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Items: 1 to 20 of 34

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Spontaneous allelic variant in deafness–blindness gene Ush1g resulting in an expanded phenotype
Vladimir Vartanian, Jocelyn F. Krey, Paroma Chatterjee, Allison Curtis, Makayla Six, Sean P. M. Rice, Sherri M. Jones, Harini Sampath, Charles N. Allen, Renee C. Ryals, R. Stephen Lloyd, Peter G. Barr‐Gillespie
Genes Brain Behav. 2023 Aug; 22(4): e12849. Published online 2023 Jun 16. doi: 10.1111/gbb.12849
PMCID:
PMC10393423
AbstractArticlePDF–5.0M
3.
NEIL1 and NEIL2 DNA glycosylases modulate anxiety and learning in a cooperative manner in mice
Gunn A. Hildrestrand, Veslemøy Rolseth, Nicolas Kunath, Rajikala Suganthan, Vidar Jensen, Anna M. Bugaj, Marion S. Fernandez-Berrocal, Sunniva B. Sikko, Susanne Vetlesen, Anna Kuśnierczyk, Ann-Karin Olsen, Kristine B. Gützkow, Alexander D. Rowe, Wei Wang, Olve Moldestad, Monica D. Syrstad, Geir Slupphaug, Lars Eide, Arne Klungland, Pål Sætrom, Luisa Luna, Jing Ye, Katja Scheffler, Magnar Bjørås
Commun Biol. 2021; 4: 1354. Published online 2021 Dec 2. doi: 10.1038/s42003-021-02864-x
PMCID:
PMC8639745
AbstractArticlePDF–4.6M
4.
DNA Glycosylase Deficiency Leads to Decreased Severity of Lupus in the Polb-Y265C Mouse Model
Sesha L. Paluri, Matthew Burak, Alireza G. Senejani, Madison Levinson, Tania Rahim, Kaylyn Clairmont, Michael Kashgarian, Isabel Alvarado-Cruz, Rithy Meas, Marina Cardó-Vila, Caroline Zeiss, Stephen Maher, Alfred L.M. Bothwell, Erdem Coskun, Melis Kant, Pawel Jaruga, Miral Dizdaroglu, R. Stephen Lloyd, Joann B. Sweasy
DNA Repair (Amst) Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: DNA Repair (Amst). 2021 Sep; 105: 103152. Published online 2021 Jun 24. doi: 10.1016/j.dnarep.2021.103152
PMCID:
PMC8635285
AbstractArticlePDF–1.5M
5.
Enzymatic Hydroxylation and Excision of Extended 5-Methylcytosine Analogues
Miglė Tomkuvienė, Diana Ikasalaitė, Anton Slyvka, Audronė Rukšėnaitė, Mirunalini Ravichandran, Tomasz P. Jurkowski, Matthias Bochtler, Saulius Klimašauskas
J Mol Biol. 2020 Nov 20; 432(23): 6157–6167. doi: 10.1016/j.jmb.2020.10.011
PMCID:
PMC7763475
AbstractArticle
6.
NEIL1 stimulates neurogenesis and suppresses neuroinflammation after stress
Beimeng Yang, David M. Figueroa, Yujun Hou, Mansi Babbar, Stephanie L. Baringer, Deborah L. Croteau, Vilhelm A. Bohr
Free Radic Biol Med. Author manuscript; available in PMC 2020 Sep 30.
Published in final edited form as: Free Radic Biol Med. 2019 Sep; 141: 47–58. Published online 2019 Jun 5. doi: 10.1016/j.freeradbiomed.2019.05.037
PMCID:
PMC7526462
AbstractArticlePDF–2.3M
7.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
8.
NEIL1 and NEIL2 DNA glycosylases protect neural crest development against mitochondrial oxidative stress
Dandan Han, Lars Schomacher, Katrin M Schüle, Medhavi Mallick, Michael U Musheev, Emil Karaulanov, Laura Krebs, Annika von Seggern, Christof Niehrs
eLife. 2019; 8: e49044. Published online 2019 Sep 30. doi: 10.7554/eLife.49044
PMCID:
PMC6768664
AbstractArticlePDF–7.2M
9.
Loss of endonuclease eight-like 1 causes defects in olfactory function in mice
Chandrika Canugovi, Magdalena Misiak, Morten Scheibye-Knudsen, Deborah L. Croteau, Mark P. Mattson, Vilhelm A. Bohr
Neurobiol Aging. Author manuscript; available in PMC 2017 Aug 30.
Published in final edited form as: Neurobiol Aging. 2015 Feb; 36(2): 1007–1012. Published online 2014 Oct 14. doi: 10.1016/j.neurobiolaging.2014.09.026
PMCID:
PMC5576891
AbstractArticlePDF–673K
10.
Enhanced Sensitivity of Neil1−/− Mice to Chronic UVB Exposure
Marcus J Calkins, Vladimir Vartanian, Nichole Owen, Guldal Kirkali, Pawel Jaruga, Miral Dizdaroglu, Amanda K. McCullough, Stephen R. Lloyd
DNA Repair (Amst) Author manuscript; available in PMC 2017 Dec 1.
Published in final edited form as: DNA Repair (Amst). 2016 Dec; 48: 43–50. Published online 2016 Oct 28. doi: 10.1016/j.dnarep.2016.10.010
PMCID:
PMC5499380
AbstractArticlePDF–1.2M
11.
No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice
Veslemøy Rolseth, Luisa Luna, Ann Karin Olsen, Rajikala Suganthan, Katja Scheffler, Christine G. Neurauter, Ying Esbensen, Anna Kuśnierczyk, Gunn A. Hildrestrand, Anne Graupner, Jill M. Andersen, Geir Slupphaug, Arne Klungland, Hilde Nilsen, Magnar Bjørås
Sci Rep. 2017; 7: 4384. Published online 2017 Jun 29. doi: 10.1038/s41598-017-04472-4
PMCID:
PMC5491499
AbstractArticlePDF–1.9M
12.
NEIL1 protects against aflatoxin-induced hepatocellular carcinoma in mice
Vladimir Vartanian, Irina G. Minko, Supawadee Chawanthayatham, Patricia A. Egner, Ying-Chih Lin, Lauriel F. Earley, Rosemary Makar, Jennifer R. Eng, Matthew T. Camp, Liang Li, Michael P. Stone, Michael R. Lasarev, John D. Groopman, Robert G. Croy, John M. Essigmann, Amanda K. McCullough, R. Stephen Lloyd
Proc Natl Acad Sci U S A. 2017 Apr 18; 114(16): 4207–4212. Published online 2017 Apr 3. doi: 10.1073/pnas.1620932114
PMCID:
PMC5402411
AbstractArticlePDF–1.4M
13.
Deficiency of the oxidative damage-specific DNA glycosylase NEIL1 leads to reduced germinal center B cell expansion
Hiromi Mori, Rika Ouchida, Atsushi Hijikata, Hiroshi Kitamura, Osamu Ohara, Yingqian Li, Xiang Gao, Akira Yasui, R. Stephen Lloyd, Ji-Yang Wang
DNA Repair (Amst) Author manuscript; available in PMC 2016 Jun 21.
Published in final edited form as: DNA Repair (Amst). 2009 Nov 2; 8(11): 1328–1332. Published online 2009 Sep 24. doi: 10.1016/j.dnarep.2009.08.007
PMCID:
PMC4915481
AbstractArticlePDF–1.9M
14.
Targeted deletion of the genes encoding NTH1 and NEIL1 DNA N-glycosylases reveals the existence of novel carcinogenic oxidative damage to DNA
Michael K. Chan, Maria T. Ocampo-Hafalla, Vladimir Vartanian, Pawel Jaruga, Güldal Kirkali, Karen L. Koenig, Stuart Brown, R. Stephen Lloyd, Miral Dizdaroglu, George W. Teebor
DNA Repair (Amst) Author manuscript; available in PMC 2016 Jun 6.
Published in final edited form as: DNA Repair (Amst). 2009 Jul 4; 8(7): 786–794. Published online 2009 Apr 5. doi: 10.1016/j.dnarep.2009.03.001
PMCID:
PMC4894318
AbstractArticlePDF–937K
15.
Regulation of NEIL1 protein abundance by RAD9 is important for efficient base excision repair
Sunil K. Panigrahi, Kevin M. Hopkins, Howard B. Lieberman
Nucleic Acids Res. 2015 May 19; 43(9): 4531–4546. Published online 2015 Apr 14. doi: 10.1093/nar/gkv327
PMCID:
PMC4482081
AbstractArticlePDF–5.2M
16.
Hypersensitivity of mouse NEIL1-knockdown cells to hydrogen peroxide during S phase
Ryohei Yamamoto, Yukari Ohshiro, Tatsuhiko Shimotani, Mizuki Yamamoto, Satoshi Matsuyama, Hiroshi Ide, Kihei Kubo
J Radiat Res. 2014 Jul; 55(4): 707–712. Published online 2014 Apr 4. doi: 10.1093/jrr/rru021
PMCID:
PMC4100011
AbstractArticlePDF–277K
17.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
18.
Neil3 and NEIL1 DNA Glycosylases Remove Oxidative Damages from Quadruplex DNA and Exhibit Preferences for Lesions in the Telomeric Sequence Context
Jia Zhou, Minmin Liu, Aaron M. Fleming, Cynthia J. Burrows, Susan S. Wallace
J Biol Chem. 2013 Sep 20; 288(38): 27263–27272. Published online 2013 Aug 7. doi: 10.1074/jbc.M113.479055
PMCID:
PMC3779722
AbstractArticlePDF–1.3M
19.
Neil1 is a genetic modifier of somatic and germline CAG trinucleotide repeat instability in R6/1 mice
Linda Møllersen, Alexander D. Rowe, Jennifer L. Illuzzi, Gunn A. Hildrestrand, Katharina J. Gerhold, Linda Tveterås, Anja Bjølgerud, David M. Wilson, III, Magnar Bjørås, Arne Klungland
Hum Mol Genet. 2012 Nov 15; 21(22): 4939–4947. Published online 2012 Aug 21. doi: 10.1093/hmg/dds337
PMCID:
PMC3607484
AbstractArticlePDF–355K
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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