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Select item 111094831.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 107452002.

FBXO3 stabilizes USP4 and Twist1 to promote PI3K-mediated breast cancer metastasis

Jing Xu, Rongtian Guo, Nasi Wen, Luping Li, Yong Yi, Jingzhen Chen, Zongyu He, Jian Yang, Zhi-Xiong Jim Xiao, Mengmeng Niu

PLoS Biol. 2023 Dec; 21(12): e3002446. Published online 2023 Dec 22. doi: 10.1371/journal.pbio.3002446

PMCID:: PMC10745200

Abstract Article PDF–3.2M

Select item 106382973.

USP4 promotes the proliferation, migration, and invasion of esophageal squamous cell carcinoma by targeting TAK1

Hongdian Zhang, Youming Han, Wanyi Xiao, Yongyin Gao, Zhilin Sui, Peng Ren, Fanbiao Meng, Peng Tang, Zhentao Yu

Cell Death Dis. 2023 Nov; 14(11): 730. Published online 2023 Nov 10. doi: 10.1038/s41419-023-06259-0

PMCID:: PMC10638297

Abstract Article PDF–4.8M

Select item 104231054.

High USP4 mRNA is associated with an HPV-positive status in head and neck squamous cell carcinoma patients

Alexandra Scheiflinger, Sega Al-Gboore, Bernhard J. Jank, Faris Brkic, Lorenz Kadletz-Wanke, Lukas Kenner, Gregor Heiduschka, Julia Schnoell

J Cancer Res Clin Oncol. 2023; 149(12): 10675–10683. Published online 2023 Jun 12. doi: 10.1007/s00432-023-04872-2

PMCID:: PMC10423105

Abstract Article PDF–1.4M

Select item 102374225.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 92792856.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 92383607.

Transcriptome Analysis and Single-Cell Sequencing Analysis Constructed the Ubiquitination-Related Signature in Glioma and Identified USP4 as a Novel Biomarker

Qikai Tang, Zhengxin Chen, Jiaheng Xie, Chuangqi Mo, Jiacheng Lu, Qixiang Zhang, Zhangjie Wang, Wei Wu, Huibo Wang

Front Immunol. 2022; 13: 915709. Published online 2022 Jun 14. doi: 10.3389/fimmu.2022.915709

PMCID:: PMC9238360

Abstract Article PDF–18M

Select item 91813608.

The ubiquitin specific protease 4 (USP4) is a new player in the Wnt signalling pathway

Bin Zhao, Claudia Schlesiger, Maria G. Masucci, Kristina Lindsten

J Cell Mol Med. 2009 Aug; 13(8b): 1886–1895. Published online 2009 Nov 26. doi: 10.1111/j.1582-4934.2008.00682.x

PMCID:: PMC9181360

Abstract Article PDF–947K

Select item 90205179.

Structural and functional consequences of NEDD8 phosphorylation

Katrin Stuber, Tobias Schneider, Jill Werner, Michael Kovermann, Andreas Marx, Martin Scheffner

Nat Commun. 2021; 12: 5939. Published online 2021 Oct 12. doi: 10.1038/s41467-021-26189-9

PMCID:: PMC9020517

Abstract Article PDF–2.8M

Select item 878288110.

Deubiquitinating enzymes USP4 and USP17 finetune the trafficking of PDGFRβ and affect PDGF-BB-induced STAT3 signalling

Niki Sarri, Kehuan Wang, Maria Tsioumpekou, Casimiro Castillejo-López, Johan Lennartsson, Carl-Henrik Heldin, Natalia Papadopoulos

Cell Mol Life Sci. 2022 Feb; 79(2): 85. Published online 2022 Jan 21. doi: 10.1007/s00018-022-04128-1

PMCID:: PMC8782881

Abstract Article PDF–3.7M

Select item 855290711.

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo

Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396

PMCID:: PMC8552907

Abstract Article PDF–3.9M

Select item 848181812.

