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Select item 102374221.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 93920632.

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling

Yansheng Zhai, Xiaoyan Huang, Keren Zhang, Yuchen Huang, Yanlong Jiang, Jingwei Cui, Zhe Zhang, Cookson K. C. Chiu, Weiye Zhong, Gang Li

Nat Commun. 2022; 13: 4906. Published online 2022 Aug 20. doi: 10.1038/s41467-022-32689-z

PMCID:: PMC9392063

Abstract Article PDF–2.0M

Select item 92792853.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 89515564.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Abstract Article PDF–4.4M

Select item 84059965.

A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase

Emily Chen, Krystle Reiss, Dilip Shah, Ramu Manjula, Brandon Allen, Eva L. Murphy, James W. Murphy, Victor S. Batista, Vineet Bhandari, Elias J. Lolis, George P. Lisi

J Biol Chem. 2021 Sep; 297(3): 101061. Published online 2021 Aug 9. doi: 10.1016/j.jbc.2021.101061

PMCID:: PMC8405996

Abstract Article PDF–2.8M

Select item 83641816.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 81852247.

D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling

Shanshan Song, Bin Liu, Habibie Habibie, Jelle van den Bor, Martine J. Smit, Reinoud Gosens, Xinhui Wu, Corry-Anke Brandsma, Robbert H. Cool, Hidde J. Haisma, Gerrit J. Poelarends, Barbro N. Melgert

EBioMedicine. 2021 Jun; 68: 103412. Published online 2021 Jun 4. doi: 10.1016/j.ebiom.2021.103412

PMCID:: PMC8185224

Abstract Article PDF–3.3M

Select item 77956948.

Macrophage Migration Inhibitory Factor (MIF) and Its Homologue D-Dopachrome Tautomerase (DDT) Inversely Correlate with Inflammation in Discoid Lupus Erythematosus

Rosario Caltabiano, Rocco De Pasquale, Eliana Piombino, Giorgia Campo, Ferdinando Nicoletti, Eugenio Cavalli, Katia Mangano, Paolo Fagone

Molecules. 2021 Jan; 26(1): 184. Published online 2021 Jan 1. doi: 10.3390/molecules26010184

PMCID:: PMC7795694

Abstract Article PDF–2.7M

Select item 75524029.

Genetic regulation of gene expression of MIF family members in lung tissue

Laura Florez-Sampedro, Corry-Anke Brandsma, Maaike de Vries, Wim Timens, Rene Bults, Cornelis J. Vermeulen, Maarten van den Berge, Ma’en Obeidat, Philippe Joubert, David C. Nickle, Gerrit J. Poelarends, Alen Faiz, Barbro N. Melgert

Sci Rep. 2020; 10: 16980. Published online 2020 Oct 12. doi: 10.1038/s41598-020-74121-w

PMCID:: PMC7552402

Abstract Article PDF–1.4M

Select item 748475910.

CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage

Marie-Christine Albert, Kerstin Brinkmann, Wojciech Pokrzywa, Saskia Diana Günther, Martin Krönke, Thorsten Hoppe, Hamid Kashkar

Cell Death Dis. 2020 Sep; 11(9): 740. Published online 2020 Sep 10. doi: 10.1038/s41419-020-02923-x

PMCID:: PMC7484759

Abstract Article PDF–2.6M

Select item 729072111.

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation

Danielle G. May, Kelsey L. Scott, Alexandre R. Campos, Kyle J. Roux

Cells. 2020 May; 9(5): 1070. Published online 2020 Apr 25. doi: 10.3390/cells9051070

PMCID:: PMC7290721

Abstract Article PDF–9.2M

Select item 677791112.

Cardiomyocyte d-dopachrome tautomerase protects against heart failure

Yina Ma, Kevin N. Su, Daniel Pfau, Veena S. Rao, Xiaohong Wu, Xiaoyue Hu, Lin Leng, Xin Du, Marta Piecychna, Kenneth Bedi, Stuart G. Campbell, Anne Eichmann, Jeffrey M. Testani, Kenneth B. Margulies, Richard Bucala, Lawrence H. Young

JCI Insight. 2019 Sep 5; 4(17): e128900. Published online 2019 Sep 5. doi: 10.1172/jci.insight.128900

PMCID:: PMC6777911

Abstract Article PDF–7.4M

Select item 608158913.

Genetic Variant rs755622 Regulates Expression of the Multiple Sclerosis Severity Modifier D-Dopachrome Tautomerase in a Sex-Specific Way

Zhijie Han, Jiaojiao Qu, Jiehong Zhao, Xiao Zou

Biomed Res Int. 2018; 2018: 8285653. Published online 2018 Jul 24. doi: 10.1155/2018/8285653

PMCID:: PMC6081589

Abstract Article PDF–849K

Select item 581817414.

A global view of structure–function relationships in the tautomerase superfamily

Rebecca Davidson, Bert-Jan Baas, Eyal Akiva, Gemma L. Holliday, Benjamin J. Polacco, Jake A. LeVieux, Collin R. Pullara, Yan Jessie Zhang, Christian P. Whitman, Patricia C. Babbitt

J Biol Chem. 2018 Feb 16; 293(7): 2342–2357. Published online 2017 Nov 28. doi: 10.1074/jbc.M117.815340

PMCID:: PMC5818174

Abstract Article PDF–3.4M

Select item 549522515.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 506721516.

Modeling of both shared and distinct interactions between MIF and its homologue D-DT with their common receptor CD74

Roberto Meza-Romero, Gil Benedek, Kelley Jordan, Lin Leng, Georgios Pantouris, Elias Lolis, Richard Bucala, Arthur A Vandenbark

Cytokine. Author manuscript; available in PMC 2017 Dec 1.

Published in final edited form as: Cytokine. 2016 Dec; 88: 62–70. Published online 2016 Aug 27. doi: 10.1016/j.cyto.2016.08.024

PMCID:: PMC5067215

Abstract Article PDF–1.5M

Select item 501046617.

The Clinical Significance of the MIF Homolog D-Dopachrome Tautomerase (MIF-2) and its Circulating Receptor (sCD74) in Burn Injury

Bong-Sung Kim, Christian Stoppe, Gerrit Grieb, Lin Leng, Maor Sauler, David Assis, David Simons, Arne Hendrick Boecker, Wibke Schulte, Marta Piecychna, Stephan Hager, Jürgen Bernhagen, Norbert Pallua, Richard Bucala

Burns. Author manuscript; available in PMC 2017 Sep 1.

Published in final edited form as: Burns. 2016 Sep; 42(6): 1265–1276. Published online 2016 May 18. doi: 10.1016/j.burns.2016.02.005

PMCID:: PMC5010466

Abstract Article PDF–1.4M

Select item 461578018.

Interaction of MIF Family Proteins in Myocardial Ischemia/Reperfusion Damage and Their Influence on Clinical Outcome of Cardiac Surgery Patients

Christian Stoppe, Steffen Rex, Andreas Goetzenich, Sandra Kraemer, Christoph Emontzpohl, Josefin Soppert, Luisa Averdunk, Yu Sun, Rolf Rossaint, Hongqi Lue, Caleb Huang, Yan Song, Georgios Pantouris, Elias Lolis, Lin Leng, Wibke Schulte, Richard Bucala, Christian Weber, Jürgen Bernhagen

Antioxid Redox Signal. 2015 Oct 10; 23(11): 865–879. doi: 10.1089/ars.2014.6243