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Items: 1 to 20 of 46

1.
C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains
Julia Jülg, Dieter Edbauer, Christian Behrends
EMBO Rep. 2023 Aug; 24(8): e55895. Published online 2023 Jun 15. doi: 10.15252/embr.202255895
PMCID:
PMC10398660
AbstractArticlePDF–2.4M
2.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
3.
STRIP2 motivates non-small cell lung cancer progression by modulating the TMBIM6 stability through IGF2BP3 dependent
Xilin Zhang, Qiuqiang Chen, Ying He, Qian Shi, Chengyi Yin, Yanping Xie, Huanming Yu, Ying Bao, Xiang Wang, Chengwu Tang, Zhaohui Dong
J Exp Clin Cancer Res. 2023; 42: 19. Published online 2023 Jan 13. doi: 10.1186/s13046-022-02573-1
PMCID:
PMC9837939
AbstractArticlePDF–19M
4.
miR-302d-3p regulates the viability, migration and apoptosis of breast cancer cells through regulating the TMBIM6-mediated ERK signaling pathway
Yanru Liao, Zhenxiong Qiu, Ling Bai
Mol Med Rep. 2021 Dec; 24(6): 853. Published online 2021 Oct 14. doi: 10.3892/mmr.2021.12493
PMCID:
PMC8548939
AbstractArticlePDF–16M
5.
TMBIM6 regulates redox-associated posttranslational modifications of IRE1α and ER stress response failure in aging mice and humans
Kashi Raj Bhattarai, Hyun-Kyoung Kim, Manoj Chaudhary, Mohammad Mamun Ur Rashid, Jisun Kim, Hyung-Ryong Kim, Han-Jung Chae
Redox Biol. 2021 Nov; 47: 102128. Published online 2021 Sep 9. doi: 10.1016/j.redox.2021.102128
PMCID:
PMC8476450
AbstractArticlePDF–16M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
TMBIM6, a potential virus target protein identified by integrated multiomics data analysis in SARS-CoV-2-infected host cells
Qizheng Han, Junhao Wang, Haihua Luo, Lei Li, Xinya Lu, Aihua Liu, Yongqiang Deng, Yong Jiang
Aging (Albany NY) 2021 Apr 15; 13(7): 9160–9185. Published online 2021 Mar 19. doi: 10.18632/aging.202718
PMCID:
PMC8064151
AbstractArticlePDF–4.0M
8.
TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy through regulation of lysosomal calcium
Hyun-Kyoung Kim, Geum-Hwa Lee, Kashi Raj Bhattarai, Myung-Shik Lee, Sung Hoon Back, Hyung-Ryong Kim, Han-Jung Chae
Autophagy. 2021; 17(3): 761–778. Published online 2020 Mar 13. doi: 10.1080/15548627.2020.1732161
PMCID:
PMC8032251
AbstractArticlePDF–6.1M
9.
Quercetin Improves Cardiomyocyte Vulnerability to Hypoxia by Regulating SIRT1/TMBIM6-Related Mitophagy and Endoplasmic Reticulum Stress
Xing Chang, Tian Zhang, Qingyan Meng, ShiyuanWang, Peizheng Yan, Xue Wang, Duosheng Luo, XiuTeng Zhou, Ruifeng Ji
Oxid Med Cell Longev. 2021; 2021: 5529913. Published online 2021 Mar 29. doi: 10.1155/2021/5529913
PMCID:
PMC8024107
AbstractArticlePDF–4.8M
10.
RBM15 facilitates laryngeal squamous cell carcinoma progression by regulating TMBIM6 stability through IGF2BP3 dependent
Xin Wang, Linli Tian, Yushan Li, Jingting Wang, Bingrui Yan, Like Yang, Qiuying Li, Rui Zhao, Ming Liu, Peng Wang, Yanan Sun
J Exp Clin Cancer Res. 2021; 40: 80. Published online 2021 Feb 26. doi: 10.1186/s13046-021-01871-4
PMCID:
PMC7912894
AbstractArticlePDF–4.0M
11.
