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Items: 1 to 20 of 112

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Modulation of cAMP/cGMP signaling as prevention of congenital heart defects in Pde2A deficient embryos: a matter of oxidative stress
Silvia Cardarelli, Martina Biglietto, Tiziana Orsini, Valentina Fustaino, Lucia Monaco, Ana Gabriela de Oliveira do Rêgo, Francesca Liccardo, Silvia Masciarelli, Francesco Fazi, Fabio Naro, Luciana De Angelis, Manuela Pellegrini
Cell Death Dis. 2024 Feb; 15(2): 169. Published online 2024 Feb 23. doi: 10.1038/s41419-024-06549-1
PMCID:
PMC10891154
AbstractArticlePDF–2.6M
3.
miR-195b is required for proper cellular homeostasis in the elderly
Maria del Mar Muñoz-Gallardo, Carlos Garcia-Padilla, Cristina Vicente-Garcia, Jaime Carvajal, Amelia Arenega, Diego Franco
Sci Rep. 2024; 14: 810. Published online 2024 Jan 8. doi: 10.1038/s41598-024-51256-8
PMCID:
PMC10774362
AbstractArticlePDF–3.7M
4.
ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment
Jiawen Xiang, Anthony J. Pompetti, Adam P. Faranda, Yan Wang, Samuel G. Novo, David Wan-Cheng Li, Melinda K. Duncan
Cells. 2023 Nov; 12(22): 2636. Published online 2023 Nov 16. doi: 10.3390/cells12222636
PMCID:
PMC10670291
AbstractArticlePDF–9.2M
5.
The placental vasculature is affected by changes in gene expression and glycogen-rich cells in a diet-induced obesity mouse model
Hui Zhao, Ronald J. Wong, David K. Stevenson
PLoS One. 2023; 18(11): e0294185. Published online 2023 Nov 10. doi: 10.1371/journal.pone.0294185
PMCID:
PMC10637699
AbstractArticlePDF–3.6M
6.
Hacd2 deficiency in mice leads to an early and lethal mitochondrial disease
Nahed Khadhraoui, Alexandre Prola, Aymeline Vandestienne, Jordan Blondelle, Laurent Guillaud, Guillaume Courtin, Maxime Bodak, Bastien Prost, Hélène Huet, Mélody Wintrebert, Christine Péchoux, Audrey Solgadi, Frédéric Relaix, Laurent Tiret, Fanny Pilot-Storck
Mol Metab. 2023 Mar; 69: 101677. Published online 2023 Jan 21. doi: 10.1016/j.molmet.2023.101677
PMCID:
PMC9986742
AbstractArticlePDF–3.1M
7.
The role of selenoproteins in neutrophils during inflammation
Tai-Jung Lee, Shaneice K. Nettleford, Allison McGlynn, Bradley A. Carlson, Girish S. Kirimanjeswara, K. Sandeep Prabhu
Arch Biochem Biophys. Author manuscript; available in PMC 2023 Dec 15.
Published in final edited form as: Arch Biochem Biophys. 2022 Dec 15; 732: 109452. Published online 2022 Nov 3. doi: 10.1016/j.abb.2022.109452
PMCID:
PMC9712253
AbstractArticlePDF–821K
8.
Role and mechanism of REG2 depletion in insulin secretion augmented by glutathione peroxidase-1 overproduction
Xi Yan, Zeping Zhao, Jeremy Weaver, Tao Sun, Jun-Won Yun, Carol A. Roneker, Fenghua Hu, Nicolai M. Doliba, Charles Chipley W. McCormick, Marko Z. Vatamaniuk, Xin Gen Lei
Redox Biol. 2022 Oct; 56: 102457. Published online 2022 Aug 30. doi: 10.1016/j.redox.2022.102457
PMCID:
PMC9463454
AbstractArticlePDF–4.6M
9.
Glutathione Peroxidase 1 Protects Against Peroxynitrite-Induced Spiral Ganglion Neuron Damage Through Attenuating NF-κB Pathway Activation
Xue Wang, Yuechen Han, Fang Chen, Man Wang, Yun Xiao, Haibo Wang, Lei Xu, Wenwen Liu
Front Cell Neurosci. 2022; 16: 841731. Published online 2022 Mar 23. doi: 10.3389/fncel.2022.841731
PMCID:
PMC8983938
AbstractArticlePDF–8.5M
10.
Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance
Chrysovalantou E. Xirouchaki, Yaoyao Jia, Meagan J. McGrath, Spencer Greatorex, Melanie Tran, Troy L. Merry, Dawn Hong, Matthew J. Eramo, Sophie C. Broome, Jonathan S. T. Woodhead, Randall F. D’souza, Jenny Gallagher, Ekaterina Salimova, Cheng Huang, Ralf B. Schittenhelm, Junichi Sadoshima, Matthew J. Watt, Christina A. Mitchell, Tony Tiganis
Sci Adv. 2021 Dec; 7(51): eabl4988. Published online 2021 Dec 15. doi: 10.1126/sciadv.abl4988
PMCID:
PMC8673768
AbstractArticlePDF–3.2M
11.
