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Items: 1 to 20 of 35

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Central Regulation of Brown Fat Thermogenesis in Response to Saturated or Unsaturated Long-Chain Fatty Acids
Anna Fosch, Maria Rodriguez-Garcia, Cristina Miralpeix, Sebastián Zagmutt, Maite Larrañaga, Ana Cristina Reguera, Jesus Garcia-Chica, Laura Herrero, Dolors Serra, Nuria Casals, Rosalia Rodriguez-Rodriguez
Int J Mol Sci. 2023 Jan; 24(2): 1697. Published online 2023 Jan 15. doi: 10.3390/ijms24021697
PMCID:
PMC9866012
AbstractArticlePDF–5.9M
3.
Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status
Cristina Miralpeix, Ana Cristina Reguera, Anna Fosch, Maria Casas, Jaume Lillo, Gemma Navarro, Rafael Franco, Josefina Casas, Stephen P.H. Alexander, Núria Casals, Rosalía Rodríguez‐Rodríguez
Br J Pharmacol. 2021 Apr; 178(7): 1507–1523. Published online 2021 Feb 12. doi: 10.1111/bph.15377
PMCID:
PMC9328656
AbstractArticlePDF–8.5M
4.
Nutrient Transporter Gene Expression in the Early Conceptus—Implications From Two Mouse Models of Diabetic Pregnancy
Claudia Kappen, Claudia Kruger, Sydney Jones, J. Michael Salbaum
Front Cell Dev Biol. 2022; 10: 777844. Published online 2022 Apr 11. doi: 10.3389/fcell.2022.777844
PMCID:
PMC9035823
AbstractArticlePDF–5.7M
5.
Carnitine palmitoyltransferase 1 (CPT1) alleviates oxidative stress and apoptosis of hippocampal neuron in response to beta-Amyloid peptide fragment Aβ25-35
Yiyun Ding, Hongxia Zhang, Zhaojun Liu, Qiuping Li, Yujiao Guo, Ye Chen, Yue Chang, Hongyan Cui
Bioengineered. 2021; 12(1): 5440–5449. Published online 2021 Aug 23. doi: 10.1080/21655979.2021.1967032
PMCID:
PMC8806834
AbstractArticlePDF–2.5M
6.
Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking
Maria Casas, Rut Fadó, José Luis Domínguez, Aina Roig, Moena Kaku, Shigeru Chohnan, Montse Solé, Mercedes Unzeta, Alfredo Jesús Miñano-Molina, José Rodríguez-Álvarez, Eamonn James Dickson, Núria Casals
J Cell Biol. 2020 Oct 5; 219(10): e201912045. Published online 2020 Sep 15. doi: 10.1083/jcb.201912045
PMCID:
PMC7659714
AbstractArticlePDF–7.5M
7.
CPT1C in the ventromedial nucleus of the hypothalamus is necessary for brown fat thermogenesis activation in obesity
Rosalía Rodríguez-Rodríguez, Cristina Miralpeix, Anna Fosch, Macarena Pozo, María Calderón-Domínguez, Xavier Perpinyà, Miquel Vellvehí, Miguel López, Laura Herrero, Dolors Serra, Núria Casals
Mol Metab. 2019 Jan; 19: 75–85. Published online 2018 Nov 2. doi: 10.1016/j.molmet.2018.10.010
PMCID:
PMC6323189
AbstractArticlePDF–1.2M
8.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
9.
Mechanisms of CPT1C-Dependent AMPAR Trafficking Enhancement
Esther Gratacòs-Batlle, Mireia Olivella, Nuria Sánchez-Fernández, Natalia Yefimenko, Federico Miguez-Cabello, Rut Fadó, Núria Casals, Xavier Gasull, Santiago Ambrosio, David Soto
Front Mol Neurosci. 2018; 11: 275. Published online 2018 Aug 8. doi: 10.3389/fnmol.2018.00275
PMCID:
PMC6092487
AbstractArticlePDF–3.2M
10.
Mutation in CPT1C Associated With Pure Autosomal Dominant Spastic Paraplegia
Carlo Rinaldi, Thomas Schmidt, Alan J. Situ, Janel O. Johnson, Philip R. Lee, Ke-lian Chen, Laura C. Bott, Rut Fadó, George H. Harmison, Sara Parodi, Christopher Grunseich, Benoît Renvoisé, Leslie G. Biesecker, Giuseppe De Michele, Filippo M. Santorelli, Alessandro Filla, Giovanni Stevanin, Alexandra Dürr, Alexis Brice, Núria Casals, Bryan J. Traynor, Craig Blackstone, Tobias S. Ulmer, Kenneth H. Fischbeck
JAMA Neurol. Author manuscript; available in PMC 2017 Sep 25.
Published in final edited form as: JAMA Neurol. 2015 May; 72(5): 561–570. doi: 10.1001/jamaneurol.2014.4769
Correction in:
JAMA Neurol. 2015 May; 72(5): 608.
PMCID:
PMC5612424
AbstractArticlePDF–1.3M
11.
