophil Recruitment in Allergic Airways
Sandra Chang, Angela Linderholm, Lisa Franzi, Nicholas Kenyon, Helmut Grasberger, Richart Harper
Free Radic Biol Med. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Free Radic Biol Med. 2013 Dec; 65: 10.1016/j.freeradbiomed.2013.06.012. Published online 2013 Jun 11. doi: 10.1016/j.freeradbiomed.2013.06.012
PMCID:
PMC3859817
AbstractArticlePDF–1.8M

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