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Items: 1 to 20 of 26

1.
AMPK phosphorylation of FNIP1 (S220) controls mitochondrial function and muscle fuel utilization during exercise
Liwei Xiao, Yujing Yin, Zongchao Sun, Jing Liu, Yuhuan Jia, Likun Yang, Yan Mao, Shujun Peng, Zhifu Xie, Lei Fang, Jingya Li, Xiaoduo Xie, Zhenji Gan
Sci Adv. 2024 Feb 9; 10(6): eadj2752. Published online 2024 Feb 7. doi: 10.1126/sciadv.adj2752
PMCID:
PMC10849678
AbstractArticlePDF–8.0M
2.
FNIP1 abrogation promotes functional revascularization of ischemic skeletal muscle by driving macrophage recruitment
Zongchao Sun, Likun Yang, Abdukahar Kiram, Jing Yang, Zhuangzhuang Yang, Liwei Xiao, Yujing Yin, Jing Liu, Yan Mao, Danxia Zhou, Hao Yu, Zheng Zhou, Dengqiu Xu, Yuhuan Jia, Chenyun Ding, Qiqi Guo, Hongwei Wang, Yan Li, Li Wang, Tingting Fu, Shijun Hu, Zhenji Gan
Nat Commun. 2023; 14: 7136. Published online 2023 Nov 6. doi: 10.1038/s41467-023-42690-9
PMCID:
PMC10628247
AbstractArticlePDF–5.8M
3.
Functional TFEB activation characterizes multiple models of renal cystic disease and loss of polycystin-1
Jonathan M. Shillingford, James A. Shayman
Am J Physiol Renal Physiol. 2023 Apr 1; 324(4): F404–F422. Published online 2023 Feb 16. doi: 10.1152/ajprenal.00237.2022
PMCID:
PMC10069964
AbstractArticle
4.
FNIP1 regulates adipocyte browning and systemic glucose homeostasis in mice by shaping intracellular calcium dynamics
Yujing Yin, Dengqiu Xu, Yan Mao, Liwei Xiao, Zongchao Sun, Jing Liu, Danxia Zhou, Zhisheng Xu, Lin Liu, Tingting Fu, Chenyun Ding, Qiqi Guo, Wanping Sun, Zheng Zhou, Likun Yang, Yuhuan Jia, Xinyi Chen, Zhenji Gan
J Exp Med. 2022 May 2; 219(5): e20212491. Published online 2022 Apr 12. doi: 10.1084/jem.20212491
PMCID:
PMC9008465
AbstractArticlePDF–7.2M
5.
Structural basis and regulation of the reductive stress response
Andrew G. Manford, Elijah L. Mena, Karen Y. Shih, Christine L. Gee, Rachael McMinimy, Brenda Martínez-González, Rumi Sherriff, Brandon Lew, Madeline Zoltek, Fernando Rodríguez-Pérez, Makda Woldesenbet, John Kuriyan, Michael Rape
Cell. Author manuscript; available in PMC 2022 Oct 14.
Published in final edited form as: Cell. 2021 Oct 14; 184(21): 5375–5390.e16. Published online 2021 Sep 24. doi: 10.1016/j.cell.2021.09.002
PMCID:
PMC8810291
AbstractArticlePDF–1.5M
6.
AMPK-dependent and -independent coordination of mitochondrial function and muscle fiber type by FNIP1
Liwei Xiao, Jing Liu, Zongchao Sun, Yujing Yin, Yan Mao, Dengqiu Xu, Lin Liu, Zhisheng Xu, Qiqi Guo, Chenyun Ding, Wanping Sun, Likun Yang, Zheng Zhou, Danxia Zhou, Tingting Fu, Wenjing Zhou, Yuangang Zhu, Xiao-Wei Chen, John Zhong Li, Shuai Chen, Xiaoduo Xie, Zhenji Gan
PLoS Genet. 2021 Mar; 17(3): e1009488. Published online 2021 Mar 29. doi: 10.1371/journal.pgen.1009488
PMCID:
PMC8031738
AbstractArticlePDF–6.6M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
Folliculin Interacting Protein-1 Maintains Metabolic Homeostasis During B Cell Development by Modulating AMPK, mTORC1, and TFE3
Julita A. Ramίrez, Terri Iwata, Heon Park, Mark Tsang, Janella Kang, Katy Cui, Winnie Kwong, Richard G. James, Masaya Baba, Laura S. Schmidt, Brian M. Iritani
J Immunol. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: J Immunol. 2019 Dec 1; 203(11): 2899–2908. Published online 2019 Nov 1. doi: 10.4049/jimmunol.1900395
PMCID:
PMC6864314
AbstractArticlePDF–1.6M
9.
Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation
Ryan Centini, Mark Tsang, Terri Iwata, Heon Park, Jeffrey Delrow, Daciana Margineantu, Brandon M. Iritani, Haiwei Gu, H. Denny Liggitt, Janella Kang, Lim Kang, David M. Hockenbery, Daniel Raftery, Brian M. Iritani
PLoS One. 2018; 13(6): e0197973. Published online 2018 Jun 13. doi: 10.1371/journal.pone.0197973
PMCID:
PMC5999084
AbstractArticlePDF–12M
10.
Mammalian γ2 AMPK regulates intrinsic heart rate
Arash Yavari, Mohamed Bellahcene, Annalisa Bucchi, Syevda Sirenko, Katalin Pinter, Neil Herring, Julia J. Jung, Kirill V. Tarasov, Emily J. Sharpe, Markus Wolfien, Gabor Czibik, Violetta Steeples, Sahar Ghaffari, Chinh Nguyen, Alexander Stockenhuber, Joshua R. St. Clair, Christian Rimmbach, Yosuke Okamoto, Dongmei Yang, Mingyi Wang, Bruce D. Ziman, Jack M. Moen, Daniel R. Riordon, Christopher Ramirez, Manuel Paina, Joonho Lee, Jing Zhang, Ismayil Ahmet, Michael G. Matt, Yelena S. Tarasova, Dilair Baban, Natasha Sahgal, Helen Lockstone, Rathi Puliyadi, Joseph de Bono, Owen M. Siggs, John Gomes, Hannah Muskett, Mahon L. Maguire, Youlia Beglov, Matthew Kelly, Pedro P. N. dos Santos, Nicola J. Bright, Angela Woods, Katja Gehmlich, Henrik Isackson, Gillian Douglas, David J. P. Ferguson, Jürgen E. Schneider, Andrew Tinker, Olaf Wolkenhauer, Keith M. Channon, Richard J. Cornall, Eduardo B. Sternick, David J. Paterson, Charles S. Redwood, David Carling, Catherine Proenza, Robert David, Mirko Baruscotti, Dario DiFrancesco, Edward G. Lakatta, Hugh Watkins, Houman Ashrafian
Nat Commun. 2017; 8: 1258. Published online 2017 Nov 2. doi: 10.1038/s41467-017-01342-5
PMCID:
PMC5668267
AbstractArticlePDF–2.8M
11.
Coupling of mitochondrial function and skeletal muscle fiber type by a miR‐499/Fnip1/AMPK circuit
Jing Liu, Xijun Liang, Danxia Zhou, Ling Lai, Liwei Xiao, Lin Liu, Tingting Fu, Yan Kong, Qian Zhou, Rick B Vega, Min‐Sheng Zhu, Daniel P Kelly, Xiang Gao, Zhenji Gan
EMBO Mol Med. 2016 Oct; 8(10): 1212–1228. Published online 2016 Aug 9. doi: 10.15252/emmm.201606372
PMCID:
PMC5048369
AbstractArticlePDF–2.9M
12.
Mutation of Fnip1 is associated with B-cell deficiency, cardiomyopathy, and elevated AMPK activity
Owen M. Siggs, Alexander Stockenhuber, Mukta Deobagkar-Lele, Katherine R. Bull, Tanya L. Crockford, Bethany L. Kingston, Greg Crawford, Consuelo Anzilotti, Violetta Steeples, Sahar Ghaffari, Gabor Czibik, Mohamed Bellahcene, Hugh Watkins, Houman Ashrafian, Benjamin Davies, Angela Woods, David Carling, Arash Yavari, Bruce Beutler, Richard J. Cornall
Proc Natl Acad Sci U S A. 2016 Jun 28; 113(26): E3706–E3715. Published online 2016 Jun 14. doi: 10.1073/pnas.1607592113
PMCID:
PMC4932993
AbstractArticlePDF–2.0M
13.
