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Items: 1 to 20 of 29

1.
TET1 and TDG suppress inflammatory response in intestinal tumorigenesis: implications for colorectal tumors with the CpG Island Methylator Phenotype
Rossella Tricarico, Jozef Madzo, Gabrielle Scher, Maya Cohen, Jaroslav Jelinek, Shinji Maegawa, Rajeswari Nagarathinam, Carly Scher, Wen-Chi Chang, Emmanuelle Nicolas, Michael Slifker, Yan Zhou, Karthik Devarajan, Kathy Q. Cai, Tim Kwok, Pamela Nakajima, Jinfei Xu, Pietro Mancuso, Valentina Doneddu, Luigi Bagella, Riley Williams, Siddharth Balachandran, Nicholas Maskalenko, Kerry Campbell, Xueying Ma, Israel Cañadas, Julen Viana, Victor Moreno, Laura Valle, Sergei Grivennikov, Iuliia Peshkova, Natalia Kurilenko, Aleksandra Mazitova, Ekaterina Koltsova, Hayan Lee, Martin Walsh, Reuben Duttweiler, Johnathan R. Whetstine, Timothy J. Yen, Jean-Pierre Issa, Alfonso Bellacosa
Gastroenterology. Author manuscript; available in PMC 2024 May 1.
Published in final edited form as: Gastroenterology. 2023 May; 164(6): 921–936.e1. Published online 2023 Feb 8. doi: 10.1053/j.gastro.2023.01.039
PMCID:
PMC10586516
AbstractArticlePDF–3.0M
2.
Roles of TET and TDG in DNA demethylation in proliferating and non-proliferating immune cells
Atsushi Onodera, Edahí González-Avalos, Chan-Wang Jerry Lio, Romain O. Georges, Alfonso Bellacosa, Toshinori Nakayama, Anjana Rao
Genome Biol. 2021; 22: 186. Published online 2021 Jun 22. doi: 10.1186/s13059-021-02384-1
PMCID:
PMC8218415
AbstractArticlePDF–3.4M
3.
Inducible TDG knockout models to study epigenetic regulation
Simon D. Schwarz, Eliane Grundbacher, Alexandra M. Hrovat, Jianming Xu, Anna Kuśnierczyk, Cathrine B. Vågbø, Primo Schär, David Schuermann
Version 2. F1000Res. 2020; 9: 1112. Published online 2020 Oct 19. doi: 10.12688/f1000research.25637.2
PMCID:
PMC7527862
AbstractArticlePDF–3.4M
4.
SUMOylation coordinates BERosome assembly in active DNA demethylation during cell differentiation
Roland Steinacher, Zeinab Barekati, Petar Botev, Anna Kuśnierczyk, Geir Slupphaug, Primo Schär
EMBO J. 2019 Jan 3; 38(1): e99242. Published online 2018 Dec 6. doi: 10.15252/embj.201899242
PMCID:
PMC6315294
AbstractArticlePDF–1.3M
5.
An intrinsic epigenetic barrier for functional axon regeneration
Yi-Lan Weng, Ran An, Jessica Cassin, Jessica Joseph, Ruifa Mi, Chen Wang, Chun Zhong, Seung-Gi Jin, Gerd P. Pfeifer, Alfonso Bellacosa, Xinzhong Dong, Ahmet Hoke, Zhigang He, Hongjun Song, Guo-li Ming
Neuron. Author manuscript; available in PMC 2018 Jun 19.
Published in final edited form as: Neuron. 2017 Apr 19; 94(2): 337–346.e6. doi: 10.1016/j.neuron.2017.03.034
PMCID:
PMC6007997
AbstractArticlePDF–2.5M
6.
Thymine DNA Glycosylase (TDG) is involved in the pathogenesis of intestinal tumors with reduced APC expression
Jinfei Xu, Salvatore Cortellino, Rossella Tricarico, Wen-Chi Chang, Gabrielle Scher, Karthik Devarajan, Michael Slifker, Robert Moore, Maria Rosaria Bassi, Elena Caretti, Margie Clapper, Harry Cooper, Alfonso Bellacosa
Oncotarget. 2017 Oct 27; 8(52): 89988–89997. Published online 2017 Sep 23. doi: 10.18632/oncotarget.21219
PMCID:
PMC5685726
AbstractArticlePDF–3.3M
7.
Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway
Petra Hajkova, Sean J. Jeffries, Caroline Lee, Nigel Miller, Stephen P. Jackson, M. Azim Surani
Science. Author manuscript; available in PMC 2013 Dec 16.
Published in final edited form as: Science. 2010 Jul 2; 329(5987): 10.1126/science.1187945. doi: 10.1126/science.1187945
PMCID:
PMC3863715
AbstractArticlePDF–2.1M
8.
Catalog of mRNA expression patterns for DNA methylating and demethylating genes in developing mouse lower urinary tract
Kimberly P. Keil, Helene M. Altmann, Vatsal Mehta, Lisa L. Abler, Erik A. Elton, Chad M. Vezina
Gene Expr Patterns. Author manuscript; available in PMC 2014 Dec 1.
