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Items: 1 to 20 of 43

1.
Expression of VISTA regulated via IFN-γ governs endogenous T-cell function and exhibits correlation with the efficacy of CD19 CAR-T cell treated B-malignant mice
Donghai Tang, Li Zhao, Fen Yan, Chunxiao Ren, Kailin Xu, Kai Zhao
J Immunother Cancer. 2024; 12(6): e008364. Published online 2024 Jun 25. doi: 10.1136/jitc-2023-008364
PMCID:
PMC11202651
AbstractArticlePDF–22M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
VISTA promotes the metabolism and differentiation of myeloid-derived suppressor cells by STAT3 and polyamine-dependent mechanisms
Keman Zhang, Amin Zakeri, Tyler Alban, Juan Dong, Hieu M. Ta, Ajay H. Zalavadia, Andrelie Branicky, Haoxin Zhao, Ivan Juric, Hanna Husich, Prerana B. Parthasarathy, Amit Rupani, Judy A. Drazba, Abhishek A. Chakraborty, Stanley Ching-Cheng Huang, Timothy Chan, Stefanie Avril, Li Lily Wang
Cell Rep. Author manuscript; available in PMC 2024 Feb 8.
Published in final edited form as: Cell Rep. 2024 Jan 23; 43(1): 113661. Published online 2024 Jan 3. doi: 10.1016/j.celrep.2023.113661
PMCID:
PMC10851928
AbstractArticlePDF–2.5M
4.
PD-1H/VISTA mediates immune evasion in acute myeloid leukemia
Tae Kon Kim, Xue Han, Qianni Hu, Esten N. Vandsemb, Carly M. Fielder, Junshik Hong, Kwang Woon Kim, Emily F. Mason, R. Skipper Plowman, Jun Wang, Qi Wang, Jian-Ping Zhang, Ti Badri, Miguel F. Sanmamed, Linghua Zheng, Tianxiang Zhang, Jude Alawa, Sang Won Lee, Amer M. Zeidan, Stephanie Halene, Manoj M. Pillai, Namrata S. Chandhok, Jun Lu, Mina L. Xu, Steven D. Gore, Lieping Chen
J Clin Invest. 2024 Feb 1; 134(3): e164325. Published online 2024 Feb 1. doi: 10.1172/JCI164325
PMCID:
PMC10836799
AbstractArticlePDF–3.9M
5.
The checkpoint inhibitor PD-1H/VISTA controls osteoclast-mediated multiple myeloma bone disease
Jing Fu, Shirong Li, Huihui Ma, Jun Yang, Gabriel M. Pagnotti, Lewis M. Brown, Stephen J. Weiss, Markus Y. Mapara, Suzanne Lentzsch
Nat Commun. 2023; 14: 4271. Published online 2023 Jul 17. doi: 10.1038/s41467-023-39769-8
PMCID:
PMC10352288
AbstractArticlePDF–11M
6.
VISTA (PD-1H) Is a Crucial Immune Regulator to Limit Pulmonary Fibrosis
Sang-Hun Kim, Taylor S. Adams, Qianni Hu, Hyeon Jun Shin, Ganghee Chae, Sang Eun Lee, Lokesh Sharma, Hyuk-Kwon Kwon, Francis Y. Lee, Hong-Jai Park, Won Jae Huh, Edward Manning, Naftali Kaminski, Maor Sauler, Lieping Chen, Jin Woo Song, Tae Kon Kim, Min-Jong Kang
Am J Respir Cell Mol Biol. 2023 Jul; 69(1): 22–33. Published online 2022 Nov 30. doi: 10.1165/rcmb.2022-0219OC
PMCID:
PMC10324045
AbstractArticlePDF–4.5M
7.
Negative Immune Checkpoint Protein, VISTA, Regulates the CD4+ Treg Population During Sepsis Progression to Promote Acute Sepsis Recovery and Survival
Chyna C. Gray, Bethany Biron-Girard, Michelle E. Wakeley, Chun-Shiang Chung, Yaping Chen, Yael Quiles-Ramirez, Jessica D. Tolbert, Alfred Ayala
Front Immunol. 2022; 13: 861670. Published online 2022 Mar 24. doi: 10.3389/fimmu.2022.861670
PMCID:
PMC8988198
AbstractArticlePDF–5.8M
8.
