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Items: 1 to 20 of 77

1.
SARM1 can be a potential therapeutic target for spinal cord injury
Qicheng Lu, Benson O. A. Botchway, Yong Zhang, Tian Jin, Xuehong Liu
Cell Mol Life Sci. 2022 Mar; 79(3): 161. Published online 2022 Feb 28. doi: 10.1007/s00018-022-04195-4
PMCID:
PMC11072485
AbstractArticlePDF–836K
2.
The SARM1 TIR domain produces glycocyclic ADPR molecules as minor products
Jeremy Garb, Gil Amitai, Allen Lu, Gal Ofir, Alexander Brandis, Tevie Mehlman, Philip J. Kranzusch, Rotem Sorek
PLoS One. 2024; 19(4): e0302251. Published online 2024 Apr 18. doi: 10.1371/journal.pone.0302251
PMCID:
PMC11025887
AbstractArticlePDF–1.0M
3.
Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma
Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn
Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255
PMCID:
PMC10916866
AbstractArticlePDF–4.7M
4.
Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis
Robert S. Kiss, Jarred Chicoine, Youssef Khalil, Robert Sladek, He Chen, Alessandro Pisaturo, Cyril Martin, Jessica D. Dale, Tegan A. Brudenell, Archith Kamath, Jeffrey Kyei-Boahen, Anouar Hafiane, Girija Daliah, Célia Alecki, Tayah S. Hopes, Martin Heier, Irene A. Aligianis, Jean-Jacques Lebrun, Julie Aspden, Emanuele Paci, Anja Kerksiek, Dieter Lütjohann, Peter Clayton, Jimi C. Wills, Alex von Kriegsheim, Tommy Nilsson, Eamonn Sheridan, Mark T. Handley
J Biol Chem. 2023 Nov; 299(11): 105295. Published online 2023 Sep 28. doi: 10.1016/j.jbc.2023.105295
PMCID:
PMC10641524
AbstractArticlePDF–3.8M
5.
ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis
Alexandre Janer, Jordan L Morris, Michiel Krols, Hana Antonicka, Mari J Aaltonen, Zhen-Yuan Lin, Hanish Anand, Anne-Claude Gingras, Julien Prudent, Eric A Shoubridge
Life Sci Alliance. 2024 Jan; 7(1): e202302335. Published online 2023 Nov 6. doi: 10.26508/lsa.202302335
PMCID:
PMC10627786
AbstractArticlePDF–5.2M
6.
A phase transition reduces the threshold for nicotinamide mononucleotide-based activation of SARM1, an NAD(P) hydrolase, to physiologically relevant levels
Janneke Doedée Icso, Paul Ryan Thompson
J Biol Chem. 2023 Nov; 299(11): 105284. Published online 2023 Sep 22. doi: 10.1016/j.jbc.2023.105284
PMCID:
PMC10624580
AbstractArticlePDF–2.3M
7.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
8.
TIR-1/SARM1 inhibits axon regeneration and promotes axon degeneration
Victoria L Czech, Lauren C O'Connor, Brendan Philippon, Emily Norman, Alexandra B Byrne
eLife. 2023; 12: e80856. Published online 2023 Apr 21. doi: 10.7554/eLife.80856
PMCID:
PMC10121217
AbstractArticlePDF–3.0M
9.
Fibril treatment changes protein interactions of tau and α-synuclein in human neurons
Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson
J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888
PMCID:
PMC9978635
AbstractArticlePDF–10M
10.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
11.
Natural variants of human SARM1 cause both intrinsic and dominant loss-of-function influencing axon survival
Mirlinda Ademi, Xiuna Yang, Michael P. Coleman, Jonathan Gilley
Sci Rep. 2022; 12: 13846. Published online 2022 Aug 16. doi: 10.1038/s41598-022-18052-8
PMCID:
PMC9381744
AbstractArticlePDF–4.2M
12.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
13.