AMPA-receptor specific biogenesis complexes control synaptic transmission and intellectual ability
Aline Brechet, Rebecca Buchert, Jochen Schwenk, Sami Boudkkazi, Gerd Zolles, Karine Siquier-Pernet, Irene Schaber, Wolfgang Bildl, Abdelkrim Saadi, Christine Bole-Feysot, Patrick Nitschke, Andre Reis, Heinrich Sticht, Nouriya Al-Sanna’a, Arndt Rolfs, Akos Kulik, Uwe Schulte, Laurence Colleaux, Rami Abou Jamra, Bernd Fakler
Nat Commun. 2017; 8: 15910. Published online 2017 Jul 4. doi: 10.1038/ncomms15910
PMCID:
PMC5500892
AbstractArticlePDF–4.3M
12.
Differential gene regulation of GHSR signaling pathway in the arcuate nucleus and NPY neurons by fasting, diet-induced obesity, and 17β-estradiol
Ali Yasrebi, Anna Hsieh, Kyle J. Mamounis, Elizabeth A. Krumm, Jennifer A. Yang, Jason Magby, Pu Hu, Troy A. Roepke
Mol Cell Endocrinol. Author manuscript; available in PMC 2017 Feb 15.
Published in final edited form as: Mol Cell Endocrinol. 2016 Feb 15; 422: 42–56. Published online 2015 Nov 11. doi: 10.1016/j.mce.2015.11.007
PMCID:
PMC4742417
AbstractArticlePDF–1.6M
13.
Novel Regulation of the Synthesis of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Subunit GluA1 by Carnitine Palmitoyltransferase 1C (CPT1C) in the Hippocampus
Rut Fadó, David Soto, Alfredo J. Miñano-Molina, Macarena Pozo, Patricia Carrasco, Natalia Yefimenko, José Rodríguez-Álvarez, Núria Casals
J Biol Chem. 2015 Oct 16; 290(42): 25548–25560. Published online 2015 Sep 3. doi: 10.1074/jbc.M115.681064
PMCID:
PMC4646200
AbstractArticlePDF–1.8M
14.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
15.
BRAIN-SPECIFIC CARNITINE PALMITOYLTRANSFERASE-1C: ROLE IN CNS FATTY ACID METABOLISM, FOOD INTAKE AND BODY WEIGHT
Michael J. Wolfgang, Seung Hun Cha, David S. Millington, Gary Cline, Gerald I Shulman, Akira Suwa, Makoto Asaumi, Takeshi Kurama, Teruhiko Shimokawa, M. Daniel Lane
J Neurochem. Author manuscript; available in PMC 2014 Jan 11.
Published in final edited form as: J Neurochem. 2008 May; 105(4): 1550–1559. Published online 2008 Jan 28. doi: 10.1111/j.1471-4159.2008.05255.x
PMCID:
PMC3888516
AbstractArticlePDF–1.3M
16.
Hypothalamic Ceramide Levels Regulated by CPT1C Mediate the Orexigenic Effect of Ghrelin
Sara Ramírez, Luís Martins, Jordi Jacas, Patricia Carrasco, Macarena Pozo, Josep Clotet, Dolors Serra, Fausto G. Hegardt, Carlos Diéguez, Miguel López, Núria Casals
Diabetes. 2013 Jul; 62(7): 2329–2337. Published online 2013 Jun 14. doi: 10.2337/db12-1451
PMCID:
PMC3712075
AbstractArticlePDF–915K
17.
Depletion of the novel p53-target gene carnitine palmitoyltransferase 1C delays tumor growth in the neurofibromatosis type I tumor model
N Sanchez-Macedo, J Feng, B Faubert, N Chang, A Elia, E J Rushing, K Tsuchihara, D Bungard, S L Berger, R G Jones, T W Mak, K Zaugg
Cell Death Differ. 2013 Apr; 20(4): 659–668. Published online 2013 Feb 15. doi: 10.1038/cdd.2012.168
PMCID:
PMC3595492
AbstractArticlePDF–2.6M
18.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
19.
Metabolomic profiling reveals a role for CPT1c in neuronal oxidative metabolism
Jieun Lee, Michael J Wolfgang
BMC Biochem. 2012; 13: 23. Published online 2012 Oct 25. doi: 10.1186/1471-2091-13-23
PMCID:
PMC3523003
AbstractArticlePDF–1.3M
20.
Ceramide Levels Regulated by Carnitine Palmitoyltransferase 1C Control Dendritic Spine Maturation and Cognition
Patricia Carrasco, Ignasi Sahún, Jerome McDonald, Sara Ramírez, Jordi Jacas, Esther Gratacós, Adriana Y. Sierra, Dolors Serra, Laura Herrero, Amparo Acker-Palmer, Fausto G. Hegardt, Mara Dierssen, Núria Casals
J Biol Chem. 2012 Jun 15; 287(25): 21224–21232. Published online 2012 Apr 26. doi: 10.1074/jbc.M111.337493
PMCID:
PMC3375544
AbstractArticlePDF–1.7M

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