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Items: 1 to 20 of 99

1.
Cell fixation improves performance of in situ crosslinking mass spectrometry while preserving cellular ultrastructure
Andrew R. M. Michael, Bruno C. Amaral, Kallie L. Ball, Kristen H. Eiriksson, David C. Schriemer
Nat Commun. 2024; 15: 8537. Published online 2024 Oct 2. doi: 10.1038/s41467-024-52844-y
PMCID:
PMC11447256
ArticlePDF–2.8M
2.
NUAK1 promotes metabolic dysfunction-associated steatohepatitis progression by activating Caspase 6–driven pyroptosis and inflammation
Mingwei Sheng, Shuhan Huo, Lili Jia, Yiqi Weng, Weihua Liu, Yuanbang Lin, Wenli Yu
Hepatol Commun. 2024 Jul; 8(7): e0479. Published online 2024 Jul 5. doi: 10.1097/HC9.0000000000000479
PMCID:
PMC11227355
ArticlePDF–1.8M
3.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
ArticlePDF–3.0M
4.
Caspase 6 promotes innate immune activation by functional crosstalk between RIPK1-IκBα axis in liver inflammation
Yuanbang Lin, Mingwei Sheng, Hua Qin, Peng Zhang, Chunli Wang, Wei Fu, Xiangjun Meng, Duowei Wang, Yachao Hou
Cell Commun Signal. 2023; 21: 282. Published online 2023 Oct 12. doi: 10.1186/s12964-023-01287-x
PMCID:
PMC10568785
ArticlePDF–12M
5.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
ArticlePDF–23M
6.
Dissection of pyroptosis-related prognostic signature and CASP6-mediated regulation in pancreatic adenocarcinoma: new sights to clinical decision-making
Jun Zhu, Yanlong Shi, Sheng Lan, Jingyan Wang, Fei Jiang, Caiping Tang, Yuan Cai, Ziyuan Pan, Haokun Jian, Hanlu Fang, Yewei Zhang, Fei Zhong
Apoptosis. 2023; 28(5-6): 769–782. Published online 2023 Mar 7. doi: 10.1007/s10495-023-01823-7
PMCID:
PMC10232623
ArticlePDF–8.3M
7.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
ArticlePDF–2.5M
8.
Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy
Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang
Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003
PMCID:
PMC8897022
ArticlePDF–3.0M
9.
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context
Marcel Morgenstern, Christian D. Peikert, Philipp Lübbert, Ida Suppanz, Cinzia Klemm, Oliver Alka, Conny Steiert, Nataliia Naumenko, Alexander Schendzielorz, Laura Melchionda, Wignand W.D. Mühlhäuser, Bettina Knapp, Jakob D. Busch, Sebastian B. Stiller, Stefan Dannenmaier, Caroline Lindau, Mariya Licheva, Christopher Eickhorst, Riccardo Galbusera, Ralf M. Zerbes, Michael T. Ryan, Claudine Kraft, Vera Kozjak-Pavlovic, Friedel Drepper, Sven Dennerlein, Silke Oeljeklaus, Nikolaus Pfanner, Nils Wiedemann, Bettina Warscheid
Cell Metab. 2021 Dec 7; 33(12): 2464–2483.e18. doi: 10.1016/j.cmet.2021.11.001
PMCID:
PMC8664129
Article
10.
Rare CASP6N73T variant associated with hippocampal volume exhibits decreased proteolytic activity, synaptic transmission defect, and neurodegeneration
Libin Zhou, Kwangsik Nho, Maria G. Haddad, Nicole Cherepacha, Agne Tubeleviciute-Aydin, Andy P. Tsai, Andrew J. Saykin, P. Jesper Sjöström, Andrea C. LeBlanc
Sci Rep. 2021; 11: 12695. Published online 2021 Jun 16. doi: 10.1038/s41598-021-91367-0
Correction in:
Sci Rep. 2021; 11: 16151.
PMCID:
PMC8209045
ArticlePDF–4.1M
11.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
ArticlePDF–2.2M
12.
An AMPK–caspase-6 axis controls liver damage in nonalcoholic steatohepatitis
Peng Zhao, Xiaoli Sun, Cynthia Chaggan, Zhongji Liao, Kai in Wong, Feng He, Seema Singh, Rohit Loomba, Michael Karin, Joseph L. Witztum, Alan R. Saltiel
Science. Author manuscript; available in PMC 2021 Mar 31.
