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Select item 106407611.

Infiltrating myeloid cell-derived properdin markedly promotes microglia-mediated neuroinflammation after ischemic stroke

Pin-yi Liu, Hui-qin Li, Meng-qi Dong, Xin-ya Gu, Si-yi Xu, Sheng-nan Xia, Xin-yu Bao, Yun Xu, Xiang Cao

J Neuroinflammation. 2023; 20: 260. Published online 2023 Nov 11. doi: 10.1186/s12974-023-02946-z

PMCID:: PMC10640761

Abstract Article PDF–11M

Select item 101914412.

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities

Chao Liu, Lingang Sun, Yijun Tan, Qi Wang, Tao Luo, Chenlu Li, Nan Yao, Yuting Xie, Xiao Yi, Yi Zhu, Tiannan Guo, Junfeng Ji

Sci Adv. 2023 May; 9(20): eade3888. Published online 2023 May 17. doi: 10.1126/sciadv.ade3888

PMCID:: PMC10191441

Abstract Article PDF–2.4M

Select item 101889973.

HBSP improves kidney ischemia-reperfusion injury and promotes repair in properdin deficient mice via enhancing phagocytosis of tubular epithelial cells

Yuanyuan Wu, Lili Huang, Wenli Sai, Fei Chen, Yu Liu, Cheng Han, Joanna M. Barker, Zinah D. Zwaini, Mark P. Lowe, Nigel J. Brunskill, Bin Yang

Front Immunol. 2023; 14: 1183768. Published online 2023 May 3. doi: 10.3389/fimmu.2023.1183768

Correction in:: Front Immunol. 2023; 14: 1242436.

PMCID:: PMC10188997

Abstract Article PDF–5.9M

Select item 99684104.

Neutrophil-activating therapy for the treatment of cancer

Ian L. Linde, Tyler R. Prestwood, Jingtao Qiu, Genay Pilarowski, Miles H. Linde, Xiangyue Zhang, Lei Shen, Nathan E. Reticker-Flynn, David Kung-Chun Chiu, Lauren Y. Sheu, Simon Van Deursen, Lorna L. Tolentino, Wen-Chao Song, Edgar G. Engleman

Cancer Cell. Author manuscript; available in PMC 2024 Feb 13.

Published in final edited form as: Cancer Cell. 2023 Feb 13; 41(2): 356–372.e10. Published online 2023 Jan 26. doi: 10.1016/j.ccell.2023.01.002

PMCID:: PMC9968410

Abstract Article PDF–4.0M

Select item 84505665.

Properdin Deficiency Impairs Phagocytosis and Enhances Injury at Kidney Repair Phase Post Ischemia–Reperfusion

Yuanyuan Wu, Zinah D. Zwaini, Nigel J. Brunskill, Xinyue Zhang, Hui Wang, Ravinder Chana, Cordula M. Stover, Bin Yang

Front Immunol. 2021; 12: 697760. Published online 2021 Sep 6. doi: 10.3389/fimmu.2021.697760

PMCID:: PMC8450566

Abstract Article PDF–14M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 75593327.

Complement Properdin Determines Disease Activity in MRL/lpr Mice

Hasanain Alaridhee, Azzah Alharbi, Zeayd Saeed, Róisín C. Thomas, Cordula M. Stover

Medicina (Kaunas) 2020 Sep; 56(9): 430. Published online 2020 Aug 27. doi: 10.3390/medicina56090430

PMCID:: PMC7559332

Abstract Article PDF–1.9M

Select item 60650808.

Prevention of Fatal C3 Glomerulopathy by Recombinant Complement Receptor of the Ig Superfamily

Xiaoxu Wang, Menno Van Lookeren Campagne, Kenneth J. Katschke, Jr., Damodar Gullipalli, Takashi Miwa, Yoshiyasu Ueda, Yuan Wang, Matthew Palmer, Guolan Xing, Wen-Chao Song

J Am Soc Nephrol. 2018 Aug; 29(8): 2053–2059. Published online 2018 Jun 12. doi: 10.1681/ASN.2018030270

PMCID:: PMC6065080

Abstract Article

Select item 60578079.

Antibody inhibition of properdin prevents complement-mediated intravascular and extravascular hemolysis¹

Damodar Gullipalli, Fengkui Zhang, Sayaka Sato, Yoshiyasu Ueda, Yuko Kimura, Mahdu Golla, Takashi Miwa, Jianxiang Wang, Wen-Chao Song

J Immunol. Author manuscript; available in PMC 2019 Aug 1.

Published in final edited form as: J Immunol. 2018 Aug 1; 201(3): 1021–1029. Published online 2018 Jun 13. doi: 10.4049/jimmunol.1800384

PMCID:: PMC6057807

Abstract Article PDF–712K

Select item 605094110.

Blocking Properdin Prevents Complement-Mediated Hemolytic Uremic Syndrome and Systemic Thrombophilia

Yoshiyasu Ueda, Takashi Miwa, Damodar Gullipalli, Sayaka Sato, Daisuke Ito, Hangsoo Kim, Matthew Palmer, Wen-Chao Song

J Am Soc Nephrol. 2018 Jul; 29(7): 1928–1937. Published online 2018 Jun 1. doi: 10.1681/ASN.2017121244

PMCID:: PMC6050941

Abstract Article

Select item 604023611.

Retinal Basal Laminar Deposits in Complement fH/fP Mouse Model of Dense Deposit Disease

Delu Song, Imran Mohammed, Rupak Bhuyan, Takashi Miwa, Allison Lesher Williams, Damodar Gullipalli, Sayaka Sato, Ying Song, Joshua L. Dunaief, Wen-Chao Song

Invest Ophthalmol Vis Sci. 2018 Jul; 59(8): 3405–3415. doi: 10.1167/iovs.18-24133

PMCID:: PMC6040236

Abstract Article PDF–1.8M

Select item 589342412.