CCL5 via GPX1 activation protects hippocampal memory function after mild traumatic brain injury
Man-Hau Ho, Chia-Hung Yen, Tsung-Hsun Hsieh, Tzu-Jen Kao, Jing-Yuan Chiu, Yung-Hsiao Chiang, Barry J. Hoffer, Wen-Chang Chang, Szu-Yi Chou
Redox Biol. 2021 Oct; 46: 102067. Published online 2021 Jul 17. doi: 10.1016/j.redox.2021.102067
PMCID:
PMC8327355
AbstractArticlePDF–13M
12.
Glutathione peroxidase-1 regulates ASK1-dependent apoptosis via interaction with TRAF2 in RIPK3-negative cancer cells
Sunmi Lee, Eun-Kyung Lee, Dong Hoon Kang, Jiyoung Lee, Soo Hyun Hong, Woojin Jeong, Sang Won Kang
Exp Mol Med. 2021 Jun; 53(6): 1080–1091. Published online 2021 Jun 22. doi: 10.1038/s12276-021-00642-7
PMCID:
PMC8257591
AbstractArticlePDF–3.1M
13.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
14.
Dysregulation of hypoxia-inducible factor-1α (Hif1α) expression in the Hmox1-deficient placenta
Hui Zhao, Purnima Narasimhan, Flora Kalish, Ronald J. Wong, David K. Stevenson
Placenta. 2020 Sep 15; 99: 108–116. doi: 10.1016/j.placenta.2020.07.015
PMCID:
PMC7549641
AbstractArticle
15.
PER1 interaction with GPX1 regulates metabolic homeostasis under oxidative stress
Qi Sun, Yunxia Yang, Zhongqiu Wang, Xiao Yang, Yan Gao, Yang Zhao, Wenhao Ge, Junhao Liu, Xi Xu, Wei Guan, Dan Weng, Shiming Wang, Junsong Wang, Jianfa Zhang
Redox Biol. 2020 Oct; 37: 101694. Published online 2020 Aug 26. doi: 10.1016/j.redox.2020.101694
PMCID:
PMC7484554
AbstractArticlePDF–11M
16.
Glutathione peroxidase‐1 overexpression reduces oxidative stress, and improves pathology and proteome remodeling in the kidneys of old mice
Yi Chu, Renny S. Lan, Rui Huang, Hao Feng, Rahul Kumar, Sanjana Dayal, Kung‐Sik Chan, Dao‐Fu Dai
Aging Cell. 2020 Jun; 19(6): e13154. Published online 2020 May 13. doi: 10.1111/acel.13154
PMCID:
PMC7294784
AbstractArticlePDF–2.3M
17.
Mild depolarization of the inner mitochondrial membrane is a crucial component of an anti-aging program
Mikhail Y. Vyssokikh, Susanne Holtze, Olga A. Averina, Konstantin G. Lyamzaev, Alisa A. Panteleeva, Maria V. Marey, Roman A. Zinovkin, Fedor F. Severin, Maxim V. Skulachev, Nicolas Fasel, Thomas B. Hildebrandt, Vladimir P. Skulachev
Proc Natl Acad Sci U S A. 2020 Mar 24; 117(12): 6491–6501. Published online 2020 Mar 9. doi: 10.1073/pnas.1916414117
PMCID:
PMC7104298
AbstractArticlePDF–1.8M
18.
Lens aquaporins function as peroxiporins to facilitate membrane transport of hydrogen peroxide
Kulandaiappan Varadaraj, S. Sindhu Kumari
Biochem Biophys Res Commun. Author manuscript; available in PMC 2021 Apr 16.
Published in final edited form as: Biochem Biophys Res Commun. 2020 Apr 16; 524(4): 1025–1029. Published online 2020 Feb 13. doi: 10.1016/j.bbrc.2020.02.031
PMCID:
PMC7085977
AbstractArticlePDF–1008K
19.
Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers
Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang
FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R
PMCID:
PMC6993925
AbstractArticle
20.
Mice Deficient in Cellular Glutathione Peroxidase Show Increased Vulnerability to Malonate, 3-Nitropropionic Acid, and 1-Methyl-4-Phenyl-1,2,5,6-Tetrahydropyridine
Peter Klivenyi, Ole A. Andreassen, Robert J. Ferrante, Alpaslan Dedeoglu, Gerald Mueller, Eric Lancelot, Mikhail Bogdanov, Julie K. Andersen, Dongmei Jiang, M. Flint Beal
J Neurosci. 2000 Jan 1; 20(1): 1–7. doi: 10.1523/JNEUROSCI.20-01-00001.2000
PMCID:
PMC6774090
AbstractArticlePDF–261K

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