U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO Profiles

Items: 1 to 20 of 44

1.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
2.
Humanized liver TK-NOG mice with functional deletion of hepatic murine cytochrome P450s as a model for studying human drug metabolism
Shotaro Uehara, Yuichi Iida, Miyuki Ida-Tanaka, Motohito Goto, Kenji Kawai, Masafumi Yamamoto, Yuichiro Higuchi, Satoshi Ito, Riichi Takahashi, Hidetaka Kamimura, Mamoru Ito, Hiroshi Yamazaki, Mitsuo Oshimura, Yasuhiro Kazuki, Hiroshi Suemizu
Sci Rep. 2022; 12: 14907. Published online 2022 Sep 1. doi: 10.1038/s41598-022-19242-0
PMCID:
PMC9437039
AbstractArticlePDF–2.0M
3.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
4.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
5.
Application of a novel regulatable Cre recombinase system to define the role of liver and gut metabolism in drug oral bioavailability
Colin J. Henderson, Lesley A. McLaughlin, Maria Osuna-Cabello, Malcolm Taylor, Ian Gilbert, Aileen W. McLaren, C. Roland Wolf
Biochem J. Author manuscript; available in PMC 2020 Jan 8.
Published in final edited form as: Biochem J. 2015 Feb 1; 465(3): 479–488. doi: 10.1042/BJ20140582
PMCID:
PMC6949133
AbstractArticlePDF–1.5M
6.
Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine
Lindsay Reed, Radek Indra, Iveta Mrizova, Michaela Moserova, Heinz H. Schmeiser, C. Roland Wolf, Colin J. Henderson, Marie Stiborova, David H. Phillips, Volker M. Arlt
Toxicol Appl Pharmacol. 2019 Mar 1; 366: 64–74. doi: 10.1016/j.taap.2019.01.020
PMCID:
PMC6382462
AbstractArticle
7.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
8.
A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism
Mercedes Barzi, Francis P. Pankowicz, Barry Zorman, Xing Liu, Xavier Legras, Diane Yang, Malgorzata Borowiak, Beatrice Bissig-Choisat, Pavel Sumazin, Feng Li, Karl-Dimiter Bissig
Nat Commun. 2017; 8: 39. Published online 2017 Jun 28. doi: 10.1038/s41467-017-00049-x
Correction in:
Nat Commun. 2017; 8: 984.
PMCID:
PMC5489481
AbstractArticlePDF–2.3M
9.
Oscillating primary transcripts harbor miRNAs with circadian functions
Haifang Wang, Zenghua Fan, Meng Zhao, Juan Li, Minghua Lu, Wei Liu, Hao Ying, Mofang Liu, Jun Yan
Sci Rep. 2016; 6: 21598. Published online 2016 Feb 22. doi: 10.1038/srep21598
PMCID:
PMC4761921
AbstractArticlePDF–1.7M
10.
Significance of Neuronal Cytochrome P450 Activity in Opioid-Mediated Stress-Induced Analgesia
Lindsay B. Hough, Julia W. Nalwalk, Weizhu Yang, Xinxin Ding
Brain Res. Author manuscript; available in PMC 2015 Aug 26.
Published in final edited form as: Brain Res. 2014 Aug 26; 1578: 30–37. Published online 2014 Jul 11. doi: 10.1016/j.brainres.2014.07.007
PMCID:
PMC4143908
AbstractArticlePDF–320K
11.
Mice Deficient in Intestinal Epithelium Cytochrome P450 Reductase are Prone to Acute Toxin-induced Mucosal Damage
Sarita Ahlawat, Fang Xie, Yi Zhu, Rebecca D'Hondt, Xinxin Ding, Qing-Yu Zhang, Nicholas J. Mantis
Sci Rep. 2014; 4: 5551. Published online 2014 Jul 3. doi: 10.1038/srep05551
PMCID:
PMC4080431
AbstractArticlePDF–1.2M
12.
Pyrethroid activity-based probes for profiling cytochrome P450 activities associated with insecticide interactions
Hanafy M. Ismail, Paul M. O’Neill, David W. Hong, Robert D. Finn, Colin J. Henderson, Aaron T. Wright, Benjamin F. Cravatt, Janet Hemingway, Mark J. I. Paine
