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Select item 95088871.

Association between EPHA5 methylation status in peripheral blood leukocytes and the risk and prognosis of gastric cancer

Xu Han, Tianyu Liu, Jiabao Zhai, Chang Liu, Wanyu Wang, Chuang Nie, Qi Wang, Xiaojie Zhu, Haibo Zhou, Wenjing Tian

PeerJ. 2022; 10: e13774. Published online 2022 Sep 21. doi: 10.7717/peerj.13774

PMCID:: PMC9508887

Abstract Article PDF–1.0M

Select item 91714112.

Physical and functional interactome atlas of human receptor tyrosine kinases

Kari Salokas, Xiaonan Liu, Tiina Öhman, Iftekhar Chowdhury, Lisa Gawriyski, Salla Keskitalo, Markku Varjosalo

EMBO Rep. 2022 Jun; 23(6): e54041. Published online 2022 Apr 5. doi: 10.15252/embr.202154041

PMCID:: PMC9171411

Abstract Article PDF–1.9M

Select item 85750253.

Deep learning model reveals potential risk genes for ADHD, especially Ephrin receptor gene EPHA5

Lu Liu, Xikang Feng, Haimei Li, Shuai Cheng Li, Qiujin Qian, Yufeng Wang

Brief Bioinform. 2021 Nov; 22(6): bbab207. Published online 2021 Jun 9. doi: 10.1093/bib/bbab207

PMCID:: PMC8575025

Abstract Article PDF–1.1M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 78349945.

EPHA5 mutations predict survival after immunotherapy in lung adenocarcinoma

Zhiming Chen, Ji Chen, Dandan Ren, Jiao Zhang, Ying Yang, Henghui Zhang, Beibei Mao, Haitao Ma

Aging (Albany NY) 2021 Jan 15; 13(1): 598–618. Published online 2020 Dec 3. doi: 10.18632/aging.202169

PMCID:: PMC7834994

Abstract Article PDF–2.6M

Select item 74273276.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 71633837.

Genetic variation in EPHA contributes to sensitivity to paclitaxel‐induced peripheral neuropathy

Lauren A. Marcath, Kelley M. Kidwell, Kiran Vangipuram, Christina L. Gersch, James M. Rae, Monika L. Burness, Jennifer J. Griggs, Catherine Van Poznak, Daniel F. Hayes, Ellen M. Lavoie Smith, N. Lynn Henry, Andreas S. Beutler, Daniel L. Hertz

Br J Clin Pharmacol. 2020 May; 86(5): 880–890. Published online 2020 Feb 4. doi: 10.1111/bcp.14192

PMCID:: PMC7163383

Abstract Article PDF–1001K

Select item 67828898.

Regulation of Learning by EphA Receptors: a Protein Targeting Study

R. Gerlai, N. Shinsky, A. Shih, P. Williams, J. Winer, M. Armanini, B. Cairns, J. Winslow, W.-Q. Gao, H. S. Phillips

J Neurosci. 1999 Nov 1; 19(21): 9538–9549. doi: 10.1523/JNEUROSCI.19-21-09538.1999

PMCID:: PMC6782889

Abstract Article PDF–438K

Select item 67827679.

A Role for the Eph Ligand Ephrin-A3 in Entorhino-Hippocampal Axon Targeting

Eckart Stein, Nicolai E. Savaskan, Olaf Ninnemann, Robert Nitsch, Renping Zhou, Thomas Skutella

J Neurosci. 1999 Oct 15; 19(20): 8885–8893. doi: 10.1523/JNEUROSCI.19-20-08885.1999

Correction in:: J Neurosci. 2012 May 16; 32(20): 7102.

PMCID:: PMC6782767

Abstract Article PDF–1.2M

Select item 677813710.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 642983011.

Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer

Sean P. Kennedy, Jeremy Z. R. Han, Neil Portman, Max Nobis, Jordan F. Hastings, Kendelle J. Murphy, Sharissa L. Latham, Antonia L. Cadell, Dushan Miladinovic, Gabriella R. Marriott, Yolande E. I. O’Donnell, Robert F. Shearer, James T. Williams, Amaya Garcia Munoz, Thomas R. Cox, D. Neil Watkins, Darren N. Saunders, Paul Timpson, Elgene Lim, Walter Kolch, David R. Croucher

Breast Cancer Res. 2019; 21: 43. Published online 2019 Mar 21. doi: 10.1186/s13058-019-1127-y

PMCID:: PMC6429830

Abstract Article PDF–3.1M

Select item 629825412.

