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Select item 111663711.

Enhanced TRPC3 transcription through AT1R/PKA/CREB signaling contributes to mitochondrial dysfunction in renal tubular epithelial cells in D‐galactose‐induced accelerated aging mice

Bin Wang, Wenpei Yu, Weiguang Zhang, Min Zhang, Yue Niu, Xinye Jin, Jie Zhang, Ding Sun, Hao Li, Zehao Zhang, Qing Luo, Xiaowei Cheng, Jingxue Niu, Guangyan Cai, Xiangmei Chen, Yizhi Chen

Aging Cell. 2024 Jun; 23(6): e14130. Published online 2024 Feb 28. doi: 10.1111/acel.14130

PMCID:: PMC11166371

Abstract Article PDF–31M

Select item 107557982.

miR-125a-5p/miR-125b-5p contributes to pathological activation of angiotensin II-AT1R in mouse distal convoluted tubule cells by the suppression of Atrap

Keigo Hirota, Akio Yamashita, Eriko Abe, Takahiro Yamaji, Kengo Azushima, Shohei Tanaka, Shinya Taguchi, Shunichiro Tsukamoto, Hiromichi Wakui, Kouichi Tamura

J Biol Chem. 2023 Dec; 299(12): 105478. Published online 2023 Nov 21. doi: 10.1016/j.jbc.2023.105478

PMCID:: PMC10755798

Abstract Article PDF–1.4M

Select item 96540333.

Increased Arterial Responsiveness to Angiotensin II in Mice Conceived by Assisted Reproductive Technologies

Theo Arthur Meister, Rodrigo Soria, Afzal Dogar, Franz H. Messerli, Ariane Paoloni-Giacobino, Ludwig Stenz, Urs Scherrer, Claudio Sartori, Emrush Rexhaj

Int J Mol Sci. 2022 Nov; 23(21): 13357. Published online 2022 Nov 1. doi: 10.3390/ijms232113357

PMCID:: PMC9654033

Abstract Article PDF–984K

Select item 95767474.

Angiotensin II type-1 receptor-associated protein interacts with transferrin receptor-1 and promotes its internalization

Eriko Abe, Akio Yamashita, Keigo Hirota, Takahiro Yamaji, Kengo Azushima, Shingo Urate, Toru Suzuki, Shohei Tanaka, Shinya Taguchi, Shunichiro Tsukamoto, Tatsuki Uehara, Hiromichi Wakui, Kouichi Tamura, Hidehisa Takahashi

Sci Rep. 2022; 12: 17376. Published online 2022 Oct 17. doi: 10.1038/s41598-022-22343-5

Correction in:: Sci Rep. 2022; 12: 21322.

PMCID:: PMC9576747

Abstract Article PDF–2.8M

Select item 92458325.

Myogenic Vasoconstriction Requires Canonical G_q/11 Signaling of the Angiotensin II Type 1 Receptor

Yingqiu Cui, Mario Kassmann, Sophie Nickel, Chenglin Zhang, Natalia Alenina, Yoland Marie Anistan, Johanna Schleifenbaum, Michael Bader, Donald G. Welsh, Yu Huang, Maik Gollasch

J Am Heart Assoc. 2022 Feb 15; 11(4): e022070. Published online 2022 Feb 12. doi: 10.1161/JAHA.121.022070

PMCID:: PMC9245832

Abstract Article PDF–4.1M

Select item 92221116.

The Functional Interaction of EGFR with AT1R or TP in Primary Vascular Smooth Muscle Cells Triggers a Synergistic Regulation of Gene Expression

Virginie Dubourg, Barbara Schreier, Gerald Schwerdt, Sindy Rabe, Ralf A. Benndorf, Michael Gekle

Cells. 2022 Jun; 11(12): 1936. Published online 2022 Jun 16. doi: 10.3390/cells11121936

PMCID:: PMC9222111

Abstract Article PDF–3.7M

Select item 80301247.

Impaired angiotensin II type 1 receptor signaling contributes to sepsis-induced acute kidney injury

Daniel E. Leisman, Tiago D. Fernandes, Vanesa Bijol, Mabel N. Abraham, Jake R. Lehman, Matthew D. Taylor, Christine Capone, Omar Yaipan, Rinaldo Bellomo, Clifford S. Deutschman

Kidney Int. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Kidney Int. 2021 Jan; 99(1): 148–160. Published online 2020 Aug 31. doi: 10.1016/j.kint.2020.07.047

PMCID:: PMC8030124

Abstract Article PDF–1.4M

Select item 77660858.