Published in final edited form as: Gene Expr Patterns. 2013 Dec; 13(8): 10.1016/j.gep.2013.07.008. Published online 2013 Aug 3. doi: 10.1016/j.gep.2013.07.008
PMCID:
PMC3825751
AbstractArticlePDF–7.2M
9.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
10.
Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
Yu-Fei He, Bin-Zhong Li, Zheng Li, Peng Liu, Yang Wang, Qingyu Tang, Jianping Ding, Yingying Jia, Zhangcheng Chen, Lin Li, Yan Sun, Xiuxue Li, Qing Dai, Chun-Xiao Song, Kangling Zhang, Chuan He, Guo-Liang Xu
Science. Author manuscript; available in PMC 2012 Oct 2.
Published in final edited form as: Science. 2011 Sep 2; 333(6047): 1303–1307. Published online 2011 Aug 4. doi: 10.1126/science.1210944
PMCID:
PMC3462231
AbstractArticlePDF–846K
11.
Thymine DNA Glycosylase Is Essential for Active DNA Demethylation by Linked Deamination-Base Excision Repair
Salvatore Cortellino, Jinfei Xu, Mara Sannai, Robert Moore, Elena Caretti, Antonio Cigliano, Madeleine Le Coz, Karthik Devarajan, Andy Wessels, Dianne Soprano, Lara K. Abramowitz, Marisa S. Bartolomei, Florian Rambow, Maria Rosaria Bassi, Tiziana Bruno, Maurizio Fanciulli, Catherine Renner, Andres J. Klein-Szanto, Yoshihiro Matsumoto, Dominique Kobi, Irwin Davidson, Christophe Alberti, Lionel Larue, Alfonso Bellacosa
Cell. Author manuscript; available in PMC 2012 Jul 8.
Published in final edited form as: Cell. 2011 Jul 8; 146(1): 67–79. Published online 2011 Jun 30. doi: 10.1016/j.cell.2011.06.020
PMCID:
PMC3230223
AbstractArticlePDF–3.1M
12.
UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation
Henrik Sahlin Pettersen, Torkild Visnes, Cathrine Broberg Vågbø, Eva. K. Svaasand, Berit Doseth, Geir Slupphaug, Bodil Kavli, Hans E. Krokan
Nucleic Acids Res. 2011 Oct; 39(19): 8430–8444. Published online 2011 Jul 9. doi: 10.1093/nar/gkr563
PMCID:
PMC3201877
AbstractArticlePDF–1.5M
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
14.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
15.
Opposing regulatory roles of phosphorylation and acetylation in DNA mispair processing by thymine DNA glycosylase
Ryan D. Mohan, David W. Litchfield, Joseph Torchia, Marc Tini
Nucleic Acids Res. 2010 Mar; 38(4): 1135–1148. Published online 2009 Dec 4. doi: 10.1093/nar/gkp1097
PMCID:
PMC2831317
AbstractArticlePDF–5.8M
16.
Characterization of Dnmt3b:thymine-DNA glycosylase interaction and stimulation of thymine glycosylase-mediated repair by DNA methyltransferase(s) and RNA
Michael J. Boland, Judith K. Christman
J Mol Biol. Author manuscript; available in PMC 2009 Jul 2.
Published in final edited form as: J Mol Biol. 2008 Jun 6; 379(3): 492–504. Published online 2008 Feb 29. doi: 10.1016/j.jmb.2008.02.049
PMCID:
PMC2705441
AbstractArticlePDF–1.0M
17.
Base Excision by Thymine DNA Glycosylase Mediates DNA-Directed Cytotoxicity of 5-Fluorouracil
Christophe Kunz, Frauke Focke, Yusuke Saito, David Schuermann, Teresa Lettieri, Jim Selfridge, Primo Schär
PLoS Biol. 2009 Apr; 7(4): e1000091. Published online 2009 Apr 28. doi: 10.1371/journal.pbio.1000091
PMCID:
PMC2671560
AbstractArticle
18.
Thymine DNA Glycosylase Represses Myocardin-induced Smooth Muscle Cell Differentiation by Competing with Serum Response Factor for Myocardin Binding
Jiliang Zhou, Emily K. Blue, Guoqing Hu, B. Paul Herring
J Biol Chem. 2008 Dec 19; 283(51): 35383–35392. doi: 10.1074/jbc.M805489200
PMCID:
PMC2602901
AbstractArticlePDF–834K
19.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
20.
Association of Dnmt3a and thymine DNA glycosylase links DNA methylation with base-excision repair
Ya-Qiang Li, Ping-Zhu Zhou, Xiu-Dan Zheng, Colum P. Walsh, Guo-Liang Xu
Nucleic Acids Res. 2007 Jan; 35(2): 390–400. Published online 2006 Dec 14. doi: 10.1093/nar/gkl1052
PMCID:
PMC1802599
AbstractArticlePDF–3.3M

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