In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators
Jennifer L. Franks, Raquel C. Martinez-Chacin, Xianxi Wang, Rochelle L. Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L. Bolhuis, Taylor P. Enrico, Ryan D. Mouery, Jeffrey S. Damrauer, Feng Yan, Joseph S. Harrison, M. Ben Major, Katherine A. Hoadley, Aussie Suzuki, Scott B. Rothbart, Nicholas G. Brown, Michael J. Emanuele
PLoS Biol. 2020 Dec; 18(12): e3000975. Published online 2020 Dec 11. doi: 10.1371/journal.pbio.3000975
PMCID:
PMC7758050
AbstractArticlePDF–4.2M
12.
PARK2 promotes mitochondrial pathway of apoptosis and antimicrotubule drugs chemosensitivity via degradation of phospho-BCL-2
Hengxing Chen, Yun Li, Yu Li, Zhen Chen, Limin Xie, Wenjia Li, Yuanxin Zhu, Hong Xue, H. Phillip Koeffler, Wenjing Wu, Kaishun Hu, Dong Yin
Theranostics. 2020; 10(22): 9984–10000. Published online 2020 Aug 8. doi: 10.7150/thno.47044
PMCID:
PMC7481404
AbstractArticlePDF–4.0M
13.
TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation
Hyun-Kyoung Kim, Kashi Raj Bhattarai, Raghu Patil Junjappa, Jin Hee Ahn, Suvarna H. Pagire, Hyun Ju Yoo, Jaeseok Han, Duckgue Lee, Kyung-Woon Kim, Hyung-Ryong Kim, Han-Jung Chae
Nat Commun. 2020; 11: 4012. Published online 2020 Aug 11. doi: 10.1038/s41467-020-17802-4
PMCID:
PMC7419509
AbstractArticlePDF–4.7M
14.
Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling
Emma J Fenech, Federica Lari, Philip D Charles, Roman Fischer, Marie Laétitia-Thézénas, Katrin Bagola, Adrienne W Paton, James C Paton, Mads Gyrd-Hansen, Benedikt M Kessler, John C Christianson
eLife. 2020; 9: e57306. Published online 2020 Jul 2. doi: 10.7554/eLife.57306
PMCID:
PMC7332293
AbstractArticlePDF–2.2M
15.
Bax Inhibitor-1: between stress and survival
Cynthia Lebeaupin, Marina Blanc, Déborah Vallée, Harald Keller, Béatrice Bailly-Maitre
FEBS J. Author manuscript; available in PMC 2021 May 1.
Published in final edited form as: FEBS J. 2020 May; 287(9): 1722–1736. Published online 2020 Jan 8. doi: 10.1111/febs.15179
PMCID:
PMC7202976
AbstractArticlePDF–662K
16.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
17.
Bax inhibitor 1 preserves mitochondrial homeostasis in acute kidney injury through promoting mitochondrial retention of PHB2
Jin Wang, Pingjun Zhu, Ruibing Li, Jun Ren, Yingmei Zhang, Hao Zhou
Theranostics. 2020; 10(1): 384–397. Published online 2020 Jan 1. doi: 10.7150/thno.40098
PMCID:
PMC6929616
AbstractArticlePDF–3.9M
18.
Bax inhibitor 1 is a γ-secretase–independent presenilin-binding protein
Shenjie Wu, Wenqi Song, Catherine C. L. Wong, Yigong Shi
Proc Natl Acad Sci U S A. 2019 Jan 2; 116(1): 141–147. Published online 2018 Dec 17. doi: 10.1073/pnas.1810870116
PMCID:
PMC6320538
AbstractArticlePDF–1.8M
19.
Nuclear export of ubiquitinated proteins via the UBIN-POST system
Shoshiro Hirayama, Munechika Sugihara, Daisuke Morito, Shun-ichiro Iemura, Tohru Natsume, Shigeo Murata, Kazuhiro Nagata
Proc Natl Acad Sci U S A. 2018 May 1; 115(18): E4199–E4208. Published online 2018 Apr 16. doi: 10.1073/pnas.1711017115
PMCID:
PMC5939056
AbstractArticlePDF–1.8M
20.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M

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