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Select item 97570941.

Transcriptional Circuitry of NKX2-1 and SOX1 Defines an Unrecognized Lineage Subtype of Small-Cell Lung Cancer

Ranran Kong, Ayushi S. Patel, Takashi Sato, Feng Jiang, Seungyeul Yoo, Li Bao, Abhilasha Sinha, Yang Tian, Maya Fridrikh, Shuhui Liu, Jie Feng, Xijing He, Jiantao Jiang, Yuefeng Ma, Karina Grullon, Dawei Yang, Charles A. Powell, Mary Beth Beasley, Jun Zhu, Eric L. Snyder, Shaomin Li, Hideo Watanabe

Am J Respir Crit Care Med. 2022 Dec 15; 206(12): 1480–1494. Published online 2022 Jul 18. doi: 10.1164/rccm.202110-2358OC

PMCID:: PMC9757094

Abstract Article PDF–3.5M

Select item 85664732.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

Select item 81650303.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 77387924.

SOX1 and PAX1 Are Hypermethylated in Cervical Adenocarcinoma and Associated with Better Prognosis

Zitong Zhao, Xiaoye Zhang, Xueheng Zhao, Jingting Cai, Na-Yi Yuan Wu, Jing Wang

Biomed Res Int. 2020; 2020: 3981529. Published online 2020 Dec 7. doi: 10.1155/2020/3981529

PMCID:: PMC7738792

Abstract Article PDF–529K

Select item 76968895.

In Silico Identification of SOX1 Post-Translational Modifications Highlights a Shared Protein Motif

Azaz Ahmad, Stephanie Strohbuecker, Claudia Scotti, Cristina Tufarelli, Virginie Sottile

Cells. 2020 Nov; 9(11): 2471. Published online 2020 Nov 13. doi: 10.3390/cells9112471

PMCID:: PMC7696889

Abstract Article PDF–2.2M

Select item 72061106.

SOX1 promotes differentiation of nasopharyngeal carcinoma cells by activating retinoid metabolic pathway

Xin-Xing Lei, Yun Liu, Jin-Xing Wang, Qian Cai, Min Yan, Hui-Ping He, Quentin Liu, Zi-Jie Long, Zhong Guan

Cell Death Dis. 2020 May; 11(5): 331. Published online 2020 May 7. doi: 10.1038/s41419-020-2513-1

PMCID:: PMC7206110

Abstract Article PDF–3.2M

Select item 67566317.

Tumor-suppressor gene SOX1 is a methylation-specific expression gene in cervical adenocarcinoma

Min Yuan, Lili Yao, Guzhalinuer Abulizi

Medicine (Baltimore) 2019 Sep; 98(38): e17225. Published online 2019 Sep 20. doi: 10.1097/MD.0000000000017225

PMCID:: PMC6756631

Abstract Article PDF–602K

Select item 66334338.

Sox1 Is Required for the Specification of a Novel p2-Derived Interneuron Subtype in the Mouse Ventral Spinal Cord

Helen Panayi, Elena Panayiotou, Michael Orford, Nicolas Genethliou, Richard Mean, George Lapathitis, Shengguo Li, Mengqing Xiang, Nicoletta Kessaris, William D. Richardson, Stavros Malas

J Neurosci. 2010 Sep 15; 30(37): 12274–12280. doi: 10.1523/JNEUROSCI.2402-10.2010

PMCID:: PMC6633433

Abstract Article PDF–2.4M

Select item 63338839.

Proteolysis of methylated SOX2 protein is regulated by L3MBTL3 and CRL4^DCAF5 ubiquitin ligase

Chunxiao Zhang, Feng Leng, Lovely Saxena, Nam Hoang, Jiekai Yu, Salvador Alejo, Logan Lee, Dandan Qi, Fei Lu, Hong Sun, Hui Zhang

J Biol Chem. 2019 Jan 11; 294(2): 476–489. Published online 2018 Nov 15. doi: 10.1074/jbc.RA118.005336

PMCID:: PMC6333883

Abstract Article PDF–3.1M

Select item 564128010.

Expression of a SOX1 overlapping transcript in neural differentiation and cancer models

Azaz Ahmad, Stephanie Strohbuecker, Cristina Tufarelli, Virginie Sottile

Cell Mol Life Sci. 2017 Nov; 74(22): 4245–4258. Published online 2017 Jul 3. doi: 10.1007/s00018-017-2580-3

PMCID:: PMC5641280

Abstract Article PDF–3.1M

Select item 553161111.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 539786112.

Oncogenic activity of SOX1 in glioblastoma

Idoia Garcia, Juncal Aldaregia, Jelena Marjanovic Vicentic, Paula Aldaz, Leire Moreno-Cugnon, Sergio Torres-Bayona, Estefania Carrasco-Garcia, Laura Garros-Regulez, Larraitz Egaña, Angel Rubio, Steven Pollard, Milena Stevanovic, Nicolas Sampron, Ander Matheu

Sci Rep. 2017; 7: 46575. Published online 2017 Apr 20. doi: 10.1038/srep46575

PMCID:: PMC5397861

Abstract Article PDF–1.8M

Select item 459125313.