Contribution of Adipose-derived Factor D/Adipsin to Alternative Pathway Complement Activation: Lessons from Lipodystrophy

Xiaobo Wu, Irina Hutson, Antonina M. Akk, Smita Mascharak, Christine T.N. Pham, Dennis E. Hourcade, Rebecca Brown, John P. Atkinson, Charles A. Harris

J Immunol. Author manuscript; available in PMC 2019 Apr 15.

Published in final edited form as: J Immunol. 2018 Apr 15; 200(8): 2786–2797. Published online 2018 Mar 12. doi: 10.4049/jimmunol.1701668

PMCID:: PMC5893424

Abstract Article PDF–4.5M

Select item 534336813.

Properdin deficiency protects from 5‐fluorouracil‐induced small intestinal mucositis in a complement activation‐independent, interleukin‐10‐dependent mechanism

U. Jain, C. A. Midgen, T. M. Woodruff, W. J. Schwaeble, C. M. Stover, A. W. Stadnyk

Clin Exp Immunol. 2017 Apr; 188(1): 36–44. Published online 2017 Jan 31. doi: 10.1111/cei.12922

PMCID:: PMC5343368

Abstract Article PDF–489K

Select item 532216414.

Tumour cell conditioned medium reveals greater M2 skewing of macrophages in the absence of properdin

Izzat A.M. Al‐Rayahi, Michael J. Browning, Cordula Stover

Immun Inflamm Dis. 2017 Mar; 5(1): 68–77. Published online 2017 Jan 26. doi: 10.1002/iid3.142

PMCID:: PMC5322164

Abstract Article PDF–3.8M

Select item 499633815.

Experimentally‐induced anti‐myeloperoxidase vasculitis does not require properdin, MASP‐2 or bone marrow‐derived C5

Simon J Freeley, Reena J Popat, Kiran Parmar, Martin Kolev, Beverley J Hunt, Cordula M Stover, Willhelm Schwaeble, Claudia Kemper, Michael G Robson

J Pathol. 2016 Sep; 240(1): 61–71. Published online 2016 Aug 22. doi: 10.1002/path.4754

Correction in:: J Pathol. 2021 May; 254(1): 103.

PMCID:: PMC4996338

Abstract Article PDF–5.3M

Select item 497366016.

The Complement Regulatory Protein CD46 Deficient Mouse Spontaneously Develops Dry-Type Age-Related Macular Degeneration–Like Phenotype

Valeriy V. Lyzogubov, Puran S. Bora, Xiaobo Wu, Leah E. Horn, Ryan de Roque, Xeniya V. Rudolf, John P. Atkinson, Nalini S. Bora

Am J Pathol. 2016 Aug; 186(8): 2088–2104. doi: 10.1016/j.ajpath.2016.03.021

PMCID:: PMC4973660

Abstract Article PDF–4.3M

Select item 450688017.

Properdin contributes to allergic airway inflammation through local C3a generation

Yuan Wang, Takashi Miwa, Blerina Ducka-Kokalari, Imre G. Redai, Sayaka Sato, Damodar Gullipalli, James G. Zangrilli, Angela Haczku, Wen-Chao Song

J Immunol. Author manuscript; available in PMC 2016 Aug 1.

Published in final edited form as: J Immunol. 2015 Aug 1; 195(3): 1171–1181. Published online 2015 Jun 26. doi: 10.4049/jimmunol.1401819

PMCID:: PMC4506880

Abstract Article PDF–1.8M

Select item 411803918.

Septicaemia models using Streptococcus pneumoniae and Listeria monocytogenes: understanding the role of complement properdin

Aline Dupont, Fatima Mohamed, Nur’Ain Salehen, Sarah Glenn, Lorenza Francescut, Rozita Adib, Simon Byrne, Hannah Brewin, Irina Elliott, Luke Richards, Petya Dimitrova, Wilhelm Schwaeble, Nina Ivanovska, Aras Kadioglu, Lee R. Machado, Peter W. Andrew, Cordula Stover

Med Microbiol Immunol. 2014; 203(4): 257–271. Published online 2014 Apr 12. doi: 10.1007/s00430-013-0324-z

PMCID:: PMC4118039

Abstract Article PDF–2.8M

Select item 398614119.

Low-dose recombinant properdin provides substantial protection against Streptococcus pneumoniae and Neisseria meningitidis infection

Youssif Mohammed Ali, Azam Hayat, Bayad Mawlood Saeed, Kashif S. Haleem, Saleh Alshamrani, Hany I. Kenawy, Viviana P. Ferreira, Gurpanna Saggu, Anna Buchberger, Peter J. Lachmann, Robert B. Sim, Dimitrios Goundis, Peter W. Andrew, Nicholas J. Lynch, Wilhelm J. Schwaeble

Proc Natl Acad Sci U S A. 2014 Apr 8; 111(14): 5301–5306. Published online 2014 Mar 24. doi: 10.1073/pnas.1401011111

PMCID:: PMC3986141

Abstract Article PDF–789K

Select item 396542320.

Protective Role for Properdin in Progression of Experimental Murine Atherosclerosis

Tanja Steiner, Lorenza Francescut, Simon Byrne, Timothy Hughes, Archana Jayanthi, Irina Guschina, John Harwood, Katherine Cianflone, Cordula Stover, Sheila Francis

PLoS One. 2014; 9(3): e92404. Published online 2014 Mar 25. doi: 10.1371/journal.pone.0092404

PMCID:: PMC3965423

Abstract Article PDF–1.0M

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