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Select item 109391731.

Nuclear protein-1 is the common link for pathways activated by aging and obesity in chondrocytes: A potential therapeutic target for osteoarthritis

Li Tan, Alexandra R. Armstrong, Samuel Rosas, Chirayu M. Patel, Sabrina S. Vander Wiele, Jeffrey S. Willey, Cathy S. Carlson, Raghunatha R. Yammani

FASEB J. Author manuscript; available in PMC 2024 Mar 14.

Published in final edited form as: FASEB J. 2023 Sep; 37(9): e23133. doi: 10.1096/fj.202201700RR

PMCID:: PMC10939173

Abstract Article PDF–1.1M

Select item 105608952.

肾透明细胞癌中核蛋白1对阿昔替尼耐药的作用及机制

刘耘充, 吴宗龙, 葛力源, 杜坦, 吴雅倩, 宋一萌, 刘承, 马潞林

Beijing Da Xue Xue Bao Yi Xue Ban. 2023 Oct 18; 55(5): 781–792. Chinese. Published online 2023 Aug 25. doi: 10.19723/j.issn.1671-167X.2023.05.003

PMCID:: PMC10560895

Abstract Article PDF–9.5M

Select item 100671043.

NUPR1 imparts oncogenic potential in bladder cancer

Lifeng Zhang, Shenglin Gao, Xiaokai Shi, Yin Chen, Shuzhang Wei, Yuanyuan Mi, Li Zuo, Chunjian Qi

Cancer Med. 2023 Mar; 12(6): 7149–7163. Published online 2022 Dec 5. doi: 10.1002/cam4.5518

PMCID:: PMC10067104

Abstract Article PDF–30M

Select item 90354524.

NUPR1 promotes the proliferation and metastasis of oral squamous cell carcinoma cells by activating TFE3-dependent autophagy

Tengfei Fan, Xiaoning Wang, Sheng Zhang, Ping Deng, Yi Jiang, Yidan Liang, Sheng Jie, Qing Wang, Chuwen Li, Guocai Tian, Zhen Zhang, Zhenhu Ren, Bo Li, Yanrong Chen, Zhijing He, Yan Luo, Mingliang Chen, Hanjiang Wu, Zhengping Yu, Huifeng Pi, Zhou Zhou, Zhiyuan Zhang

Signal Transduct Target Ther. 2022; 7: 130. Published online 2022 Apr 25. doi: 10.1038/s41392-022-00939-7

Correction in:: Signal Transduct Target Ther. 2022; 7: 321.

PMCID:: PMC9035452

Abstract Article PDF–5.7M

Select item 89730695.

Histone methyltransferase Dot1L inhibits pancreatic cancer cell apoptosis by promoting NUPR1 expression

Lin Shan, Chen Hao, Zheng Jun, Cai Qinghe

J Int Med Res. 2022 Mar; 50(3): 03000605221088431. Published online 2022 Mar 29. doi: 10.1177/03000605221088431

PMCID:: PMC8973069

Abstract Article PDF–546K

Select item 85332026.

Design of Inhibitors of the Intrinsically Disordered Protein NUPR1: Balance between Drug Affinity and Target Function

Bruno Rizzuti, Wenjun Lan, Patricia Santofimia-Castaño, Zhengwei Zhou, Adrián Velázquez-Campoy, Olga Abián, Ling Peng, José L. Neira, Yi Xia, Juan L. Iovanna

Biomolecules. 2021 Oct; 11(10): 1453. Published online 2021 Oct 3. doi: 10.3390/biom11101453

PMCID:: PMC8533202

Abstract Article PDF–1.6M

Select item 83651767.

Induction of NUPR1 and AP-1 contributes to the carcinogenic potential of nickel

Anthony Murphy, Nirmal Roy, Hong Sun, Chunyuan Jin, Max Costa

Oncol Rep. 2021 Apr; 45(4): 41. Published online 2021 Feb 23. doi: 10.3892/or.2021.7992

PMCID:: PMC8365176

Abstract Article PDF–620K

Select item 82028468.

NUPR1 is a novel potential biomarker and confers resistance to sorafenib in clear cell renal cell carcinoma by increasing stemness and targeting the PTEN/AKT/mTOR pathway

Wei He, Fajuan Cheng, Bin Zheng, Jianwei Wang, Guiting Zhao, Zhongshun Yao, Tong Zhang

Aging (Albany NY) 2021 May 31; 13(10): 14015–14038. Published online 2021 May 24. doi: 10.18632/aging.203012

PMCID:: PMC8202846

Abstract Article PDF–3.6M

Select item 81650309.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 807008710.

Human Endogenous Retrovirus (HERV)-K env Gene Knockout Affects Tumorigenic Characteristics of nupr1 Gene in DLD-1 Colorectal Cancer Cells

Eun-Ji Ko, Mee-Sun Ock, Yung-Hyun Choi, Juan L. Iovanna, Seyoung Mun, Kyudong Han, Heui-Soo Kim, Hee-Jae Cha

Int J Mol Sci. 2021 Apr; 22(8): 3941. Published online 2021 Apr 11. doi: 10.3390/ijms22083941

PMCID:: PMC8070087

Abstract Article PDF–3.2M

Select item 800040811.

