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Items: 1 to 20 of 234

1.
Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy
Yan Guo, Pan Xiang, Xiaojiao Sun, Wei Liu, Jiafeng Zhou, Bin Yin, Lin Hou, Boqin Qiang, Huiliang Li, Pengcheng Shu, Xiaozhong Peng
Signal Transduct Target Ther. 2024; 9: 32. Published online 2024 Feb 14. doi: 10.1038/s41392-024-01742-2
PMCID:
PMC10864363
AbstractArticlePDF–9.9M
2.
Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development
Xiangyan Wang, Yan Zhang, Jianjie Yu, Yabo Ma, Yaxiu Xu, Jiaqi Shi, Zhipeng Qi, Xinfeng Liu
BMC Genomics. 2024; 25: 139. Published online 2024 Feb 3. doi: 10.1186/s12864-024-10058-y
PMCID:
PMC10837906
AbstractArticlePDF–7.1M
3.
Circ_MAPK9 promotes STAT3 and LDHA expression by silencing miR-642b-3p and affects the progression of hepatocellular carcinoma
Kunyuan Wang, Qianting Lu, Yufeng Luo, Ganxiang Yu, Zhilei Wang, Jiaen Lin, Zhenlin Tan, Yueqiong Lao, Shiming Liu, Hui Yang
Biol Direct. 2024; 19: 4. Published online 2024 Jan 2. doi: 10.1186/s13062-023-00442-1
PMCID:
PMC10759731
AbstractArticlePDF–7.6M
4.
Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibition
Vitor Ferreira, Cintia Folgueira, María García-Altares, Maria Guillén, Mónica Ruíz-Rosario, Giada DiNunzio, Irma Garcia-Martinez, Rosa Alen, Christoph Bookmeyer, John G. Jones, Juan C. Cigudosa, Pilar López-Larrubia, Xavier Correig-Blanchar, Roger J. Davis, Guadalupe Sabio, Patricia Rada, Ángela M. Valverde
Redox Biol. 2023 Jul; 63: 102741. Published online 2023 May 15. doi: 10.1016/j.redox.2023.102741
PMCID:
PMC10225935
AbstractArticlePDF–18M
5.
HER2-driven breast cancer suppression by the JNK signaling pathway
Zeynep Itah, Shanzah Chaudhry, Sithara Raju Ponny, Ozkan Aydemir, Alexandra Lee, Julie Cavanagh-Kyros, Cathy Tournier, William J. Muller, Roger J. Davis
Proc Natl Acad Sci U S A. 2023 Jan 24; 120(4): e2218373120. Published online 2023 Jan 19. doi: 10.1073/pnas.2218373120
PMCID:
PMC9942916
AbstractArticlePDF–5.9M
6.
Phosphorylation of RXRα mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome
Santiago Vernia, Alexandra Lee, Norman J. Kennedy, Myoung Sook Han, Marta Isasa, Julie Cavanagh-Kyros, Armanda Roy, Aafreen Syed, Shanzah Chaudhry, Yvonne J. K. Edwards, Steven P. Gygi, Guangping Gao, Roger J. Davis
Proc Natl Acad Sci U S A. 2022 Nov 1; 119(44): e2210434119. Published online 2022 Oct 25. doi: 10.1073/pnas.2210434119
PMCID:
PMC9636906
AbstractArticlePDF–1.7M
7.
EpCAM Is Essential to Maintaining the Immune Homeostasis of Intestines via Keeping the Expression of pIgR in the Intestinal Epithelium of Mice
Zili Lei, Wanwan Liu, Ya Nie, Yanhong Yang, Guibin Chen, Li Huang, Huijuan Wu, Yuting Lei, Lei Chen, Qing Hu, Hedong Rong, Siping Yu, Qi Song, Fengxue Tong, Jiao Guo
Front Immunol. 2022; 13: 843378. Published online 2022 Apr 13. doi: 10.3389/fimmu.2022.843378
PMCID:
PMC9043958
AbstractArticlePDF–8.1M
8.
