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Select item 109168351.

Genetic diagnosis of congenital hypopituitarism in Turkish patients by a target gene panel: novel pathogenic variants in GHRHR, GLI2, LHX4 and POU1F1 genes

Tarık Kırkgöz, Semra Gürsoy, Sezer Acar, Özlem Nalbantoğlu, Beyhan Özkaya, Hüseyin Anıl Korkmaz, Filiz Hazan, Behzat Özkan

Arch Endocrinol Metab. 2024; 68: e220254. Published online 2023 Nov 10. doi: 10.20945/2359-4292-2022-0254

PMCID:: PMC10916835

Abstract Article PDF–193K

Select item 103558882.

Expression of Receptors for Pituitary-Type Growth Hormone-Releasing Hormone (pGHRH-R) in Human Papillary Thyroid Cancer Cells: Effects of GHRH Antagonists on Matrix Metalloproteinase-2

Paola Catanuto, Jun Tashiro, Ferenc G. Rick, Patricia Sanchez, Carmen C. Solorzano, Marilyn K. Glassberg, Norman L. Block, John I. Lew, Sharon J. Elliot, Andrew V. Schally

Horm Cancer. 2015 Jun; 6(2-3): 100–106. Published online 2015 Mar 10. doi: 10.1007/s12672-015-0217-2

PMCID:: PMC10355888

Abstract Article PDF–882K

Select item 91013863.

Expression of Growth Hormone-Releasing Hormone and Its Receptor Splice Variants in Primary Human Endometrial Carcinomas: Novel Therapeutic Approaches

Zsuzsanna Szabo, Eva Juhasz, Andrew V. Schally, Balazs Dezso, Sandor Huga, Zoltan Hernadi, Gabor Halmos, Csongor Kiss

Molecules. 2022 May; 27(9): 2671. Published online 2022 Apr 21. doi: 10.3390/molecules27092671

PMCID:: PMC9101386

Abstract Article PDF–738K

Select item 85017994.

Constitutive signal bias mediated by the human GHRHR splice variant 1

Zhaotong Cong, Fulai Zhou, Chao Zhang, Xinyu Zou, Huibing Zhang, Yuzhe Wang, Qingtong Zhou, Xiaoqing Cai, Qiaofeng Liu, Jie Li, Lijun Shao, Chunyou Mao, Xi Wang, Jihong Wu, Tian Xia, Li-Hua Zhao, Hualiang Jiang, Yan Zhang, H. Eric Xu, Xi Cheng, Dehua Yang, Ming-Wei Wang

Proc Natl Acad Sci U S A. 2021 Oct 5; 118(40): e2106606118. Published online 2021 Oct 1. doi: 10.1073/pnas.2106606118

PMCID:: PMC8501799

Abstract Article PDF–2.1M

Select item 75671035.

Structural basis for activation of the growth hormone-releasing hormone receptor

Fulai Zhou, Huibing Zhang, Zhaotong Cong, Li-Hua Zhao, Qingtong Zhou, Chunyou Mao, Xi Cheng, Dan-Dan Shen, Xiaoqing Cai, Cheng Ma, Yuzhe Wang, Antao Dai, Yan Zhou, Wen Sun, Fenghui Zhao, Suwen Zhao, Hualiang Jiang, Yi Jiang, Dehua Yang, H. Eric Xu, Yan Zhang, Ming-Wei Wang

Nat Commun. 2020; 11: 5205. Published online 2020 Oct 15. doi: 10.1038/s41467-020-18945-0

PMCID:: PMC7567103

Abstract Article PDF–3.1M

Select item 70840746.

Signaling mechanisms of growth hormone-releasing hormone receptor in LPS-induced acute ocular inflammation

Wei Cheng Liang, Jia Lin Ren, Qiu Xiao Yu, Jian Li, Tsz Kin Ng, Wai Kit Chu, Yong Jie Qin, Kai On Chu, Andrew V. Schally, Chi Pui Pang, Sun On Chan

Proc Natl Acad Sci U S A. 2020 Mar 17; 117(11): 6067–6074. Published online 2020 Mar 2. doi: 10.1073/pnas.1904532117

PMCID:: PMC7084074

Abstract Article PDF–1.4M

Select item 60395017.

