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Items: 1 to 20 of 227

1.
Astrocytic DLL4-NOTCH1 signaling pathway promotes neuroinflammation via the IL-6-STAT3 axis
Pierre Mora, Margaux Laisné, Célia Bourguignon, Paul Rouault, Béatrice Jaspard-Vinassa, Marlène Maître, Alain-Pierre Gadeau, Marie-Ange Renault, Sam Horng, Thierry Couffinhal, Candice Chapouly
J Neuroinflammation. 2024; 21: 258. Published online 2024 Oct 10. doi: 10.1186/s12974-024-03246-w
PMCID:
PMC11468415
AbstractArticlePDF–20M
2.
KLF13 restrains Dll4‐muscular Notch2 axis to improve the muscle atrophy
Shu Yang, Lijiao Xiong, Guangyan Yang, Jiaqing Xiang, Lixing Li, Lin Kang, Zhen Liang
J Cachexia Sarcopenia Muscle. 2024 Oct; 15(5): 1869–1882. Published online 2024 Jul 8. doi: 10.1002/jcsm.13538
PMCID:
PMC11446702
AbstractArticlePDF–4.0M
3.
Vhl safeguards thymic epithelial cell identity and thymopoietic capacity by constraining Hif1a activity during development
Christiane Grammer, Julia A. Komorowska, Jeremy B. Swann
iScience. 2024 Jul 19; 27(7): 110258. Published online 2024 Jun 13. doi: 10.1016/j.isci.2024.110258
PMCID:
PMC11261450
AbstractArticlePDF–11M
4.
Angiogenesis is uncoupled from osteogenesis during calvarial bone regeneration
M. Gabriele Bixel, Kishor K. Sivaraj, Melanie Timmen, Vishal Mohanakrishnan, Anusha Aravamudhan, Susanne Adams, Bong-Ihn Koh, Hyun-Woo Jeong, Kai Kruse, Richard Stange, Ralf H. Adams
Nat Commun. 2024; 15: 4575. Published online 2024 Jun 4. doi: 10.1038/s41467-024-48579-5
PMCID:
PMC11150404
AbstractArticlePDF–9.1M
5.
IκBα controls dormancy in hematopoietic stem cells via retinoic acid during embryonic development
Roshana Thambyrajah, Maria Maqueda, Muhammad Zaki Fadlullah, Martin Proffitt, Wen Hao Neo, Yolanda Guillén, Marta Casado-Pelaez, Patricia Herrero-Molinero, Carla Brujas, Noemi Castelluccio, Jessica González, Arnau Iglesias, Laura Marruecos, Cristina Ruiz-Herguido, Manel Esteller, Elisabetta Mereu, Georges Lacaud, Lluis Espinosa, Anna Bigas
Nat Commun. 2024; 15: 4673. Published online 2024 Jun 1. doi: 10.1038/s41467-024-48854-5
PMCID:
PMC11144194
AbstractArticlePDF–3.9M
6.
Cis inhibition of NOTCH1 through JAGGED1 sustains embryonic hematopoietic stem cell fate
Roshana Thambyrajah, Maria Maqueda, Wen Hao Neo, Kathleen Imbach, Yolanda Guillén, Daniela Grases, Zaki Fadlullah, Stefano Gambera, Francesca Matteini, Xiaonan Wang, Fernando J. Calero-Nieto, Manel Esteller, Maria Carolina Florian, Eduard Porta, Rui Benedito, Berthold Göttgens, Georges Lacaud, Lluis Espinosa, Anna Bigas
Nat Commun. 2024; 15: 1604. Published online 2024 Feb 21. doi: 10.1038/s41467-024-45716-y
PMCID:
PMC10882055
AbstractArticlePDF–6.6M
7.
PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development
Jong Geol Lee, Jung-Min Yon, Globinna Kim, Seul-Gi Lee, C-Yoon Kim, Seung-A Cheong, Hyun-Yi Kim, Jiyoung Yu, Kyunggon Kim, Young Hoon Sung, Hyun Ju Yoo, Dong-Cheol Woo, Jin Kyung Rho, Chang Hoon Ha, Chan-Gi Pack, Seak Hee Oh, Joon Seo Lim, Yu Mi Han, Eui-Ju Hong, Je Kyung Seong, Han-Woong Lee, Sang-Wook Lee, Ki-Up Lee, Chong Jai Kim, Sang-Yoon Nam, You Sook Cho, In-Jeoung Baek
Nat Commun. 2024; 15: 1487. Published online 2024 Feb 19. doi: 10.1038/s41467-024-45647-8
PMCID:
PMC10876648
AbstractArticlePDF–10M
8.
Palmitic acid in type 2 diabetes mellitus promotes atherosclerotic plaque vulnerability via macrophage Dll4 signaling
Xiqiang Wang, Ling Zhu, Jing Liu, Yanpeng Ma, Chuan Qiu, Chengfeng Liu, Yangchao Gong, Ya Yuwen, Gongchang Guan, Yong Zhang, Shuo Pan, Junkui Wang, Zhongwei Liu
Nat Commun. 2024; 15: 1281. Published online 2024 Feb 12. doi: 10.1038/s41467-024-45582-8
PMCID:
PMC10861578
AbstractArticlePDF–4.5M
9.
eNOS plays essential roles in the developing heart and aorta linked to disruption of Notch signalling
Lorraine Eley, Rachel V. Richardson, Ahlam Alqahtani, Bill Chaudhry, Deborah J. Henderson
Dis Model Mech. 2024 Jan 1; 17(1): dmm050265. Published online 2024 Jan 22. doi: 10.1242/dmm.050265
PMCID:
PMC10846539
AbstractArticle
10.
PRDM16 regulates arterial development and vascular integrity
Michael Thompson, Masahide Sakabe, Mark Verba, Jiukuan Hao, Stryder M. Meadows, Q. Richard Lu, Mei Xin
Front Physiol. 2023; 14: 1165379. Published online 2023 Jun 1. doi: 10.3389/fphys.2023.1165379
PMCID:
PMC10267475
AbstractArticlePDF–4.4M
11.
Epsin1-mediated exosomal sorting of Dll4 modulates the tubular-macrophage crosstalk in diabetic nephropathy
Jia-Lu Liu, Lei Zhang, Ying Huang, Xiao-Hui Li, Yi-Fei Liu, Shu-Min Zhang, Yue-E Zhao, Xiao-Jun Chen, Yu Liu, Li-Yu He, Zheng Dong, Fu-You Liu, Lin Sun, Li Xiao
Mol Ther. 2023 May 3; 31(5): 1451–1467. Published online 2023 Apr 3. doi: 10.1016/j.ymthe.2023.03.027
PMCID:
PMC10188907
AbstractArticlePDF–8.5M
12.
Notch1 and Notch4 core binding domain peptibodies exhibit distinct ligand-binding and anti-angiogenic properties
Timothy Sargis, Seock-Won Youn, Krishna Thakkar, L. A. Naiche, Na Yoon Paik, Kostandin V. Pajcini, Jan K. Kitajewski
Angiogenesis. 2023; 26(2): 249–263. Published online 2022 Nov 15. doi: 10.1007/s10456-022-09861-6
PMCID:
PMC10119233
AbstractArticlePDF–5.8M
13.
PI(4,5)P2-dependent regulation of endothelial tip cell specification contributes to angiogenesis
Elizabeth M. Davies, Rajendra Gurung, Kai Qin Le, Katherine T. T. Roan, Richard P. Harvey, Geraldine M. Mitchell, Quenten Schwarz, Christina A. Mitchell
Sci Adv. 2023 Mar; 9(13): eadd6911. Published online 2023 Mar 31. doi: 10.1126/sciadv.add6911
PMCID:
PMC10065449
AbstractArticlePDF–3.5M
14.