Ablation of T cell–associated PD-1H enhances functionality and promotes adoptive immunotherapy
Li Hu, Ling Chen, Zexiu Xiao, Xu Zheng, Yuangui Chen, Na Xian, Christina Cho, Liqun Luo, Gangxiong Huang, Lieping Chen
JCI Insight. 2022 Jan 25; 7(2): e148247. Published online 2022 Jan 25. doi: 10.1172/jci.insight.148247
PMCID:
PMC8855794
AbstractArticlePDF–6.3M
9.
Kidney VISTA prevents IFN-γ/IL-9 axis–mediated tubulointerstitial fibrosis after acute glomerular injury
Min-Gang Kim, Donghwan Yun, Chae Lin Kang, Minki Hong, Juhyeon Hwang, Kyung Chul Moon, Chang Wook Jeong, Cheol Kwak, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo, Yon Su Kim, Dong-Sup Lee, Seung Seok Han
J Clin Invest. 2022 Jan 4; 132(1): e151189. Published online 2022 Jan 4. doi: 10.1172/JCI151189
PMCID:
PMC8718152
AbstractArticlePDF–5.3M
10.
VISTA regulates microglia homeostasis and myelin phagocytosis, and is associated with MS lesion pathology
Malte Borggrewe, Susanne M. Kooistra, Evelyn M. Wesseling, Fenja L. Gierschek, Maaike L. Brummer, Elizabeth C. Nowak, Tiago Medeiros-Furquim, Tegan A. Otto, Sam W. Lee, Randolph J. Noelle, Bart J. L. Eggen, Jon D. Laman
Acta Neuropathol Commun. 2021; 9: 91. Published online 2021 May 18. doi: 10.1186/s40478-021-01186-7
PMCID:
PMC8130385
AbstractArticlePDF–3.1M
11.
Single-cell RNA-Seq reveals the transcriptional landscape and heterogeneity of skin macrophages in Vsir-/- murine psoriasis
Chenxin Qie, Jingwei Jiang, Wanmei Liu, Xinlei Hu, Wenting Chen, Xiaoxue Xie, Jun Liu
Theranostics. 2020; 10(23): 10483–10497. Published online 2020 Aug 21. doi: 10.7150/thno.45614
PMCID:
PMC7482809
AbstractArticlePDF–3.5M
12.
VISTA is a checkpoint regulator for naïve T cell quiescence and peripheral tolerance
Mohamed A. ElTanbouly, Yanding Zhao, Elizabeth Nowak, Jiannan Li, Evelien Schaafsma, Isabelle Le Mercier, Sabrina Ceeraz, J. Louise Lines, Changwei Peng, Catherine Carriere, Xin Huang, Maria Day, Brent Koehn, Sam W. Lee, Milagros Silva Morales, Kristin A. Hogquist, Stephen C. Jameson, Daniel Mueller, Jay Rothstein, Bruce R. Blazar, Chao Cheng, Randolph J. Noelle
Science. Author manuscript; available in PMC 2020 Jul 30.
Published in final edited form as: Science. 2020 Jan 17; 367(6475): eaay0524. doi: 10.1126/science.aay0524
PMCID:
PMC7391053
AbstractArticlePDF–1.7M
13.
Defining the Signature of VISTA on Myeloid Cell Chemokine Responsiveness
Thomas W. K. Broughton, Mohamed A. ElTanbouly, Evelien Schaafsma, Jie Deng, Aurélien Sarde, Walburga Croteau, Jiannan Li, Elizabeth C. Nowak, Rodwell Mabaera, Nicole C. Smits, Anna Kuta, Randolph J. Noelle, J. Louise Lines
Front Immunol. 2019; 10: 2641. Published online 2019 Nov 19. doi: 10.3389/fimmu.2019.02641
PMCID:
PMC6877598
AbstractArticlePDF–1.3M
14.
