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Select item 111267001.

The E3 ubiquitin-protein ligase UHRF1 promotes adipogenesis and limits fibrosis by suppressing GPNMB-mediated TGF-β signaling

Muneera Vakayil, Aisha Y. Madani, Maha V. Agha, Yasser Majeed, Shahina Hayat, Shameem Yonuskunju, Yasmin Ali Mohamoud, Joel Malek, Karsten Suhre, Nayef A. Mazloum

Sci Rep. 2024; 14: 11886. Published online 2024 May 24. doi: 10.1038/s41598-024-62508-y

PMCID:: PMC11126700

Abstract Article PDF–8.0M

Select item 111032532.

GPNMB Promotes Tumor Growth and is a Biomarker for Lymphangioleiomyomatosis

Erin Gibbons, Manisha Taya, Huixing Wu, Samia H Lopa, Joel Moss, Elizabeth P Henske, Francis X McCormack, Stephen R Hammes

Endocr Relat Cancer. Author manuscript; available in PMC 2024 Jun 1.

Published in final edited form as: Endocr Relat Cancer. 2024 Jun 1; 31(6): e230312. Published online 2024 May 9. doi: 10.1530/ERC-23-0312

PMCID:: PMC11103253

Abstract Article PDF–2.0M

Select item 110285543.

The immune inhibitory receptor osteoactivin is upregulated in monocyte-derived dendritic cells by BCR–ABL tyrosine kinase inhibitors

Mark-Alexander Schwarzbich, Michael Gutknecht, Julia Salih, Helmut R. Salih, Peter Brossart, Susanne M. Rittig, Frank Grünebach

Cancer Immunol Immunother. 2012 Feb; 61(2): 193–202. Published online 2011 Aug 27. doi: 10.1007/s00262-011-1096-1

PMCID:: PMC11028554

Abstract Article PDF–589K

Select item 109859974.

Tumor associated microglia/macrophages utilize GPNMB to promote tumor growth and alter immune cell infiltration in glioma

Fatih Yalcin, Hannah Haneke, Ibrahim E. Efe, Leonard D. Kuhrt, Edyta Motta, Bernadette Nickl, Charlotte Flüh, Michael Synowitz, Omar Dzaye, Michael Bader, Helmut Kettenmann

Acta Neuropathol Commun. 2024; 12: 50. Published online 2024 Apr 2. doi: 10.1186/s40478-024-01754-7

PMCID:: PMC10985997

Abstract Article PDF–3.2M

Select item 109424675.

Mitochondrial Raf1 Regulates Glutamine Catabolism

Ronald L. Shanderson, Ian D. Ferguson, Zurab Siprashvili, Luca Ducoli, Albert M. Li, Weili Miao, Suhas Srinivasan, Mary Grace Velasco, Yang Li, Jiangbin Ye, Paul A. Khavari

Version 1. bioRxiv. Preprint. 2024 Mar 9. doi: 10.1101/2024.03.08.581297

PMCID:: PMC10942467

Abstract Article PDF–6.5M

Select item 107000206.

Glycoprotein Non-Metastatic Protein B (GPNMB): The Missing Link Between Lysosomes and Obesity

Valentina Bianco, Dagmar Kratky

Exp Clin Endocrinol Diabetes. 2023 Dec; 131(12): 639–645. Published online 2023 Nov 13. doi: 10.1055/a-2192-0101

PMCID:: PMC10700020

Abstract Article PDF–488K

Select item 106375527.

Prognostic evaluation of oral squamous cell carcinoma based on pleiotrophin, urokinase plasminogen activator, and glycoprotein nonmetastatic melanoma protein B expression

Yuxin Ma, Yue Liu, Han Meng

Medicine (Baltimore) 2023 Nov 10; 102(45): e35634. Published online 2023 Nov 10. doi: 10.1097/MD.0000000000035634

PMCID:: PMC10637552

Abstract Article PDF–1.6M

Select item 98700368.

GPNMB confers risk for Parkinson’s disease through interaction with alpha-synuclein

Maria E. Diaz-Ortiz, Yunji Seo, Marijan Posavi, Marc Carceles Cordon, Elisia Clark, Nimansha Jain, Rakshita Charan, Michael D. Gallagher, Travis L. Unger, Noor Amari, R. Tyler Skrinak, Roseanne Davila-Rivera, Eliza M. Brody, Noah Han, Rebecca Zack, Vivianna M. Van Deerlin, Thomas F. Tropea, Kelvin C. Luk, Edward B. Lee, Daniel Weintraub, Alice S. Chen-Plotkin

Science. Author manuscript; available in PMC 2023 Feb 19.

Published in final edited form as: Science. 2022 Aug 19; 377(6608): eabk0637. Published online 2022 Aug 19. doi: 10.1126/science.abk0637

PMCID:: PMC9870036

Abstract Article PDF–2.1M

Select item 94372059.

GPNMB-Positive Cells in Head and Neck Squamous Cell Carcinoma—Their Roles in Cancer Stemness, Therapy Resistance, and Metastasis

Yohei Kawasaki, Hitomi Suzuki, Shinsuke Suzuki, Takechiyo Yamada, Maya Suzuki, Ayumi Ito, Haruka Hatakeyama, Masahito Miura, Yasufumi Omori

Pathol Oncol Res. 2022; 28: 1610450. Published online 2022 Aug 19. doi: 10.3389/pore.2022.1610450

PMCID:: PMC9437205

Abstract Article PDF–3.0M

Select item 931078110.

