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Items: 1 to 20 of 362

1.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
2.
Comprehensive analysis of DNA repair gene polymorphisms and survival in patients with early stage non‐small‐cell lung cancer
Min Kim, Hyo‐Gyoung Kang, Shin Yup Lee, Hyung Cheol Lee, Eung Bae Lee, Yi Young Choi, Won Kee Lee, Sukki Cho, Guang Jin, Hyo‐Sung Jheon, Ji Woong Son, Myung‐Hoon Lee, Deuk Kju Jung, Seung Ick Cha, Chang Ho Kim, Young Mo Kang, Sin Kam, Tae Hoon Jung, Sanghoon Jheon, Jae Yong Park
Cancer Sci. 2010 Nov; 101(11): 2436–2442. Published online 2010 Jul 31. doi: 10.1111/j.1349-7006.2010.01699.x
PMCID:
PMC11159840
AbstractArticlePDF–209K
3.
Nanoscale Interaction of Endonuclease APE1 with DNA
Sridhar Vemulapalli, Mohtadin Hashemi, Yingling Chen, Suravi Pramanik, Kishor K. Bhakat, Yuri L. Lyubchenko
Int J Mol Sci. 2024 May; 25(10): 5145. Published online 2024 May 9. doi: 10.3390/ijms25105145
PMCID:
PMC11121393
AbstractArticlePDF–13M
4.
Live-cell imaging of human apurinic/apyrimidinic endonuclease 1 in the nucleus and nucleolus using a chaperone@DNA probe
Xiangjian Cao, Jinghui Zheng, Ruilan Zhang, Ying Sun, Meiping Zhao
Nucleic Acids Res. 2024 May 8; 52(8): e41. Published online 2024 Mar 30. doi: 10.1093/nar/gkae202
PMCID:
PMC11077052
AbstractArticlePDF–1.9M
5.
Apurinic/apyrimidinic endodeoxyribonuclease 1 (APE1) promotes stress granule formation via YBX1 phosphorylation in ovarian cancer
Shuyu Mao, Chong Xie, Yufeng Liu, Ye Zhao, Mengxia Li, Han Gao, Yue Xiao, Yongkang Zou, Zhiguo Zheng, Ya Gao, Juan Xie, Bing Tian, Liangyan Wang, Yuejin Hua, Hong Xu
Cell Mol Life Sci. 2024 Dec; 81(1): 113. Published online 2024 Mar 4. doi: 10.1007/s00018-023-05086-y
PMCID:
PMC10912283
AbstractArticlePDF–4.6M
6.
Back-Up Base Excision DNA Repair in Human Cells Deficient in the Major AP Endonuclease, APE1
Daria V. Kim, Evgeniia A. Diatlova, Timofey D. Zharkov, Vasily S. Melentyev, Anna V. Yudkina, Anton V. Endutkin, Dmitry O. Zharkov
Int J Mol Sci. 2024 Jan; 25(1): 64. Published online 2023 Dec 20. doi: 10.3390/ijms25010064
PMCID:
PMC10778768
AbstractArticlePDF–2.0M
7.
In vitro and In vivo evidence demonstrating chronic absence of Ref-1 Cysteine 65 impacts Ref-1 folding configuration, redox signaling, proliferation and metastasis in pancreatic cancer
M. Mijit, E. Kpenu, N.N. Chowdhury, S. Gampala, R. Wireman, S. Liu, O. Babb, M.M. Georgiadis, J. Wan, M.L. Fishel, M.R. Kelley
Redox Biol. 2024 Feb; 69: 102977. Published online 2023 Dec 1. doi: 10.1016/j.redox.2023.102977
PMCID:
PMC10749280
AbstractArticlePDF–6.6M
8.
Elevated APE1 dysregulates homologous recombination and cell cycle driving genomic evolution, tumorigenesis and chemoresistance in esophageal adenocarcinoma
Subodh Kumar, Jiangning Zhao, Srikanth Talluri, Leutz Buon, Shidai Mu, Bhavani Potluri, Chengcheng Liao, Jialan Shi, Chandraditya Chakraborty, Gabriel B. Gonzalez, Yu-Tzu Tai, Jaymin Patel, Jagannath Pal, Hiroshi Mashimo, Mehmet K. Samur, Nikhil C. Munshi, Masood A. Shammas
Gastroenterology. Author manuscript; available in PMC 2024 Aug 1.
Published in final edited form as: Gastroenterology. 2023 Aug; 165(2): 357–373. Published online 2023 May 12. doi: 10.1053/j.gastro.2023.04.035
PMCID:
PMC10524563
AbstractArticlePDF–1.3M
9.
AUF1 Recognizes 8-Oxo-Guanosine Embedded in DNA and Stimulates APE1 Endoribonuclease Activity
Matilde Clarissa Malfatti, Marta Codrich, Emiliano Dalla, Chiara D'Ambrosio, Francesca Storici, Andrea Scaloni, Gianluca Tell
Antioxid Redox Signal. September 2023; 39(7-9): 411–431. Published online 2023 Sep 14. doi: 10.1089/ars.2022.0105
PMCID:
PMC10517317
AbstractArticlePDF–1.3M
10.
Expression of Apurinic/Apyrimidinic Endonuclease 1 in Colorectal Cancer and its Relation to Tumor Progression and Prognosis
JI-YUN HONG, HYUNG-HOON OH, SUN-YOUNG PARK, YOUNG-LAN PARK, SUNG-BUM CHO*, YOUNG-EUN JOO
In Vivo. 2023 Sep-Oct; 37(5): 2070–2077. Published online 2023 Sep 3. doi: 10.21873/invivo.13304
PMCID:
PMC10500501
AbstractArticlePDF–2.2M
11.
Revisiting Two Decades of Research Focused on Targeting APE1 for Cancer Therapy: The Pros and Cons
Matilde Clarissa Malfatti, Alessia Bellina, Giulia Antoniali, Gianluca Tell
Cells. 2023 Jul; 12(14): 1895. Published online 2023 Jul 20. doi: 10.3390/cells12141895
PMCID:
PMC10378182
AbstractArticlePDF–3.7M
12.
Mechanistic insight into AP-endonuclease 1 cleavage of abasic sites at stalled replication fork mimics
Nicole M Hoitsma, Jessica Norris, Thu H Khoang, Vikas Kaushik, Rahul Chadda, Edwin Antony, Mark Hedglin, Bret D Freudenthal
Nucleic Acids Res. 2023 Jul 21; 51(13): 6738–6753. Published online 2023 Jun 2. doi: 10.1093/nar/gkad481
PMCID:
PMC10359615
AbstractArticlePDF–2.0M
13.
Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families
Beverley Wilson, Chloe Flett, Jakub Gemperle, Craig Lawless, Matthew Hartshorn, Eleanor Hinde, Tess Harrison, Megan Chastney, Sarah Taylor, Jennifer Allen, Jim C. Norman, Thomas Zacharchenko, Patrick T. Caswell
J Cell Sci. 2023 Jun 15; 136(12): jcs260468. Published online 2023 Jun 23. doi: 10.1242/jcs.260468
PMCID:
PMC10323252
AbstractArticle
14.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
15.
Fibril treatment changes protein interactions of tau and α-synuclein in human neurons
Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson
J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888
PMCID:
PMC9978635
AbstractArticlePDF–10M
16.
Long non-coding RNA SLC25A21-AS1 inhibits the development of epithelial ovarian cancer by specifically inducing PTBP3 degradation
Sihui Li, Shizhen Shen, Wanzhong Ge, Yixuan Cen, Songfa Zhang, Xiaodong Cheng, Xinyu Wang, Xing Xie, Weiguo Lu
Biomark Res. 2023; 11: 12. Published online 2023 Jan 30. doi: 10.1186/s40364-022-00432-x
Correction in:
Biomark Res. 2024; 12: 108.
PMCID:
PMC9885650
AbstractArticlePDF–11M
17.
CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1
Dongbao Li, Yuhong Wang, Chao Dong, Tao Chen, Anqi Dong, Jiayu Ren, Weikang Li, Gege Shu, Jiaoyang Yang, Wenhao Shen, Lei Qin, Lin Hu, Jin Zhou
Oncogene. 2023; 42(2): 83–98. Published online 2022 Nov 12. doi: 10.1038/s41388-022-02537-x
PMCID:
PMC9816059
AbstractArticlePDF–7.6M
18.
Activation of NOTCH signaling via DLL1 is mediated by APE1-redox-dependent NF-κB activation in esophageal adenocarcinoma
Lei Chen, Heng Lu, Dunfa Peng, Longlong Cao, Farah Ballout, Kannappan Sriramajayam, Zheng Chen, Ajaz Bhat, Timothy C. Wang, Anthony Capobianco, Jianwen Que, Oliver G McDonald, Alexander Zaika, Shutian Zhang, Wael El-Rifai
Gut. Author manuscript; available in PMC 2024 Mar 1.
Published in final edited form as: Gut. 2023 Mar; 72(3): 421–432. Published online 2022 Jun 24. doi: 10.1136/gutjnl-2022-327076
PMCID:
PMC9789198
AbstractArticlePDF–2.8M
19.
The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers
Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy
eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676
PMCID:
PMC9708086
AbstractArticlePDF–8.5M
20.
APEX1 promotes the oncogenicity of hepatocellular carcinoma via regulation of MAP2K6
Zhipeng Sun, Guangyang Chen, Liang Wang, Qing Sang, Guangzhong Xu, Nengwei Zhang
Aging (Albany NY) 2022 Oct 15; 14(19): 7959–7971. Published online 2022 Oct 4. doi: 10.18632/aging.204325
PMCID:
PMC9596212
AbstractArticlePDF–1.2M

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