Intervention of Gastrodin in Type 2 Diabetes Mellitus and Its Mechanism

Yu Bai, Ke Mo, Guirong Wang, Wanling Chen, Wei Zhang, Yibo Guo, Zhirong Sun

Front Pharmacol. 2021; 12: 710722. Published online 2021 Sep 16. doi: 10.3389/fphar.2021.710722

PMCID:: PMC8481818

Abstract Article PDF–3.6M

Select item 846297413.

Photocaged Cell-Permeable Ubiquitin Probe for Temporal Profiling of Deubiquitinating Enzymes

Weijun Gui, Siqi Shen, Zhihao Zhuang

J Am Chem Soc. Author manuscript; available in PMC 2021 Nov 18.

Published in final edited form as: J Am Chem Soc. 2020 Nov 18; 142(46): 19493–19501. Published online 2020 Nov 3. doi: 10.1021/jacs.9b12426

PMCID:: PMC8462974

Abstract Article PDF–975K

Select item 838674014.

Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy

Waka Kojima, Koji Yamano, Hidetaka Kosako, Kenichiro Imai, Reika Kikuchi, Keiji Tanaka, Noriyuki Matsuda

Autophagy. 2021; 17(8): 2011–2036. Published online 2021 Jan 26. doi: 10.1080/15548627.2021.1874133

PMCID:: PMC8386740

Abstract Article PDF–13M

Select item 816503015.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 796055016.

USP11 mediates repair of DNA–protein cross-links by deubiquitinating SPRTN metalloprotease

Megan Perry, Meghan Biegert, Sai Sundeep Kollala, Halle Mallard, Grace Su, Manohar Kodavati, Natasha Kreiling, Alexander Holbrook, Gargi Ghosal

J Biol Chem. 2021 Jan-Jun; 296: 100396. Published online 2021 Feb 7. doi: 10.1016/j.jbc.2021.100396

PMCID:: PMC7960550

Abstract Article PDF–1.5M

Select item 792335017.

The male germline-specific protein MAPS is indispensable for pachynema progression and fertility

Miao Li, Jiahuan Zheng, Gaopeng Li, Zexiong Lin, Dongliang Li, Dongteng Liu, Haiwei Feng, Dandan Cao, Ernest H. Y. Ng, Raymond H. W. Li, Chunsheng Han, William S. B. Yeung, Louise T. Chow, Hengbin Wang, Kui Liu

Proc Natl Acad Sci U S A. 2021 Feb 23; 118(8): e2025421118. Published online 2021 Feb 18. doi: 10.1073/pnas.2025421118

PMCID:: PMC7923350

Abstract Article PDF–2.3M

Select item 791983618.

OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase

Hyo Jin Kim, Jongchan Kim

Int J Mol Sci. 2021 Feb; 22(4): 1936. Published online 2021 Feb 16. doi: 10.3390/ijms22041936

PMCID:: PMC7919836

Abstract Article PDF–5.0M

Select item 778828619.

USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells

Paul van den Berk, Cesare Lancini, Carlos Company, Michela Serresi, Maria Pilar Sanchez-Bailon, Danielle Hulsman, Colin Pritchard, Ji-Ying Song, Matthias Jürgen Schmitt, Ellen Tanger, Oliver Popp, Philipp Mertins, Ivo J. Huijbers, Heinz Jacobs, Maarten van Lohuizen, Gaetano Gargiulo, Elisabetta Citterio

Cell Rep. 2020 Dec 29; 33(13): 108533. Published online 2020 Dec 29. doi: 10.1016/j.celrep.2020.108533

PMCID:: PMC7788286

Abstract Article

Select item 735295820.

The Deubiquitinase USP4 Stabilizes Twist1 Protein to Promote Lung Cancer Cell Stemness

Fengtian Li, Qingyong Hu, Tao He, Jing Xu, Yong Yi, Siyi Xie, Liangping Ding, Mengyuan Fu, Rongtian Guo, Zhi-Xiong Jim Xiao, Mengmeng Niu

Cancers (Basel) 2020 Jun; 12(6): 1582. Published online 2020 Jun 15. doi: 10.3390/cancers12061582

PMCID:: PMC7352958

Abstract Article PDF–2.4M

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