CUEDC2, a novel interacting partner of the SOCS1 protein, plays important roles in the leukaemogenesis of acute myeloid leukaemia

Qing-Yun Wu, Yuan-Yuan Zhu, Yang Liu, Fang Wei, Yu-Xue Tong, Jiang Cao, Ping Zhou, Ming-Shan Niu, Zhen-Yu Li, Ling-Yu Zeng, Feng Li, Kai-Lin Xu

Cell Death Dis. 2018 Jul; 9(7): 774. Published online 2018 Jul 10. doi: 10.1038/s41419-018-0812-6

PMCID:: PMC6039501

Abstract Article PDF–2.7M

Select item 42936548.

Novel Growth Hormone-Releasing Hormone Receptor Gene Mutations in Turkish Children with Isolated Growth Hormone Deficiency

Ahmet Arman, Bumin Nuri Dündar, Ergun Çetinkaya, Nilüfer Erzaim, Atilla Büyükgebiz

J Clin Res Pediatr Endocrinol. 2014 Dec; 6(4): 202–208. Published online 2014 Dec 5. doi: 10.4274/jcrpe.1518

PMCID:: PMC4293654

Abstract Article PDF–296K

Select item 32723089.

The Consequences of GHRH-R Haplo-Insufficiency for Bone Quality and Insulin resistance

Miburge B. Gois-Jr, Roberto Salvatori, Manuel H. Aguiar-Oliveira, Francisco A. Pereira, Carla R. P. Oliveira, Luiz A. Oliveira-Neto, Rossana M. C. Pereira, Anita H.O. Souza, Enaldo V. Melo, Francisco J. A. de Paula

Clin Endocrinol (Oxf) Author manuscript; available in PMC 2013 Sep 1.

Published in final edited form as: Clin Endocrinol (Oxf). 2012 Sep; 77(3): 379–384. doi: 10.1111/j.1365-2265.2011.04263.x

PMCID:: PMC3272308

Abstract Article PDF–581K

Select item 317805910.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 310558711.

Xiaofan Zhang, Hushan Yang, J.Jack Lee, Edward Kim, Scott M. Lippman, Fadlo R. Khuri, Margaret R. Spitz, Reuben Lotan, Waun K. Hong, Xifeng Wu

Carcinogenesis. 2010 Dec; 31(12): 2118–2123. Published online 2010 Sep 5. doi: 10.1093/carcin/bgq177

PMCID:: PMC3105587

Abstract Article PDF–236K

Select item 298940412.

Eighteen Insulin-like Growth Factor (IGF) pathway genes, circulating levels of IGF-1 and its binding protein (IGFBP-3), and risk of prostate and breast cancer

Fangyi Gu, Fredrick R. Schumacher, Federico Canzian, Naomi E. Allen, Demetrius Albanes, Christine D Berg, Sonja I. Berndt, Heiner Boeing, H. Bas Bueno-de-Mesquita, Julie E. Buring, Nathalie Chabbert-Buffet, Stephen J. Chanock, Françoise Clavel-Chapelon, Vanessa Dumeaux, J. Michael Gaziano, Edward L. Giovannucci, Christopher A. Haiman, Susan E. Hankinson, Richard B. Hayes, Brian E. Henderson, David J. Hunter, Robert N. Hoover, Mattias Johansson, Timothy J. Key, Kay-Tee Khaw, Laurence N. Kolonel, Pagona Lagiou, I-Min Lee, Loic LeMarchand, Eiliv Lund, Jing Ma, N. Charlotte Onland-Moret, Kim Overvad, Laudina Rodriguez, Carlotta Sacerdote, Maria-José Sánchez, Meir J. Stampfer, Pär Stattin, Daniel O. Stram, Gilles Thomas, Michael J. Thun, Anne Tjønneland, Dimitrios Trichopoulos, Rosario Tumino, Jarmo Virtamo, Stephanie J. Weinstein, Walter C. Willett, Meredith Yeager, Shumin M. Zhang, Rudolf Kaaks, Elio Riboli, Regina G. Ziegler, Peter Kraft

