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Select item 105289541.

Induction of Glucose Production by Heterocyclic Amines is Dependent on N-acetyltransferase 2 Genetic Polymorphism in Cryopreserved Human Hepatocytes

Kennedy M. Walls, Kyung U. Hong, David W. Hein

Toxicol Lett. Author manuscript; available in PMC 2024 Jul 7.

Published in final edited form as: Toxicol Lett. 2023 Jul 1; 383: 192–195. Published online 2023 Jul 7. doi: 10.1016/j.toxlet.2023.07.002

PMCID:: PMC10528954

Abstract Article PDF–409K

Select item 105247192.

N-Acetyltransferase 2 Haplotype Modifies Risks for Both Dyslipidemia and Urinary Bladder Cancer

Kyung U. Hong, David W. Hein

Pharmacogenet Genomics. Author manuscript; available in PMC 2024 Aug 1.

Published in final edited form as: Pharmacogenet Genomics. 2023 Aug 1; 33(6): 136–137. Published online 2023 May 29. doi: 10.1097/FPC.0000000000000500

PMCID:: PMC10524719

Abstract Article PDF–293K

Select item 103614693.

The impact of IDH and NAT2 gene polymorphisms in acute myeloid leukemia risk and overall survival in an Arab population: A case-control study

Sohaib M. Al-Khatib, Obada Ababneh, Hassann Abushukair, Nour Abdo, Laith N. Al-Eitan

PLoS One. 2023; 18(7): e0289014. Published online 2023 Jul 21. doi: 10.1371/journal.pone.0289014

PMCID:: PMC10361469

Abstract Article PDF–988K

Select item 101878824.

N-acetyltransferase 2 genetic polymorphism modifies genotoxic and oxidative damage from new psychoactive substances

Raúl A. Salazar-González, Mark A. Doll, David W Hein

Arch Toxicol. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: Arch Toxicol. 2023 Jan; 97(1): 189–199. Published online 2022 Sep 23. doi: 10.1007/s00204-022-03383-2

PMCID:: PMC10187882

Abstract Article PDF–956K

Select item 100790695.

NAT2 global landscape: Genetic diversity and acetylation statuses from a systematic review

Jorge E. Gutiérrez-Virgen, Maricela Piña-Pozas, Esther A. Hernández-Tobías, Lucia Taja-Chayeb, Ma. de Lourdes López-González, Marco A. Meraz-Ríos, Rocío Gómez

PLoS One. 2023; 18(4): e0283726. Published online 2023 Apr 6. doi: 10.1371/journal.pone.0283726

PMCID:: PMC10079069

Abstract Article PDF–2.5M

Select item 98843976.

Pharmacogenetic testing for NAT2 genotypes in a Tanzanian population across the lifespan to guide future personalized isoniazid dosing

Maano V. Masiphephethu, Margaretha Sariko, Thomas Walongo, Athanasia Maro, Dorcus Mduma, Jean Gratz, Mohammad Alshaer, Charles A. Peloquin, Estomih Mduma, Stellah G. Mpagama, Tania Thomas, Eric R. Houpt, Afsatou Traore, Pascal Bessong, Scott K. Heysell, Darwin J. Operario

Tuberculosis (Edinb) Author manuscript; available in PMC 2023 Jan 29.

Published in final edited form as: Tuberculosis (Edinb). 2022 Sep; 136: 102246. Published online 2022 Aug 8. doi: 10.1016/j.tube.2022.102246

PMCID:: PMC9884397

Abstract Article PDF–864K

Select item 97029987.

Transcriptional Regulation of Human Arylamine N-Acetyltransferase 2 Gene by Glucose and Insulin in Liver Cancer Cell Lines

Kyung U Hong, Raúl A Salazar-González, Kennedy M Walls, David W Hein

Toxicol Sci. 2022 Dec; 190(2): 158–172. Published online 2022 Sep 26. doi: 10.1093/toxsci/kfac103

PMCID:: PMC9702998

Abstract Article PDF–922K

Select item 95224188.