Published in final edited form as: Science. 2020 Feb 7; 367(6478): 652–660. doi: 10.1126/science.aay0542
PMCID:
PMC8012106
ArticlePDF–2.5M
13.
Caspase-6-cleaved Tau fails to induce Tau hyperphosphorylation and aggregation, neurodegeneration, glial inflammation, and cognitive deficits
Anastasia Noël, Bénédicte Foveau, Andréa C. LeBlanc
Cell Death Dis. 2021 Mar; 12(3): 227. Published online 2021 Mar 1. doi: 10.1038/s41419-021-03506-0
PMCID:
PMC7921451
ArticlePDF–3.6M
14.
Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
Min Zheng, Rajendra Karki, Peter Vogel, Thirumala-Devi Kanneganti
Cell. Author manuscript; available in PMC 2021 Apr 30.
Published in final edited form as: Cell. 2020 Apr 30; 181(3): 674–687.e13. Published online 2020 Apr 15. doi: 10.1016/j.cell.2020.03.040
PMCID:
PMC7425208
ArticlePDF–2.7M
15.
Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis
Jingjiao Li, Mingquan Guo, Xiaoxu Tian, Xin Wang, Xing Yang, Ping Wu, Chengrong Liu, Zixuan Xiao, Yafei Qu, Yue Yin, Chunxia Wang, Yucai Zhang, Zhaoqin Zhu, Zhenshan Liu, Chao Peng, Tongyu Zhu, Qiming Liang
Med (N Y) 2021 Jan 15; 2(1): 99–112.e7. Published online 2020 Jul 21. doi: 10.1016/j.medj.2020.07.002
PMCID:
PMC7373048
ArticlePDF–3.8M
16.
Cross-regulation between LUBAC and caspase-1 modulates cell death and inflammation
Todd Douglas, Maya Saleh
J Biol Chem. 2020 Apr 17; 295(16): 5216–5228. Published online 2020 Mar 2. doi: 10.1074/jbc.RA119.011622
PMCID:
PMC7170516
ArticlePDF–4.0M
17.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
ArticlePDF–5.4M
18.
Proteomic analysis on structural proteins of Severe Acute Respiratory Syndrome coronavirus
Wantao Ying, Yunwei Hao, Yangjun Zhang, Wenming Peng, Ede Qin, Yun Cai, Kaihua Wei, Jie Wang, Guohui Chang, Wei Sun, Shujia Dai, Xiaohai Li, Yunping Zhu, Jianqi Li, Songfeng Wu, Lihai Guo, Jingquan Dai, Jinglan Wang, Ping Wan, Tinggui Chen, Chunjuan Du, Dong Li, Jia Wan, Xuezhang Kuai, Weihua Li, Rong Shi, Handong Wei, Cheng Cao, Man Yu, Hong Liu, Fangting Dong, Donggen Wang, Xuemin Zhang, Xiaohong Qian, Qingyu Zhu, Fuchu He
Proteomics. 2004 Feb; 4(2): 492–504. Published online 2004 Jan 15. doi: 10.1002/pmic.200300676
PMCID:
PMC7168022
ArticlePDF–191K
19.
Cell Type-Specific Cleavage of Nucleocapsid Protein by Effector Caspases during SARS Coronavirus Infection
Claudia Diemer, Martha Schneider, Judith Seebach, Janine Quaas, Gert Frösner, Hermann M. Schätzl, Sabine Gilch
J Mol Biol. 2008 Feb 8; 376(1): 23–34. Published online 2007 Dec 4. doi: 10.1016/j.jmb.2007.11.081
PMCID:
PMC7094231
ArticlePDF–1.1M
20.
MCUB regulates the molecular composition of the mitochondrial calcium uniporter channel to limit mitochondrial calcium overload during stress
Jonathan P. Lambert, Timothy S. Luongo, Dhanendra Tomar, Pooja Jadiya, Erhe Gao, Xueqian Zhang, Anna Maria Lucchese, Devin W. Kolmetzky, Neil S. Shah, John W. Elrod
Circulation. Author manuscript; available in PMC 2020 Nov 19.
Published in final edited form as: Circulation. 2019 Nov 19; 140(21): 1720–1733. Published online 2019 Sep 19. doi: 10.1161/CIRCULATIONAHA.118.037968
PMCID:
PMC6996560
ArticlePDF–1.6M

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