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Select item 113208491.

The SEMA3F-NRP1/NRP2 axis is a key factor in the acquisition of invasive traits in in situ breast ductal carcinoma

Núria Moragas, Patricia Fernandez-Nogueira, Leire Recalde-Percaz, Jamie L. Inman, Anna López-Plana, Helga Bergholtz, Aleix Noguera-Castells, Pedro J. del Burgo, Xieng Chen, Therese Sorlie, Pere Gascón, Paloma Bragado, Mina Bissell, Neus Carbó, Gemma Fuster

Breast Cancer Res. 2024; 26: 122. Published online 2024 Aug 13. doi: 10.1186/s13058-024-01871-0

PMCID:: PMC11320849

Abstract Article PDF–9.5M

Select item 109168662.

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma

Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn

Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255

PMCID:: PMC10916866

Abstract Article PDF–4.7M

Select item 103831773.

Tumor Necrosis Factor and Interleukin-1β Upregulate NRP2 Expression and Promote SARS-CoV-2 Proliferation

Michinori Ishitoku, Sho Mokuda, Kei Araki, Hirofumi Watanabe, Hiroki Kohno, Tomohiro Sugimoto, Yusuke Yoshida, Takemasa Sakaguchi, Junya Masumoto, Shintaro Hirata, Eiji Sugiyama

Viruses. 2023 Jul; 15(7): 1498. Published online 2023 Jul 3. doi: 10.3390/v15071498

PMCID:: PMC10383177

Abstract Article PDF–2.5M

Select item 102374224.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 97423005.

Proteomic analysis of diabetes genetic risk scores identifies complement C2 and neuropilin-2 as predictors of type 2 diabetes: the Atherosclerosis Risk in Communities (ARIC) Study

Brian T. Steffen, Weihong Tang, Pamela L. Lutsey, Ryan T. Demmer, Elizabeth Selvin, Kunihiro Matsushita, Alanna C. Morrison, Weihua Guan, Mary R. Rooney, Faye L. Norby, Nathan Pankratz, David Couper, James S. Pankow

Diabetologia. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: Diabetologia. 2023 Jan; 66(1): 105–115. Published online 2022 Oct 4. doi: 10.1007/s00125-022-05801-7

PMCID:: PMC9742300

Abstract Article PDF–868K

Select item 96677146.

Neuropilin 2 Is a Novel Regulator of Distal Colon Contractility

George Lambrinos, Vivian Cristofaro, Kristine Pelton, Alexander Bigger-Allen, Claire Doyle, Evalynn Vasquez, Diane R. Bielenberg, Maryrose P. Sullivan, Rosalyn M. Adam

Am J Pathol. 2022 Nov; 192(11): 1592–1603. doi: 10.1016/j.ajpath.2022.07.013

PMCID:: PMC9667714

Abstract Article PDF–3.5M

Select item 96355957.

MUC16 Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma by Upregulating NRP2-Associated Cell Adhesion

Saravanakumar Marimuthu, Imayavaramban Lakshmanan, Sakthivel Muniyan, Shailendra K. Gautam, Rama Krishna Nimmakayala, Sanchita Rauth, Pranita Atri, Ashu Shah, Namita Bhyravbhatla, Kavita Mallya, Paul M. Grandgenett, Michael A. Hollingsworth, Kaustubh Datta, Maneesh Jain, Moorthy P. Ponnusamy, Surinder K. Batra

Mol Cancer Res. Author manuscript; available in PMC 2022 Nov 4.

Published in final edited form as: Mol Cancer Res. 2022 Aug 5; 20(8): 1208–1221. doi: 10.1158/1541-7786.MCR-21-0888

PMCID:: PMC9635595

Abstract Article PDF–3.5M

Select item 94697618.

Photochemical Identification of Auxiliary SARS-Cov-2 Host-Entry Factors using μMap

Saori Suzuki, Jacob B. Geri, Steve D. Knutson, Harris Bell-Temin, Tomokazu Tamura, David F. Fernández, Gabby H. Lovett, Nicholas A. Till, Brigitte L. Heller, Jinchao Guo, David W. C. MacMillan, Alexander Ploss

J Am Chem Soc. Author manuscript; available in PMC 2024 Jan 25.

Published in final edited form as: J Am Chem Soc. 2022 Sep 14; 144(36): 16604–16611. Published online 2022 Sep 1. doi: 10.1021/jacs.2c06806

PMCID:: PMC9469761

Abstract Article PDF–1.4M

Select item 93935109.