Functional Complexes of Angiotensin-Converting Enzyme 2 and Renin-Angiotensin System Receptors: Expression in Adult but Not Fetal Lung Tissue

Rafael Franco, Alejandro Lillo, Rafael Rivas-Santisteban, Ana I. Rodríguez-Pérez, Irene Reyes-Resina, José L. Labandeira-García, Gemma Navarro

Int J Mol Sci. 2020 Dec; 21(24): 9602. Published online 2020 Dec 16. doi: 10.3390/ijms21249602

PMCID:: PMC7766085

Abstract Article PDF–7.2M

Select item 74539709.

Role of Angiotensin II type 1 (AT1) and type 2 (AT2) receptors in airway reactivity and inflammation in an allergic mouse model of asthma

Mehaben Patel, Mangesh Kurade, Sahith Rajalingam, Riya Bhavsar, S Jamal Mustafa, Dovenia S. Ponnoth

Immunopharmacol Immunotoxicol. Author manuscript; available in PMC 2020 Aug 28.

Published in final edited form as: Immunopharmacol Immunotoxicol. 2019 Jun; 41(3): 428–437. Published online 2019 May 7. doi: 10.1080/08923973.2019.1609026

PMCID:: PMC7453970

Abstract Article PDF–1.4M

Select item 713198010.

The pathophysiological role of angiotensin receptor-binding protein in hypertension and kidney diseases: Oshima Award Address 2019

Hiromichi Wakui

Clin Exp Nephrol. 2020; 24(4): 289–294. Published online 2020 Feb 29. doi: 10.1007/s10157-020-01861-4

PMCID:: PMC7131980

Abstract Article PDF–493K

Select item 692815511.

Angiotensin-Receptor-Associated Protein Modulates Ca²⁺ Signals in Photoreceptor and Mossy Fiber cells

Rene Barro-Soria, Alejandro Caicedo, Herbert Jägle, Laura Merkel, Na Zhao, Gabriel Knop, Kaspar Gierke, Andrea Dannullis, Hayo Castrop, Johann Helmut Brandstätter, Frank Kirchhoff, Andreas Feigenspan, Olaf Strauß

Sci Rep. 2019; 9: 19622. Published online 2019 Dec 23. doi: 10.1038/s41598-019-55380-8

PMCID:: PMC6928155

Abstract Article PDF–6.0M

Select item 650720512.

Effects of ATRAP in Renal Proximal Tubules on Angiotensin‐Dependent Hypertension

Sho Kinguchi, Hiromichi Wakui, Kengo Azushima, Kotaro Haruhara, Tomoyuki Koguchi, Kohji Ohki, Kazushi Uneda, Miyuki Matsuda, Sona Haku, Takahiro Yamaji, Takayuki Yamada, Ryu Kobayashi, Shintaro Minegishi, Tomoaki Ishigami, Akio Yamashita, Tetsuya Fujikawa, Kouichi Tamura

J Am Heart Assoc. 2019 Apr 16; 8(8): e012395. Published online 2019 Apr 12. doi: 10.1161/JAHA.119.012395

PMCID:: PMC6507205

Abstract Article PDF–1.1M

Select item 640287713.

Acute AT₁R blockade prevents isoproterenol-induced injury in mdx hearts

Tatyana A. Meyers, Jackie A. Heitzman, Aimee Krebsbach, Lauren M. Aufdembrink, Robert Hughes, Alessandro Bartolomucci, DeWayne Townsend

J Mol Cell Cardiol. Author manuscript; available in PMC 2020 Mar 1.

Published in final edited form as: J Mol Cell Cardiol. 2019 Mar; 128: 51–61. Published online 2019 Jan 19. doi: 10.1016/j.yjmcc.2019.01.013

PMCID:: PMC6402877

Abstract Article PDF–1.4M

Select item 640031914.

Reversal of Aortic Enlargement Due to Increased Biomechanical Forces Requires AT1R Inhibition in Conjunction with AT2R Activation

Zhen Zhou, Andrew M. Peters, Shanzhi Wang, Alexandra Janda, Jiyuan Chen, Ping Zhou, Erin Arthur, Callie S. Kwartler, Dianna M. Milewicz

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2020 Mar 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2019 Mar; 39(3): 459–466. doi: 10.1161/ATVBAHA.118.312158

PMCID:: PMC6400319

Abstract Article PDF–847K

Select item 558645315.

