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Items: 1 to 20 of 129

1.
Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators
Jirko Kühnisch, Simon Theisen, Josephine Dartsch, Raphaela Fritsche-Guenther, Marieluise Kirchner, Benedikt Obermayer, Anna Bauer, Anne-Karin Kahlert, Michael Rothe, Dieter Beule, Arnd Heuser, Philipp Mertins, Jennifer A Kirwan, Nikolaus Berndt, Calum A MacRae, Norbert Hubner, Sabine Klaassen
Cardiovasc Res. 2023 Dec; 119(18): 2902–2916. Published online 2023 Oct 16. doi: 10.1093/cvr/cvad154
PMCID:
PMC10874277
AbstractArticlePDF–1.5M
2.
Discovery of PRDM16‐Mediated TRPA1 Induction as the Mechanism for Low Tubulo‐Interstitial Fibrosis in Diabetic Kidney Disease
Fang Xu, Hongwei Jiang, Xiaozhou Li, Jian Pan, Huiling Li, Luxiang Wang, Pan Zhang, Junxiang Chen, Shuangfa Qiu, Yuxin Xie, Yijian Li, Dongshan Zhang, Zheng Dong
Adv Sci (Weinh) 2024 Feb; 11(7): 2306704. Published online 2023 Dec 10. doi: 10.1002/advs.202306704
PMCID:
PMC10870028
AbstractArticlePDF–21M
3.
PRDM16 regulates γδT17 cell differentiation via controlling type 17 program and lipid-dependent cell fitness
Jinwoo Nah, Youngjin Lee, Rho H. Seong
Front Immunol. 2023; 14: 1332386. Published online 2024 Jan 4. doi: 10.3389/fimmu.2023.1332386
PMCID:
PMC10794300
AbstractArticlePDF–3.1M
4.
PRDM16 Deletion Is Associated with Sex-dependent Cardiomyopathy & Cardiac Mortality: A Translational, Multi-institutional Cohort Study
Ryan J. Kramer, Amir Nima Fatahian, Alice Chan, Jeffery Mortenson, Jennifer Osher, Bo Sun, Lauren E. Parker, Michael B. Rosamilia, Kyra B. Potter, Kaila Moore, Sage L. Atkins, Jill A. Rosenfeld, Alona Birjiniuk, Edward Jones, Taylor S. Howard, Jeffrey J. Kim, Daryl A. Scott, Seema Lalani, Omid MT. Rouzbehani, Samantha Kaplan, Marissa A. Hathaway, Jennifer L. Cohen, S. Yukiko Asaki, Hugo R. Martinez, Sihem Boudina, Andrew P. Landstrom
Circ Genom Precis Med. Author manuscript; available in PMC 2024 Aug 1.
Published in final edited form as: Circ Genom Precis Med. 2023 Aug; 16(4): 390–400. Published online 2023 Jul 3. doi: 10.1161/CIRCGEN.122.003912
PMCID:
PMC10528350
AbstractArticlePDF–1.5M
5.
PRDM16 deficiency in vascular smooth muscle cells aggravates abdominal aortic aneurysm
Zhenguo Wang, Xiangjie Zhao, Guizhen Zhao, Yanhong Guo, Haocheng Lu, Wenjuan Mu, Juan Zhong, Minerva Garcia-Barrio, Jifeng Zhang, Y. Eugene Chen, Lin Chang
JCI Insight. 2023 Jun 8; 8(11): e167041. Published online 2023 Jun 8. doi: 10.1172/jci.insight.167041
PMCID:
PMC10393233
AbstractArticlePDF–6.8M
6.
Androgen Receptor is a Negative Regulator of PRDM16 in Beige Adipocyte
Shiting Zhao, Tao Nie, Lei Li, Qiaoyun Long, Ping Gu, Yuwei Zhang, Wei Sun, Zexin Lin, Qing Liu, Yue Qi, Wei Wang, Mengyuan Xie, Kerry Loomes, Chenleng Cai, Donghai Wu, Hannah Xiaoyan Hui
Adv Sci (Weinh) 2023 Jul; 10(21): 2300070. Published online 2023 May 21. doi: 10.1002/advs.202300070
PMCID:
PMC10375129
AbstractArticlePDF–4.3M
7.
