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Select item 93716801.

Fic-mediated AMPylation tempers the unfolded protein response during physiological stress

Amanda K. Casey, Hillery F. Gray, Suneeta Chimalapati, Genaro Hernandez, Andrew T. Moehlman, Nathan Stewart, Hazel A. Fields, Burak Gulen, Kelly A. Servage, Karoliina Stefanius, Aubrie Blevins, Bret M. Evers, Helmut Krämer, Kim Orth

Proc Natl Acad Sci U S A. 2022 Aug 9; 119(32): e2208317119. Published online 2022 Aug 1. doi: 10.1073/pnas.2208317119

PMCID:: PMC9371680

Abstract Article PDF–1.2M

Select item 84688272.

Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders

Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D’Avino, Maria Grazia Giansanti

Cells. 2021 Sep; 10(9): 2336. Published online 2021 Sep 6. doi: 10.3390/cells10092336

PMCID:: PMC8468827

Abstract Article PDF–4.1M

Select item 69615783.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 60663274.

Adaptation to constant light requires Fic-mediated AMPylation of BiP to protect against reversible photoreceptor degeneration

Andrew T Moehlman, Amanda K Casey, Kelly Servage, Kim Orth, Helmut Krämer

eLife. 2018; 7: e38752. Published online 2018 Jul 17. doi: 10.7554/eLife.38752

PMCID:: PMC6066327

Abstract Article PDF–4.2M

Select item 57430915.

Fic-mediated deAMPylation is not dependent on homodimerization and rescues toxic AMPylation in flies

Amanda K. Casey, Andrew T. Moehlman, Junmei Zhang, Kelly A. Servage, Helmut Krämer, Kim Orth

J Biol Chem. 2017 Dec 22; 292(51): 21193–21204. Published online 2017 Oct 31. doi: 10.1074/jbc.M117.799296

Correction in:: J Biol Chem. 2018 Feb 2; 293(5): 1550.

PMCID:: PMC5743091

Abstract Article PDF–1.6M

Select item 57078056.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 56890027.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 48896588.

mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster

Gildas Lepennetier, Francesco Catania

G3 (Bethesda) 2016 Jun; 6(6): 1617–1626. Published online 2016 Mar 28. doi: 10.1534/g3.116.029231

PMCID:: PMC4889658

Abstract Article PDF–1.5M

Select item 45283309.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832910.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 435288711.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

Select item 427687112.

Unfolded Protein Response-regulated Drosophila Fic (dFic) Protein Reversibly AMPylates BiP Chaperone during Endoplasmic Reticulum Homeostasis

Hyeilin Ham, Andrew R. Woolery, Charles Tracy, Drew Stenesen, Helmut Krämer, Kim Orth

J Biol Chem. 2014 Dec 26; 289(52): 36059–36069. Published online 2014 Nov 13. doi: 10.1074/jbc.M114.612515

PMCID:: PMC4276871

Abstract Article PDF–1.6M

Select item 414064213.

Wnt-Mediated Repression via Bipartite DNA Recognition by TCF in the Drosophila Hematopoietic System

Chen U. Zhang, Timothy A. Blauwkamp, Peter E. Burby, Ken M. Cadigan

PLoS Genet. 2014 Aug; 10(8): e1004509. Published online 2014 Aug 21. doi: 10.1371/journal.pgen.1004509

PMCID:: PMC4140642

Abstract Article PDF–2.0M

Select item 357855414.

Visual neurotransmission in Drosophila requires expression of Fic in glial capitate projections

Mokhlasur Rahman, Hyeilin Ham, Xinran Liu, Yoshie Sugiura, Kim Orth, Helmut Krämer

Nat Neurosci. Author manuscript; available in PMC 2013 Feb 21.

Published in final edited form as: Nat Neurosci. 2012 Jun; 15(6): 871–875. doi: 10.1038/nn.3102

PMCID:: PMC3578554

Abstract Article PDF–2.3M

Select item 353067715.

