U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO Profiles

Items: 1 to 20 of 63

1.
Effects of glucokinase haploinsufficiency on the pancreatic β‐cell mass and function of long‐term high‐fat, high‐sucrose diet‐fed mice
Ikumi Shigesawa, Akinobu Nakamura, Yuki Yamauchi, Shinichiro Kawata, Asuka Miyazaki, Hiroshi Nomoto, Hiraku Kameda, Yasuo Terauchi, Tatsuya Atsumi
J Diabetes Investig. 2024 Dec; 15(12): 1732–1742. Published online 2024 Sep 21. doi: 10.1111/jdi.14307
PMCID:
PMC11615693
AbstractArticlePDF–6.5M
2.
Reducing Oxidative Stress and Inflammation by Pyruvate Dehydrogenase Kinase 4 Inhibition Is Important in Prevention of Renal Ischemia-Reperfusion Injury in Diabetic Mice
Ah Reum Khang, Dong Hun Kim, Min-Ji Kim, Chang Joo Oh, Jae-Han Jeon, Sung Hee Choi, In-Kyu Lee
Diabetes Metab J. 2024 May; 48(3): 405–417. Published online 2024 Feb 1. doi: 10.4093/dmj.2023.0196
PMCID:
PMC11140394
AbstractArticlePDF–3.8M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
Lung dendritic-cell metabolism underlies susceptibility to viral infection in diabetes
Samuel Philip Nobs, Aleksandra A. Kolodziejczyk, Lital Adler, Nir Horesh, Christine Botscharnikow, Ella Herzog, Gayatree Mohapatra, Sophia Hejndorf, Ryan-James Hodgetts, Igor Spivak, Lena Schorr, Leviel Fluhr, Denise Kviatcovsky, Anish Zacharia, Suzanne Njuki, Dinorah Barasch, Noa Stettner, Mally Dori-Bachash, Alon Harmelin, Alexander Brandis, Tevie Mehlman, Ayelet Erez, Yiming He, Sara Ferrini, Jens Puschhof, Hagit Shapiro, Manfred Kopf, Arieh Moussaieff, Suhaib K. Abdeen, Eran Elinav
Nature. 2023; 624(7992): 645–652. Published online 2023 Dec 13. doi: 10.1038/s41586-023-06803-0
PMCID:
PMC10733144
AbstractArticlePDF–13M
5.
Glucose Controls Glucagon Secretion by Regulating Fatty Acid Oxidation in Pancreatic α-Cells
Sarah L. Armour, Alexander Frueh, Margarita V. Chibalina, Haiqiang Dou, Lidia Argemi-Muntadas, Alexander Hamilton, Georgios Katzilieris-Petras, Peter Carmeliet, Benjamin Davies, Thomas Moritz, Lena Eliasson, Patrik Rorsman, Jakob G. Knudsen
Diabetes. 2023 Oct; 72(10): 1446–1459. Published online 2023 Jul 26. doi: 10.2337/db23-0056
PMCID:
PMC10545563
AbstractArticlePDF–56M
6.
Glucocorticoid Receptors Drive Breast Cancer Cell Migration and Metabolic Reprogramming via PDK4
Amy R Dwyer, Carlos Perez Kerkvliet, Thu H Truong, Kyla M Hagen, Raisa I Krutilina, Deanna N Parke, Robert H Oakley, Christopher Liddle, John A Cidlowski, Tiffany N Seagroves, Carol A Lange
Endocrinology. 2023 Jul; 164(7): bqad083. Published online 2023 May 24. doi: 10.1210/endocr/bqad083
Correction in:
Endocrinology. 2023 Aug; 164(8): bqad101.
PMCID:
PMC10251300
AbstractArticle
7.
Cardiomyocyte Pdk4 response is associated with metabolic maladaptation in aging
Mohammad Kasim Fatmi, Di Ren, Julia Fedorova, Linda Ines Zoungrana, Hao Wang, Kayla Davitt, Zehui Li, Migdalia Iglesias, Edward J. Lesnefsky, Meredith Krause‐Hauch, Ji Li
Aging Cell. 2023 Apr; 22(4): e13800. Published online 2023 Feb 16. doi: 10.1111/acel.13800
PMCID:
PMC10086528
AbstractArticlePDF–7.0M
8.