Proc Natl Acad Sci U S A. 2013 Dec 3; 110(49): 19766–19771. Published online 2013 Nov 18. doi: 10.1073/pnas.1320185110
PMCID:
PMC3856776
AbstractArticlePDF–841K
13.
Conditional Deletion of Cytochrome P450 Reductase in Osteoprogenitor Cells Affects Long Bone and Skull Development in Mice Recapitulating Antley-Bixler Syndrome: Role of a Redox Enzyme in Development
Satya P. Panda, Anyonya R. Guntur, Srikanth R. Polusani, Roberto J. Fajardo, Peter T. Gakunga, Linda J. Roman, Bettie Sue Masters
PLoS One. 2013; 8(9): e75638. Published online 2013 Sep 25. doi: 10.1371/journal.pone.0075638
PMCID:
PMC3783497
AbstractArticlePDF–3.4M
14.
The role of renal proximal tubule P450 enzymes in chloroform-induced nephrotoxicity: utility of renal specific P450 reductase knockout mouse models
Senyan Liu, Yunyi Yao, Shijun Lu, Kenneth Aldous, Xinxin Ding, Changlin Mei, Jun Gu
Toxicol Appl Pharmacol. Author manuscript; available in PMC 2014 Oct 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2013 Oct 1; 272(1): 230–237. Published online 2013 Jun 1. doi: 10.1016/j.taap.2013.05.022
PMCID:
PMC3775882
AbstractArticlePDF–2.7M
15.
Suppression of cytochrome P450 reductase expression promotes astrocytosis in subventricular zone of adult mice
Yunyi Yao, Senyan Liu, Yue Wang, Weiping Yuan, Xinxin Ding, Tao Cheng, Qin Shen, Jun Gu
Neurosci Lett. Author manuscript; available in PMC 2014 Aug 26.
Published in final edited form as: Neurosci Lett. 2013 Aug 26; 548: 84–89. Published online 2013 May 30. doi: 10.1016/j.neulet.2013.05.043
PMCID:
PMC3731042
AbstractArticlePDF–2.1M
16.
Suppression of Cytochrome P450 Reductase Enhances Long-Term Hematopoietic Stem Cell Repopulation Efficiency in Mice
Yan Zhang, Fang Dong, Na Zhang, Hui Cheng, Yakun Pang, Xiaomin Wang, Jing Xu, Xinxin Ding, Tao Cheng, Jun Gu, Weiping Yuan
PLoS One. 2013; 8(7): e69913. Published online 2013 Jul 26. doi: 10.1371/journal.pone.0069913
PMCID:
PMC3724780
AbstractArticlePDF–2.5M
17.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
18.
Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism
Sabrina A. Bardowell, Xinxin Ding, Robert S. Parker
J Lipid Res. 2012 Dec; 53(12): 2667–2676. doi: 10.1194/jlr.M030734
PMCID:
PMC3494260
AbstractArticlePDF–1.0M
19.
Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain
Dyna I. Shirasaki, Erin R. Greiner, Ismael Al-Ramahi, Michelle Gray, Pinmanee Boontheung, Daniel H. Geschwind, Juan Botas, Giovanni Coppola, Steve Horvath, Joseph A. Loo, X. William Yang
Neuron. Author manuscript; available in PMC 2013 Jul 12.
Published in final edited form as: Neuron. 2012 Jul 12; 75(1): 41–57. doi: 10.1016/j.neuron.2012.05.024
PMCID:
PMC3432264
AbstractArticlePDF–4.9M
20.
Neurobehavioral abnormalities in a brain-specific NADPH-cytochrome P450 reductase knockout mouse model
Cheng Fang, Valerie J. Bolivar, Jun Gu, Weizhu Yang, Scott O. Zeitlin, Xinxin Ding
Neuroscience. Author manuscript; available in PMC 2013 Aug 30.
Published in final edited form as: Neuroscience. 2012 Aug 30; 218: 170–180. Published online 2012 May 22. doi: 10.1016/j.neuroscience.2012.05.027
PMCID:
PMC3393838
AbstractArticlePDF–1.0M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

You are here: NCBI > Literature > PubMed Central (PMC)
Support Center