Early construction of the thalamocortical axon pathway requires c-Jun N-terminal kinase signaling within the ventral forebrain
Jessica G. Cunningham, James D. Scripter, Stephany A. Nti, Eric S. Tucker
Dev Dyn. Author manuscript; available in PMC 2023 Mar 1.
Published in final edited form as: Dev Dyn. 2022 Mar; 251(3): 459–480. Published online 2021 Sep 18. doi: 10.1002/dvdy.416
PMCID:
PMC8891049
AbstractArticlePDF–2.5M
9.
miR-221-5p-Mediated Downregulation of JNK2 Aggravates Acute Lung Injury
Jing Yang, Hanh Chi Do-Umehara, Qiao Zhang, Huashan Wang, Changchun Hou, Huali Dong, Edith A. Perez, Marc A. Sala, Kishore R. Anekalla, James M. Walter, Shuwen Liu, Richard G. Wunderink, G.R. Scott Budinger, Jing Liu
Front Immunol. 2021; 12: 700933. Published online 2021 Nov 25. doi: 10.3389/fimmu.2021.700933
PMCID:
PMC8656235
AbstractArticlePDF–5.8M
10.
Mitogen Kinase Kinase (MKK7) Controls Cytokine Production In Vitro and In Vivo in Mice
Amada D. Caliz, Hyung-Jin Yoo, Anastassiia Vertii, Ana C. Dolan, Cathy Tournier, Roger J. Davis, John F. Keaney, Jr., Shashi Kant
Int J Mol Sci. 2021 Sep; 22(17): 9364. Published online 2021 Aug 29. doi: 10.3390/ijms22179364
PMCID:
PMC8431745
AbstractArticlePDF–1.9M
11.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
12.
Involvement of c-Jun N-terminal kinase 2 (JNK2) in Endothelin-1 (ET-1) Mediated Neurodegeneration of Retinal Ganglion Cells
Bindu Kodati, Dorota L. Stankowska, Vignesh R. Krishnamoorthy, Raghu R. Krishnamoorthy
Invest Ophthalmol Vis Sci. 2021 May; 62(6): 13. Published online 2021 May 12. doi: 10.1167/iovs.62.6.13
PMCID:
PMC8131991
AbstractArticlePDF–6.6M
13.
JNK signaling prevents biliary cyst formation through a CASPASE-8–dependent function of RIPK1 during aging
Katrin Müller, Hanna Honcharova-Biletska, Christiane Koppe, Michèle Egger, Lap Kwan Chan, Anne T. Schneider, Lena Küsgens, Friederike Böhm, Yannick Boege, Marc E. Healy, Johannes Schmitt, Sarah Comtesse, Mirco Castoldi, Christian Preisinger, Marta Szydlowska, Enrico Focaccia, Nadine T. Gaisa, Sven H. Loosen, Simone Jörs, Frank Tacke, Christoph Roderburg, Verena Keitel, Johannes G. Bode, Peter Boor, Roger J. Davis, Thomas Longerich, Fabian Geisler, Mathias Heikenwalder, Achim Weber, Mihael Vucur, Tom Luedde
Proc Natl Acad Sci U S A. 2021 Mar 23; 118(12): e2007194118. Published online 2021 Mar 8. doi: 10.1073/pnas.2007194118
PMCID:
PMC8000530
AbstractArticlePDF–3.0M
14.
Regulatory role of the TLR4/JNK signaling pathway in sepsis-induced myocardial dysfunction
Chao Chang, Liya Hu, Shanshan Sun, Yanqiu Song, Shan Liu, Jing Wang, Peijun Li
Mol Med Rep. 2021 May; 23(5): 334. Published online 2021 Mar 8. doi: 10.3892/mmr.2021.11973
PMCID:
PMC7974310
AbstractArticlePDF–870K
15.
Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS
Detian Yuan, Shan Huang, Emanuel Berger, Lei Liu, Nina Gross, Florian Heinzmann, Marc Ringelhan, Tracy O. Connor, Mira Stadler, Michael Meister, Julia Weber, Rupert Öllinger, Nicole Simonavicius, Florian Reisinger, Daniel Hartmann, Rüdiger Meyer, Maria Reich, Marco Seehawer, Valentina Leone, Bastian Höchst, Dirk Wohlleber, Simone Jörs, Marco Prinz, Duncan Spalding, Ulrike Protzer, Tom Luedde, Luigi Terracciano, Matthias Matter, Thomas Longerich, Percy Knolle, Thomas Ried, Verena Keitel, Fabian Geisler, Kristian Unger, Einat Cinnamon, Eli Pikarsky, Norbert Hüser, Roger J. Davis, Darjus F. Tschaharganeh, Roland Rad, Achim Weber, Lars Zender, Dirk Haller, Mathias Heikenwalder
Cancer Cell. Author manuscript; available in PMC 2021 Feb 26.
Published in final edited form as: Cancer Cell. 2017 Jun 12; 31(6): 771–789.e6. doi: 10.1016/j.ccell.2017.05.006
PMCID:
PMC7909318
AbstractArticlePDF–5.5M
16.
JNK2, A Newly-Identified SERCA2 Enhancer, Augments an Arrhythmic [Ca2+]SR Leak-Load Relationship
Jiajie Yan, Dan J Bare, Jaime DeSantiago, Weiwei Zhao, Yiming Mei, Zhenhui Chen, Kenneth Ginsburg, R John Solaro, Beata M Wolska, Donald M Bers, S.R. Wayne Chen, Xun Ai
Circ Res. Author manuscript; available in PMC 2022 Feb 19.
Published in final edited form as: Circ Res. 2021 Feb 19; 128(4): 455–470. Published online 2020 Dec 18. doi: 10.1161/CIRCRESAHA.120.318409
PMCID:
PMC7897290
AbstractArticlePDF–2.0M
17.
Secreted frizzled-related protein 5 (SFRP5) protects ATDC5 cells against LPS-induced inflammation and apoptosis via inhibiting Wnt5a/JNK pathway
Minghui Sun, Weijun Wang, Lingtian Min, Cheng Chen, Qing Li, Wenjie Weng
J Orthop Surg Res. 2021; 16: 129. Published online 2021 Feb 11. doi: 10.1186/s13018-021-02260-5
PMCID:
PMC7877043
AbstractArticlePDF–2.4M
18.
A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21
Myoung Sook Han, Rachel J. Perry, João-Paulo Camporez, Philipp E. Scherer, Gerald I. Shulman, Guangping Gao, Roger J. Davis
Genes Dev. 2021 Jan 1; 35(1-2): 133–146. doi: 10.1101/gad.344556.120
PMCID:
PMC7778269
AbstractArticlePDF–18M
19.
Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism
María Crespo, Barbara Gonzalez-Teran, Ivana Nikolic, Alfonso Mora, Cintia Folgueira, Elena Rodríguez, Luis Leiva-Vega, Aránzazu Pintor-Chocano, Macarena Fernández-Chacón, Irene Ruiz-Garrido, Beatriz Cicuéndez, Antonia Tomás-Loba, Noelia A-Gonzalez, Ainoa Caballero-Molano, Daniel Beiroa, Lourdes Hernández-Cosido, Jorge L Torres, Norman J Kennedy, Roger J Davis, Rui Benedito, Miguel Marcos, Ruben Nogueiras, Andrés Hidalgo, Nuria Matesanz, Magdalena Leiva, Guadalupe Sabio
eLife. 2020; 9: e59258. Published online 2020 Dec 8. doi: 10.7554/eLife.59258
PMCID:
PMC7723411
AbstractArticlePDF–4.2M
20.
Coiled-coil domain containing 50-V2 protein positively regulates neurite outgrowth
Ju-Sik Min, Debasish Halder, Ji-Yong Yoon, Su-Jin Jeon, Soo Young Jun, Jae-Ran Lee, Jeong-Ju Lee, Min-Hyuk Choi, Cho-Rok Jung, DaYong Lee, Byoung-Joon Kim, Nam-Soon Kim
Sci Rep. 2020; 10: 21295. Published online 2020 Dec 4. doi: 10.1038/s41598-020-78304-3
PMCID:
PMC7718278
AbstractArticlePDF–2.0M

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