Folliculin-interacting proteins Fnip1 and Fnip2 play critical roles in kidney tumor suppression in cooperation with Flcn
Hisashi Hasumi, Masaya Baba, Yukiko Hasumi, Martin Lang, Ying Huang, HyoungBin F. Oh, Masayuki Matsuo, Maria J. Merino, Masahiro Yao, Yusuke Ito, Mitsuko Furuya, Yasuhiro Iribe, Tatsuhiko Kodama, Eileen Southon, Lino Tessarollo, Kunio Nagashima, Diana C. Haines, W. Marston Linehan, Laura S. Schmidt
Proc Natl Acad Sci U S A. 2015 Mar 31; 112(13): E1624–E1631. Published online 2015 Mar 16. doi: 10.1073/pnas.1419502112
PMCID:
PMC4386336
AbstractArticlePDF–1.9M
14.
Fnip1 regulates skeletal muscle fiber type specification, fatigue resistance, and susceptibility to muscular dystrophy
Nicholas L. Reyes, Glen B. Banks, Mark Tsang, Daciana Margineantu, Haiwei Gu, Danijel Djukovic, Jacky Chan, Michelle Torres, H. Denny Liggitt, Dinesh K. Hirenallur-S, David M. Hockenbery, Daniel Raftery, Brian M. Iritani
Proc Natl Acad Sci U S A. 2015 Jan 13; 112(2): 424–429. Published online 2014 Dec 29. doi: 10.1073/pnas.1413021112
PMCID:
PMC4299192
AbstractArticlePDF–1.2M
15.
Metabolic regulator Fnip1 is crucial for iNKT lymphocyte development
Heon Park, Mark Tsang, Brian M. Iritani, Michael J. Bevan
Proc Natl Acad Sci U S A. 2014 May 13; 111(19): 7066–7071. Published online 2014 Apr 30. doi: 10.1073/pnas.1406473111
PMCID:
PMC4024901
AbstractArticlePDF–1.1M
16.
Recruitment of folliculin to lysosomes supports the amino acid–dependent activation of Rag GTPases
Constance S. Petit, Agnes Roczniak-Ferguson, Shawn M. Ferguson
J Cell Biol. 2013 Sep 30; 202(7): 1107–1122. doi: 10.1083/jcb.201307084
PMCID:
PMC3787382
AbstractArticlePDF–4.1M
17.
Exit from Pluripotency Is Gated by Intracellular Redistribution of the bHLH Transcription Factor Tfe3
Joerg Betschinger, Jennifer Nichols, Sabine Dietmann, Philip D. Corrin, Patrick J. Paddison, Austin Smith
Cell. 2013 Apr 11; 153(2): 335–347. doi: 10.1016/j.cell.2013.03.012
PMCID:
PMC3661979
AbstractArticlePDF–2.8M
18.
The folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dubé syndrome is required for murine B-cell development
Masaya Baba, Jonathan R. Keller, Hong-Wei Sun, Wolfgang Resch, Stefan Kuchen, Hyung Chan Suh, Hisashi Hasumi, Yukiko Hasumi, Kyong-Rim Kieffer-Kwon, Carme Gallego Gonzalez, Robert M. Hughes, Mara E. Klein, Hyoungbin F. Oh, Paul Bible, Eileen Southon, Lino Tessarollo, Laura S. Schmidt, W. Marston Linehan, Rafael Casellas
Blood. 2012 Aug 9; 120(6): 1254–1261. Prepublished online 2012 Jun 18. doi: 10.1182/blood-2012-02-410407
PMCID:
PMC3418720
AbstractArticle
19.
Disruption of Fnip1 reveals a metabolic checkpoint controlling B lymphocyte development
Heon Park, Karen Staehling, Mark Tsang, Mark W. Appleby, Mary E. Brunkow, Daciana Margineantu, David M. Hockenbery, Tania Habib, H. Denny Liggitt, George Carlson, Brian M. Iritani
Immunity. Author manuscript; available in PMC 2013 May 25.
Published in final edited form as: Immunity. 2012 May 25; 36(5): 769–781. Published online 2012 May 17. doi: 10.1016/j.immuni.2012.02.019
PMCID:
PMC3361584
AbstractArticlePDF–4.5M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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