PMC Links for GEO Profiles (Select 130769113) - PMC

Links from GEO Profiles

Items: 1 to 20 of 120

<< First< Prev

Page of 6

Select item 111439321.

C3aR-initiated signaling is a critical mechanism of podocyte injury in membranous nephropathy

Qi Zhang, Sofia Bin, Kelly Budge, Astgik Petrosyan, Valentina Villani, Paola Aguiari, Coralien Vink, Jack Wetzels, Hasmik Soloyan, Gaetano La Manna, Manuel Alfredo Podestà, Paolo Molinari, Sargis Sedrakyan, Kevin V. Lemley, Roger E. De Filippo, Laura Perin, Paolo Cravedi, Stefano Da Sacco

JCI Insight. 2024 Feb 22; 9(4): e172976. Published online 2024 Jan 16. doi: 10.1172/jci.insight.172976

PMCID:: PMC11143932

Abstract Article PDF–7.3M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107969793.

Functional profiling of the G protein-coupled receptor C3aR1 reveals ligand-mediated biased agonism

Pedro Rodriguez, Lauren J. Laskowski, Jean Pierre Pallais, Hailey A. Bock, Natalie G. Cavalco, Emilie I. Anderson, Maggie M. Calkins, Maria Razzoli, Yuk Y. Sham, John D. McCorvy, Alessandro Bartolomucci

J Biol Chem. 2024 Jan; 300(1): 105549. Published online 2023 Dec 10. doi: 10.1016/j.jbc.2023.105549

PMCID:: PMC10796979

Abstract Article PDF–2.2M

Select item 102667934.

Complement C3aR depletion reverses HIF-1α–induced metabolic impairment and enhances microglial response to Aβ pathology

Manasee Gedam, Michele M. Comerota, Nicholas E. Propson, Tao Chen, Feng Jin, Meng C. Wang, Hui Zheng

J Clin Invest. 2023 Jun 15; 133(12): e167501. Published online 2023 Jun 15. doi: 10.1172/JCI167501

PMCID:: PMC10266793

Abstract Article PDF–18M

Select item 101104185.

Microglia refine developing retinal astrocytic and vascular networks through the complement C3/C3aR axis

Gopalan Gnanaguru, Steven J. Tabor, Gracia M. Bonilla, Ruslan Sadreyev, Kentaro Yuda, Jörg Köhl, Kip M. Connor

Development. 2023 Mar 1; 150(5): dev201047. Published online 2023 Mar 1. doi: 10.1242/dev.201047

PMCID:: PMC10110418

Abstract Article

Select item 97801776.

Neutrophil complement receptor signaling is required for BAFF-dependent humoral responses in mice

Arun Cumpelik, Evan Cody, Samuel Mon-Wei Yu, Emilie K. Grasset, David Dominguez-Sola, Andrea Cerutti, Peter S. Heeger

J Immunol. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: J Immunol. 2023 Jan 1; 210(1): 19–23. doi: 10.4049/jimmunol.2200410

PMCID:: PMC9780177

Abstract Article PDF–1.1M

Select item 95785937.

Genome-scale CRISPR screening reveals that C3aR signaling is critical for rapid capture of fungi by macrophages

Allison Cohen, Edwin E. Jeng, Mark Voorhies, Jane Symington, Nebat Ali, Rosa A. Rodriguez, Michael C. Bassik, Anita Sil

PLoS Pathog. 2022 Sep; 18(9): e1010237. Published online 2022 Sep 29. doi: 10.1371/journal.ppat.1010237

PMCID:: PMC9578593

Abstract Article PDF–4.3M

Select item 93517148.

C3aR Signaling Inhibits NK-cell Infiltration into the Tumor Microenvironment in Mouse Models

Saravanan Nandagopal, Caiyun G. Li, Yu Xu, Quaovi H. Sodji, Edward E. Graves, Amato J. Giaccia

Cancer Immunol Res. Author manuscript; available in PMC 2022 Aug 4.