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2011 Nov 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2010 Nov; 19(11): 2877–2887. Published online 2010 Sep 1. doi: 10.1158/1055-9965.EPI-10-0507

PMCID:: PMC2989404

Abstract Article PDF–108K

Select item 296729713.

A large-scale candidate-gene association study of age at menarche and age at natural menopause

Chunyan He, Peter Kraft, Daniel I. Chasman, Julie E. Buring, Constance Chen, Susan E. Hankinson, Guillaume Paré, Stephen Chanock, Paul M. Ridker, David J. Hunter

Hum Genet. Author manuscript; available in PMC 2010 Nov 1.

Published in final edited form as: Hum Genet. 2010 Nov; 128(5): 515–527. Published online 2010 Aug 24. doi: 10.1007/s00439-010-0878-4

PMCID:: PMC2967297

Abstract Article PDF–84K

Select item 294516814.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

Select item 293585615.

Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium

Federico Canzian, David G. Cox, V. Wendy Setiawan, Daniel O. Stram, Regina G. Ziegler, Laure Dossus, Lars Beckmann, Hélène Blanché, Aurelio Barricarte, Christine D. Berg, Sheila Bingham, Julie Buring, Saundra S. Buys, Eugenia E. Calle, Stephen J. Chanock, Françoise Clavel-Chapelon, John Oliver L. DeLancey, W. Ryan Diver, Miren Dorronsoro, Christopher A. Haiman, Göran Hallmans, Susan E. Hankinson, David J. Hunter, Anika Hüsing, Claudine Isaacs, Kay-Tee Khaw, Laurence N. Kolonel, Peter Kraft, Loïc Le Marchand, Eiliv Lund, Kim Overvad, Salvatore Panico, Petra H.M. Peeters, Michael Pollak, Michael J. Thun, Anne Tjønneland, Dimitrios Trichopoulos, Rosario Tumino, Meredith Yeager, Robert N. Hoover, Elio Riboli, Gilles Thomas, Brian E. Henderson, Rudolf Kaaks, Heather Spencer Feigelson

Hum Mol Genet. 2010 Oct 1; 19(19): 3873–3884. Published online 2010 Jul 15. doi: 10.1093/hmg/ddq291

PMCID:: PMC2935856

Abstract Article PDF–274K

Select item 289380016.

A Large-scale genetic association study of esophageal adenocarcinoma risk

Chen-yu Liu, Michael C. Wu, Feng Chen, Monica Ter-Minassian, Kofi Asomaning, Rihong Zhai, Zhaoxi Wang, Li Su, Rebecca S. Heist, Matthew H. Kulke, Xihong Lin, Geoffrey Liu, David C. Christiani

Carcinogenesis. 2010 Jul; 31(7): 1259–1263. Published online 2010 May 7. doi: 10.1093/carcin/bgq092

PMCID:: PMC2893800

Abstract Article PDF–84K

Select item 288296117.

