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Items: 1 to 20 of 29

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Sleeve Gastrectomy Improves Hepatic Glucose Metabolism by Downregulating FBXO2 and Activating the PI3K-AKT Pathway
Ningyuan Chen, Ruican Cao, Zhao Zhang, Sai Zhou, Sanyuan Hu
Int J Mol Sci. 2023 Mar; 24(6): 5544. Published online 2023 Mar 14. doi: 10.3390/ijms24065544
PMCID:
PMC10052132
AbstractArticlePDF–6.9M
3.
Fbxo2CreERT2: A new model for targeting cells in the neonatal and mature inner ear
Melissa M. McGovern, Byron Hartman, Ankita Thawani, Helen Maunsell, Hongyuan Zhang, Rizwan Yousaf, Stefan Heller, Jennifer Stone, Andrew K. Groves
Hear Res. Author manuscript; available in PMC 2024 Feb 1.
Published in final edited form as: Hear Res. 2023 Feb; 428: 108686. Published online 2022 Dec 27. doi: 10.1016/j.heares.2022.108686
PMCID:
PMC9840692
AbstractArticlePDF–1.8M
4.
Loss of peptide:N-glycanase causes proteasome dysfunction mediated by a sugar-recognizing ubiquitin ligase
Yukiko Yoshida, Makoto Asahina, Arisa Murakami, Junko Kawawaki, Meari Yoshida, Reiko Fujinawa, Kazuhiro Iwai, Ryuichi Tozawa, Noriyuki Matsuda, Keiji Tanaka, Tadashi Suzuki
Proc Natl Acad Sci U S A. 2021 Jul 6; 118(27): e2102902118. Published online 2021 Jul 2. doi: 10.1073/pnas.2102902118
PMCID:
PMC8271764
AbstractArticlePDF–1.6M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
Selective Cochlear Degeneration in Mice Lacking the F-Box Protein, Fbx2, a Glycoprotein-Specific Ubiquitin Ligase Subunit
Rick F. Nelson, Kevin A. Glenn, Yuzhou Zhang, Hsiang Wen, Tina Knutson, Cynthia M. Gouvion, Barbara K. Robinson, Zouping Zhou, Baoli Yang, Richard J. H. Smith, Henry L. Paulson
J Neurosci. 2007 May 9; 27(19): 5163–5171. doi: 10.1523/JNEUROSCI.0206-07.2007
PMCID:
PMC6672365
AbstractArticlePDF–467K
7.
Fbxo2VHC mouse and embryonic stem cell reporter lines delineate in vitro-generated inner ear sensory epithelia cells and enable otic lineage selection and Cre-recombination
Byron H. Hartman, Robert Böscke, Daniel C. Ellwanger, Sawa Keymeulen, Mirko Scheibinger, Stefan Heller
Dev Biol. Author manuscript; available in PMC 2019 Nov 1.
Published in final edited form as: Dev Biol. 2018 Nov 1; 443(1): 64–77. Published online 2018 Sep 1. doi: 10.1016/j.ydbio.2018.08.013
PMCID:
PMC6415763
AbstractArticlePDF–5.0M
8.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
9.
Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling
Brent Wilkinson, Jing Li, Marcelo P. Coba
Sci Rep. 2017; 7: 5272. Published online 2017 Jul 13. doi: 10.1038/s41598-017-05588-3
PMCID:
PMC5509740
AbstractArticlePDF–4.6M
10.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
11.
Structural analysis of a function-associated loop mutant of the substrate-recognition domain of Fbs1 ubiquitin ligase
Kazuya Nishio, Yukiko Yoshida, Keiji Tanaka, Tsunehiro Mizushima
Acta Crystallogr F Struct Biol Commun. 2016 Aug 1; 72(Pt 8): 619–626. Published online 2016 Jul 27. doi: 10.1107/S2053230X16011018
PMCID:
PMC4973303
AbstractArticlePDF–2.1M
12.
