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Select item 114767581.

Epidermal RORα Maintains Barrier Integrity and Prevents Allergic Inflammation by Regulating Late Differentiation and Lipid Metabolism

Xiangmei Hua, Maria K. Ficaro, Nicole L. Wallace, Jun Dai

Int J Mol Sci. 2024 Oct; 25(19): 10698. Published online 2024 Oct 4. doi: 10.3390/ijms251910698

PMCID:: PMC11476758

Abstract Article PDF–3.8M

Select item 113440802.

Prefrontal cortex molecular clock modulates development of depression-like phenotype and rapid antidepressant response in mice

David H. Sarrazin, Wilf Gardner, Carole Marchese, Martin Balzinger, Chockalingam Ramanathan, Marion Schott, Stanislav Rozov, Maxime Veleanu, Stefan Vestring, Claus Normann, Tomi Rantamäki, Benedicte Antoine, Michel Barrot, Etienne Challet, Patrice Bourgin, Tsvetan Serchov

Nat Commun. 2024; 15: 7257. Published online 2024 Aug 23. doi: 10.1038/s41467-024-51716-9

PMCID:: PMC11344080

Abstract Article PDF–4.4M

Select item 109952643.

RORα–GABP–TFAM axis alleviates myosteatosis with fatty atrophy through reinforcement of mitochondrial capacity

Hyeon‐Ji Kim, Sang‐Heon Lee, Cheolhee Jeong, Yong‐Hyun Han, Mi‐Ock Lee

J Cachexia Sarcopenia Muscle. 2024 Apr; 15(2): 615–630. Published online 2024 Jan 25. doi: 10.1002/jcsm.13432

PMCID:: PMC10995264

Abstract Article PDF–5.2M

Select item 109176604.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108796995.

Neuronal reprogramming of mouse and human fibroblasts using transcription factors involved in suprachiasmatic nucleus development

Masatoshi Hirayama, Ludovic S. Mure, Hiep D. Le, Satchidananda Panda

iScience. 2024 Mar 15; 27(3): 109051. Published online 2024 Jan 30. doi: 10.1016/j.isci.2024.109051

PMCID:: PMC10879699

Abstract Article PDF–5.2M

Select item 105807026.

RORα overexpression reduced interleukin‐33 expression and prevented mast cell degranulation and inflammation by inducing autophagy in allergic rhinitis

Wangbo Yu, Jingwei Du, Lijuan Peng, Tao Zhang

Immun Inflamm Dis. 2023 Oct; 11(10): e1017. Published online 2023 Oct 17. doi: 10.1002/iid3.1017

PMCID:: PMC10580702

Abstract Article PDF–5.6M

Select item 104048167.

Retinoic Acid–Related Orphan Receptor α Is Required for Generation of Th2 Cells in Type 2 Pulmonary Inflammation

Joseph Roberts, Anne Chevalier, Heike C. Hawerkamp, Aoife Yeow, Laura Matarazzo, Christian Schwartz, Emily Hams, Padraic G. Fallon

J Immunol. 2023 Aug 15; 211(4): 626–632. Published online 2023 Jun 30. doi: 10.4049/jimmunol.2200896

PMCID:: PMC10404816

Abstract Article PDF–1.3M

Select item 103781918.

Phospholipid scramblase-1 regulates innate type 2 inflammation in mouse lungs via CRTH2-dependent mechanisms

Ashley Hernandez-Gutierrez, Sonoor Majid, Adam Eberle, Ashley Choi, Parand Sorkhdini, Dongqin Yang, Alina Xiaoyu Yang, Carmelissa Norbrun, Chuan Hua He, Chang-min Lee, Chun Geun Lee, Jack A. Elias, Yang Zhou

J Clin Invest. 2023 Aug 1; 133(15): e169583. Published online 2023 Aug 1. doi: 10.1172/JCI169583

PMCID:: PMC10378191

Abstract Article PDF–7.3M

Select item 102989189.

Epidermal Loss of RORα Enhances Skin Inflammation in a MC903-Induced Mouse Model of Atopic Dermatitis

Xiangmei Hua, Conrad Dean Blosch, Hannah Dorsey, Maria K. Ficaro, Nicole L. Wallace, Richard P. Hsung, Jun Dai

Int J Mol Sci. 2023 Jun; 24(12): 10241. Published online 2023 Jun 16. doi: 10.3390/ijms241210241

PMCID:: PMC10298918

Abstract Article PDF–6.0M

Select item 997447410.

The circadian demethylation of a unique intronic deoxymethylCpG-rich island boosts the transcription of its cognate circadian clock output gene

Nisha Misra, Manohar Damara, Tao Ye, Pierre Chambon

Proc Natl Acad Sci U S A. 2023 Feb 21; 120(8): e2214062120. Published online 2023 Feb 15. doi: 10.1073/pnas.2214062120

PMCID:: PMC9974474

Abstract Article PDF–1.1M

Select item 989416511.

Transcriptional control of cone photoreceptor diversity by a thyroid hormone receptor

Michihiko Aramaki, Xuefeng Wu, Hong Liu, Ye Liu, Young-Wook Cho, Mina Song, Yulong Fu, Lily Ng, Douglas Forrest

Proc Natl Acad Sci U S A. 2022 Dec 6; 119(49): e2209884119. Published online 2022 Dec 1. doi: 10.1073/pnas.2209884119

PMCID:: PMC9894165

Abstract Article PDF–2.6M

Select item 988059712.