Inhibition of NUPR1–Karyopherin β1 Binding Increases Anticancer Drug Sensitivity

Chanhee Park, Jiwon Oh, Won Mo Lee, Hye Ran Koh, Uy Dong Sohn, Seung Wook Ham, Kyungsoo Oh

Int J Mol Sci. 2021 Mar; 22(6): 2794. Published online 2021 Mar 10. doi: 10.3390/ijms22062794

PMCID:: PMC8000408

Abstract Article PDF–21M

Select item 795829512.

Nuclear Protein 1 Imparts Oncogenic Potential and Chemotherapeutic Resistance in Cancer

Anthony Murphy, Max Costa

Cancer Lett. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Cancer Lett. 2020 Dec 1; 494: 132–141. Published online 2020 Aug 22. doi: 10.1016/j.canlet.2020.08.019

PMCID:: PMC7958295

Abstract Article PDF–870K

Select item 787650013.

microRNA‐637 promotes apoptosis and suppresses proliferation and autophagy in multiple myeloma cell lines via NUPR1

Xuanxin Chen, Anmao Li, Qian Zhan, Zizi Jing, Yiyu Chen, Jianbin Chen

FEBS Open Bio. 2021 Feb; 11(2): 519–528. Published online 2020 Dec 30. doi: 10.1002/2211-5463.13063

PMCID:: PMC7876500

Abstract Article PDF–2.8M

Select item 786227714.

Transcriptional coregualtor NUPR1 maintains tamoxifen resistance in breast cancer cells

Lingling Wang, Jiashen Sun, Yueyuan Yin, Yanan Sun, Jinyi Ma, Ruimin Zhou, Xinzhong Chang, Ding Li, Zhi Yao, Shanshan Tian, Kai Zhang, Zhe Liu, Zhenyi Ma

Cell Death Dis. 2021 Feb; 12(2): 149. Published online 2021 Feb 4. doi: 10.1038/s41419-021-03442-z

PMCID:: PMC7862277

Abstract Article PDF–2.9M

Select item 756598415.

A Phosphorylation-Induced Switch in the Nuclear Localization Sequence of the Intrinsically Disordered NUPR1 Hampers Binding to Importin

José L. Neira, Bruno Rizzuti, Ana Jiménez-Alesanco, Martina Palomino-Schätzlein, Olga Abián, Adrián Velázquez-Campoy, Juan L. Iovanna

Biomolecules. 2020 Sep; 10(9): 1313. Published online 2020 Sep 11. doi: 10.3390/biom10091313

PMCID:: PMC7565984

Abstract Article PDF–1.3M

Select item 753038016.

Trifluoperazine induces cellular apoptosis by inhibiting autophagy and targeting NUPR1 in multiple myeloma

Anmao Li, Xuanxin Chen, Zizi Jing, Jianbin Chen

FEBS Open Bio. 2020 Oct; 10(10): 2097–2106. Published online 2020 Aug 31. doi: 10.1002/2211-5463.12960

PMCID:: PMC7530380

Abstract Article PDF–2.1M

Select item 752655117.

ZZW-115–dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents

Wenjun Lan, Patricia Santofimia-Castaño, Mirna Swayden, Yi Xia, Zhengwei Zhou, Stephane Audebert, Luc Camoin, Can Huang, Ling Peng, Ana Jiménez-Alesanco, Adrián Velázquez-Campoy, Olga Abián, Gwen Lomberk, Raul Urrutia, Bruno Rizzuti, Vincent Geli, Philippe Soubeyran, José L. Neira, Juan Iovanna

JCI Insight. 2020 Sep 17; 5(18): e138117. Published online 2020 Sep 17. doi: 10.1172/jci.insight.138117

PMCID:: PMC7526551

Abstract Article PDF–9.1M

Select item 748367418.

Single Cell Transcriptomics Analysis Identifies Nuclear Protein 1 as a Regulator of Docetaxel Resistance in Prostate Cancer Cells

Patricia M. Schnepp, Greg Shelley, Jinlu Dai, Nicole Wakim, Hui Jiang, Atsushi Mizokami, Evan T. Keller

Mol Cancer Res. Author manuscript; available in PMC 2021 Mar 1.

Published in final edited form as: Mol Cancer Res. 2020 Sep; 18(9): 1290–1301. Published online 2020 Jun 8. doi: 10.1158/1541-7786.MCR-20-0051

PMCID:: PMC7483674

Abstract Article PDF–1.6M

Select item 668408419.

The cell fate regulator NUPR1 is induced by Mycobacterium leprae via type I interferon in human leprosy

Priscila R. Andrade, Manali Mehta, Jing Lu, Rosane M. B. Teles, Dennis Montoya, Phillip O. Scumpia, Euzenir Nunes Sarno, Maria Teresa Ochoa, Feiyang Ma, Matteo Pellegrini, Robert L. Modlin

PLoS Negl Trop Dis. 2019 Jul; 13(7): e0007589. Published online 2019 Jul 25. doi: 10.1371/journal.pntd.0007589

PMCID:: PMC6684084

Abstract Article PDF–2.2M

Select item 653130520.

Induction of nuclear protein-1 by thyroid hormone enhances platelet-derived growth factor A mediated angiogenesis in liver cancer

Ching-Ying Chen, Sheng-Ming Wu, Yang-Hsiang Lin, Hsiang-Cheng Chi, Syuan-Ling Lin, Chau-Ting Yeh, Wen-Yu Chuang, Kwang-Huei Lin

Theranostics. 2019; 9(8): 2361–2379. Published online 2019 Apr 13. doi: 10.7150/thno.29628

PMCID:: PMC6531305

Abstract Article PDF–4.3M

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