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Items: 1 to 20 of 25

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Chronic UCN2 treatment desensitizes CRHR2 and improves insulin sensitivity
Stephen E. Flaherty, III, Olivier Bezy, Wei Zheng, Dong Yan, Xiangping Li, Srinath Jagarlapudi, Bina Albuquerque, Ryan M. Esquejo, Matthew Peloquin, Meriem Semache, Arturo Mancini, Liya Kang, Doreen Drujan, Susanne B. Breitkopf, John D. Griffin, Pierre M. Jean Beltran, Liang Xue, John Stansfield, Evanthia Pashos, Quazi Shakey, Christian Pehmøller, Mara Monetti, Morris J. Birnbaum, Jean-Philippe Fortin, Zhidan Wu
Nat Commun. 2023; 14: 3953. Published online 2023 Jul 4. doi: 10.1038/s41467-023-39597-w
PMCID:
PMC10319809
AbstractArticlePDF–1.2M
3.
Urocortin 2 promotes hypertrophy and enhances skeletal muscle function through cAMP and insulin/IGF-1 signaling pathways
Natalia Lautherbach, Dawit A.P. Gonçalves, Wilian A. Silveira, Sílvia Paula-Gomes, Rafael Rossi Valentim, Neusa M. Zanon, Marcelo G. Pereira, Elen H. Miyabara, Luiz C.C. Navegantes, Isis C. Kettelhut
Mol Metab. 2022 Jun; 60: 101492. Published online 2022 Apr 4. doi: 10.1016/j.molmet.2022.101492
PMCID:
PMC9035725
AbstractArticlePDF–2.6M
4.
Enhanced pelvic responses to stressors in female CRF-overexpressing mice
M. Million, L. Wang, M. P. Stenzel-Poore, S. C. Coste, P. Q. Yuan, C. Lamy, J. Rivier, T. Buffington, Y. Taché
Am J Physiol Regul Integr Comp Physiol. Author manuscript; available in PMC 2021 Apr 30.
Published in final edited form as: Am J Physiol Regul Integr Comp Physiol. 2007 Apr; 292(4): R1429–R1438. Published online 2006 Dec 28. doi: 10.1152/ajpregu.00626.2006
PMCID:
PMC8086341
AbstractArticlePDF–2.3M
5.
Urocortin 2-Deficient Mice Exhibit Gender-Specific Alterations in Circadian Hypothalamus–Pituitary–Adrenal Axis and Depressive-Like Behavior
Alon Chen, Eric Zorrilla, Sean Smith, David Rousso, Coree Levy, Joan Vaughan, Cindy Donaldson, Amanda Roberts, Kuo-Fen Lee, Wylie Vale
J Neurosci. 2006 May 17; 26(20): 5500–5510. doi: 10.1523/JNEUROSCI.3955-05.2006
PMCID:
PMC6675306
AbstractArticlePDF–5.1M
6.
Urocortin 3 Modulates Social Discrimination Abilities via Corticotropin-Releasing Hormone Receptor Type 2
Jan M. Deussing, Johannes Breu, Claudia Kühne, Magdalena Kallnik, Mirjam Bunck, Lisa Glasl, Yi-Chun Yen, Mathias V. Schmidt, Regine Zurmühlen, Annette M. Vogl, Valérie Gailus-Durner, Helmut Fuchs, Sabine M. Hölter, Carsten T. Wotjak, Rainer Landgraf, Martin Hrabé de Angelis, Florian Holsboer, Wolfgang Wurst
J Neurosci. 2010 Jul 7; 30(27): 9103–9116. doi: 10.1523/JNEUROSCI.1049-10.2010
PMCID:
PMC6632482
AbstractArticlePDF–3.0M
7.
IRF3 is an important molecule in the UII/UT system and mediates immune inflammatory injury in acute liver failure
Liang-ming Liu, Wen-juan Tu, Tong Zhu, Xiao-ting Wang, Zhi-li Tan, Huan Zhong, De-yong Gao, Dong-yu Liang
Oncotarget. 2016 Aug 2; 7(31): 49027–49041. Published online 2016 Jul 19. doi: 10.18632/oncotarget.10717
PMCID:
PMC5226488
AbstractArticlePDF–3.1M
8.
One-time injection of AAV8 encoding urocortin 2 provides long-term resolution of insulin resistance
Mei Hua Gao, Dimosthenis Giamouridis, N. Chin Lai, Evelyn Walenta, Vivian Almeida Paschoal, Young Chul Kim, Atsushi Miyanohara, Tracy Guo, Min Liao, Li Liu, Zhen Tan, Theodore P. Ciaraldi, Simon Schenk, Aditi Bhargava, Da Young Oh, H. Kirk Hammond
JCI Insight. 2016 Sep 22; 1(15): e88322. Published online 2016 Sep 22. doi: 10.1172/jci.insight.88322
PMCID:
PMC5033760
AbstractArticlePDF–982K
9.