Developmental trajectories of thalamic progenitors revealed by single-cell transcriptome profiling and Shh perturbation

Kiya W. Govek, Sixing Chen, Paraskevi Sgourdou, Yao Yao, Steven Woodhouse, Tingfang Chen, Marc V. Fuccillo, Douglas J. Epstein, Pablo G. Camara

Cell Rep. Author manuscript; available in PMC 2023 Jan 27.

Published in final edited form as: Cell Rep. 2022 Dec 6; 41(10): 111768. doi: 10.1016/j.celrep.2022.111768

PMCID:: PMC9880597

Abstract Article PDF–2.4M

Select item 987663313.

Genetic deficiency and pharmacological modulation of RORα regulate laser-induced choroidal neovascularization

Chi-Hsiu Liu, Felix Yemanyi, Kiran Bora, Neetu Kushwah, Alexandra K. Blomfield, Theodore M. Kamenecka, John Paul SanGiovanni, Ye Sun, Laura A. Solt, Jing Chen

Aging (Albany NY) 2023 Jan 15; 15(1): 37–52. Published online 2023 Jan 10. doi: 10.18632/aging.204480

PMCID:: PMC9876633

Abstract Article PDF–1.4M

Select item 986776114.

Wdr4 promotes cerebellar development and locomotion through Arhgap17-mediated Rac1 activation

Pei-Rung Wu, Shang-Yin Chiang, Robert Midence, Wen-Chao Kao, Chun-Lun Lai, I-Cheng Cheng, Shen-Ju Chou, Chih-Cheng Chen, Chih-Yang Huang, Ruey-Hwa Chen

Cell Death Dis. 2023 Jan; 14(1): 52. Published online 2023 Jan 21. doi: 10.1038/s41419-022-05442-z

PMCID:: PMC9867761

Abstract Article PDF–10M

Select item 975708115.

Transcription factor RORα enforces stability of the Th17 cell effector program by binding to a Rorc cis-regulatory element

Jason A. Hall, Maria Pokrovskii, Lina Kroehling, Bo-Ram Kim, Seung Yong Kim, Lin Wu, June-Yong Lee, Dan R. Littman

Immunity. Author manuscript; available in PMC 2022 Dec 16.

Published in final edited form as: Immunity. 2022 Nov 8; 55(11): 2027–2043.e9. Published online 2022 Oct 14. doi: 10.1016/j.immuni.2022.09.013

PMCID:: PMC9757081

Abstract Article PDF–3.2M

Select item 960586516.

Novel antigen-presenting cell imparts T_reg-dependent tolerance to gut microbiota

Blossom Akagbosu, Zakieh Tayyebi, Gayathri Shibu, Yoselin A. Paucar Iza, Deeksha Deep, Yollanda Franco Parisotto, Logan Fisher, H. Amalia Pasolli, Valentin Thevin, Rasa Elmentaite, Maximilian Knott, Saskia Hemmers, Lorenz Jahn, Christin Friedrich, Jacob Verter, Zhong-Min Wang, Marcel van den Brink, Georg Gasteiger, Thomas G. P. Grünewald, Julien C. Marie, Christina Leslie, Alexander Y. Rudensky, Chrysothemis C. Brown

Nature. 2022; 610(7933): 752–760. Published online 2022 Sep 7. doi: 10.1038/s41586-022-05309-5

PMCID:: PMC9605865

Abstract Article PDF–14M

Select item 934325317.

Temporally divergent regulatory mechanisms govern neuronal diversification and maturation in the mouse and marmoset neocortex

Wen Yuan, Sai Ma, Juliana R. Brown, Kwanho Kim, Vanessa Murek, Lucia Trastulla, Alexander Meissner, Simona Lodato, Ashwin S. Shetty, Joshua Z. Levin, Jason D. Buenrostro, Michael J. Ziller, Paola Arlotta

Nat Neurosci. 2022; 25(8): 1049–1058. Published online 2022 Aug 1. doi: 10.1038/s41593-022-01123-4

PMCID:: PMC9343253

Abstract Article PDF–17M

Select item 929575418.

Thalamocortical axons regulate neurogenesis and laminar fates in the early sensory cortex

Timothy Monko, Jaclyn Rebertus, Jeff Stolley, Stephen R. Salton, Yasushi Nakagawa

Proc Natl Acad Sci U S A. 2022 May 31; 119(22): e2201355119. Published online 2022 May 25. doi: 10.1073/pnas.2201355119

PMCID:: PMC9295754

Abstract Article PDF–3.8M

Select item 899045919.

The suppressive functions of Rora in B lineage cell proliferation and BCR/ABL1-induced B-ALL pathogenesis

Ning Li, Nan Wang, Wei He, Yunyu Feng, Qiang Qiu, Huandi Qiu, Li Zheng, Yuexia Yin, Bochuan Wang, Yuanyuan Sun, Cong Pan, Klarke M. Sample, Juan Huang, Zhiguang Su, Zhihui Li, Haojian Zhang, Yiguo Hu

Int J Biol Sci. 2022; 18(6): 2277–2291. Published online 2022 Mar 6. doi: 10.7150/ijbs.68939

PMCID:: PMC8990459

Abstract Article PDF–3.4M

Select item 895960420.

Thalamocortical axons control the cytoarchitecture of neocortical layers by area-specific supply of VGF

Haruka Sato, Jun Hatakeyama, Takuji Iwasato, Kimi Araki, Nobuhiko Yamamoto, Kenji Shimamura

eLife. 2022; 11: e67549. Published online 2022 Mar 15. doi: 10.7554/eLife.67549

PMCID:: PMC8959604

Abstract Article PDF–6.6M

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