FBG1 Is the Final Arbitrator of A1AT-Z Degradation
John H. Wen, Hsiang Wen, Katherine N. Gibson-Corley, Kevin A. Glenn
PLoS One. 2015; 10(8): e0135591. Published online 2015 Aug 21. doi: 10.1371/journal.pone.0135591
PMCID:
PMC4546667
AbstractArticlePDF–1.9M
13.
Loss of F-box Only Protein 2 (Fbxo2) Disrupts Levels and Localization of Select NMDA Receptor Subunits, and Promotes Aberrant Synaptic Connectivity
Graham Atkin, Shannon Moore, Yuan Lu, Rick F. Nelson, Nathan Tipper, Gautam Rajpal, Jack Hunt, William Tennant, Johannes W. Hell, Geoffrey G. Murphy, Henry Paulson
J Neurosci. 2015 Apr 15; 35(15): 6165–6178. doi: 10.1523/JNEUROSCI.3013-14.2015
PMCID:
PMC4397610
AbstractArticlePDF–3.5M
14.
F-box Only Protein 2 (Fbxo2) Regulates Amyloid Precursor Protein Levels and Processing
Graham Atkin, Jack Hunt, Eiko Minakawa, Lisa Sharkey, Nathan Tipper, William Tennant, Henry L. Paulson
J Biol Chem. 2014 Mar 7; 289(10): 7038–7048. Published online 2014 Jan 27. doi: 10.1074/jbc.M113.515056
PMCID:
PMC3945364
AbstractArticlePDF–3.6M
15.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
16.
The ubiquitin ligase FBG1 promotes the degradation of the disease-linked protein torsinA through the ubiquitin proteasome pathway and macroautophagy
Kara L Gordon, Kevin A Glenn, Nicole Bode, Hsiang M Wen, Henry L Paulson, Pedro Gonzalez-Alegre
Neuroscience. Author manuscript; available in PMC 2013 Nov 8.
Published in final edited form as: Neuroscience. 2012 Nov 8; 224: 160–171. Published online 2012 Aug 20. doi: 10.1016/j.neuroscience.2012.08.023
PMCID:
PMC3475648
AbstractArticlePDF–1.0M
17.
Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain
Dyna I. Shirasaki, Erin R. Greiner, Ismael Al-Ramahi, Michelle Gray, Pinmanee Boontheung, Daniel H. Geschwind, Juan Botas, Giovanni Coppola, Steve Horvath, Joseph A. Loo, X. William Yang
Neuron. Author manuscript; available in PMC 2013 Jul 12.
Published in final edited form as: Neuron. 2012 Jul 12; 75(1): 41–57. doi: 10.1016/j.neuron.2012.05.024
PMCID:
PMC3432264
AbstractArticlePDF–4.9M
18.
SCFFbx2-E3-ligase-mediated degradation of BACE1 attenuates Alzheimer’s disease amyloidosis and improves synaptic function
Bing Gong, Fei Chen, Yong Pan, Isabel Arrieta-Cruz, Yukiko Yoshida, Vahram Haroutunian, Giulio M. Pasinetti
Aging Cell. Author manuscript; available in PMC 2012 Mar 19.
Published in final edited form as: Aging Cell. 2010 Dec; 9(6): 1018–1031. Published online 2010 Oct 29. doi: 10.1111/j.1474-9726.2010.00632.x
PMCID:
PMC3307224
AbstractArticlePDF–2.0M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
Genetic Variations Strongly Influence Phenotypic Outcome in the Mouse Retina
Austin S. Jelcick, Yang Yuan, Barrett D. Leehy, Lakeisha C. Cox, Alexandra C. Silveira, Fang Qiu, Sarah Schenk, Andrew J. Sachs, Margaux A. Morrison, Arne M. Nystuen, Margaret M. DeAngelis, Neena B. Haider
PLoS One. 2011; 6(7): e21858. Published online 2011 Jul 14. doi: 10.1371/journal.pone.0021858
Correction in:
PLoS One. 2011; 6(10): 10.1371/annotation/f375292d-9fc7-4e3c-9dc7-af0aee76fa15.
PMCID:
PMC3136482
AbstractArticlePDF–1.4M

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