Immune checkpoint protein VISTA regulates antitumor immunity by controlling myeloid cell–mediated inflammation and immunosuppression
Wenwen Xu, Juan Dong, Yongwei Zheng, Juan Zhou, Ying Yuan, Hieu Minh Ta, Halli E. Miller, Michael Olson, Kamalakannan Rajasekaran, Marc S. Ernstoff, Demin Wang, Subramaniam Malarkannan, Li Wang
Cancer Immunol Res. Author manuscript; available in PMC 2020 Mar 1.
Published in final edited form as: Cancer Immunol Res. 2019 Sep; 7(9): 1497–1510. Published online 2019 Jul 24. doi: 10.1158/2326-6066.CIR-18-0489
PMCID:
PMC6726548
AbstractArticlePDF–2.5M
15.
VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases
Malte Borggrewe, Corien Grit, Wilfred F. A. Den Dunnen, Saskia M. Burm, Jeffrey J. Bajramovic, Randolph J. Noelle, Bart J. L. Eggen, Jon D. Laman
Glia. 2018 Dec; 66(12): 2645–2658. Published online 2018 Oct 11. doi: 10.1002/glia.23517
PMCID:
PMC6585704
AbstractArticlePDF–11M
16.
CD71+VISTA+ erythroid cells promote the development and function of regulatory T cells through TGF-β
Shima Shahbaz, Najmeh Bozorgmehr, Petya Koleva, Afshin Namdar, Juan Jovel, Roy A. Fava, Shokrollah Elahi
PLoS Biol. 2018 Dec; 16(12): e2006649. Published online 2018 Dec 14. doi: 10.1371/journal.pbio.2006649
PMCID:
PMC6310287
AbstractArticlePDF–3.3M
17.
A crucial role of the PD-1H coinhibitory receptor in suppressing experimental asthma
Huafeng Liu, Xin Li, Li Hu, Min Zhu, Bailin He, Liqun Luo, Lieping Chen
Cell Mol Immunol. 2018 Sep; 15(9): 838–845. Published online 2017 May 8. doi: 10.1038/cmi.2017.16
Correction in:
Cell Mol Immunol. 2023 Jul; 20(7): 857.
PMCID:
PMC6203798
AbstractArticlePDF–4.2M
18.
VISTA deficiency attenuates antibody-induced arthritis and alters macrophage gene expression in response to simulated immune complexes
Sabrina Ceeraz, Susan K. Eszterhas, Petra A. Sergent, David A. Armstrong, Alix Ashare, Thomas Broughton, Li Wang, Dov Pechenick, Christopher M. Burns, Randolph J. Noelle, Matthew P. Vincenti, Roy A. Fava
Arthritis Res Ther. 2017; 19: 270. Published online 2017 Dec 8. doi: 10.1186/s13075-017-1474-y
PMCID:
PMC5721690
AbstractArticlePDF–1.9M
19.
Programmed death one homolog maintains the pool size of regulatory T cells by promoting their differentiation and stability
Qi Wang, Jianwei He, Dallas B. Flies, Liqun Luo, Lieping Chen
Sci Rep. 2017; 7: 6086. Published online 2017 Jul 20. doi: 10.1038/s41598-017-06410-w
Correction in:
Sci Rep. 2023; 13: 11603.
PMCID:
PMC5519767
AbstractArticlePDF–1.8M
20.
Immune-checkpoint protein VISTA critically regulates the IL-23/IL-17 inflammatory axis
Na Li, Wenwen Xu, Ying Yuan, Natarajan Ayithan, Yasutomo Imai, Xuesong Wu, Halli Miller, Michael Olson, Yunfeng Feng, Yina H. Huang, Mary Jo Turk, Samuel T. Hwang, Subramaniam Malarkannan, Li Wang
Sci Rep. 2017; 7: 1485. Published online 2017 May 3. doi: 10.1038/s41598-017-01411-1
Correction in:
Sci Rep. 2018; 8: 4054.
PMCID:
PMC5431161
AbstractArticlePDF–1.7M

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