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Items: 1 to 20 of 66

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Btbd11 supports cell-type-specific synaptic function
Alexei M. Bygrave, Ayesha Sengupta, Ella P. Jackert, Mehroz Ahmed, Beloved Adenuga, Erik Nelson, Hana L. Goldschmidt, Richard C. Johnson, Haining Zhong, Felix L. Yeh, Morgan Sheng, Richard L. Huganir
Cell Rep. Author manuscript; available in PMC 2023 Oct 23.
Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112591. Published online 2023 May 31. doi: 10.1016/j.celrep.2023.112591
PMCID:
PMC10592477
AbstractArticlePDF–3.6M
3.
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome
Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh
Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5
PMCID:
PMC10208958
AbstractArticlePDF–7.0M
4.
Selective behavioural impairments in mice heterozygous for the cross disorder psychiatric risk gene DLG2
Rachel Pass, Niels Haan, Trevor Humby, Lawrence S. Wilkinson, Jeremy Hall, Kerrie L. Thomas
Genes Brain Behav. 2022 Apr; 21(4): e12799. Published online 2022 Feb 3. doi: 10.1111/gbb.12799
PMCID:
PMC9393930
AbstractArticlePDF–4.2M
5.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
6.
MAGUKs are essential, but redundant, in long-term potentiation
Xiumin Chen, Yuko Fukata, Masaki Fukata, Roger A. Nicoll
Proc Natl Acad Sci U S A. 2021 Jul 13; 118(28): e2107585118. Published online 2021 Jul 9. doi: 10.1073/pnas.2107585118
PMCID:
PMC8285982
AbstractArticlePDF–1.2M
7.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
8.
Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant
Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely
Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089
PMCID:
PMC7295033
AbstractArticlePDF–2.7M
9.
A DLG2 deficiency in mice leads to reduced sociability and increased repetitive behavior accompanied by aberrant synaptic transmission in the dorsal striatum
Taesun Yoo, Sun-Gyun Kim, Soo Hyun Yang, Hyun Kim, Eunjoon Kim, Soo Young Kim
Mol Autism. 2020; 11: 19. Published online 2020 Mar 12. doi: 10.1186/s13229-020-00324-7
PMCID:
PMC7069029
AbstractArticlePDF–2.1M
10.
PSD-93 Knock-Out Mice Reveal That Neuronal MAGUKs Are Not Required for Development or Function of Parallel Fiber Synapses in Cerebellum
Aaron W. McGee, J. Rick Topinka, Kouichi Hashimoto, Ronald S. Petralia, Sho Kakizawa, Frederick Kauer, Andrea Aguilera-Moreno, Robert J. Wenthold, Masanobu Kano, David S. Bredt
J Neurosci. 2001 May 1; 21(9): 3085–3091. doi: 10.1523/JNEUROSCI.21-09-03085.2001
Correction in:
J Neurosci. 2003 May 1; 23(9): 0.
PMCID:
PMC6762564
AbstractArticlePDF–540K
11.
Cross-species genomics identifies DLG2 as a tumor suppressor in osteosarcoma
Yang W. Shao, Geoffrey A. Wood, Jinchang Lu, Qing-Lian Tang, Jonathan Liu, Sam Molyneux, Yan Chen, Hui Fang, Hibret Adissu, Trevor McKee, Paul Waterhouse, Rama Khokha
Oncogene. 2019; 38(2): 291–298. Published online 2018 Aug 9. doi: 10.1038/s41388-018-0444-4
PMCID:
PMC6756098
AbstractArticlePDF–3.0M
12.
Impaired NMDA Receptor-Mediated Postsynaptic Function and Blunted NMDA Receptor-Dependent Persistent Pain in Mice Lacking Postsynaptic Density-93 Protein
Yuan-Xiang Tao, Gavin Rumbaugh, Guo-Du Wang, Ronald S. Petralia, Chengshui Zhao, Frederick W. Kauer, Feng Tao, Min Zhuo, Robert J. Wenthold, Srinivasa N. Raja, Richard L. Huganir, David S. Bredt, Roger A. Johns
J Neurosci. 2003 Jul 30; 23(17): 6703–6712. doi: 10.1523/JNEUROSCI.23-17-06703.2003
PMCID:
PMC6740737
AbstractArticlePDF–453K
13.