Exercise training remodels inguinal white adipose tissue through adaptations in innervation, vascularization, and the extracellular matrix
Pasquale Nigro, Maria Vamvini, Jiekun Yang, Tiziana Caputo, Li-Lun Ho, Nicholas P. Carbone, Danae Papadopoulos, Royce Conlin, Jie He, Michael F. Hirshman, Joseph D. White, Jacques Robidoux, Robert C. Hickner, Søren Nielsen, Bente K. Pedersen, Manolis Kellis, Roeland J.W. Middelbeek, Laurie J. Goodyear
Cell Rep. Author manuscript; available in PMC 2023 Jul 27.
Published in final edited form as: Cell Rep. 2023 Apr 25; 42(4): 112392. Published online 2023 Apr 13. doi: 10.1016/j.celrep.2023.112392
PMCID:
PMC10374102
AbstractArticlePDF–2.8M
8.
Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice
Anna Park, Kwang-eun Kim, Isaac Park, Sang Heon Lee, Kun-Young Park, Minkyo Jung, Xiaoxu Li, Maroun Bou Sleiman, Su Jeong Lee, Dae-Soo Kim, Jaehoon Kim, Dae-Sik Lim, Eui-Jeon Woo, Eun Woo Lee, Baek Soo Han, Kyoung-Jin Oh, Sang Chul Lee, Johan Auwerx, Ji Young Mun, Hyun-Woo Rhee, Won Kon Kim, Kwang-Hee Bae, Jae Myoung Suh
Nat Commun. 2023; 14: 3746. Published online 2023 Jun 23. doi: 10.1038/s41467-023-39106-z
PMCID:
PMC10290150
AbstractArticlePDF–1.7M
9.
PRDM16 regulates arterial development and vascular integrity
Michael Thompson, Masahide Sakabe, Mark Verba, Jiukuan Hao, Stryder M. Meadows, Q. Richard Lu, Mei Xin
Front Physiol. 2023; 14: 1165379. Published online 2023 Jun 1. doi: 10.3389/fphys.2023.1165379
PMCID:
PMC10267475
AbstractArticlePDF–4.4M
10.
Antagonism between Prdm16 and Smad4 specifies the trajectory and progression of pancreatic cancer
Eric Hurwitz, Parash Parajuli, Seval Ozkan, Celine Prunier, Thien Ly Nguyen, Deanna Campbell, Creighton Friend, Allyn Austin Bryan, Ting-Xuan Lu, Steven Christopher Smith, Mohammed Shawkat Razzaque, Keli Xu, Azeddine Atfi
J Cell Biol. 2023 Apr 3; 222(4): e202203036. Published online 2023 Feb 24. doi: 10.1083/jcb.202203036
PMCID:
PMC9999015
AbstractArticlePDF–12M
11.
Maternal exercise improves epithelial development of fetal intestine by enhancing apelin signaling and oxidative metabolism
Song Ah Chae, Jun Seok Son, Jeanene Marie de Avila, Min Du, Mei-Jun Zhu
Am J Physiol Regul Integr Comp Physiol. 2022 Nov 1; 323(5): R728–R738. Published online 2022 Oct 3. doi: 10.1152/ajpregu.00128.2022
PMCID:
PMC9829469
AbstractArticle
12.
PRDM16 expression and function in mammalian cochlear development
Michael Ebeid, Kathy Barnas, Hongji Zhang, Amal Yaghmour, Gabriele Noreikaite, Bryan C. Bjork
Dev Dyn. 2022 Oct; 251(10): 1666–1683. Published online 2022 May 7. doi: 10.1002/dvdy.480
PMCID:
PMC9790675
AbstractArticlePDF–17M
13.