Enhanced Ca2+-channeling complex formation at the ER-mitochondria interface underlies the pathogenesis of alcohol-associated liver disease
Themis Thoudam, Dipanjan Chanda, Jung Yi Lee, Min-Kyo Jung, Ibotombi Singh Sinam, Byung-Gyu Kim, Bo-Yoon Park, Woong Hee Kwon, Hyo-Jeong Kim, Myeongjin Kim, Chae Won Lim, Hoyul Lee, Yang Hoon Huh, Caroline A. Miller, Romil Saxena, Nicholas J. Skill, Nazmul Huda, Praveen Kusumanchi, Jing Ma, Zhihong Yang, Min-Ji Kim, Ji Young Mun, Robert A. Harris, Jae-Han Jeon, Suthat Liangpunsakul, In-Kyu Lee
Nat Commun. 2023; 14: 1703. Published online 2023 Mar 27. doi: 10.1038/s41467-023-37214-4
PMCID:
PMC10042999
AbstractArticlePDF–12M
9.
Pyruvate dehydrogenase kinase 4 promotes ubiquitin–proteasome system‐dependent muscle atrophy
Ibotombi Singh Sinam, Dipanjan Chanda, Themis Thoudam, Min‐Ji Kim, Byung‐Gyu Kim, Hyeon‐Ji Kang, Jung Yi Lee, Seung‐Hoon Baek, Shin‐Yoon Kim, Bum Jin Shim, Dongryeol Ryu, Jae‐Han Jeon, In‐Kyu Lee
J Cachexia Sarcopenia Muscle. 2022 Dec; 13(6): 3122–3136. Published online 2022 Oct 19. doi: 10.1002/jcsm.13100
Correction in:
J Cachexia Sarcopenia Muscle. 2023 Jun; 14(3): 1585.
Correction in:
J Cachexia Sarcopenia Muscle. 2023 Oct; 14(5): 2455.
PMCID:
PMC9745560
AbstractArticlePDF–2.6M
10.
Sex differences in metabolic pathways are regulated by Pfkfb3 and Pdk4 expression in rodent muscle
Antonius Christianto, Takashi Baba, Fumiya Takahashi, Kai Inui, Miki Inoue, Mikita Suyama, Yusuke Ono, Yasuyuki Ohkawa, Ken-ichirou Morohashi
Commun Biol. 2021; 4: 1264. Published online 2021 Nov 4. doi: 10.1038/s42003-021-02790-y
PMCID:
PMC8569015
AbstractArticlePDF–1.5M
11.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
12.
PPARδ and FOXO1 Mediate Palmitate-Induced Inhibition of Muscle Pyruvate Dehydrogenase Complex and CHO Oxidation, Events Reversed by Electrical Pulse Stimulation
Hung-Che Chien, Paul L. Greenhaff, Dumitru Constantin-Teodosiu
Int J Mol Sci. 2020 Aug; 21(16): 5942. Published online 2020 Aug 18. doi: 10.3390/ijms21165942
PMCID:
PMC7460628
AbstractArticlePDF–2.3M
13.
A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation
Tomoya Sakamoto, Timothy R. Matsuura, Shibiao Wan, David M. Ryba, Junil Kim, Kyoung Jae Won, Ling Lai, Christopher Petucci, Nataliya Petrenko, Kiran Musunuru, Rick B. Vega, Daniel P. Kelly
Circ Res. Author manuscript; available in PMC 2021 Jun 5.
Published in final edited form as: Circ Res. 2020 Jun 5; 126(12): 1685–1702. Published online 2020 Mar 26. doi: 10.1161/CIRCRESAHA.119.316100
PMCID:
PMC7274895
AbstractArticlePDF–2.7M
14.
Reactive oxygen species-dependent regulation of pyruvate dehydrogenase kinase-4 in white adipose tissue
Logan K. Townsend, Alyssa J. Weber, Pierre-Andre Barbeau, Graham P. Holloway, David C. Wright
Am J Physiol Cell Physiol. 2020 Jan 1; 318(1): C137–C149. Published online 2019 Nov 13. doi: 10.1152/ajpcell.00313.2019
PMCID:
PMC6985839
AbstractArticle
15.
Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function
Nora Yucel, Yu Xin Wang, Thach Mai, Ermelinda Porpiglia, Peder J. Lund, Glenn Markov, Benjamin A. Garcia, Sean C. Bendall, Michael Angelo, Helen M. Blau
Cell Rep. Author manuscript; available in PMC 2019 Oct 11.
Published in final edited form as: Cell Rep. 2019 Jun 25; 27(13): 3939–3955.e6. doi: 10.1016/j.celrep.2019.05.092
PMCID:
PMC6788807
AbstractArticlePDF–2.3M
16.
Metabolic Connection of Inflammatory Pain: Pivotal Role of a Pyruvate Dehydrogenase Kinase-Pyruvate Dehydrogenase-Lactic Acid Axis
Mithilesh Kumar Jha, Gyun Jee Song, Maan Gee Lee, Nam Ho Jeoung, Younghoon Go, Robert A. Harris, Dong Ho Park, Hyun Kook, In-Kyu Lee, Kyoungho Suk
J Neurosci. 2015 Oct 21; 35(42): 14353–14369. doi: 10.1523/JNEUROSCI.1910-15.2015
PMCID:
PMC6605420
AbstractArticlePDF–5.5M
17.
Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells
Keiyo Takubo, Go Nagamatsu, Chiharu I. Kobayashi, Ayako Nakamura-Ishizu, Hiroshi Kobayashi, Eiji Ikeda, Nobuhito Goda, Yasmeen Rahimi, Randall S. Johnson, Tomoyoshi Soga, Atsushi Hirao, Makoto Suematsu, Toshio Suda
Cell Stem Cell. Author manuscript; available in PMC 2019 Jun 25.
Published in final edited form as: Cell Stem Cell. 2013 Jan 3; 12(1): 49–61. doi: 10.1016/j.stem.2012.10.011
PMCID:
PMC6592822
AbstractArticlePDF–2.5M
18.
PDK4 drives metabolic alterations and muscle atrophy in cancer cachexia
Fabrizio Pin, Leah J. Novinger, Joshua R. Huot, Robert A. Harris, Marion E. Couch, Thomas M. O’Connell, Andrea Bonetto
FASEB J. 2019 Jun; 33(6): 7778–7790. Published online 2019 Mar 20. doi: 10.1096/fj.201802799R
PMCID:
PMC6529344
AbstractArticle
19.
Pyruvate Dehydrogenase Kinase Is a Metabolic Checkpoint for Polarization of Macrophages to the M1 Phenotype
Byong-Keol Min, Sungmi Park, Hyeon-Ji Kang, Dong Wook Kim, Hye Jin Ham, Chae-Myeong Ha, Byung-Jun Choi, Jung Yi Lee, Chang Joo Oh, Eun Kyung Yoo, Hui Eon Kim, Byung-Gyu Kim, Jae-Han Jeon, Do Young Hyeon, Daehee Hwang, Yong-Hoon Kim, Chul-Ho Lee, Taeho Lee, Jung-whan Kim, Yeon-Kyung Choi, Keun-Gyu Park, Ajay Chawla, Jongsoon Lee, Robert A. Harris, In-Kyu Lee
Front Immunol. 2019; 10: 944. Published online 2019 May 7. doi: 10.3389/fimmu.2019.00944
PMCID:
PMC6514528
AbstractArticlePDF–9.8M
20.
PDK4 Augments ER–Mitochondria Contact to Dampen Skeletal Muscle Insulin Signaling During Obesity
Themis Thoudam, Chae-Myeong Ha, Jaechan Leem, Dipanjan Chanda, Jong-Seok Park, Hyo-Jeong Kim, Jae-Han Jeon, Yeon-Kyung Choi, Suthat Liangpunsakul, Yang Hoon Huh, Tae-Hwan Kwon, Keun-Gyu Park, Robert A. Harris, Kyu-Sang Park, Hyun-Woo Rhee, In-Kyu Lee
Diabetes. 2019 Mar; 68(3): 571–586. Published online 2018 Dec 6. doi: 10.2337/db18-0363
PMCID:
PMC6385748
AbstractArticlePDF–3.7M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

You are here: NCBI > Literature > PubMed Central (PMC)
Support Center