PSD93 Regulates Synaptic Stability at Neuronal Cholinergic Synapses
Michael J. Parker, Shengli Zhao, David S. Bredt, Joshua R. Sanes, Guoping Feng
J Neurosci. 2004 Jan 14; 24(2): 378–388. doi: 10.1523/JNEUROSCI.3865-03.2004
PMCID:
PMC6729987
AbstractArticlePDF–588K
14.
Defects in Synaptic Plasticity, Reduced NMDA-Receptor Transport, and Instability of Postsynaptic Density Proteins in Mice Lacking Microtubule-Associated Protein 1A
Yosuke Takei, Yayoi S. Kikkawa, Nafiseh Atapour, Takao K. Hensch, Nobutaka Hirokawa
J Neurosci. 2015 Nov 25; 35(47): 15539–15554. doi: 10.1523/JNEUROSCI.2671-15.2015
PMCID:
PMC6705472
AbstractArticlePDF–4.7M
15.
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules
Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer
J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252
PMCID:
PMC6602300
AbstractArticle
16.
Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner
Paul R. Evans, Kyle J. Gerber, Eric B. Dammer, Duc M. Duong, Devrishi Goswami, Daniel J. Lustberg, Juan Zou, Jenny J. Yang, Serena M. Dudek, Patrick R. Griffin, Nicholas T. Seyfried, John R. Hepler
J Proteome Res. Author manuscript; available in PMC 2019 Jun 7.
Published in final edited form as: J Proteome Res. 2018 Apr 6; 17(4): 1700–1711. Published online 2018 Mar 20. doi: 10.1021/acs.jproteome.8b00027
PMCID:
PMC6554723
AbstractArticlePDF–2.0M
17.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
18.
PIP3-Phldb2 is crucial for LTP regulating synaptic NMDA and AMPA receptor density and PSD95 turnover
Min-Jue Xie, Yasuyuki Ishikawa, Hideshi Yagi, Tokuichi Iguchi, Yuichiro Oka, Kazuki Kuroda, Keiko Iwata, Hiroshi Kiyonari, Shinji Matsuda, Hideo Matsuzaki, Michisuke Yuzaki, Yugo Fukazawa, Makoto Sato
Sci Rep. 2019; 9: 4305. Published online 2019 Mar 13. doi: 10.1038/s41598-019-40838-6
PMCID:
PMC6416313
AbstractArticlePDF–7.6M
19.
RPS23RG1 is Required for Synaptic Integrity and Rescues Alzheimer’s Associated Cognitive Deficits
Dongdong Zhao, Jian Meng, Yingjun Zhao, Yuanhui Huo, Yan Liu, Naizhen Zheng, Muxian Zhang, Yue Gao, Zhicai Chen, Hao Sun, Xiangyu Wang, Chuya Jing, Tongmei Zhang, Xian Zhang, Hong Luo, Xin Wang, Jie Zhang, Fa-rong Liu, Yanfang Li, Guojun Bu, Lei Wen, Timothy Y. Huang, Huaxi Xu, Yun-wu Zhang
Biol Psychiatry. Author manuscript; available in PMC 2020 Aug 1.
Published in final edited form as: Biol Psychiatry. 2019 Aug 1; 86(3): 171–184. Published online 2018 Aug 25. doi: 10.1016/j.biopsych.2018.08.009
PMCID:
PMC6389446
AbstractArticlePDF–3.3M
20.
Identification of a novel Dlg2 isoform differentially expressed in IFNβ-producing plasmacytoid dendritic cells
Shafaqat Ali, Alexander Hoven, Regine J. Dress, Heiner Schaal, Judith Alferink, Stefanie Scheu
BMC Genomics. 2018; 19: 194. Published online 2018 Mar 12. doi: 10.1186/s12864-018-4573-5
PMCID:
PMC6389146
AbstractArticlePDF–1.2M

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