Beiging of perivascular adipose tissue regulates its inflammation and vascular remodeling
Yusuke Adachi, Kazutaka Ueda, Seitaro Nomura, Kaoru Ito, Manami Katoh, Mikako Katagiri, Shintaro Yamada, Masaki Hashimoto, Bowen Zhai, Genri Numata, Akira Otani, Munetoshi Hinata, Yuta Hiraike, Hironori Waki, Norifumi Takeda, Hiroyuki Morita, Tetsuo Ushiku, Toshimasa Yamauchi, Eiki Takimoto, Issei Komuro
Nat Commun. 2022; 13: 5117. Published online 2022 Sep 7. doi: 10.1038/s41467-022-32658-6
PMCID:
PMC9452496
AbstractArticlePDF–2.1M
14.
Post-translational control of beige fat biogenesis by PRDM16 stabilization
Qiang Wang, Huixia Li, Kazuki Tajima, Anthony R. P. Verkerke, Zachary H. Taxin, Zhishuai Hou, Joanne B. Cole, Fei Li, Jake Wong, Ichitaro Abe, Rachana N. Pradhan, Tadashi Yamamuro, Takeshi Yoneshiro, Joel N. Hirschhorn, Shingo Kajimura
Nature. 2022; 609(7925): 151–158. Published online 2022 Aug 17. doi: 10.1038/s41586-022-05067-4
PMCID:
PMC9433319
AbstractArticlePDF–25M
15.
The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation
Ziyi Song, Alus M. Xiaoli, Youlei Li, Gerile Siqin, Tian Wu, Randy Strich, Jeffrey E. Pessin, Fajun Yang
Mol Metab. 2022 Oct; 64: 101548. Published online 2022 Jul 19. doi: 10.1016/j.molmet.2022.101548
PMCID:
PMC9386464
AbstractArticlePDF–6.6M
16.
A cardiac-null mutation of Prdm16 causes hypotension in mice with cardiac hypertrophy via increased nitric oxide synthase 1
Ji-One Kang, Tae Woong Ha, Hae-Un Jung, Ji Eun Lim, Bermseok Oh
PLoS One. 2022; 17(7): e0267938. Published online 2022 Jul 21. doi: 10.1371/journal.pone.0267938
PMCID:
PMC9302805
AbstractArticlePDF–2.8M
17.
The Effects of Maternal Intake of EPA and DHA Enriched Diet During Pregnancy and Lactation on Offspring’s Muscle Development and Energy Homeostasis
Saeed Ghnaimawi, Shilei Zhang, Jamie I. Baum, Yan Huang
Front Physiol. 2022; 13: 881624. Published online 2022 Jun 6. doi: 10.3389/fphys.2022.881624
PMCID:
PMC9207413
AbstractArticlePDF–6.0M
18.
Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse
Tatiana L Fonseca, Samuel C Russo, Cristina Luongo, Domenico Salvatore, Antonio C Bianco
Endocrinology. 2022 May; 163(5): bqac026. Published online 2022 Mar 3. doi: 10.1210/endocr/bqac026
PMCID:
PMC8988869
AbstractArticle
19.
PRDM paralogs antagonistically balance Wnt/β-catenin activity during craniofacial chondrocyte differentiation
Lomeli C. Shull, Ezra S. Lencer, Hyun Min Kim, Susumu Goyama, Mineo Kurokawa, James C. Costello, Kenneth Jones, Kristin B. Artinger
Development. 2022 Feb 15; 149(4): dev200082. Published online 2022 Feb 24. doi: 10.1242/dev.200082
PMCID:
PMC8918787
AbstractArticle
20.
PRDM16 Is a Compact Myocardium-Enriched Transcription Factor Required to Maintain Compact Myocardial Cardiomyocyte Identity in Left Ventricle
Tongbin Wu, Zhengyu Liang, Zengming Zhang, Canzhao Liu, Lunfeng Zhang, Yusu Gu, Kirk L. Peterson, Sylvia M. Evans, Xiang-Dong Fu, Ju Chen
Circulation. Author manuscript; available in PMC 2023 Feb 22.
Published in final edited form as: Circulation. 2022 Feb 22; 145(8): 586–602. Published online 2021 Dec 17. doi: 10.1161/CIRCULATIONAHA.121.056666
PMCID:
PMC8860879
AbstractArticlePDF–2.5M

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