Influence of NAT2 Genotype and Maturation on Isoniazid Exposure in Low-Birth-Weight and Preterm Infants With or Without Human Immunodeficiency Virus (HIV) Exposure

Agathe Béranger, Adrie Bekker, Belén P Solans, Mark F Cotton, Mark Mirochnick, Avy Violari, Jiajia Wang, Mae Cababasay, Lubbe Wiesner, Renee Browning, Jack Moye, Edmund V Capparelli, Radojka M Savic

Clin Infect Dis. 2022 Sep 15; 75(6): 1037–1045. Published online 2022 Feb 4. doi: 10.1093/cid/ciac001

PMCID:: PMC9522418

Abstract Article PDF–8.5M

Select item 93565569.

NAT2 and CYP2E1 polymorphisms and antituberculosis drug‐induced hepatotoxicity in Peruvian patients

Luis Jaramillo‐Valverde, Kelly S. Levano, David D. Tarazona, Silvia Capristano, Roberto Zegarra‐Chapoñan, Cesar Sanchez, Velia M. Yufra‐Picardo, Eduardo Tarazona‐Santos, Cesar Ugarte‐Gil, Heinner Guio

Mol Genet Genomic Med. 2022 Aug; 10(8): e1987. Published online 2022 Jun 24. doi: 10.1002/mgg3.1987

PMCID:: PMC9356556

Abstract Article PDF–685K

Select item 911207610.

Expression of Arylamine N-Acetyltransferase 2 Activity in Immortalized Human Bronchial Epithelial Cells

James T.F. Wise, Raúl A. Salazar-González, Mariam R. Habil, Mark A. Doll, David W. Hein

Toxicol Appl Pharmacol. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: Toxicol Appl Pharmacol. 2022 May 1; 442: 115993. Published online 2022 Mar 27. doi: 10.1016/j.taap.2022.115993

PMCID:: PMC9112076

Abstract Article PDF–1.3M

Select item 862945911.

Modifying Effect of Smoking on GSTM1 and NAT2 in Relation to the Risk of Bladder Cancer in Mongolian Population: A Case-Control Study

Shiirevnyamba Avirmed, Yerkhanat Khuanbai, Amarsaikhan Sanjaajamts, Baasansuren Selenge, Bayan-Undur Dagvadorj, Makoto Ohashi

Asian Pac J Cancer Prev. 2021 Aug; 22(8): 2479–2485. doi: 10.31557/APJCP.2021.22.8.2479

PMCID:: PMC8629459

Abstract Article PDF–302K

Select item 858010112.

Allelic and genotypic frequencies of NAT2, CYP2E1, and AADAC genes in a cohort of Peruvian tuberculosis patients

Kelly S. Levano, Luis Jaramillo‐Valverde, David D. Tarazona, Cesar Sanchez, Silvia Capristano, Tania Vásquez‐Loarte, Lely Solari, Alberto Mendoza‐Ticona, Alonso Soto, Christian Rojas, Roberto Zegarra‐Chapoñan, Heinner Guio

Mol Genet Genomic Med. 2021 Oct; 9(10): e1764. Published online 2021 Sep 12. doi: 10.1002/mgg3.1764

PMCID:: PMC8580101

Abstract Article PDF–552K

Select item 816503013.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 804631514.

Evaluation of Genetic Polymorphisms of N-acetyltransferase 2 and Relation with Chronic Myeloid Leukemia

Entesar M Tebien, Hiba B Khalil, Jeremy Mills, Abozer Y. Elderdery

Asian Pac J Cancer Prev. 2020 Dec; 21(12): 3711–3717. doi: 10.31557/APJCP.2020.21.12.3711

PMCID:: PMC8046315

Abstract Article PDF–397K

Select item 749701815.

Unexpected Acetylation of Endogenous Aliphatic Amines by Arylamine N‐Acetyltransferase NAT2

Dr. Louis P. Conway, Dr. Veronica Rendo, M. Sc. Mário S. P. Correia, Prof. Dr. Ingvar A. Bergdahl, Prof. Dr. Tobias Sjöblom, Prof. Dr. Daniel Globisch

Angew Chem Int Ed Engl. 2020 Aug 17; 59(34): 14342–14346. Published online 2020 Jul 8. doi: 10.1002/anie.202005915

PMCID:: PMC7497018

Abstract Article PDF–2.0M

Select item 716998316.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x