Published in final edited form as: Cancer Immunol Res. 2022 Feb; 10(2): 245–258. Published online 2021 Nov 24. doi: 10.1158/2326-6066.CIR-21-0435

PMCID:: PMC9351714

Abstract Article PDF–1.8M

Select item 87186879.

C3a Receptor Signaling Inhibits Neurodegeneration Induced by Neonatal Hypoxic-Ischemic Brain Injury

Andrea Pozo-Rodrigálvarez, YiXian Li, Anna Stokowska, Jingyun Wu, Verena Dehm, Hana Sourkova, Harry Steinbusch, Carina Mallard, Henrik Hagberg, Milos Pekny, Marcela Pekna

Front Immunol. 2021; 12: 768198. Published online 2021 Dec 17. doi: 10.3389/fimmu.2021.768198

PMCID:: PMC8718687

Abstract Article PDF–30M

Select item 855133110.

Lung mesenchymal stromal cells influenced by Th2 cytokines mobilize neutrophils and facilitate metastasis by producing complement C3

Zhiyuan Zheng, Ya-nan Li, Shanfen Jia, Mengting Zhu, Lijuan Cao, Min Tao, Jingting Jiang, Shenghua Zhan, Yongjing Chen, Ping-Jin Gao, Weiguo Hu, Ying Wang, Changshun Shao, Yufang Shi

Nat Commun. 2021; 12: 6202. Published online 2021 Oct 27. doi: 10.1038/s41467-021-26460-z

PMCID:: PMC8551331

Abstract Article PDF–3.9M

Select item 842527611.

Complement activation promoted by the lectin pathway mediates C3aR-dependent sarcoma progression and immunosuppression

Elena Magrini, Sabrina Di Marco, Sarah N. Mapelli, Chiara Perucchini, Fabio Pasqualini, Alessia Donato, Maria de la Luz Guevara Lopez, Roberta Carriero, Andrea Ponzetta, Piergiuseppe Colombo, Ferdinando Cananzi, Domenico Supino, Edimara S. Reis, Clelia Peano, Antonio Inforzato, Sebastien Jaillon, Andrea Doni, John D. Lambris, Alberto Mantovani, Cecilia Garlanda

Nat Cancer. Author manuscript; available in PMC 2021 Sep 8.

Published in final edited form as: Nat Cancer. 2021 Feb; 2(2): 218–232. Published online 2021 Feb 18. doi: 10.1038/s43018-021-00173-0

PMCID:: PMC8425276

Abstract Article PDF–5.4M

Select item 831323912.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 829755613.

Dynamic regulation of B cell Complement Signaling is Integral to Germinal Center Responses

Arun Cumpelik, David Heja, Yuan Hu, Gabriele Varano, Farideh Ordikhani, Mark P. Roberto, Zhengxiang He, Dirk Homann, Sergio A. Lira, David Dominguez-Sola, Peter S. Heeger

Nat Immunol. Author manuscript; available in PMC 2021 Nov 24.

Published in final edited form as: Nat Immunol. 2021 Jun; 22(6): 757–768. Published online 2021 May 24. doi: 10.1038/s41590-021-00926-0

PMCID:: PMC8297556

Abstract Article PDF–4.9M

Select item 818500314.

The C5a/C5a receptor 1 axis controls tissue neovascularization through CXCL4 release from platelets

Henry Nording, Lasse Baron, David Haberthür, Frederic Emschermann, Matthias Mezger, Manuela Sauter, Reinhard Sauter, Johannes Patzelt, Kai Knoepp, Anne Nording, Moritz Meusel, Roza Meyer-Saraei, Ruslan Hlushchuk, Daniel Sedding, Oliver Borst, Ingo Eitel, Christian M. Karsten, Robert Feil, Bernd Pichler, Jeanette Erdmann, Admar Verschoor, Emmanouil Chavakis, Triantafyllos Chavakis, Philipp von Hundelshausen, Jörg Köhl, Meinrad Gawaz, Harald F. Langer

Nat Commun. 2021; 12: 3352. Published online 2021 Jun 7. doi: 10.1038/s41467-021-23499-w

PMCID:: PMC8185003

Abstract Article PDF–4.8M

Select item 815032715.