High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression

Philippe Batut, Alexander Dobin, Charles Plessy, Piero Carninci, Thomas R. Gingeras

Genome Res. 2013 Jan; 23(1): 169–180. doi: 10.1101/gr.139618.112

PMCID:: PMC3530677

Abstract Article PDF–1.5M

Select item 346946716.

The Many Landscapes of Recombination in Drosophila melanogaster

Josep M. Comeron, Ramesh Ratnappan, Samuel Bailin

PLoS Genet. 2012 Oct; 8(10): e1002905. Published online 2012 Oct 11. doi: 10.1371/journal.pgen.1002905

PMCID:: PMC3469467

Abstract Article PDF–1.6M

Select item 315349717.

Division of labor: Subsets of dorsal-appendage-forming cells control the shape of the entire tube

Michael J. Boyle, Rachael L. French, K. Amber Cosand, Jennie B. Dorman, Daniel P. Kiehart, Celeste A. Berg

Dev Biol. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: Dev Biol. 2010 Oct 1; 346(1): 68–79. Published online 2010 Jul 24. doi: 10.1016/j.ydbio.2010.07.018

PMCID:: PMC3153497

Abstract Article PDF–2.1M

Select item 305141718.

Two-color in vivo imaging of photoreceptor apoptosis and development in Drosophila

Alexis Gambis, Pierre Dourlen, Hermann Steller, Bertrand Mollereau

Dev Biol. Author manuscript; available in PMC 2011 Sep 1.

Published in final edited form as: Dev Biol. 2011 Mar 1; 351(1): 128–134. Published online 2011 Jan 4. doi: 10.1016/j.ydbio.2010.12.040

PMCID:: PMC3051417

Abstract Article PDF–2.0M

Select item 304044119.

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionary-conserved pain gene

G. Gregory Neely, Andreas Hess, Michael Costigan, Alex C. Keene, Spyros Goulas, Michiel Langeslag, Robert S Griffin, Inna Belfer, Feng Dai, Shad Smith, Luda Diatchenko, Vaijayanti Gupta, Cui-ping Xia, Sabina Amann, Silke Kreitz, Cornelia Heindl-Erdmann, Susanne Wolz, Cindy V. Ly, Suchir Arora, Rinku Sarangi, Debasis Dan, Maria Novatchkova, Mark Rosenzweig, Dustin Gibson, Darwin Truong, Daniel Schramek, Tamara Zoranovic, Shane J. F. Cronin, Belinda Angjeli, Kay Brune, Georg Dietzl, William Maixner, Arabella Meixner, Winston Thomas, J. Andrew Pospisilik, Mattias Alenius, Michaela Kress, Sai Subramaniam, Paul A. Garrity, Hugo J. Bellen, Clifford J. Woolf, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Nov 12.

Published in final edited form as: Cell. 2010 Nov 12; 143(4): 628–638. doi: 10.1016/j.cell.2010.09.047

PMCID:: PMC3040441

Abstract Article PDF–2.0M

Select item 285522120.

A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function

G. Gregory Neely, Keiji Kuba, Anthony Cammarato, Kazuya Isobe, Sabine Amann, Liyong Zhang, Mitsushige Murata, Lisa Elmén, Vaijayanti Gupta, Suchir Arora, Rinku Sarangi, Debasis Dan, Susumu Fujisawa, Takako Usami, Cui-ping Xia, Alex C. Keene, Nakissa N. Alayari, Hiroyuki Yamakawa, Ulrich Elling, Christian Berger, Maria Novatchkova, Rubina Koglgruber, Keiichi Fukuda, Hiroshi Nishina, Mitsuaki Isobe, J. Andrew Pospisilik, Yumiko Imai, Arne Pfeufer, Andrew A Hicks, Peter P. Pramstaller, Sai Subramaniam, Akinori Kimura, Karen Ocorr, Rolf Bodmer, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Apr 2.

Published in final edited form as: Cell. 2010 Apr 2; 141(1): 142–153. doi: 10.1016/j.cell.2010.02.023

PMCID:: PMC2855221

Abstract Article PDF–5.3M

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