GPNMB expression identifies TSC1/2/mTOR‐associated and MiT family translocation‐driven renal neoplasms

Daniela C Salles, Kaushal Asrani, Juhyung Woo, Thiago Vidotto, Hans B Liu, Igor Vidal, Andres Matoso, George J Netto, Pedram Argani, Tamara L Lotan

J Pathol. 2022 Jun; 257(2): 158–171. Published online 2022 Mar 29. doi: 10.1002/path.5875

PMCID:: PMC9310781

Abstract Article PDF–40M

Select item 910745511.

Glycoprotein nonmetastatic melanoma protein B (GNMPB) as a novel biomarker for cerebral adrenoleukodystrophy

Leyla A. Taghizadeh, Carina J. King, David R. Nascene, Ashish O. Gupta, Paul J. Orchard, LeeAnn Higgins, Todd W. Markowski, Erin E. Nolan, Justin W. Furcich, Troy C. Lund

Sci Rep. 2022; 12: 7985. Published online 2022 May 14. doi: 10.1038/s41598-022-11552-7

PMCID:: PMC9107455

Abstract Article PDF–1.8M

Select item 895155612.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Abstract Article PDF–4.4M

Select item 864002213.

Mapping the serum proteome to neurological diseases using whole genome sequencing

Grace Png, Andrei Barysenka, Linda Repetto, Pau Navarro, Xia Shen, Maik Pietzner, Eleanor Wheeler, Nicholas J. Wareham, Claudia Langenberg, Emmanouil Tsafantakis, Maria Karaleftheri, George Dedoussis, Anders Mälarstig, James F. Wilson, Arthur Gilly, Eleftheria Zeggini

Nat Commun. 2021; 12: 7042. Published online 2021 Dec 2. doi: 10.1038/s41467-021-27387-1

PMCID:: PMC8640022

Abstract Article PDF–11M

Select item 858884314.

Association Between Factors Involved in Bone Remodeling (Osteoactivin and OPG) With Plasma Levels of Irisin and Meteorin-Like Protein in People With T2D and Obesity

Preethi Cherian, Irina Al-Khairi, Mohammad Jamal, Suleiman Al-Sabah, Hamad Ali, Carol Dsouza, Eman Alshawaf, Waleed Al-Ali, Ghanim Al-Khaledi, Fahd Al-Mulla, Mohamed Abu-Farha, Jehad Abubaker

Front Endocrinol (Lausanne) 2021; 12: 752892. Published online 2021 Oct 29. doi: 10.3389/fendo.2021.752892

PMCID:: PMC8588843

Abstract Article PDF–1.4M

Select item 827369715.

Functional Domains and Evolutionary History of the PMEL and GPNMB Family Proteins

Paul W. Chrystal, Tim Footz, Elizabeth D. Hodges, Justin A. Jensen, Michael A. Walter, W. Ted Allison

Molecules. 2021 Jun; 26(12): 3529. Published online 2021 Jun 9. doi: 10.3390/molecules26123529

PMCID:: PMC8273697

Abstract Article PDF–10M

Select item 819009416.

Expression pattern and prognostic impact of glycoprotein non-metastatic B (GPNMB) in triple-negative breast cancer

Yu-Hsiang Huang, Pei-Yi Chu, Ji-Lin Chen, Chun-Teng Huang, Chi-Cheng Huang, Yi‐Fang Tsai, Yu-Ling Wang, Pei-Ju Lien, Ling-Ming Tseng, Chun-Yu Liu

Sci Rep. 2021; 11: 12171. Published online 2021 Jun 9. doi: 10.1038/s41598-021-91588-3

PMCID:: PMC8190094

Abstract Article PDF–4.7M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 802781418.

The soluble glycoprotein NMB (GPNMB) produced by macrophages induces cancer stemness and metastasis via CD44 and IL-33

M. Liguori, E. Digifico, A. Vacchini, R. Avigni, F. S. Colombo, E. M. Borroni, F. M. Farina, S. Milanesi, A. Castagna, L. Mannarino, I. Craparotta, S. Marchini, E. Erba, N. Panini, M. Tamborini, V. Rimoldi, P. Allavena, C. Belgiovine

Cell Mol Immunol. 2021 Mar; 18(3): 711–722. Published online 2020 Jul 29. doi: 10.1038/s41423-020-0501-0

PMCID:: PMC8027814

Abstract Article PDF–2.7M

Select item 796831619.

Long non‐coding RNA MALAT1 regulates cell proliferation and apoptosis via miR-135b-5p/GPNMB axis in Parkinson’s disease cell model

Kefeng Lv, Yuhua Liu, Yanbing Zheng, Shaowen Dai, Peifeng Yin, Haifeng Miao

Biol Res. 2021; 54: 10. Published online 2021 Mar 16. doi: 10.1186/s40659-021-00332-8

PMCID:: PMC7968316

Abstract Article PDF–3.1M

Select item 779515120.

Intracerebroventricular Treatment with 2-Hydroxypropyl-β-Cyclodextrin Decreased Cerebellar and Hepatic Glycoprotein Nonmetastatic Melanoma Protein B (GPNMB) Expression in Niemann–Pick Disease Type C Model Mice

Madoka Fukaura, Yoichi Ishitsuka, Seiichi Shirakawa, Naoki Ushihama, Yusei Yamada, Yuki Kondo, Toru Takeo, Naomi Nakagata, Keiichi Motoyama, Taishi Higashi, Hidetoshi Arima, Yuki Kurauchi, Takahiro Seki, Hiroshi Katsuki, Katsumi Higaki, Muneaki Matsuo, Tetsumi Irie

Int J Mol Sci. 2021 Jan; 22(1): 452. Published online 2021 Jan 5. doi: 10.3390/ijms22010452

PMCID:: PMC7795151

Abstract Article PDF–3.2M

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