Effects of urotensin-II on cytokines in early acute liver failure in mice
Liang-Ming Liu, Liang Zhao, Dong-Yu Liang, Fang-Ping Yu, Chang-Gen Ye, Wen-Juan Tu, Tong Zhu
World J Gastroenterol. 2015 Mar 21; 21(11): 3239–3244. Published online 2015 Mar 21. doi: 10.3748/wjg.v21.i11.3239
PMCID:
PMC4363753
AbstractArticlePDF–872K
10.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
11.
Urocortin 2 autocrine/paracrine and pharmacologic effects to activate AMP-activated protein kinase in the heart
Ji Li, Dake Qi, Haiying Cheng, Xiaoyue Hu, Edward J. Miller, Xiaohong Wu, Kerry S. Russell, Nicole Mikush, Jiasheng Zhang, Lei Xiao, Robert S. Sherwin, Lawrence H. Young
Proc Natl Acad Sci U S A. 2013 Oct 1; 110(40): 16133–16138. Published online 2013 Sep 16. doi: 10.1073/pnas.1312775110
PMCID:
PMC3791748
AbstractArticlePDF–990K
12.
Inhibition of UII/UTR System Relieves Acute Inflammation of Liver through Preventing Activation of NF-κB Pathway in ALF Mice
Dong-yu Liang, Liang-ming Liu, Chang-gen Ye, Liang Zhao, Fang-ping Yu, De-yong Gao, Ying-ying Wang, Zhi-wen Yang, Yan-yan Wang
PLoS One. 2013; 8(6): e64895. Published online 2013 Jun 3. doi: 10.1371/journal.pone.0064895
PMCID:
PMC3670940
AbstractArticlePDF–4.8M
13.
Posttranslational Processing of Human and Mouse Urocortin 2: Characterization and Bioactivity of Gene Products
Joan M. Vaughan, Cynthia J. Donaldson, Wolfgang H. Fischer, Marilyn H. Perrin, Jean E. Rivier, Paul E. Sawchenko, Wylie W. Vale
Endocrinology. 2013 Apr; 154(4): 1553–1564. Published online 2013 Mar 14. doi: 10.1210/en.2012-2011
PMCID:
PMC3602626
AbstractArticle
14.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
15.
Systemic urocortin 2, but not urocortin 1 or stressin1-A, suppresses feeding via CRF2 receptors without malaise and stress
ÉM Fekete, Y Zhao, A Szücs, V Sabino, P Cottone, J Rivier, WW Vale, GF Koob, EP Zorrilla
Br J Pharmacol. 2011 Dec; 164(8): 1959–1975. doi: 10.1111/j.1476-5381.2011.01512.x
PMCID:
PMC3246660
AbstractArticlePDF–1.8M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
A triple urocortin knockout mouse model reveals an essential role for urocortins in stress recovery
Adi Neufeld-Cohen, Michael M. Tsoory, Andrew K. Evans, Dmitriy Getselter, Shosh Gil, Christopher A. Lowry, Wylie W. Vale, Alon Chen
Proc Natl Acad Sci U S A. 2010 Nov 2; 107(44): 19020–19025. Published online 2010 Oct 11. doi: 10.1073/pnas.1013761107
PMCID:
PMC2973872
AbstractArticlePDF–483K
18.
Urocortin2 inhibits tumor growth via effects on vascularization and cell proliferation
Zhengrong Hao, Yan Huang, Jake Cleman, Ion S. Jovin, Wylie W. Vale, Tracy L. Bale, Frank J. Giordano
Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10): 3939–3944. Published online 2008 Feb 28. doi: 10.1073/pnas.0712366105
PMCID:
PMC2268793
AbstractArticlePDF–1.0M
19.
Urocortin 2 modulates glucose utilization and insulin sensitivity in skeletal muscle
Alon Chen, Bhawanjit Brar, Cheol Soo Choi, David Rousso, Joan Vaughan, Yael Kuperman, Shee Ne Kim, Cindy Donaldson, Sean M. Smith, Pauline Jamieson, Chien Li, Tim R. Nagy, Gerald I. Shulman, Kuo-Fen Lee, Wylie Vale
Proc Natl Acad Sci U S A. 2006 Oct 31; 103(44): 16580–16585. Published online 2006 Oct 18. doi: 10.1073/pnas.0607337103
PMCID:
PMC1637624
AbstractArticlePDF–1013K
20.
BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System
Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran
PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086
PMCID:
PMC1413568
ArticlePDF–99K

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