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Select item 103381211.

Effect of moderate prenatal ethanol exposure on the differential expression of two histamine H3 receptor isoforms in different brain regions of adult rat offspring

Suzy Davies, Kiana S. Lujan, Ella J. Rappaport, Carlos F. Valenzuela, Daniel D. Savage

Front Neurosci. 2023; 17: 1192096. Published online 2023 Jun 28. doi: 10.3389/fnins.2023.1192096

PMCID:: PMC10338121

Abstract Article PDF–2.4M

Select item 101399992.

The histamine H3 receptor modulates dopamine D2 receptor–dependent signaling pathways and mouse behaviors

Jian Xu, Christopher Pittenger

J Biol Chem. 2023 Apr; 299(4): 104583. Published online 2023 Mar 4. doi: 10.1016/j.jbc.2023.104583

PMCID:: PMC10139999

Abstract Article PDF–6.9M

Select item 70129463.

The histidine decarboxylase model of tic pathophysiology: a new focus on the histamine H₃ receptor

Christopher Pittenger

Br J Pharmacol. 2020 Feb; 177(3): 570–579. Published online 2019 Mar 27. doi: 10.1111/bph.14606

PMCID:: PMC7012946

Abstract Article PDF–1.0M

Select item 69234244.

Helix 8 is the essential structural motif of mechanosensitive GPCRs

Serap Erdogmus, Ursula Storch, Laura Danner, Jasmin Becker, Michaela Winter, Nicole Ziegler, Angela Wirth, Stefan Offermanns, Carsten Hoffmann, Thomas Gudermann, Michael Mederos y Schnitzler

Nat Commun. 2019; 10: 5784. Published online 2019 Dec 19. doi: 10.1038/s41467-019-13722-0

PMCID:: PMC6923424

Abstract Article PDF–1.4M

Select item 62043185.

Striatal signaling regulated by the H3R histamine receptor in a mouse model of tic pathophysiology

Maximiliano Rapanelli, Luciana Frick, Kantiya Jindachomthong, Jian Xu, Hiroshi Ohtsu, Angus Nairn, Christopher Pittenger

Neuroscience. Author manuscript; available in PMC 2019 Nov 10.

Published in final edited form as: Neuroscience. 2018 Nov 10; 392: 172–179. Published online 2018 Sep 29. doi: 10.1016/j.neuroscience.2018.09.035

PMCID:: PMC6204318

Abstract Article PDF–1.3M

Select item 55457436.

Histamine H3R receptor activation in the dorsal striatum triggers stereotypies in a mouse model of tic disorders

M Rapanelli, L Frick, V Pogorelov, H Ohtsu, H Bito, C Pittenger

Transl Psychiatry. 2017 Jan; 7(1): e1013. Published online 2017 Jan 24. doi: 10.1038/tp.2016.290

PMCID:: PMC5545743

Abstract Article PDF–1.5M

Select item 50765147.

The Histamine H3 Receptor Differentially Modulates Mitogen-activated Protein Kinase (MAPK) and Akt Signaling in Striatonigral and Striatopallidal Neurons

Maximiliano Rapanelli, Luciana R. Frick, Kyla D. Horn, Rivka C. Schwarcz, Vladimir Pogorelov, Angus C. Nairn, Christopher Pittenger

J Biol Chem. 2016 Sep 30; 291(40): 21042–21052. Published online 2016 Aug 10. doi: 10.1074/jbc.M116.731406

PMCID:: PMC5076514

Abstract Article PDF–2.3M

Select item 46755408.

On the Role of Histamine Receptors in the Regulation of Circadian Rhythms

Stanislav V. Rozov, Tarja Porkka-Heiskanen, Pertti Panula

PLoS One. 2015; 10(12): e0144694. Published online 2015 Dec 10. doi: 10.1371/journal.pone.0144694

PMCID:: PMC4675540

Abstract Article PDF–3.4M

Select item 43195599.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 394807710.