Loss of function of the maternal membrane oestrogen receptor ERα alters expansion of trophoblast cells and impacts mouse fertility
Mariam Rusidzé, Mélanie C. Faure, Pierre Sicard, Isabelle Raymond-Letron, Frank Giton, Emilie Vessieres, Vincent Prevot, Daniel Henrion, Jean-François Arnal, Charlotte A. Cornil, Françoise Lenfant
Development. 2022 Oct 1; 149(19): dev200683. Published online 2022 Oct 13. doi: 10.1242/dev.200683
PMCID:
PMC9720743
AbstractArticle
15.
Delta‐like ligand‐4 regulates Notch‐mediated maturation of second heart field progenitor‐derived pharyngeal arterial endothelial cells
Prashan De Zoysa, Omar Toubat, Drayton C. Harvey, Christopher Yi, Jiang Liu, Susana Cavallero, Young‐Kwon Hong, Henry M. Sucov, Subramanyan Ram Kumar
J Cell Mol Med. 2022 Oct; 26(20): 5181–5194. Published online 2022 Sep 9. doi: 10.1111/jcmm.17542
PMCID:
PMC9575135
AbstractArticlePDF–19M
16.
Limits to in vivo fate changes of epithelia in thymus and parathyroid by ectopic expression of transcription factors Gcm2 and Foxn1
Daisuke Nagakubo, Mayumi Hirakawa, Norimasa Iwanami, Thomas Boehm
Sci Rep. 2022; 12: 13554. Published online 2022 Aug 8. doi: 10.1038/s41598-022-17844-2
PMCID:
PMC9360016
AbstractArticlePDF–4.8M
17.
Dll4 Inhibition Promotes Graft Retention in Fat Grafting Enriched with Adipose-Derived Stem Cells
Choong-kun Lee, Bo-Yoon Park, Taehee Jo, Cheol-Heum Park, Ju-Hee Kim, Kyu-Jin Chung, Yong-Ha Kim, Do Young Park, Il-Kug Kim
Stem Cells Transl Med. 2022 Jul; 11(7): 742–752. Published online 2022 May 17. doi: 10.1093/stcltm/szac034
PMCID:
PMC9299511
AbstractArticlePDF–79M
18.
A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs
Yan Ting Shue, Alexandros P. Drainas, Nancy Yanzhe Li, Sarah M. Pearsall, Derrick Morgan, Nasa Sinnott-Armstrong, Susan Q. Hipkins, Garry L. Coles, Jing Shan Lim, Anthony E. Oro, Kathryn L. Simpson, Caroline Dive, Julien Sage
Nat Commun. 2022; 13: 2690. Published online 2022 May 16. doi: 10.1038/s41467-022-30416-2
PMCID:
PMC9110333
AbstractArticlePDF–7.0M
19.
Unique functions for Notch4 in murine embryonic lymphangiogenesis
Ajit Muley, Minji Kim Uh, Glicella Salazar-De Simone, Bhairavi Swaminathan, Jennifer M. James, Aino Murtomaki, Seock Won Youn, Joseph D. McCarron, Chris Kitajewski, Maria Gnarra Buethe, Gloria Riitano, Yoh-suke Mukouyama, Jan Kitajewski, Carrie J. Shawber
Angiogenesis. 2022; 25(2): 205–224. Published online 2021 Oct 19. doi: 10.1007/s10456-021-09822-5
PMCID:
PMC9054879
AbstractArticlePDF–6.8M
20.
FOXO1 represses sprouty 2 and sprouty 4 expression to promote arterial specification and vascular remodeling in the mouse yolk sac
Nanbing Li-Villarreal, Rebecca Lee Yean Wong, Monica D. Garcia, Ryan S. Udan, Ross A. Poché, Tara L. Rasmussen, Alexander M. Rhyner, Joshua D. Wythe, Mary E. Dickinson
Development. 2022 Apr 1; 149(7): dev200131. Published online 2022 Apr 1. doi: 10.1242/dev.200131
PMCID:
PMC8995087
AbstractArticle

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