Sox10 regulates stem/progenitor and mesenchymal cell states in mammary epithelial cells

Christopher Dravis, Benjamin T. Spike, J. Chuck Harrell, Claire Johns, Christy L. Trejo, E. Michelle Southard-Smith, Charles M. Perou, Geoffrey M. Wahl

Cell Rep. Author manuscript; available in PMC 2016 Sep 29.

Published in final edited form as: Cell Rep. 2015 Sep 29; 12(12): 2035–2048. Published online 2015 Sep 10. doi: 10.1016/j.celrep.2015.08.040

PMCID:: PMC4591253

Abstract Article PDF–2.1M

Select item 450311514.

Prognostic significance of SOX-1 expression in human hepatocelluar cancer

Jinshu Lou, Kai Zhang, Jing Chen, Yanping Gao, Rui Wang, Long-Bang Chen

Int J Clin Exp Pathol. 2015; 8(5): 5411–5418. Published online 2015 May 1.

PMCID:: PMC4503115

Abstract Article PDF–931K

Select item 449848315.

Dissecting genetics for chronic mucus hypersecretion in smokers with and without COPD: genome wide analysis on mucus hypersecretion

Akkelies E. Dijkstra, H. Marike Boezen, Maarten van den Berge, Judith M. Vonk, Pieter S. Hiemstra, R. Graham Barr, Kirsten M. Burkart, Ani Manichaikul, Tess D. Pottinger, Edwin K. Silverman, Michael H. Cho, James D. Crapo, Terri H. Beaty, Per Bakke, Amund Gulsvik, David A. Lomas, Yohan Bossé, David C. Nickle, Peter D. Paré, Harry J. de Koning, Jan-Willem Lammers, Pieter Zanen, Joanna Smolonska, Ciska Wijmenga, Corry-Anke Brandsma, Harry J.M. Groen, Dirkje S. Postma

Eur Respir J. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Eur Respir J. 2015 Jan; 45(1): 60–75. Published online 2014 Sep 18. doi: 10.1183/09031936.00093314

PMCID:: PMC4498483

Abstract Article PDF–1.2M

Select item 432652516.

SOX1 down-regulates β-catenin and reverses malignant phenotype in nasopharyngeal carcinoma

Zhong Guan, Jialiang Zhang, Jing Wang, Hefei Wang, Feimeng Zheng, Jieren Peng, Yaodong Xu, Min Yan, Bing Liu, Bai Cui, Ying Huang, Quentin Liu

Mol Cancer. 2014; 13: 257. Published online 2014 Nov 26. doi: 10.1186/1476-4598-13-257

PMCID:: PMC4326525

Abstract Article PDF–1.8M

Select item 430317517.

PAX1/SOX1 DNA methylation and cervical neoplasia detection: a Taiwanese Gynecologic Oncology Group (TGOG) study

Hung-Cheng Lai, Yu-Che Ou, Tze-Chien Chen, Huei-Jean Huang, Ya-Min Cheng, Chi-Hau Chen, Tang-Yuan Chu, Shih-Tien Hsu, Cheng-Bin Liu, Yao-Ching Hung, Kuo-Chang Wen, Mu-Hsien Yu, Kung-Liahng Wang

Cancer Med. 2014 Aug; 3(4): 1062–1074. Published online 2014 May 3. doi: 10.1002/cam4.253

PMCID:: PMC4303175

Abstract Article PDF–872K

Select item 392933518.

Generation of Highly Purified Neural Stem Cells from Human Adipose-Derived Mesenchymal Stem Cells by Sox1 Activation

Nianhua Feng, Qin Han, Jing Li, Shihua Wang, Hongling Li, Xinglei Yao, Robert Chunhua Zhao

Stem Cells Dev. 2014 Mar 1; 23(5): 515–529. Published online 2013 Oct 18. doi: 10.1089/scd.2013.0263

PMCID:: PMC3929335

Abstract Article PDF–1.7M

Select item 340038419.

DMH1, a Highly Selective Small Molecule BMP Inhibitor Promotes Neurogenesis of hiPSCs: Comparison of PAX6 and SOX1 Expression during Neural Induction

M. Diana Neely, Michael J. Litt, Andrew M. Tidball, Gary G. Li, Asad A. Aboud, Corey R. Hopkins, Reed Chamberlin, Charles C. Hong, Kevin C. Ess, Aaron B. Bowman

ACS Chem Neurosci. 2012 Jun 20; 3(6): 482–491. Published online 2012 Mar 5. doi: 10.1021/cn300029t

PMCID:: PMC3400384

Abstract Article PDF–3.3M

Select item 317805920.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

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