C3 Drives Inflammatory Skin Carcinogenesis Independently of C5

William D. Jackson, Alessandro Gulino, Liliane Fossati-Jimack, Rocio Castro Seoane, Kunyuan Tian, Katie Best, Jörg Köhl, Beatrice Belmonte, Jessica Strid, Marina Botto

J Invest Dermatol. 2021 Feb; 141(2): 404–414.e6. doi: 10.1016/j.jid.2020.06.025

PMCID:: PMC8150327

Abstract Article PDF–4.5M

Select item 798641216.

Complement and Chlamydia psittaci: Early Complement-Dependent Events Are Important for DC Migration and Protection During Mouse Lung Infection

Martin Kohn, Christian Lanfermann, Robert Laudeley, Silke Glage, Claudia Rheinheimer, Andreas Klos

Front Immunol. 2021; 12: 580594. Published online 2021 Mar 9. doi: 10.3389/fimmu.2021.580594

PMCID:: PMC7986412

Abstract Article PDF–4.7M

Select item 793695417.

The complement C3-C3aR pathway mediates microglia-astrocyte interaction following status epilepticus

Yujia Wei, Tingjun Chen, Dale B. Bosco, Manling Xie, Jiaying Zheng, Aastha Dheer, Yanlu Ying, Qian Wu, Vanda A. Lennon, Long-Jun Wu

Glia. Author manuscript; available in PMC 2021 May 1.

Published in final edited form as: Glia. 2021 May; 69(5): 1155–1169. Published online 2020 Dec 14. doi: 10.1002/glia.23955

PMCID:: PMC7936954

Abstract Article PDF–3.6M

Select item 782068318.

Endothelial progenitor cell transplantation alleviated ischemic brain injury via inhibiting C3/C3aR pathway in mice

Yuanyuan Ma, Lu Jiang, Liping Wang, Yongfang Li, Yanqun Liu, Wenjing Lu, Rubing Shi, Linyuan Zhang, Zongjie Fu, Meijie Qu, Yingling Liu, Yongting Wang, Zhijun Zhang, Guo-Yuan Yang

J Cereb Blood Flow Metab. 2020 Dec; 40(12): 2374–2386. Published online 2019 Dec 22. doi: 10.1177/0271678X19892777

PMCID:: PMC7820683

Abstract Article PDF–1.8M

Select item 777335219.

Endothelial C3a receptor mediates vascular inflammation and blood-brain barrier permeability during aging

Nicholas E. Propson, Ethan R. Roy, Alexandra Litvinchuk, Jörg Köhl, Hui Zheng

J Clin Invest. 2021 Jan 4; 131(1): e140966. Published online 2021 Jan 4. doi: 10.1172/JCI140966

PMCID:: PMC7773352

Abstract Article PDF–4.3M

Select item 770359720.

Complement as Prognostic Biomarker and Potential Therapeutic Target in Renal Cell Carcinoma.

Britney Reese, Ashok Silwal, Elizabeth Daugherity, Michael Daugherity, Mahshid Arabi, Pierce Daly, Yvonne Paterson, Layton Woolford, Alana Christie, Roy Elias, James Brugarolas, Tao Wang, Magdalena Karbowniczek, Maciej M. Markiewski

J Immunol. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: J Immunol. 2020 Dec 1; 205(11): 3218–3229. Published online 2020 Nov 6. doi: 10.4049/jimmunol.2000511

PMCID:: PMC7703597

Abstract Article PDF–3.2M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from GEO Profiles

Items: 1 to 20 of 120

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity