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Items: 1 to 20 of 37

1.
Netrins and netrin receptorsRID="†"ID="†" Review
F. J. Livesey
Cell Mol Life Sci. 1999 Oct; 56(1-2): 62–68. doi: 10.1007/s000180050006
PMCID:
PMC11146895
AbstractArticlePDF–70K
2.
UNC5C: Novel Gene Associated with Psychiatric Disorders Impacts Dysregulation of Axon Guidance Pathways
Simone Treccarichi, Pinella Failla, Mirella Vinci, Antonino Musumeci, Angelo Gloria, Anna Vasta, Giuseppe Calabrese, Carla Papa, Concetta Federico, Salvatore Saccone, Francesco Calì
Genes (Basel) 2024 Mar; 15(3): 306. Published online 2024 Feb 27. doi: 10.3390/genes15030306
PMCID:
PMC10970690
AbstractArticlePDF–2.7M
3.
A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2–Bispecific Antibody for Combination Cancer Therapy
Amr El Zawily, Frederick S. Vizeacoumar, Renuka Dahiya, Sara L. Banerjee, Kalpana K. Bhanumathy, Hussain Elhasasna, Glinton Hanover, Jessica C. Sharpe, Malkon G. Sanchez, Paul Greidanus, R. Greg Stacey, Kyung-Mee Moon, Ilya Alexandrov, Juha P. Himanen, Dimitar B. Nikolov, Humphrey Fonge, Aaron P. White, Leonard J. Foster, Bingcheng Wang, Behzad M. Toosi, Nicolas Bisson, Tajib A. Mirzabekov, Franco J. Vizeacoumar, Andrew Freywald
Clin Cancer Res. 2023 Jul 14; 29(14): 2686–2701. Published online 2023 Mar 28. doi: 10.1158/1078-0432.CCR-22-2535
PMCID:
PMC10345963
AbstractArticlePDF–13M
4.
Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB
Fu‐Long Li, Zhengming Wu, Yong‐Qi Gao, Forrest Z Bowling, J Matthew Franklin, Chongze Hu, Raymond T Suhandynata, Michael A Frohman, Michael V Airola, Huilin Zhou, Kun‐Liang Guan
EMBO J. 2022 Sep; 41(17): e110698. Published online 2022 Jul 17. doi: 10.15252/embj.2022110698
PMCID:
PMC9433938
AbstractArticlePDF–9.3M
5.
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery
Xiaonan Liu, Sini Huuskonen, Tuomo Laitinen, Taras Redchuk, Mariia Bogacheva, Kari Salokas, Ina Pöhner, Tiina Öhman, Arun Kumar Tonduru, Antti Hassinen, Lisa Gawriyski, Salla Keskitalo, Maria K Vartiainen, Vilja Pietiäinen, Antti Poso, Markku Varjosalo
Mol Syst Biol. 2021 Nov; 17(11): e10396. Published online 2021 Oct 28. doi: 10.15252/msb.202110396
PMCID:
PMC8552907
AbstractArticlePDF–3.9M
6.
BioID reveals an ATG9A interaction with ATG13‐ATG101 in the degradation of p62/SQSTM1‐ubiquitin clusters
Ashari R Kannangara, Daniel M Poole, Colten M McEwan, Joshua C Youngs, Vajira K Weerasekara, Alex M Thornock, Misael T Lazaro, Eranga R Balasooriya, Laura M Oh, Erik J Soderblom, Jonathan J Lee, Daniel L Simmons, Joshua L Andersen
EMBO Rep. 2021 Oct 5; 22(10): e51136. Published online 2021 Aug 9. doi: 10.15252/embr.202051136
PMCID:
PMC8490997
AbstractArticlePDF–4.5M
7.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
8.
PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential
Leena Yadav, Elina Pietilä, Tiina Öhman, Xiaonan Liu, Arun K. Mahato, Yulia Sidorova, Kaisa Lehti, Mart Saarma, Markku Varjosalo
iScience. 2020 Feb 21; 23(2): 100871. Published online 2020 Jan 31. doi: 10.1016/j.isci.2020.100871
PMCID:
PMC7021549
AbstractArticlePDF–8.1M
9.
UNC5C-knockdown enhances the growth and metastasis of breast cancer cells by potentiating the integrin α6/β4 signaling pathway
Mingjing Yuan, Fuan Xie, Xianyuan Xia, Kai Zhong, Lanlan Lian, Shihui Zhang, Li Yuan, Jun Ye
Int J Oncol. 2020 Jan; 56(1): 139–150. Published online 2019 Dec 2. doi: 10.3892/ijo.2019.4931
PMCID:
PMC6910211
AbstractArticlePDF–1.7M
10.
Mapping Netrin Receptor Binding Reveals Domains of Unc5 Regulating Its Tyrosine Phosphorylation
Robert P. Kruger, Jeeyong Lee, Weiquan Li, Kun-Liang Guan
J Neurosci. 2004 Dec 1; 24(48): 10826–10834. doi: 10.1523/JNEUROSCI.3715-04.2004
PMCID:
PMC6730211
AbstractArticlePDF–697K
11.
TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile
Karen Dendoncker, Steven Timmermans, Jolien Vandewalle, Melanie Eggermont, Joanna Lempiäinen, Evelien Van Hamme, Sylviane Dewaele, Sofie Vandevyver, Marlies Ballegeer, Jolien Souffriau, Lise Van Wyngene, Kelly Van Looveren, Tineke Vanderhaeghen, Rudi Beyaert, Karolien De Bosscher, Jorma J. Palvimo, Marc Van Montagu, Claude Libert
Proc Natl Acad Sci U S A. 2019 Jun 25; 116(26): 12942–12951. Published online 2019 Jun 10. doi: 10.1073/pnas.1821565116
Correction in:
Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15745.
PMCID:
PMC6600915
AbstractArticlePDF–1.7M
12.
An UNC5C Allele Predicts Cognitive Decline and Hippocampal Atrophy in Clinically Normal Older Adults
Hyun-Sik Yang, Jasmeer P. Chhatwal, Jishu Xu, Charles C. White, Bernard Hanseeuw, Jennifer S. Rabin, Kathryn V. Papp, Rachel F. Buckley, Aaron P. Schultz, Michael J. Properzi, Jennifer R. Gatchel, Rebecca E. Amariglio, Nancy J. Donovan, Elizabeth C. Mormino, Trey Hedden, Gad A. Marshall, Dorene M. Rentz, Keith A. Johnson, Philip L. De Jager, Reisa A. Sperling
J Alzheimers Dis. Author manuscript; available in PMC 2019 Jun 16.
Published in final edited form as: J Alzheimers Dis. 2019; 68(3): 1161–1170. doi: 10.3233/JAD-180788
PMCID:
PMC6571137
AbstractArticlePDF–450K
13.
Significant Pattern of Promoter Hypermethylation of UNC5C Gene in Colorectal Cancer and Its Implication in Late Stage Disease
Sartaj A Guroo, Ajaz A Malik, Dil Afroze, Shazia Ali, Arshad A Pandith, Adfar Yusuf
Asian Pac J Cancer Prev. 2018; 19(5): 1185–1188. doi: 10.22034/APJCP.2018.19.5.1185
PMCID:
PMC6031814
AbstractArticlePDF–286K
14.
Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism
Giulia Antoniali, Fabrizio Serra, Lisa Lirussi, Mikiei Tanaka, Chiara D’Ambrosio, Shiheng Zhang, Slobodanka Radovic, Emiliano Dalla, Yari Ciani, Andrea Scaloni, Mengxia Li, Silvano Piazza, Gianluca Tell
Nat Commun. 2017; 8: 797. Published online 2017 Oct 6. doi: 10.1038/s41467-017-00842-8
PMCID:
PMC5630600
AbstractArticlePDF–2.3M
15.
Uncoupling of UNC5C with Polymerized TUBB3 in Microtubules Mediates Netrin-1 Repulsion
Qiangqiang Shao, Tao Yang, Huai Huang, Farrah Alarmanazi, Guofa Liu
J Neurosci. 2017 Jun 7; 37(23): 5620–5633. doi: 10.1523/JNEUROSCI.2617-16.2017
PMCID:
PMC5469302
AbstractArticlePDF–4.7M
16.
Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data
Charles C. White, Hyun-Sik Yang, Lei Yu, Lori B. Chibnik, Robert J. Dawe, Jingyun Yang, Hans-Ulrich Klein, Daniel Felsky, Alfredo Ramos-Miguel, Konstantinos Arfanakis, William G. Honer, Reisa A. Sperling, Julie A. Schneider, David A. Bennett, Philip L. De Jager
PLoS Med. 2017 Apr; 14(4): e1002287. Published online 2017 Apr 25. doi: 10.1371/journal.pmed.1002287
PMCID:
PMC5404753
AbstractArticlePDF–2.2M
17.
A dynamic protein interaction landscape of the human centrosome-cilium interface
Gagan D. Gupta, Étienne Coyaud, João Gonçalves, Bahareh A. Mojarad, Yi Liu, Qianzhu Wu, Ladan Gheiratmand, David Comartin, Johnny M. Tkach, Sally W.T. Cheung, Mikhail Bashkurov, Monica Hasegan, James D. Knight, Zhen-Yuan Lin, Markus Schueler, Friedhelm Hildebrandt, Jason Moffat, Anne-Claude Gingras, Brian Raught, Laurence Pelletier
Cell. Author manuscript; available in PMC 2016 Dec 3.
Published in final edited form as: Cell. 2015 Dec 3; 163(6): 1484–1499. doi: 10.1016/j.cell.2015.10.065
PMCID:
PMC5089374
AbstractArticlePDF–1.5M
18.
An Alzheimer Disease-linked Rare Mutation Potentiates Netrin Receptor Uncoordinated-5C-induced Signaling That Merges with Amyloid β Precursor Protein Signaling
Yuichi Hashimoto, Yuka Toyama, Shinya Kusakari, Mikiro Nawa, Masaaki Matsuoka
J Biol Chem. 2016 Jun 3; 291(23): 12282–12293. Published online 2016 Apr 11. doi: 10.1074/jbc.M115.698092
PMCID:
PMC4933276
AbstractArticlePDF–2.1M
19.
Scarce evidence of the causal role of germline mutations in UNC5C in hereditary colorectal cancer and polyposis
Pilar Mur, Sánchez-Cuartielles Elena, Susanna Aussó, Gemma Aiza, Valdés-Mas Rafael, Marta Pineda, Matilde Navarro, Joan Brunet, Miguel Urioste, Conxi Lázaro, Victor Moreno, Gabriel Capellá, Xose S. Puente, Laura Valle
Sci Rep. 2016; 6: 20697. Published online 2016 Feb 8. doi: 10.1038/srep20697
Correction in:
Sci Rep. 2016; 6: 23880.
PMCID:
PMC4745060
AbstractArticlePDF–633K
20.
Non-Replication of Association for Six Polymorphisms From Meta-Analysis of Genome-Wide Association Studies of Parkinson’s Disease: Large-Scale Collaborative Study
Evangelos Evangelou, Demetrius M. Maraganore, Grazia Annesi, Laura Brighina, Alexis Brice, Alexis Elbaz, Carlo Ferrarese, Georgios M. Hadjigeorgiou, Rejko Krueger, Jean-Charles Lambert, Suzanne Lesage, Katerina Markopoulou, George D. Mellick, Bram Meeus, Nancy L. Pedersen, Aldo Quattrone, Christine Van Broeckhoven, Manu Sharma, Peter A. Silburn, Eng-King Tan, Karin Wirdefeldt, John P.A. Ioannidis
Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2016 Jan 4.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 5; 0(1): 220–228. doi: 10.1002/ajmg.b.30980
PMCID:
PMC4699803
AbstractArticlePDF–351K

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