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

Emmy Van Quickelberghe, Delphine De Sutter, Geert van Loo, Sven Eyckerman, Kris Gevaert

Sci Data. 2018; 5: 180289. Published online 2018 Dec 18. doi: 10.1038/sdata.2018.289

PMCID:: PMC6298254

Abstract Article PDF–1.4M

Select item 566346513.

A Global Analysis of The Receptor Tyrosine Kinase – Protein Phosphatase Interactome

Zhong Yao, Katelyn Darowski, Nicole St-Denis, Victoria Wong, Fabian Offensperger, Annabel Villedieu, Shahreen Amin, Ramy Malty, Hiroyuki Aoki, Hongbo Guo, Yang Xu, Caterina Iorio, Max Kotlyar, Andrew Emili, Igor Jurisica, Benjamin G Neel, Mohan Babu, Anne-Claude Gingras, Igor Stagljar

Mol Cell. Author manuscript; available in PMC 2017 Oct 31.

Published in final edited form as: Mol Cell. 2017 Jan 19; 65(2): 347–360. Published online 2017 Jan 5. doi: 10.1016/j.molcel.2016.12.004

PMCID:: PMC5663465

Abstract Article PDF–2.1M

Select item 553161114.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 544785715.

Decreased expression of EphA5 is associated with Fuhrman nuclear grade and pathological tumour stage in ccRCC

Xiaolin Wang, Haifei Xu, Zhijun Wu, Xiao Chen, Jiandong Wang

Int J Exp Pathol. 2017 Feb; 98(1): 34–39. Published online 2017 Apr 19. doi: 10.1111/iep.12219

PMCID:: PMC5447857

Abstract Article PDF–639K

Select item 512322216.

EphA5 protein, a potential marker for distinguishing histological grade and prognosis in ovarian serous carcinoma

Xiao Chen, Xuan Wang, Xue Wei, Jiandong Wang

J Ovarian Res. 2016; 9: 83. Published online 2016 Nov 25. doi: 10.1186/s13048-016-0292-1

PMCID:: PMC5123222

Abstract Article PDF–1.6M

Select item 461721117.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 436724418.

Receptor Tyrosine Kinase EphA5 Is a Functional Molecular Target in Human Lung Cancer

Fernanda I. Staquicini, Ming D. Qian, Ahmad Salameh, Andrey S. Dobroff, Julianna K. Edwards, Daniel F. Cimino, Benjamin J. Moeller, Patrick Kelly, Maria I. Nunez, Ximing Tang, Diane D. Liu, J. Jack Lee, Waun Ki Hong, Fortunato Ferrara, Andrew R. M. Bradbury, Roy R. Lobb, Martin J. Edelman, Richard L. Sidman, Ignacio I. Wistuba, Wadih Arap, Renata Pasqualini

J Biol Chem. 2015 Mar 20; 290(12): 7345–7359. Published online 2015 Jan 26. doi: 10.1074/jbc.M114.630525

PMCID:: PMC4367244

Abstract Article PDF–4.4M

Select item 430761719.

Downregulation of EphA5 by promoter methylation in human prostate cancer

Shibao Li, Yingfeng Zhu, Chunguang Ma, Zhenhua Qiu, Xinju Zhang, Zhihua Kang, Zhiyuan Wu, Hua Wang, Xiao Xu, Hu Zhang, Guoqiang Ren, Jianmin Tang, Xiangyu Li, Ming Guan

BMC Cancer. 2015; 15: 18. Published online 2015 Jan 22. doi: 10.1186/s12885-015-1025-3

PMCID:: PMC4307617

Abstract Article PDF–3.0M

Select item 384475120.

A TrkB/EphrinA Interaction Controls Retinal Axon Branching and Synaptogenesis

Katharine J. M. Marler, Elena Becker-Barroso, Albert Martínez, Marta Llovera, Corinna Wentzel, Subathra Poopalasundaram, Robert Hindges, Eduardo Soriano, Joan Comella, Uwe Drescher

J Neurosci. 2008 Nov 26; 28(48): 12700–12712. doi: 10.1523/JNEUROSCI.1915-08.2008

PMCID:: PMC3844751

Abstract Article PDF–845K

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