Human Chromosome 7: DNA Sequence and Biology

Stephen W. Scherer, Joseph Cheung, Jeffrey R. MacDonald, Lucy R. Osborne, Kazuhiko Nakabayashi, Jo-Anne Herbrick, Andrew R. Carson, Layla Parker-Katiraee, Jennifer Skaug, Razi Khaja, Junjun Zhang, Alexander K. Hudek, Martin Li, May Haddad, Gavin E. Duggan, Bridget A. Fernandez, Emiko Kanematsu, Simone Gentles, Constantine C. Christopoulos, Sanaa Choufani, Dorota Kwasnicka, Xiangqun H. Zheng, Zhongwu Lai, Deborah Nusskern, Qing Zhang, Zhiping Gu, Fu Lu, Susan Zeesman, Malgorzata J. Nowaczyk, Ikuko Teshima, David Chitayat, Cheryl Shuman, Rosanna Weksberg, Elaine H. Zackai, Theresa A. Grebe, Sarah R. Cox, Susan J. Kirkpatrick, Nazneen Rahman, Jan M. Friedman, Henry H. Q. Heng, Pier Giuseppe Pelicci, Francesco Lo-Coco, Elena Belloni, Lisa G. Shaffer, Barbara Pober, Cynthia C. Morton, James F. Gusella, Gail A. P. Bruns, Bruce R. Korf, Bradley J. Quade, Azra H. Ligon, Heather Ferguson, Anne W. Higgins, Natalia T. Leach, Steven R. Herrick, Emmanuelle Lemyre, Chantal G. Farra, Hyung-Goo Kim, Anne M. Summers, Karen W. Gripp, Wendy Roberts, Peter Szatmari, Elizabeth J. T. Winsor, Karl-Heinz Grzeschik, Ahmed Teebi, Berge A. Minassian, Juha Kere, Lluis Armengol, Miguel Angel Pujana, Xavier Estivill, Michael D. Wilson, Ben F. Koop, Sabrina Tosi, Gudrun E. Moore, Andrew P. Boright, Eitan Zlotorynski, Batsheva Kerem, Peter M. Kroisel, Erwin Petek, David G. Oscier, Sarah J. Mould, Hartmut Döhner, Konstanze Döhner, Johanna M. Rommens, John B. Vincent, J. Craig Venter, Peter W. Li, Richard J. Mural, Mark D. Adams, Lap-Chee Tsui

Science. Author manuscript; available in PMC 2010 Jun 9.

Published in final edited form as: Science. 2003 May 2; 300(5620): 767–772. Published online 2003 Apr 10. doi: 10.1126/science.1083423

PMCID:: PMC2882961

Abstract Article PDF–1.2M

Select item 284087018.

Longevity in Untreated Congenital Growth Hormone Deficiency Due to a Homozygous Mutation in the GHRH Receptor Gene

Manuel H. Aguiar-Oliveira, Francielle T. Oliveira, Rossana M. C. Pereira, Carla R. P. Oliveira, Amanda Blackford, Eugenia H. O. Valenca, Elenilde G. Santos, Miburge B. Gois-Junior, Rafael A. Meneguz-Moreno, Vanessa P. Araujo, Luis A. Oliveira-Neto, Roque P. Almeida, Mário A. Santos, Natalia T. Farias, Debora C. R. Silveira, Gabriel W. Cabral, Flavia R. Calazans, Juliane D. Seabra, Tiago F. Lopes, Endrigo O. Rodrigues, Livia A. Porto, Igor P. Oliveira, Enaldo V. Melo, Marco Martari, Roberto Salvatori

J Clin Endocrinol Metab. 2010 Feb; 95(2): 714–721. Published online 2009 Dec 4. doi: 10.1210/jc.2009-1879

PMCID:: PMC2840870

Abstract Article

Select item 279151819.

High-Density Association Study of 383 Candidate Genes for Volumetric BMD at the Femoral Neck and Lumbar Spine Among Older Men

Laura M. Yerges, Lambertus Klei, Jane A. Cauley, Kathryn Roeder, Candace M. Kammerer, Susan P. Moffett, Kristine E. Ensrud, Cara S. Nestlerode, Lynn M. Marshall, Andrew R. Hoffman, Cora Lewis, Thomas F. Lang, Elizabeth Barrett-Connor, Robert E. Ferrell, Eric S. Orwoll, Joseph M. Zmuda

J Bone Miner Res. 2009 Dec; 24(12): 2039–2049. Published online 2009 May 18. doi: 10.1359/JBMR.090524

PMCID:: PMC2791518

Abstract Article PDF–759K

Select item 277583220.

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani

Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014