TLR4 and SARM1 modulate survival and chemoresistance in an HPV-positive cervical cancer cell line
Mirian Galliote Morale, Rodrigo Esaki Tamura, Ricardo Cintra, Natália Meneses Araújo, Luisa Lina Villa
Sci Rep. 2022; 12: 6714. Published online 2022 Apr 25. doi: 10.1038/s41598-022-09980-6
PMCID:
PMC9039070
AbstractArticlePDF–1.8M
14.
Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients
A. Joseph Bloom, Xianrong Mao, Amy Strickland, Yo Sasaki, Jeffrey Milbrandt, Aaron DiAntonio
Mol Neurodegener. 2022; 17: 1. Published online 2022 Jan 6. doi: 10.1186/s13024-021-00511-x
PMCID:
PMC8739729
AbstractArticlePDF–7.1M
15.
Enrichment of SARM1 alleles encoding variants with constitutively hyperactive NADase in patients with ALS and other motor nerve disorders
Jonathan Gilley, Oscar Jackson, Menelaos Pipis, Mehrdad A Estiar, Ammar Al-Chalabi, Matt C Danzi, Kristel R van Eijk, Stephen A Goutman, Matthew B Harms, Henry Houlden, Alfredo Iacoangeli, Julia Kaye, Leandro Lima, Queen Square Genomics, John Ravits, Guy A Rouleau, Rebecca Schüle, Jishu Xu, Stephan Züchner, Johnathan Cooper-Knock, Ziv Gan-Or, Mary M Reilly, Michael P Coleman
eLife. 2021; 10: e70905. Published online 2021 Nov 19. doi: 10.7554/eLife.70905
PMCID:
PMC8735862
AbstractArticlePDF–3.7M
16.
Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN
Yihang Li, Maria F. Pazyra-Murphy, Daina Avizonis, Mariana de Sá Tavares Russo, Sophia Tang, Chiung-Ya Chen, Yi-Ping Hsueh, Johann S. Bergholz, Tao Jiang, Jean J. Zhao, Jian Zhu, Kwang Woo Ko, Jeffrey Milbrandt, Aaron DiAntonio, Rosalind A. Segal
J Cell Biol. 2022 Feb 7; 221(2): e202106080. Published online 2021 Dec 22. doi: 10.1083/jcb.202106080
PMCID:
PMC8704956
AbstractArticlePDF–6.2M
17.
Defective Lipid Droplet–Lysosome Interaction Causes Fatty Liver Disease as Evidenced by Human Mutations in TMEM199 and CCDC115
Lars E. Larsen, Marjolein A.W. van den Boogert, Wilson A. Rios-Ocampo, Jos C. Jansen, Donna Conlon, Patrick L.E. Chong, J. Han M. Levels, Roos E. Eilers, Vinay V. Sachdev, Noam Zelcer, Tobias Raabe, Miao He, Nicholas J. Hand, Joost P.H. Drenth, David J. Rader, Eric S.G. Stroes, Dirk J. Lefeber, Johan W. Jonker, Adriaan G. Holleboom
Cell Mol Gastroenterol Hepatol. 2022; 13(2): 583–597. Published online 2021 Oct 7. doi: 10.1016/j.jcmgh.2021.09.013
PMCID:
PMC8688563
AbstractArticlePDF–2.3M
18.
Expression of sterile-α and armadillo motif containing protein (SARM) in rheumatoid arthritis monocytes correlates with TLR2-induced IL-1β and disease activity
Ryan S Thwaites, Sarah Unterberger, Giselle Chamberlain, Henry Gray, Kelsey Jordan, Kevin A Davies, Neil A Harrison, Sandra Sacre
Rheumatology (Oxford) 2021 Dec; 60(12): 5843–5853. Published online 2021 Feb 19. doi: 10.1093/rheumatology/keab162
PMCID:
PMC8645275
AbstractArticlePDF–603K
19.
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396
PMCID:
PMC8552907
AbstractArticlePDF–3.9M
20.
Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry
Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang
Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118
PMCID:
PMC8364181
AbstractArticlePDF–3.0M

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