Angiotensin II Type 1 Receptor‐Associated Protein Regulates Kidney Aging and Lifespan Independent of Angiotensin

Kazushi Uneda, Hiromichi Wakui, Akinobu Maeda, Kengo Azushima, Ryu Kobayashi, Sona Haku, Kohji Ohki, Kotaro Haruhara, Sho Kinguchi, Miyuki Matsuda, Masato Ohsawa, Shintaro Minegishi, Tomoaki Ishigami, Yoshiyuki Toya, Yoshitoshi Atobe, Akio Yamashita, Satoshi Umemura, Kouichi Tamura

J Am Heart Assoc. 2017 Aug; 6(8): e006120. Published online 2017 Jul 27. doi: 10.1161/JAHA.117.006120

PMCID:: PMC5586453

Abstract Article PDF–1.3M

Select item 552400016.

Adipocyte‐Specific Enhancement of Angiotensin II Type 1 Receptor‐Associated Protein Ameliorates Diet‐Induced Visceral Obesity and Insulin Resistance

Kengo Azushima, Kohji Ohki, Hiromichi Wakui, Kazushi Uneda, Sona Haku, Ryu Kobayashi, Kotaro Haruhara, Sho Kinguchi, Miyuki Matsuda, Akinobu Maeda, Yoshiyuki Toya, Akio Yamashita, Satoshi Umemura, Kouichi Tamura

J Am Heart Assoc. 2017 Mar; 6(3): e004488. Published online 2017 Mar 6. doi: 10.1161/JAHA.116.004488

PMCID:: PMC5524000

Abstract Article PDF–1.6M

Select item 537268617.

ATRAP Expression in Brown Adipose Tissue Does Not Influence the Development of Diet-Induced Metabolic Disorders in Mice

Kohji Ohki, Hiromichi Wakui, Kengo Azushima, Kazushi Uneda, Sona Haku, Ryu Kobayashi, Kotaro Haruhara, Sho Kinguchi, Miyuki Matsuda, Masato Ohsawa, Akinobu Maeda, Shintaro Minegishi, Tomoaki Ishigami, Yoshiyuki Toya, Akio Yamashita, Satoshi Umemura, Kouichi Tamura

Int J Mol Sci. 2017 Mar; 18(3): 676. Published online 2017 Mar 21. doi: 10.3390/ijms18030676

PMCID:: PMC5372686

Abstract Article PDF–14M

Select item 473141318.

Neurorestoration after traumatic brain injury through angiotensin II receptor blockage

Sonia Villapol, María G. Balarezo, Kwame Affram, Juan M. Saavedra, Aviva J. Symes

Brain. 2015 Nov; 138(11): 3299–3315. Published online 2015 Jun 26. doi: 10.1093/brain/awv172

PMCID:: PMC4731413

Abstract Article PDF–1.9M

Select item 447956519.

Erythropoiesis and Blood Pressure Are Regulated via AT1 Receptor by Distinctive Pathways

Hideki Kato, Junji Ishida, Taiji Matsusaka, Tomohiro Ishimaru, Keiji Tanimoto, Fumihiro Sugiyama, Ken-ichi Yagami, Masaomi Nangaku, Akiyoshi Fukamizu

PLoS One. 2015; 10(6): e0129484. Published online 2015 Jun 24. doi: 10.1371/journal.pone.0129484

PMCID:: PMC4479565

Abstract Article PDF–3.3M

Select item 439243920.

Renal Tubule Angiotensin II Type 1 Receptor–Associated Protein Promotes Natriuresis and Inhibits Salt‐Sensitive Blood Pressure Elevation

Hiromichi Wakui, Kazushi Uneda, Kouichi Tamura, Masato Ohsawa, Kengo Azushima, Ryu Kobayashi, Kohji Ohki, Toru Dejima, Tomohiko Kanaoka, Yuko Tsurumi‐Ikeya, Miyuki Matsuda, Kotaro Haruhara, Akira Nishiyama, Machiko Yabana, Tetsuya Fujikawa, Akio Yamashita, Satoshi Umemura

J Am Heart Assoc. 2015 Mar; 4(3): e001594. Published online 2015 Mar 19. doi: 10.1161/JAHA.114.001594