Quantitative Assessment of the Apical and Basolateral Membrane Expression of VEGFR2 and NRP2 in VEGF-A-stimulated Cultured Human Umbilical Vein Endothelial Cells

Esmeralda K. Bosma, Shahan Darwesh, Jia Y. Zheng, Cornelis J.F. van Noorden, Reinier O. Schlingemann, Ingeborg Klaassen

J Histochem Cytochem. 2022 Aug; 70(8): 557–569. Published online 2022 Jul 25. doi: 10.1369/00221554221115767

PMCID:: PMC9393510

Abstract Article PDF–6.1M

Select item 935596310.

Cell-based receptor discovery identifies host factors specifically targeted by the SARS CoV-2 spike

Bushra Husain, Kobe Yuen, Dawei Sun, Shengya Cao, Jian Payandeh, Nadia Martinez-Martin

Commun Biol. 2022; 5: 788. Published online 2022 Aug 5. doi: 10.1038/s42003-022-03695-0

PMCID:: PMC9355963

Abstract Article PDF–3.0M

Select item 924795111.

Role of Neuropilin-2-mediated signaling axis in cancer progression and therapy resistance

Ridwan Islam, Juhi Mishra, Sanika Bodas, Sreyashi Bhattacharya, Surinder K. Batra, Samikshan Dutta, Kaustubh Datta

Cancer Metastasis Rev. 2022; 41(3): 771–787. Published online 2022 Jul 1. doi: 10.1007/s10555-022-10048-0

PMCID:: PMC9247951

Abstract Article PDF–1.3M

Select item 923162312.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 916194513.

Effects of silencing neuropilin-2 on proliferation, migration, and invasion of colorectal cancer HT-29

Qi-Qi Zhan, Qian-Yu Liu, Xin Yang, Yu-Hui Ge, Lei Xu, Guan-Yi Ding, Shang Guo, Bing Zhu, Wei-Guo Xu

Bioengineered. 2022; 13(4): 11042–11049. Published online 2022 Apr 27. doi: 10.1080/21655979.2022.2068363

PMCID:: PMC9161945

Abstract Article PDF–4.1M

Select item 911973614.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 880663615.

lncRNA RMRP predicts poor prognosis and mediates tumor progression of esophageal squamous cell carcinoma by regulating miR-613/ neuropilin 2 (NRP2) axis

Zhen Xie, Shuai Liu, Shicheng Chu, Yiqun Liu, Bingtao Huang, Qingguang Zhang

Bioengineered. 2021; 12(1): 6913–6922. Published online 2021 Sep 13. doi: 10.1080/21655979.2021.1974656

PMCID:: PMC8806636

Abstract Article PDF–1.2M

Select item 860621816.

Analysis of PLXNA1, NRP1, and NRP2 variants in a cohort of patients with isolated hypogonadotropic hypogonadism

Meichao Men, Dan‐Na Chen, Jia‐Da Li, Xinying Wang, Wang Zeng, Fang Jiang, Ruizhi Zheng, Wenting Dai

Mol Genet Genomic Med. 2021 Nov; 9(11): e1816. Published online 2021 Oct 11. doi: 10.1002/mgg3.1816

PMCID:: PMC8606218

Abstract Article PDF–781K

Select item 842045617.

Targeting neuropilins as a viable SARS‐CoV‐2 treatment

Sarvenaz Sarabipour, Feilim Mac Gabhann

FEBS J. 2021 Sep; 288(17): 5122–5129. Published online 2021 Jul 12. doi: 10.1111/febs.16096

PMCID:: PMC8420456

Abstract Article PDF–2.4M

Select item 816503018.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 807338919.

The Role of Heparan Sulfate and Neuropilin 2 in VEGFA Signaling in Human Endothelial Tip Cells and Non-Tip Cells during Angiogenesis In Vitro

Marchien G. Dallinga, Yasmin I. Habani, Alinda W. M. Schimmel, Geesje M. Dallinga-Thie, Cornelis J. F. van Noorden, Ingeborg Klaassen, Reinier O. Schlingemann

Cells. 2021 Apr; 10(4): 926. Published online 2021 Apr 16. doi: 10.3390/cells10040926

PMCID:: PMC8073389

Abstract Article PDF–3.2M

Select item 807036820.

Neuropilin-2 and Its Transcript Variants Correlate with Clinical Outcome in Bladder Cancer

Sarah Förster, Maryam Givehchi, Katja Nitschke, Thomas Mayr, Kerstin Kilian, Samikshan Dutta, Kaustubh Datta, Philipp Nuhn, Zoran Popovic, Michael H. Muders, Philipp Erben

Genes (Basel) 2021 Apr; 12(4): 550. Published online 2021 Apr 9. doi: 10.3390/genes12040550

PMCID:: PMC8070368

Abstract Article PDF–3.0M

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