Histamine H3 receptors aggravate cerebral ischaemic injury by histamine-independent mechanisms

Haijing Yan, Xiangnan Zhang, Weiwei Hu, Jing Ma, Weiwei Hou, Xingzhou Zhang, Xiaofen Wang, Jieqiong Gao, Yao Shen, Jianxin Lv, Hiroshi Ohtsu, Feng Han, Guanghui Wang, Zhong Chen

Nat Commun. 2014 Feb 25; 5: 3334. Published online 2014 Feb 25. doi: 10.1038/ncomms4334

PMCID:: PMC3948077

Abstract Article PDF–2.5M

Select item 394257311.

Cocaine Disrupts Histamine H₃ Receptor Modulation of Dopamine D₁ Receptor Signaling: σ₁-D₁-H₃ Receptor Complexes as Key Targets for Reducing Cocaine's Effects

Estefanía Moreno, David Moreno-Delgado, Gemma Navarro, Hanne M. Hoffmann, Silvia Fuentes, Santi Rosell-Vilar, Paola Gasperini, Mar Rodríguez-Ruiz, Mireia Medrano, Josefa Mallol, Antoni Cortés, Vicent Casadó, Carme Lluís, Sergi Ferré, Jordi Ortiz, Enric Canela, Peter J. McCormick

J Neurosci. 2014 Mar 5; 34(10): 3545–3558. doi: 10.1523/JNEUROSCI.4147-13.2014

PMCID:: PMC3942573

Abstract Article PDF–3.3M

Select item 387470512.

The expression and function of histamine H₃ receptors in pancreatic beta cells

T Nakamura, T Yoshikawa, N Noguchi, A Sugawara, A Kasajima, H Sasano, K Yanai

Br J Pharmacol. 2014 Jan; 171(1): 171–185. Published online 2013 Dec 10. doi: 10.1111/bph.12429

PMCID:: PMC3874705

Abstract Article PDF–2.0M

Select item 374723213.

Systemic Lack of Canonical Histamine Receptor Signaling Results in Increased Resistance to Autoimmune Encephalomyelitis

Naresha Saligrama, Laure K Case, Roxana Del Rio, Rajkumar Noubade, Cory Teuscher

J Immunol. Author manuscript; available in PMC 2014 Jul 15.

Published in final edited form as: J Immunol. 2013 Jul 15; 191(2): 614–622. Published online 2013 Jun 14. doi: 10.4049/jimmunol.1203137

PMCID:: PMC3747232

Abstract Article PDF–1.5M

Select item 371878814.

Histamine H₃ Receptor Integrates Peripheral Inflammatory Signals in the Neurogenic Control of Immune Responses and Autoimmune Disease Susceptibility

Dimitry N. Krementsov, Emma H. Wall, Rebecca A. Martin, Meenakumari Subramanian, Rajkumar Noubade, Roxana Del Rio, Gary M. Mawe, Jeffrey P. Bond, Matthew E. Poynter, Elizabeth P. Blankenhorn, Cory Teuscher

PLoS One. 2013; 8(7): e62743. Published online 2013 Jul 22. doi: 10.1371/journal.pone.0062743

PMCID:: PMC3718788

Abstract Article PDF–1.6M

Select item 362939115.

Enhanced Histaminergic Neurotransmission and Sleep-Wake Alterations, a Study in Histamine H3-Receptor Knock-Out Mice

Elise Gondard, Christelle Anaclet, Hidéo Akaoka, Rui-Xian Guo, Mei Zhang, Colette Buda, Patricia Franco, Hidehito Kotani, Jian-Sheng Lin

Neuropsychopharmacology. 2013 May; 38(6): 1015–1031. Prepublished online 2013 Jan 2. Published online 2013 Feb 13. doi: 10.1038/npp.2012.266

PMCID:: PMC3629391

Abstract Article PDF–1.2M

Select item 357241016.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163